Associations among PH and SH3 domain-containing proteins and Rho-type GTPases in yeast

Journal of Cell Biology

Volumn 133, Issue 4, 1996, Pages 879-894

  Bender, Laurel ^a   Shuen Lo, H ^a   Lee, Heng ^a   Kokojan, Vance ^a   Peterson, Julie ^a,b   Bender, Alan ^a  

^a INDIANA UNIVERSITY   (United States)

^b BLOOD RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BINDING SITE; GENE EXPRESSION; MORPHOGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; YEAST;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID SEQUENCE; BASE SEQUENCE; BLOOD PROTEINS; CARRIER PROTEINS; CDC42 GTP-BINDING PROTEIN, SACCHAROMYCES CEREVISIAE; CELL CYCLE PROTEINS; DNA, FUNGAL; FUNGAL PROTEINS; GTP PHOSPHOHYDROLASES; GTP-BINDING PROTEINS; MOLECULAR SEQUENCE DATA; MUTATION; PHENOTYPE; PHOSPHOPROTEINS; PROTEIN BINDING; RHO GTP-BINDING PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SRC HOMOLOGY DOMAINS;

SACCHAROMYCES CEREVISIAE;

EID: 15844384186     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.133.4.879     Document Type: Article

References (66)

1. Adams, A.E.M., D.I. Johnson, R.M. Longnecker, B.F. Sloat, and J.R. Pringle. 1990. CDC42 and CDC43, two additional genes involved in budding and the establishment of cell polarity in the yeast Saccharomyces cerevisiae. J. Cell Biol. 111:131-142.
2. Alani, E., L. Cao, and N. Kleckner. 1987. A method for gene disruption that allows repeated use of URA3 selection in the construction of multiply disrupted yeast strains. Genetics. 116:541-545.
3. Bartel, P., C.-T. Chien, R. Sternglanz, and S. Fields. 1993. Using the two-hybrid system to detect protein-protein interactions. In Cellular Interactions in Development: A Practical Approach. D.A. Hartley, editor. Oxford Univ. Press, Oxford. 153-179.
4. Bauer, F., M. Urdaci, M. Aigle, and M. Crouzet. 1993. Alteration of a yeast SH3 protein leads to conditional viability with defects in cytoskeletal and budding patterns. Mol. Cell Biol. 13:5070-5084.
5. Bender, A., and J.R. Pringle. 1989. Multicopy suppression of the cdc24 budding defect in yeast by CDC42 and three newly identified genes including the ras-related gene RSR1. Proc. Natl. Acad. Sci. USA. 86:9976-9980.
6. Bender A., and J.R. Pringle. 1991. Use of a screen for synthetic lethal and multicopy suppression mutants to identify two new genes involved in morphogenesis in Saccharomyces cerevisiae. Mol. Cell Biol. 11:1295-1305.
7. Bender, A., and G.F. Sprague, Jr. 1989. Pheromones and pheromone receptors are the primary determinants of mating specificity in the yeast Saccharomyces cerevisiae. Genetics. 121:463-476.
8. Benovic, J.L., A. DeBlasi, W.C. Stone, M.G. Caron, and R.J. Lefkowitz. 1989. β-adrenergic receptor kinase: primary structure delineates a multigene family. Science (Wash. DC). 246:235-240.
9. Botstein, D., S.C. Falco, S.E. Stewart, M. Brennan, S. Scherer, D.T. Stinchcomb, K. Struhl, and R.W. Davis. 1979. Sterile host yeasts (SHY): a eukaryotic system of biological containment for recombinant DNA experiments. Gene (Amst.). 8:17-24.
10. Bradford, M.M. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein using the principle of protein-dye binding. Anal. Biochem. 72:248-254.
11. Broach, J.R., J.N. Strathern, and J.B. Hicks. 1979. Transformation in yeast: development of a hybrid cloning vector and isolation of the CAN1 gene. Gene (Amst.). 8:121-133.
12. Carlson, M. and D. Botstein. 1982. Two differentially regulated mRNAs with different 5′ ends encode secreted and intracellular forms of yeast invertase. Cell. 28:145-154.
