-
1
-
-
84887123502
-
The alternative lengthening of telomere phenotype is significantly associated with loss of ATRX expression in high-grade pediatric and adult astrocytomas: a multi-institutional study of 214 astrocytomas
-
COI: 1:CAS:528:DC%2BC3sXhslartLnP, PID: 23765250
-
Abedalthagafi M, Phillips JJ, Kim GE et al (2013) The alternative lengthening of telomere phenotype is significantly associated with loss of ATRX expression in high-grade pediatric and adult astrocytomas: a multi-institutional study of 214 astrocytomas. Mod Pathol 26:1425–1432
-
(2013)
Mod Pathol
, vol.26
, pp. 1425-1432
-
-
Abedalthagafi, M.1
Phillips, J.J.2
Kim, G.E.3
-
2
-
-
57349166553
-
Hydroxyglutaric aciduria and malignant brain tumor: a case report and literature review
-
PID: 18931888
-
Aghili M, Zahedi F, Rafiee E (2009) Hydroxyglutaric aciduria and malignant brain tumor: a case report and literature review. J Neurooncol 91:233–236
-
(2009)
J Neurooncol
, vol.91
, pp. 233-236
-
-
Aghili, M.1
Zahedi, F.2
Rafiee, E.3
-
3
-
-
84864281784
-
No prognostic value of IDH1 mutations in a series of 100 WHO grade II astrocytomas
-
COI: 1:CAS:528:DC%2BC38XhtVOgsrnK, PID: 22528790
-
Ahmadi R, Stockhammer F, Becker N et al (2012) No prognostic value of IDH1 mutations in a series of 100 WHO grade II astrocytomas. J Neurooncol 109:15–22
-
(2012)
J Neurooncol
, vol.109
, pp. 15-22
-
-
Ahmadi, R.1
Stockhammer, F.2
Becker, N.3
-
4
-
-
84881095932
-
Upregulating mutations in the TERT promoter commonly occur in adult malignant gliomas and are strongly associated with total 1p19q loss
-
COI: 1:CAS:528:DC%2BC3sXht1eksL3L, PID: 23764841
-
Arita H, Narita Y, Fukushima S et al (2013) Upregulating mutations in the TERT promoter commonly occur in adult malignant gliomas and are strongly associated with total 1p19q loss. Acta Neuropathol 126:267–276
-
(2013)
Acta Neuropathol
, vol.126
, pp. 267-276
-
-
Arita, H.1
Narita, Y.2
Fukushima, S.3
-
5
-
-
84929703124
-
Development of a robust and sensitive pyrosequencing assay for the detection of IDH1/2 mutations in gliomas
-
COI: 1:CAS:528:DC%2BC2cXmvFCntbo%3D, PID: 24748374
-
Arita H, Narita Y, Matsushita Y et al (2015) Development of a robust and sensitive pyrosequencing assay for the detection of IDH1/2 mutations in gliomas. Brain Tumor Pathol 32:22–30
-
(2015)
Brain Tumor Pathol
, vol.32
, pp. 22-30
-
-
Arita, H.1
Narita, Y.2
Matsushita, Y.3
-
6
-
-
85018132399
-
IDH1/2 mutation detection in gliomas
-
Arita H, Narita Y, Yoshida A, Hashimoto N, Yoshimine T, Ichimura K (2014) IDH1/2 mutation detection in gliomas. Brain Tumor Pathol [Epub ahead of print]
-
(2014)
Brain Tumor Pathol [Epub ahead of print]
-
-
Arita, H.1
Narita, Y.2
Yoshida, A.3
Hashimoto, N.4
Yoshimine, T.5
Ichimura, K.6
-
7
-
-
0028287205
-
Assessment of the pathological grade of astrocytic gliomas using an MRI score
-
COI: 1:STN:280:DyaK2czksVCjsA%3D%3D, PID: 8065577
-
Asari S, Makabe T, Katayama S, Itoh T, Tsuchida S, Ohmoto T (1994) Assessment of the pathological grade of astrocytic gliomas using an MRI score. Neuroradiology 36:308–310
-
(1994)
Neuroradiology
, vol.36
, pp. 308-310
-
-
Asari, S.1
Makabe, T.2
Katayama, S.3
