Crystal structure of a human Mob1 protein: Toward understanding Mob-regulated cell cycle pathways

Structure

Volumn 11, Issue 9, 2003, Pages 1163-1170

  Stavridi, Elena S ^a   Harris, Kimberly G ^a   Huyen, Yentram ^a,b   Bothos, John ^a,b   Verwoerd, Peter Mark ^b   Stayrook, Steve E ^b   Pavletich, Nikola P ^c,d   Jeffrey, Philip D ^c   Luca, Francis C ^b  

^a WISTAR INSTITUTE   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^d HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CYCLE PROTEIN; FUNGAL PROTEIN; PHOSPHOTRANSFERASE; PROTEIN MOB1; SOLVENT; UNCLASSIFIED DRUG; ZINC;

ALLELE; AMINO TERMINAL SEQUENCE; ARTICLE; CELL CYCLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; ELECTRICITY; MOLECULAR CLONING; MOLECULAR INTERACTION; MUTANT; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN SECONDARY STRUCTURE; PROTEIN STABILITY; PROTEIN STRUCTURE; PROTEIN TERTIARY STRUCTURE; REGULATORY MECHANISM; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION; X RAY CRYSTALLOGRAPHY;

EUKARYOTA; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 0042835771     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-2126(03)00182-5     Document Type: Article

References (28)

1. Altschul S.F., Gish W., Miller W., Myers E.W., Lipman D.J. Basic local alignment search tool. J. Mol. Biol. 215:1990;403-410.
2. Baillat G., Moqrich A., Castets F., Baude A., Bailly Y., Benmerah A., Monneron A. Molecular cloning and characterization of phocein, a protein found from the Golgi complex to dendritic spines. Mol. Biol. Cell. 12:2001;663-673.
3. Baillat G., Gaillard S., Castets F., Monneron A. Interactions of phocein with nucleoside-diphosphate kinase, Eps15, and Dynamin I. J. Biol. Chem. 277:2002;18961-18966.
4. Bardin A.J., Amon A. Men and sin. what's the difference? Nat. Rev. Mol. Cell Biol. 2:2001;815-826.
5. Brünger A.T., Adams P.D., Clore G.M., Delano W.L., Gros P., Grosse-Kunstleve R.W., Jiang J.-S., Kuszewski J., Nilges M., Pannu N.S.et al. Crystallography and NMR System. A new software suite for macromolecular structure determination Acta Crystallogr. D Biol. Crystallogr. 54:1998;905-921.
6. CCP4 The CCP4 (Collaborative Computational Project 4) suite. programs for protein crystallography Acta Crystallogr. D Biol. Crystallogr. 50:1994;760-763.
7. Colman-Lerner A., Chin T.E., Brent R. Yeast Cbk1 and Mob2 activate daughter-specific genetic programs to induce asymmetric cell fates. Cell. 107:2001;739-750.
8. Hennebold J.D., Tanaka M., Saito J., Hanson B.R., Adashi E.Y. Ovary-selective genes I. the generation and characterization of an ovary-selective complementary deoxyribonucleic acid library Endocrinology. 141:2000;2725-2734.
9. Hou M.C., Salek J., McCollum D. Mob1p interacts with the Sid2p kinase and is required for cytokinesis in fission yeast. Curr. Biol. 10:2000;619-622.
10. Hou M.C., Wiley D.J., Verde F., McCollum D. Mob2p interacts with the protein kinase Orb6p to promote coordination of cell polarity with cell cycle progression. J. Cell Sci. 116:2003;125-135.
11. Jeffrey P.D., Russo A.A., Polyak K., Gibbs E., Hurwitz J., Massague J., Pavletich N.P. Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex. Nature. 376:1995;313-320.
12. Jones T.A., Zou J.Y., Cowan S.W., Kjeldgaard M. Improved methods for binding protein models in electron density maps and the location of errors in these models. Acta Crystallogr. A. 47:1991;110-119.
13. Komarnitsky S.I., Chiang Y.C., Luca F.C., Chen J., Toyn J.H., Winey M., Johnston L.H., Denis C.L. DBF2 protein kinase binds to and acts through the cell cycle-regulated MOB1 protein. Mol. Cell. Biol. 18:1998;2100-2107.
14. Kraulis P. Molscript. A program to produce both detailed and schematic plots of protein structures J. Appl. Crystallogr. 24:1991;946-950.
15. Lee S.E., Frenz L.M., Wells N.J., Johnson A.L., Johnston L.H. Order of function of the budding-yeast mitotic exit-network proteins Tem1, Cdc15, Mob1, Dbf2, and Cdc5. Curr. Biol. 11:2001;784-788.
16. Luca F.C., Winey M. MOB1, an essential yeast gene required for completion of mitosis and maintenance of ploidy. Mol. Biol. Cell. 9:1998;29-46.
17. Luca F.C., Mody M., Kurischko C., Roof D.M., Giddings T.H., Winey M. Saccharomyces cerevisiae Mob1p is required for cytokinesis and mitotic exit. Mol. Cell. Biol. 21:2001;6972-6983.
18. Mah A.S., Jang J., Deshaies R.J. Protein kinase Cdc15 activates the Dbf2-Mob1 kinase complex. Proc. Natl. Acad. Sci. USA. 98:2001;7325-7330.
19. McCollum D., Gould K.L. Timing is everything. regulation of mitotic exit and cytokinesis by the MEN and SIN Trends Cell Biol. 11:2001;89-95.
20. Merritt E.A., Bacon D.J. Raster3D-photorealistic molecular graphics. Methods Enzymol. 277:1997;505-524.
21. Moreno C.S., Lane W.S., Pallas D.C. A mammalian homolog of yeast MOB1 is both a member and a putative substrate of striatin family-protein phosphatase 2A complexes. J. Biol. Chem. 276:2001;24253-24260.
22. Morgan D.O. The dynamics of cyclin dependent kinase structure. Curr. Opin. Cell Biol. 8:1996;767-772.
23. Morris R.J., Perrakis A., Lamzin V.S. ARP/wARP's model-building algorithms. I. The main chain. Acta Crystallogr. D Biol. Crystallogr. 58:2002;968-975.
24. Nicholls A., Sharp K.A., Honig B. Protein folding and association. insights from the interfacial and thermodynamic properties of hydrocarbons Proteins. 11:1991;281-296.
25. Otwinowski Z., Minor W. Processing of X-ray diffraction data collected in oscillation mode. Methods Enzymol. 276:1997;307-326.
26. Salimova E., Sohrmann M., Fournier N., Simanis V. The S. pombe orthologue of the S. cerevisiae mob1 gene is essential and functions in signalling the onset of septum formation. J. Cell Sci. 113:2000;1695-1704.
27. Schneider T.R., Sheldrick G.M. Substructure solution with SHELXD. Acta Crystallogr. D Biol. Crystallogr. 58:2002;1772-1779.
28. Weiss E.L., Kurischko C., Zhang C., Shokat K., Drubin D.G., Luca F.C. The Saccharomyces cerevisiae Mob2p-Cbk1p kinase complex promotes polarized growth and acts with the mitotic exit network to facilitate daughter cell-specific localization of Ace2p transcription factor. J. Cell Biol. 158:2002;885-900.