Deficiency of ATF3, an adaptive-response gene, protects islets and ameliorates inflammation in a syngeneic mouse transplantation model

Diabetologia

Volumn 53, Issue 7, 2010, Pages 1438-1450

  Zmuda, E J ^a   Viapiano, M ^a   Grey, S T ^b   Hadley, G ^a   Garcia Ocana A ^c   Hai, T ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b GARVAN INSTITUTE OF MEDICAL RESEARCH   (Australia)

^c UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

ATF3; Cell death; Inflammation; Islet transplantation; Primary non function; Stress response; Transcription factor

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 3; CASPASE 3; INTERLEUKIN 1BETA; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; PROTEIN BNIP3; PROTEIN NOXA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL ISOLATION; CELL PROTECTION; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVATION; GENE EXPRESSION; GENE FUNCTION; GENE SILENCING; GENETIC CODE; GLUCOSE HOMEOSTASIS; GRAFT REJECTION; HYPOXIA; IMMUNOMODULATION; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; ISOGRAFT; MALE; MOUSE; NONHUMAN; PANCREAS ISLET TRANSPLANTATION; PRIORITY JOURNAL; RAT; STRESS; UPREGULATION; WILD TYPE;

ACTIVATING TRANSCRIPTION FACTOR 3; ANIMALS; APOPTOSIS; CELL LINE; CHROMATIN IMMUNOPRECIPITATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; GRAFT REJECTION; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IMMUNOMODULATION; INFLAMMATION; ISLETS OF LANGERHANS TRANSPLANTATION; MICE; MICE, KNOCKOUT; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSPLANTATION, ISOGENEIC;

EID: 77954828927     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-010-1696-x     Document Type: Article

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