Itoh, T.4
Tsuchida, S.5
Ohmoto, T.6
-
8
-
-
71649094272
-
Adult supratentorial low-grade glioma: long-term experience at a single institution
-
PID: 19395201
-
Bauman G, Fisher B, Watling C, Cairncross JG, Macdonald D (2009) Adult supratentorial low-grade glioma: long-term experience at a single institution. Int J Radiat Oncol Biol Phys 75:1401–1407
-
(2009)
Int J Radiat Oncol Biol Phys
, vol.75
, pp. 1401-1407
-
-
Bauman, G.1
Fisher, B.2
Watling, C.3
Cairncross, J.G.4
Macdonald, D.5
-
9
-
-
84919924438
-
Specific detection of methionine 27 mutation in histone 3 variants (H3K27M) in fixed tissue from high-grade astrocytomas
-
COI: 1:CAS:528:DC%2BC2cXhsFGhu77I, PID: 25200321
-
Bechet D, Gielen GG, Korshunov A et al (2014) Specific detection of methionine 27 mutation in histone 3 variants (H3K27M) in fixed tissue from high-grade astrocytomas. Acta Neuropathol 128:733–741
-
(2014)
Acta Neuropathol
, vol.128
, pp. 733-741
-
-
Bechet, D.1
Gielen, G.G.2
Korshunov, A.3
-
10
-
-
77953019788
-
The prognostic IDH1(R132) mutation is associated with reduced NADP+-dependent IDH activity in glioblastoma
-
COI: 1:CAS:528:DC%2BC3cXjs1aju7Y%3D, PID: 20127344
-
Bleeker FE, Atai NA, Lamba S et al (2010) The prognostic IDH1(R132) mutation is associated with reduced NADP+-dependent IDH activity in glioblastoma. Acta Neuropathol 119:487–494
-
(2010)
Acta Neuropathol
, vol.119
, pp. 487-494
-
-
Bleeker, F.E.1
Atai, N.A.2
Lamba, S.3
-
11
-
-
0029397307
-
The p53 gene and its role in human brain tumors
-
COI: 1:STN:280:DyaK287lslGgtA%3D%3D, PID: 8586466
-
Bogler O, Huang HJ, Kleihues P, Cavenee WK (1995) The p53 gene and its role in human brain tumors. Glia 15:308–327
-
(1995)
Glia
, vol.15
, pp. 308-327
-
-
Bogler, O.1
Huang, H.J.2
Kleihues, P.3
Cavenee, W.K.4
-
12
-
-
78649585883
-
COLD PCR HRM: a highly sensitive detection method for IDH1 mutations
-
COI: 1:CAS:528:DC%2BC3MXis1Cguw%3D%3D, PID: 20886613
-
Boisselier B, Marie Y, Labussiere M et al (2010) COLD PCR HRM: a highly sensitive detection method for IDH1 mutations. Hum Mutat 31:1360–1365
-
(2010)
Hum Mutat
, vol.31
, pp. 1360-1365
-
-
Boisselier, B.1
Marie, Y.2
Labussiere, M.3
-
13
-
-
53949091844
-
Brain tumor epidemiology: consensus from the Brain Tumor Epidemiology Consortium
-
PID: 18798534
-
Bondy ML, Scheurer ME, Malmer B et al (2008) Brain tumor epidemiology: consensus from the Brain Tumor Epidemiology Consortium. Cancer 113:1953–1968
-
(2008)
Cancer
, vol.113
, pp. 1953-1968
-
-
Bondy, M.L.1
Scheurer, M.E.2
Malmer, B.3
-
14
-
-
84891860582
-
Cigarette smoking, alcohol intake, and risk of glioma in the NIH-AARP Diet and Health Study
-
COI: 1:STN:280:DC%2BC2c3mtlWrug%3D%3D, PID: 24335921
-
Braganza MZ, Rajaraman P, Park Y et al (2014) Cigarette smoking, alcohol intake, and risk of glioma in the NIH-AARP Diet and Health Study. Br J Cancer 110:242–248
-
(2014)
Br J Cancer
, vol.110
, pp. 242-248
-
-
Braganza, M.Z.1
Rajaraman, P.2
Park, Y.3
-
15
-
-
34047202235
-
Survival following adjuvant PCV or temozolomide for anaplastic astrocytoma
-
COI: 1:CAS:528:DC%2BD28Xot1agtLo%3D, PID: 16723632
-
