Global gene expression profiling of pancreatic islets in mice during streptozotocin-induced β-cell damage and pancreatic Glp-1 gene therapy

DMM Disease Models and Mechanisms

Volumn 6, Issue 5, 2013, Pages 1236-1245

  Tonne, Jason M ^a   Sakuma, Toshie ^a   Deeds, Michael C ^a   Munoz Gomez, Miguel ^a   Barry, Michael A ^a   Kudva, Yogish C ^a   Ikeda, Yasuhiro ^a  

^a MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 1; GLUCAGON LIKE PEPTIDE 1; HYBRID PROTEIN; INSULIN; PARVOVIRUS VECTOR; PROTEIN P53; REG3B GLUCAGON LIKE PEPTIDE 1; STREPTOZOCIN; TRANSCRIPTION FACTOR NKX6.1; UNCLASSIFIED DRUG;

ABCC8 GENE; ADENO ASSOCIATED VIRUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL DAMAGE; CELL FUNCTION; CELL PROTECTION; CELL SURVIVAL; CONTROLLED STUDY; DIABETES MELLITUS; FKBP1B GENE; G6PC2 GENE; GAD1 GENE; GENE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE TARGETING; GLP1 GENE; HYPERGLYCEMIA; ISL1 GENE; MOUSE; NEUROD1 GENE; NONHUMAN; PANCREAS ISLET; PANCREAS ISLET BETA CELL; PDX1 GENE; PRIORITY JOURNAL; PRSS53 GENE; SLC2A2 GENE; SLC30A8 GENE; STREPTOZOCIN DIABETES; TMEM229B GENE; TTC28 GENE; UCN3 GENE; UPREGULATION; VDR GENE; VIRAL GENE THERAPY;

ANIMALS; DEPENDOVIRUS; DIABETES MELLITUS, EXPERIMENTAL; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC THERAPY; GENETIC VECTORS; GLUCAGON-LIKE PEPTIDE 1; HEK293 CELLS; HUMANS; HYPERGLYCEMIA; INSULIN; INSULIN-SECRETING CELLS; MICE; MICE, INBRED C57BL; PROTEINS; STREPTOZOCIN; TRANSCRIPTOME; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84883868959     PISSN: 17548403     EISSN: 17548411     Source Type: Journal    
DOI: 10.1242/dmm.012591     Document Type: Article

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