13. Chang, E.G., M. Barr, Y. Wang, V. Jung, H.-P. Xu, and M.H. Wigler. 1994. Cooperative interaction of S. pombe proteins required for mating and morphogenesis. Cert. 79:131-141.
14. Chant, J., K. Corrado, J.R. Pringle, and I. Herskowitz. 1991. Yeast BUD5, encoding a putative GDP-GTP exchange factor, is necessary for bud site selection and interacts with bud formation gene BEM1. Cell. 65:1213-1224.
15. Chattoo, B.B., F. Sherman, D.A. Azubalis, T.A. Fjellstedt, D. Mehnert, and M. Ogur. 1979. Selection of lys2 mutants of the yeast Saccharomyces cerevisiae by the utilization of α-aminoadipate. Genetics. 93:51-65.
16. Chenevert, J., K. Corrado, A. Bender, J. Pringle, and I. Herskowitz. 1992. A yeast gene (BEM1) necessary for cell polarization whose product contains two SH3 domains. Nature (Lond.). 356:77-79.
17. Chenevert, J., N. Valtz, and I. Herskowitz. 1994. Identification of genes required for normal pheromone-induced cell polarization in Saccharomyces cerevisiae. Genetics. 136:1287-1297.
18. Chien, C.-T., P.L. Bartel, R. Sternglanz, and S. Fields. 1991. The two-hybrid system: a method to identify and clone genes for proteins that interact with a protein of interest. Proc. Natl. Acad. Sci. USA. 88:9578-9582.
19. Coso, O.A., M. Chiariello, J.-C. Yu, H. Teramoto, P. Crespo, N. Xu, T. Miki, and J.S. Gutkind. 1995. The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway. Cell. 81:1137-1146.
20. Cvrcková, F., C. De Virgilio, E. Manser, J.R. Pringle, and K. Nasmyth. 1995. Ste20-like protein kinases are required for normal localization of cell growth and for cytokinesis in budding yeast. Genes & Dev. 9:1817-1830.
21. Drubin, D.G., J. Mulholland, Z. Zhu, and D. Botstein. 1990. Homology of a yeast actin-binding protein to signal transduction proteins and myosin-I. Nature (Lond.). 343:288-290.
22. Gibson, T.J., M. Hyvonen, A. Musacchio, M. Saraste, and E. Birney. 1994. PH domain: the first anniversary. Trends Biochem. Sci. 19:349-353.
23. Golemis, E.A., J. Gyuris, and R. Brent. 1994. Interaction trap/two-hybrid system to identify interacting proteins. In Current Protocols. F.M. Ausubel, R. Brent, R.E. Kingston, D.D. Moore, J.G. Seidman, J.A. Smith, and K. Struhl, editors. John Wiley & Sons, New York. 13.14.1-13.14.17.
24. Guan, K.L., and J.E. Dixon. 1991. Eukarytotic proteins expressed in Escherichia coli: an improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase. Anal. Biochem. 192:262-267.
25. Harlan, J.E., P.J. Hajduk, H.S. Yoon, and S.W. Fesik. 1994. Pleckstrin homology domains hind to phosphatidylinositol-4,5-bisphosphate. Nature (Lond.). 371:168-170.
26. Harper, J.W., G.R. Adami, N. Wei, K. Keyomarsi. and S.J. Elledge. 1993. The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell. 75:805-816.
27. Holtzman, D.A., S. Yang, and D.G. Drubin. 1993. Synthetic-lethal interactions identify two novel genes, SLA1 and SLA2, that control membrane cytoskeleton assembly in Saccharomyces cerevisiae. J. Cell Biol. 122:635-644.
28. Imai, J., A. Toh-e, and Y. Matsui. 1996. Genetic analysis of the Saccharomyces cerevisiae RHO3 gene, encoding a Rho-type small GTPase, provides evidence for a role in bud formation. Genetics. 142:359-369.
29. Johnson, D.I., and J.R. Pringle. 1990. Molecular characterization of CDC42, a Saccharomyces cerevisiae gene involved in the development of cell polarity. J. Cell Biol. 111:143-152.