Brandes AA, Nicolardi L, Tosoni A et al (2006) Survival following adjuvant PCV or temozolomide for anaplastic astrocytoma. Neuro Oncol 8:253–260
-
(2006)
Neuro Oncol
, vol.8
, pp. 253-260
-
-
Brandes, A.A.1
Nicolardi, L.2
Tosoni, A.3
-
16
-
-
84885074034
-
The somatic genomic landscape of glioblastoma
-
COI: 1:CAS:528:DC%2BC3sXhs1Srtb7J, PID: 24120142
-
Brennan CW, Verhaak RG, McKenna A et al (2013) The somatic genomic landscape of glioblastoma. Cell 155:462–477
-
(2013)
Cell
, vol.155
, pp. 462-477
-
-
Brennan, C.W.1
Verhaak, R.G.2
McKenna, A.3
-
17
-
-
0038352145
-
Effects of radiotherapy on cognitive function in patients with low-grade glioma measured by the folstein mini-mental state examination
-
PID: 12829670
-
Brown PD, Buckner JC, O’Fallon JR et al (2003) Effects of radiotherapy on cognitive function in patients with low-grade glioma measured by the folstein mini-mental state examination. J Clin Oncol 21:2519–2524
-
(2003)
J Clin Oncol
, vol.21
, pp. 2519-2524
-
-
Brown, P.D.1
Buckner, J.C.2
O’Fallon, J.R.3
-
18
-
-
84929705834
-
Report of Brain Tumor Registry of Japan (2001–2004) 13th edition
-
The Committee of Brain Tumor Registry of Japan
-
The Committee of Brain Tumor Registry of Japan (2014) Report of Brain Tumor Registry of Japan (2001–2004) 13th edition. Neurol Med Chir (Tokyo) 54:1–102
-
(2014)
Neurol Med Chir (Tokyo)
, vol.54
-
-
-
19
-
-
84907001958
-
Phase III study of radiation therapy (RT) with or without procarbazine, CCNU, and vincristine (PCV) in low-grade glioma: RTOG 9802 with Alliance, ECOG, and SWOG
-
Buckner JC, Pugh SL, Shaw EG et al (2014) Phase III study of radiation therapy (RT) with or without procarbazine, CCNU, and vincristine (PCV) in low-grade glioma: RTOG 9802 with Alliance, ECOG, and SWOG. J Clin Oncol 2014 ASCO Annu Meet Abstr 32:2000
-
(2014)
J Clin Oncol 2014 ASCO Annu Meet Abstr
, vol.32
, pp. 2000
-
-
Buckner, J.C.1
Pugh, S.L.2
Shaw, E.G.3
-
20
-
-
84919480160
-
Histopathological spectrum of paediatric diffuse intrinsic pontine glioma: diagnostic and therapeutic implications
-
COI: 1:CAS:528:DC%2BC2cXht1WhsLzJ, PID: 25047029
-
Buczkowicz P, Bartels U, Bouffet E, Becher O, Hawkins C (2014) Histopathological spectrum of paediatric diffuse intrinsic pontine glioma: diagnostic and therapeutic implications. Acta Neuropathol 128:573–581
-
(2014)
Acta Neuropathol
, vol.128
, pp. 573-581
-
-
Buczkowicz, P.1
Bartels, U.2
Bouffet, E.3
Becher, O.4
Hawkins, C.5
-
21
-
-
84873338121
-
Phase III trial of chemoradiotherapy for anaplastic oligodendroglioma: long-term results of RTOG 9402
-
COI: 1:CAS:528:DC%2BC3sXis1Cgtbk%3D, PID: 23071247
-
Cairncross G, Wang M, Shaw E et al (2013) Phase III trial of chemoradiotherapy for anaplastic oligodendroglioma: long-term results of RTOG 9402. J Clin Oncol 31:337–343
-
(2013)
J Clin Oncol
, vol.31
, pp. 337-343
-
-
Cairncross, G.1
Wang, M.2
Shaw, E.3
-
22
-
-
54149085908
-
The interface between glial progenitors and gliomas
-
PID: 18784926
-
Canoll P, Goldman JE (2008) The interface between glial progenitors and gliomas. Acta Neuropathol 116:465–477
-
(2008)
Acta Neuropathol
, vol.116
, pp. 465-477
-
-
Canoll, P.1
Goldman, J.E.2
-
23
-
-
77955142776
-
