The Structure of an NDR/LATS Kinase–Mob Complex Reveals a Novel Kinase–Coactivator System and Substrate Docking Mechanism

PLoS Biology

Volumn 13, Issue 5, 2015, Pages

  Gógl, Gergő ^a,b   Schneider, Kyle D ^c   Yeh, Brian J ^c   Alam, Nashida ^c   Nguyen Ba, Alex N ^d   Moses, Alan M ^d   Hetényi, Csaba ^a   Reményi, Attila ^a   Weiss, Eric L ^c  

^a INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

^b EÖTVÖS LORÁND UNIVERSITY   (Hungary)

^c NORTHWESTERN UNIVERSITY   (United States)

^d UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN KINASE CBK1; PROTEIN KINASE MOB2; PROTEIN SERINE THREONINE KINASE; UNCLASSIFIED DRUG; CBK1 PROTEIN, S CEREVISIAE; CELL CYCLE PROTEIN; MOB2 PROTEIN, S CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEIN; SIGNAL PEPTIDE;

ARTICLE; CELL GROWTH; CONTROLLED STUDY; CYTOKINESIS; ENZYME ACTIVATION; ENZYME MECHANISM; ENZYME PHOSPHORYLATION; ENZYME REGULATION; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; IN VIVO STUDY; MOLECULAR DOCKING; NONHUMAN; SIGNAL TRANSDUCTION; CHEMISTRY; CONSERVED SEQUENCE; METABOLISM; PHOSPHORYLATION; PROTEIN MOTIF; SACCHAROMYCES CEREVISIAE;

EUKARYOTA; SACCHAROMYCETALES;

AMINO ACID MOTIFS; CELL CYCLE PROTEINS; CONSERVED SEQUENCE; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MOLECULAR DOCKING SIMULATION; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 84930638281     PISSN: 15449173     EISSN: 15457885     Source Type: Journal    
DOI: 10.1371/journal.pbio.1002146     Document Type: Article

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