Topoisomerase i poisoning results in PARP-mediated replication fork reversal

Nature Structural and Molecular Biology

Volumn 19, Issue 4, 2012, Pages 417-423

  Ray Chaudhuri, Arnab ^a   Hashimoto, Yoshitami ^b,e   Herrador, Raquel ^a,e   Neelsen, Kai J ^a   Fachinetti, Daniele ^c,d   Bermejo, Rodrigo ^c,e   Cocito, Andrea ^c   Costanzo, Vincenzo ^b   Lopes, Massimo ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b Clare Hall Laboratories   (United Kingdom)

^c FIRC INSTITUTE OF MOLECULAR ONCOLOGY   (Italy)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF SALAMANCA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

DNA TOPOISOMERASE; DNA TOPOISOMERASE INHIBITOR; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; CAMPTOTHECIN; DNA;

ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CHROMOSOME BREAKAGE; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; DNA DAMAGE CHECKPOINT; DNA REPLICATION; DNA STRAND BREAKAGE; DNA TRANSCRIPTION; ENZYME ACTIVITY; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; YEAST; ANIMAL; CELL LINE; CHEMISTRY; CONFORMATION; CYTOLOGY; DNA REPAIR; DRUG EFFECT; HUMAN; METABOLISM; XENOPUS LAEVIS;

MAMMALIA; XENOPUS LAEVIS;

ANIMALS; CAMPTOTHECIN; CELL LINE; DNA; DNA REPAIR; DNA REPLICATION; DNA TOPOISOMERASES, TYPE I; HUMANS; NUCLEIC ACID CONFORMATION; POLY(ADP-RIBOSE) POLYMERASES; SACCHAROMYCES CEREVISIAE; TOPOISOMERASE I INHIBITORS; XENOPUS LAEVIS;

EID: 84861322877     PISSN: 15459993     EISSN: 15459985     Source Type: Journal    
DOI: 10.1038/nsmb.2258     Document Type: Article

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