Application of mutant IDH1 antibody to differentiate diffuse glioma from nonneoplastic central nervous system lesions and therapy-induced changes
-
PID: 20661018
-
Capper D, Sahm F, Hartmann C, Meyermann R, von Deimling A, Schittenhelm J (2010) Application of mutant IDH1 antibody to differentiate diffuse glioma from nonneoplastic central nervous system lesions and therapy-induced changes. Am J Surg Pathol 34:1199–1204
-
(2010)
Am J Surg Pathol
, vol.34
, pp. 1199-1204
-
-
Capper, D.1
Sahm, F.2
Hartmann, C.3
Meyermann, R.4
von Deimling, A.5
Schittenhelm, J.6
-
24
-
-
70449518400
-
Monoclonal antibody specific for IDH1 R132H mutation
-
COI: 1:CAS:528:DC%2BD1MXhtlKitLrK, PID: 19798509
-
Capper D, Zentgraf H, Balss J, Hartmann C, von Deimling A (2009) Monoclonal antibody specific for IDH1 R132H mutation. Acta Neuropathol 118:599–601
-
(2009)
Acta Neuropathol
, vol.118
, pp. 599-601
-
-
Capper, D.1
Zentgraf, H.2
Balss, J.3
Hartmann, C.4
von Deimling, A.5
-
25
-
-
84866002291
-
The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data
-
PID: 22588877
-
Cerami E, Gao J, Dogrusoz U et al (2012) The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data. Cancer Discov 2:401–404
-
(2012)
Cancer Discov
, vol.2
, pp. 401-404
-
-
Cerami, E.1
Gao, J.2
Dogrusoz, U.3
-
26
-
-
75749112226
-
Recurrence and malignant degeneration after resection of adult hemispheric low-grade gliomas
-
PID: 19361270
-
Chaichana KL, McGirt MJ, Laterra J, Olivi A, Quinones-Hinojosa A (2010) Recurrence and malignant degeneration after resection of adult hemispheric low-grade gliomas. J Neurosurg 112:10–17
-
(2010)
J Neurosurg
, vol.112
, pp. 10-17
-
-
Chaichana, K.L.1
McGirt, M.J.2
Laterra, J.3
Olivi, A.4
Quinones-Hinojosa, A.5
-
27
-
-
84858248558
-
Association of age at diagnosis and genetic mutations in patients with neuroblastoma
-
COI: 1:CAS:528:DC%2BC38XksFCisL8%3D, PID: 22416102
-
Cheung NK, Zhang J, Lu C et al (2012) Association of age at diagnosis and genetic mutations in patients with neuroblastoma. JAMA 307:1062–1071
-
(2012)
JAMA
, vol.307
, pp. 1062-1071
-
-
Cheung, N.K.1
Zhang, J.2
Lu, C.3
-
28
-
-
84880725971
-
Alternative lengthening of telomeres: remodeling the telomere architecture
-
PID: 23429284
-
Conomos D, Pickett HA, Reddel RR (2013) Alternative lengthening of telomeres: remodeling the telomere architecture. Front Oncol 3:27
-
(2013)
Front Oncol
, vol.3
, pp. 27
-
-
Conomos, D.1
Pickett, H.A.2
Reddel, R.R.3
-
29
-
-
0034019630
-
Compartmentation of brain glutamate metabolism in neurons and glia
-
COI: 1:CAS:528:DC%2BD3cXit1ehsrw%3D, PID: 10736375
-
Daikhin Y, Yudkoff M (2000) Compartmentation of brain glutamate metabolism in neurons and glia. J Nutr 130:1026S–1031S
-
(2000)
J Nutr
, vol.130
, pp. 1026-1031
-
-
Daikhin, Y.1
Yudkoff, M.2
-
30
-
-
72049125350
-
Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
-
COI: 1:CAS:528:DC%2BD1MXhsVGlurzE, PID: 19935646
-
Dang L, White DW, Gross S et al (2009) Cancer-associated IDH1 mutations produce 2-hydroxyglutarate. Nature 462:739–744
-
(2009)
Nature
, vol.462
, pp. 739-744
-
-
Dang, L.1
White, D.W.2
Gross, S.3
-
31
-
-
79251469441
-
A 4-gene signature associated with clinical outcome in high-grade gliomas