30. Keszenman-Pereyra, D., and K. Hieda. 1988. A colony procedure for transformation of Saccharomyces cerevisiae. Curr. Genet. 13:21-23.
31. Koshland, D., J.C. Kent, and L.H. Hartwell. 1985. Genetic analysis of the mitotic transmission of minichromosomes. Cell. 40:393-403.
32. Kozma, R., S. Ahmed, A. Best, and L. Lim. 1995. The Ras-related protein Cdc42Hs and bradykinin promote formation of peripheral actin microspikes and filopdia in Swiss 3T3 fibroblasts. Mol. Cell Biol. 15:1942-1952.
33. Lauze, E., B. Stoelcker, F.C. Luca, E. Weiss, A.R. Schutz, and M. Winey. 1995. Yeast spindle pole body duplication gene MPS1 encodes an essential dual specificity protein kinase. EMBO (Eur. Mol. Biol. Organ.) J. 14:1655-1663.
34. Liu, L., and B. Pohajdak. 1992. Cloning and sequencing of a human cDNA from cytolytic NK/T cells with homology to yeast SEC7. Biochim. Biophys. Acta. 1132:75-78.
35. Ma, H., S. Kunes, P.J. Schatz, and D. Botstein. 1987. Plasmid construction by homologous recombination in yeast. Gene (Amst.). 58:201-216.
36. Matsui, Y., and A. Toh-e. 1992a. Isolation and characterization of two novel ras superfamily genes in Saccharomyces cerevisiae. Gene (Amst.). 114:43-49.
37. Matsui, Y., and A. Toh-e. 1992b. Yeast RHO3 and RHO4 ras superfamily genes are necessary for bud growth, and their defect is suppressed by a high dose of bud formation genes CDC42 and BEM1. Mol. Cell. Biol. 12:5690-5699.
38. Matsui, Y., R. Matsui, R. Akada, and A. Toh-e. 1996. Yeast src homology region 3 domain-binding proteins involved in bud formation. J. Cell Biol. 133:865-878.
39. Mayer, B.J., R. Ren, K.L. Clark, and D. Baltimore. 1993. A putative modular domain present in diverse signaling proteins. Cell. 73:629-630.
40. Minden, A., A. Lin, F.-X. Claret, A. Abo, and M. Karin. 1995. Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs. Cell. 81:1147-1157.
41. Musacchio, A., T. Gibson, P. Rice, J. Thompson, and M. Saraste. (1993). The PH domain: a common piece in the structural patchwork of signalling proteins. Trends Biochem. Sci. 18:343-348.
42. Nobes, C.D., and A. Hall. 1995. Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia. Cell, 81:53-62.
43. Pawson, T. 1995. Protein modules and signalling networks. Nature (Lond.). 373:573-580.
44. Peterson, J., Y. Zheng, L. Bender, A. Myers, R. Cerione, and A. Bender. 1994. Interactions between the bud emergence proteins Bem1p and Bem2p and Rho-type GTPases in yeast. J. Cell Biol. 127:1395-1406.
45. Poch, O., E. Schwob, F. de Fraipont, A. Camasses, R. Bordonne, and R.P. Martin. 1994. RPK1, an essential yeast protein kinase involved in the regulation of the onset of mitosis, shows homology to mammalian dual-specificity kinases. Mol. Gen. Genet. 243:641-653.
46. Pringle, J.R., R.A. Preston, A.E.M. Adams, T. Stearns, D.G. Drubin, B.K. Haarer, and E.W. Jones. 1989. Fluorescence microscopy methods for yeast. Methods Cell Biol. 31:357-435.
47. Rawlings, D.J., D.C. Saffran, S. Tsukada, D.A. Largaespada, J.C. Grimaldi, L. Cohen, R.N. Mohr, J.F. Bazan, M. Howard, N.G. Copeland, N.A. Jenkins, and O.N. Witte. 1993. Mutation of unique region of Bruton's tyrosine kinase in immunodeficient XID mice. Science (Wash. DC). 261:358-361.
48. Ren, R., B.J. Mayer, P. Cicchetti, and D. Baltimore. 1993. Identification of a ten-amino acid proline-rich SH3 binding site. Science (Wash. DC). 259:1157-1161.