-
PID: 21224364
-
de Tayrac M, Aubry M, Saikali S et al (2011) A 4-gene signature associated with clinical outcome in high-grade gliomas. Clin Cancer Res 17:317–327
-
(2011)
Clin Cancer Res
, vol.17
, pp. 317-327
-
-
de Tayrac, M.1
Aubry, M.2
Saikali, S.3
-
32
-
-
73349108806
-
IDH1 mutations in low-grade astrocytomas predict survival but not response to temozolomide
-
COI: 1:CAS:528:DC%2BD1MXhsVaks77K, PID: 19933982
-
Dubbink HJ, Taal W, van Marion R et al (2009) IDH1 mutations in low-grade astrocytomas predict survival but not response to temozolomide. Neurology 73:1792–1795
-
(2009)
Neurology
, vol.73
, pp. 1792-1795
-
-
Dubbink, H.J.1
Taal, W.2
van Marion, R.3
-
33
-
-
77953028158
-
Rapid and sensitive assessment of the IDH1 and IDH2 mutation status in cerebral gliomas based on DNA pyrosequencing
-
COI: 1:CAS:528:DC%2BC3cXjs1aisr8%3D, PID: 20131059
-
Felsberg J, Wolter M, Seul H et al (2010) Rapid and sensitive assessment of the IDH1 and IDH2 mutation status in cerebral gliomas based on DNA pyrosequencing. Acta Neuropathol 119:501–507
-
(2010)
Acta Neuropathol
, vol.119
, pp. 501-507
-
-
Felsberg, J.1
Wolter, M.2
Seul, H.3
-
34
-
-
78650019179
-
Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation
-
COI: 1:CAS:528:DC%2BC3cXhsFGhsbvJ, PID: 21130701
-
Figueroa ME, Abdel-Wahab O, Lu C et al (2010) Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation. Cancer Cell 18:553–567
-
(2010)
Cancer Cell
, vol.18
, pp. 553-567
-
-
Figueroa, M.E.1
Abdel-Wahab, O.2
Lu, C.3
-
35
-
-
84916627726
-
A phase II study of a temozolomide-based chemoradiotherapy regimen for high-risk low-grade gliomas: preliminary results of RTOG 0424
-
Fisher BJ, Lui J, Macdonald DR et al (2013) A phase II study of a temozolomide-based chemoradiotherapy regimen for high-risk low-grade gliomas: preliminary results of RTOG 0424. J Clin Oncol 31:abstract 2008
-
(2013)
J Clin Oncol 31:abstract
, pp. 2008
-
-
Fisher, B.J.1
Lui, J.2
Macdonald, D.R.3
-
36
-
-
84875740314
-
Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal
-
Gao J, Aksoy BA, Dogrusoz U et al (2013) Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal. Sci Signal 6:pl1
-
(2013)
Sci Signal 6:pl1
-
-
Gao, J.1
Aksoy, B.A.2
Dogrusoz, U.3
-
37
-
-
33847398443
-
Alpha thalassaemia-mental retardation, X linked
-
PID: 16722615
-
Gibbons R (2006) Alpha thalassaemia-mental retardation, X linked. Orphanet J Rare Dis 1:15
-
(2006)
Orphanet J Rare Dis
, vol.1
, pp. 15
-
-
Gibbons, R.1
-
38
-
-
0028939603
-
Mutations in a putative global transcriptional regulator cause X-linked mental retardation with alpha-thalassemia (ATR-X syndrome)
-
COI: 1:CAS:528:DyaK2MXkslOmtbw%3D, PID: 7697714
-
Gibbons RJ, Picketts DJ, Villard L, Higgs DR (1995) Mutations in a putative global transcriptional regulator cause X-linked mental retardation with alpha-thalassemia (ATR-X syndrome). Cell 80:837–845
-
(1995)
Cell
, vol.80
, pp. 837-845
-
-
Gibbons, R.J.1
Picketts, D.J.2
Villard, L.3
Higgs, D.R.4
-
39
-
-
84901603735
-
TP53 and p53 statuses and their clinical impact in diffuse low grade gliomas
-
COI: 1:CAS:528:DC%2BC2cXjslKqsbk%3D, PID: 24590827
-
Gillet E, Alentorn A, Doukoure B et al (2014) TP53 and p53 statuses and their clinical impact in diffuse low grade gliomas. J Neurooncol 118:131–139
-
(2014)
J Neurooncol
, vol.118
, pp. 131-139
-
-
Gillet, E.1
Alentorn, A.2
Doukoure, B.3
-
40
-
-
84897475322
-
Molecular subtypes of glioblastoma are relevant to lower grade glioma
-
PID: 24614622
-
Guan X, Vengoechea J, Zheng S et al (2014) Molecular subtypes of glioblastoma are relevant to lower grade glioma. PLoS One 9:e91216
-
(2014)
PLoS One
, vol.9
, pp. 91216
-
-
Guan, X.1
Vengoechea, J.2
Zheng, S.3
-
41
-
-
84877025889
-
Expanding the spectrum of IDH1 mutations in gliomas
-
COI: 1:CAS:528:DC%2BC3sXntF2is7c%3D, PID: 23307057
-
Gupta R, Flanagan S, Li CC et al (2013) Expanding the spectrum of IDH1 mutations in gliomas. Mod Pathol 26:619–625
-
(2013)
Mod Pathol
, vol.26
, pp. 619-625
-
-
Gupta, R.1
Flanagan, S.2
Li, C.C.3
-
42
-
-
79952284127
-
Hallmarks of cancer: the next generation
-
COI: 1:CAS:528:DC%2BC3MXjsFeqtrk%3D, PID: 21376230
-
Hanahan D, Weinberg RA (2011) Hallmarks of cancer: the next generation. Cell 144:646–674
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
43
-
-
79960315686
-
Molecular markers in low-grade gliomas: predictive or prognostic?
-
COI: 1:CAS:528:DC%2BC3MXos1Smur4%3D, PID: 21558404
-
Hartmann C, Hentschel B, Tatagiba M et al (2011) Molecular markers in low-grade gliomas: predictive or prognostic? Clin Cancer Res 17:4588–4599
-
(2011)
Clin Cancer Res
, vol.17
, pp. 4588-4599
-
-
Hartmann, C.1
Hentschel, B.2
Tatagiba, M.3
-
44
-
-
78651082266
-
Patients with IDH1 wild type anaplastic astrocytomas exhibit worse prognosis than IDH1-mutated glioblastomas, and IDH1 mutation status accounts for the unfavorable prognostic effect of higher age: implications for classification of gliomas
-
PID: 21088844
-
Hartmann C, Hentschel B, Wick W et al (2010) Patients with IDH1 wild type anaplastic astrocytomas exhibit worse prognosis than IDH1-mutated glioblastomas, and IDH1 mutation status accounts for the unfavorable prognostic effect of higher age: implications for classification of gliomas. Acta Neuropathol 120:707–718
-
(2010)
Acta Neuropathol
, vol.120
, pp. 707-718
-
-
Hartmann, C.1
Hentschel, B.2
Wick, W.3
-
45
-
-
69949114447
-
Type and frequency of IDH1 and IDH2 mutations are related to astrocytic and oligodendroglial differentiation and age: a study of 1,010 diffuse gliomas
-
PID: 19554337
-
Hartmann C, Meyer J, Balss J et al (2009) Type and frequency of IDH1 and IDH2 mutations are related to astrocytic and oligodendroglial differentiation and age: a study of 1,010 diffuse gliomas. Acta Neuropathol 118:469–474
-
(2009)
Acta Neuropathol
, vol.118
, pp. 469-474
-
-
Hartmann, C.1
Meyer, J.2
Balss, J.3
-
46
-
-
79960700556
-
Altered telomeres in tumors with ATRX and DAXX mutations
-
COI: 1:CAS:528:DC%2BC3MXovF2mtb8%3D, PID: 21719641
-
Heaphy CM, de Wilde RF, Jiao Y et al (2011) Altered telomeres in tumors with ATRX and DAXX mutations. Science 333:425
-
(2011)
Science
, vol.333
, pp. 425
-
-
Heaphy, C.M.1
de Wilde, R.F.2
Jiao, Y.3
-
47
-
-
84886707494
-
What do we know about IDH1/2 mutations so far, and how do we use it?