49. Reynolds, A., and V. Lundhlad. 1989. Yeast vectors and assays for expression of cloned genes. In Current Protocols, F.M. Ausubel, R. Brent, R.E. Kingston, D.D. Moore, J.G. Seidman, J.A. Smith, and K., Struhl, editors. John Wiley & Sons, New York. 13.6.1-13.6.4.
50. Rose, A.B., and J.R. Broach. 1990. Propagation and expression of cloned genes in yeast: 2-μm circle-based vectors. Methods Enzymol. 185:234-279.
51. Rose, M.D., P. Novick, J.H. Thomas, D. Botstein, and G.R. Fink. 1987. A Saccharomyces cerevisiae genomic plasmid bank based on a centromere-containing shuttle vector. Gene (Amst.). 60:237-243.
52. Sahr, K.E., P. Laurila, L. Kotula, A.L. Scarpa, E. Coupal, T.L. Leto, A.J. Linnenbach, J.C. Winkelmann, D.W. Speicher, V.T. Marchesi, et al., 1990. The complete cDNA and polypeptide sequences of human erythroid α-spectrin. J. Biol. Chem. 265:4434-4443.
53. Shou, C., C.L. Farnsworth, B.C. Neel, and L.A. Feig. 1992. Molecular cloning of cDNAs encoding a guanine-nucleotide-releasing factor for Ras p21. Nature(Lond.). 358:351-354.
54. Sikorski, R.S., and P. Hieter. 1989. A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics. 122:19-27.
55. Simon, M.-N., C. De Virgilio, B. Souza, J.R. Pringle, A. Abo, and S.I. Reed. 1995. Role for the Rho-family GTPase Cdc42 in yeast mating-phermone signal pathway. Nature (Lond.). 376:702-705.
56. Takeya, T., and H. Hanafusa. 1983. Structure and sequence of the cellular gene homologous to the RSV src gene and the mechanism for generating the transforming virus. Cell. 32:881-890.
57. Thomas, J.D., P. Sideras, C.I.E. Smith, I. Vorechovsky, V. Chapman, and W.E. Paul. 1993. Colocalization of X-linked agammaglobulinemia and X-linked immunodeficiency genes. Science (Wash. DC). 261:355-358.
58. Touhara, K., J. Inglese, J.A. Pitcher, G. Shaw, and R.J. Lefkowitz. 1994. Binding of G protein βγ-subunits to pleckstrin homology domains. J. Biol. Chem. 269:10217-10220.
59. Trahey, M., G. Wong, R. Halenbeck, B. Rubinfeld, G.A. Martin, M. Ladner, C.M. Long, W.J. Crosier, K. Watt, K. Koths, and F. McCormick. 1988. Molecular cloning of two types of GAP complementary DNA from human placenta. Science (Wash. DC). 242:1697-1700.
60. Tyers, M., R.A. Rachubinski, M.I. Stewart, A.M. Varrichio, R.G.L. Shorr, R.J. Haslam, and C.B. Harley. 1988. Molecular cloning and expression of the major protein kinase C substrate of platelets. Nature (Lond.). 333:470-473.
61. 1 cyclins: Cln3 may be an upstream activator of Cln1, Cln2 and other cyclins. EMBO (Eur. Mol. Biol. Organ.) J. 12:1955-1968.
62. Vojtek, A.B., S.M. Hollenberg, and J.A. Cooper. 1993. Mammalian Ras interacts directly with the serine/threonine kinase Raf. Cell. 74:205-214.
63. Zhao, Z.-S., T. Leung, E. Manser, and L. Lim. 1995. Pheromone signalling in Saccharomyces cerevisiae requires the small GTP-binding protein Cdc42p and its activator CDC24. Mol. Cell Biol. 15:5246-5257.
64. Zheng, Y., R. Cerione, and A. Bender. 1994. Control of the yeast bud-site assembly GTPase Cdc42: catalysis of guanine-nucleotide exchange by Cdc24 and stimulation of GTPase activity be Bem3. J. Biol. Chem. 269:2369-2372.
65. Ziman, M. and D.I. Johnson. 1994, Genetic evidence for a functional interaction between Saccharomyces cerevisiae CDC24 and CDC42. Yeast. 10:463-474.
66. Ziman, M., J.M. O'Brien, L.A. Ouellette, W.R. Church, and D.I. Johnson. 1991. Mutational analysis of CDC42Sc, a Saccharomyces cerevisiae gene that encodes a putative GTP-binding protein involved in the control of cell polarity. Mol. Cell Biol. 11:3537-3544.