-
COI: 1:CAS:528:DC%2BC3sXmsFeltLc%3D, PID: 23512379
-
Horbinski C (2013) What do we know about IDH1/2 mutations so far, and how do we use it? Acta Neuropathol 125:621–636
-
(2013)
Acta Neuropathol
, vol.125
, pp. 621-636
-
-
Horbinski, C.1
-
48
-
-
77954357852
-
Detection of IDH1 and IDH2 mutations by fluorescence melting curve analysis as a diagnostic tool for brain biopsies
-
COI: 1:CAS:528:DC%2BC3cXhtVehurrF, PID: 20431032
-
Horbinski C, Kelly L, Nikiforov YE, Durso MB, Nikiforova MN (2010) Detection of IDH1 and IDH2 mutations by fluorescence melting curve analysis as a diagnostic tool for brain biopsies. J Mol Diagn 12:487–492
-
(2010)
J Mol Diagn
, vol.12
, pp. 487-492
-
-
Horbinski, C.1
Kelly, L.2
Nikiforov, Y.E.3
Durso, M.B.4
Nikiforova, M.N.5
-
49
-
-
84874191269
-
TERT promoter mutations in familial and sporadic melanoma
-
COI: 1:CAS:528:DC%2BC3sXis1Oisbs%3D, PID: 23348503
-
Horn S, Figl A, Rachakonda PS et al (2013) TERT promoter mutations in familial and sporadic melanoma. Science 339:959–961
-
(2013)
Science
, vol.339
, pp. 959-961
-
-
Horn, S.1
Figl, A.2
Rachakonda, P.S.3
-
50
-
-
78149249554
-
IDH1 or IDH2 mutations predict longer survival and response to temozolomide in low-grade gliomas
-
COI: 1:CAS:528:DC%2BC3cXhtlGmtrjK, PID: 20975057
-
Houillier C, Wang X, Kaloshi G et al (2010) IDH1 or IDH2 mutations predict longer survival and response to temozolomide in low-grade gliomas. Neurology 75:1560–1566
-
(2010)
Neurology
, vol.75
, pp. 1560-1566
-
-
Houillier, C.1
Wang, X.2
Kaloshi, G.3
-
51
-
-
84874189784
-
Highly recurrent TERT promoter mutations in human melanoma
-
COI: 1:CAS:528:DC%2BC3sXis1Oisbo%3D, PID: 23348506
-
Huang FW, Hodis E, Xu MJ, Kryukov GV, Chin L, Garraway LA (2013) Highly recurrent TERT promoter mutations in human melanoma. Science 339:957–959
-
(2013)
Science
, vol.339
, pp. 957-959
-
-
Huang, F.W.1
Hodis, E.2
Xu, M.J.3
Kryukov, G.V.4
Chin, L.5
Garraway, L.A.6
-
52
-
-
84885049499
-
The CpG island methylator phenotype: what’s in a name?
-
COI: 1:CAS:528:DC%2BC3sXhsFGrsrrI, PID: 23801749
-
Hughes LA, Melotte V, de Schrijver J et al (2013) The CpG island methylator phenotype: what’s in a name? Cancer Res 73:5858–5868
-
(2013)
Cancer Res
, vol.73
, pp. 5858-5868
-
-
Hughes, L.A.1
Melotte, V.2
de Schrijver, J.3
-
53
-
-
68349116524
-
IDH1 mutations are present in the majority of common adult gliomas but rare in primary glioblastomas
-
COI: 1:CAS:528:DC%2BD1MXhtV2qur%2FF, PID: 19435942
-
Ichimura K, Pearson DM, Kocialkowski S et al (2009) IDH1 mutations are present in the majority of common adult gliomas but rare in primary glioblastomas. Neuro Oncol 11:341–347
-
(2009)
Neuro Oncol
, vol.11
, pp. 341-347
-
-
Ichimura, K.1
Pearson, D.M.2
Kocialkowski, S.3
-
54
-
-
84892377126
-
Comparison of high resolution melting analysis, pyrosequencing, next generation sequencing and immunohistochemistry to conventional Sanger sequencing for the detection of p. V600E and non-p.V600E BRAF mutations
-
PID: 24410877
-
Ihle MA, Fassunke J, Konig K et al (2014) Comparison of high resolution melting analysis, pyrosequencing, next generation sequencing and immunohistochemistry to conventional Sanger sequencing for the detection of p. V600E and non-p.V600E BRAF mutations. BMC Cancer 14:13
-
(2014)
BMC Cancer
, vol.14
, pp. 13
-
-
Ihle, M.A.1
Fassunke, J.2
Konig, K.3
-
55
-
-
80052752036
-
Transformation of low grade glioma and correlation with outcome: an NCCTG database analysis
-
COI: 1:STN:280:DC%2BC3MjktVegug%3D%3D, PID: 21153680
-
Jaeckle KA, Decker PA, Ballman KV et al (2011) Transformation of low grade glioma and correlation with outcome: an NCCTG database analysis. J Neurooncol 104:253–259
-
(2011)
J Neurooncol
, vol.104
, pp. 253-259
-
-
Jaeckle, K.A.1
Decker, P.A.2
Ballman, K.V.3
-
56
-
-
84868667212
-
Comparison of a strategy favoring early surgical resection vs a strategy favoring watchful waiting in low-grade gliomas
-
Jakola AS, Myrmel KS, Kloster R et al (2012) Comparison of a strategy favoring early surgical resection vs a strategy favoring watchful waiting in low-grade gliomas. JAMA 308:1–8
-
(2012)
JAMA
, vol.308
-
-
Jakola, A.S.1
Myrmel, K.S.2
Kloster, R.3
-
57
-
-
0010645263
-
Mitotic recombination of chromosome 17 in astrocytomas
-
COI: 1:STN:280:DyaL1M3gt1Chtw%3D%3D, PID: 2565039
-
James CD, Carlbom E, Nordenskjold M, Collins VP, Cavenee WK (1989) Mitotic recombination of chromosome 17 in astrocytomas. Proc Natl Acad Sci USA 86:2858–2862
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 2858-2862
-
-
James, C.D.1
Carlbom, E.2
Nordenskjold, M.3
Collins, V.P.4
Cavenee, W.K.5
-
58
-
-
84868625787
-
Frequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomas
-
PID: 22869205
-
Jiao Y, Killela PJ, Reitman ZJ et al (2012) Frequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomas. Oncotarget 3:709–722
-
(2012)
Oncotarget
, vol.3
, pp. 709-722
-
-
Jiao, Y.1
Killela, P.J.2
Reitman, Z.J.3
-
59
-
-
79952279828
-
DAXX/ATRX, MEN1, and mTOR pathway genes are frequently altered in pancreatic neuroendocrine tumors
-
COI: 1:CAS:528:DC%2BC3MXislOku70%3D, PID: 21252315
-
Jiao Y, Shi C, Edil BH et al (2011) DAXX/ATRX, MEN1, and mTOR pathway genes are frequently altered in pancreatic neuroendocrine tumors. Science 331:1199–1203
-
(2011)
Science
, vol.331
, pp. 1199-1203
-
-
Jiao, Y.1
Shi, C.2
Edil, B.H.3
-
60
-
-
84892373020
-
Mutational analysis reveals the origin and therapy-driven evolution of recurrent glioma
-
COI: 1:CAS:528:DC%2BC2cXktVyktQ%3D%3D, PID: 24336570
-
Johnson BE, Mazor T, Hong C et al (2014) Mutational analysis reveals the origin and therapy-driven evolution of recurrent glioma. Science 343:189–193
-
(2014)
Science
, vol.343
, pp. 189-193
-
-
Johnson, B.E.1
Mazor, T.2
Hong, C.3
-
61
-
-
84872788316
-
Whole-exome sequencing identifies ATRX mutation as a key molecular determinant in lower-grade glioma
-
PID: 23104868
-
Kannan K, Inagaki A, Silber J et al (2012) Whole-exome sequencing identifies ATRX mutation as a key molecular determinant in lower-grade glioma. Oncotarget 3:1194–1203
-
(2012)
Oncotarget
, vol.3
, pp. 1194-1203
-
-
Kannan, K.1
Inagaki, A.2
Silber, J.3
-
62
-
-
10544231454
-
A randomized trial on dose-response in radiation therapy of low-grade cerebral glioma: European Organization for Research and Treatment of Cancer (EORTC) Study 22844
-
COI: 1:STN:280:DyaK2s7gsVWrsg%3D%3D, PID: 8948338
-
Karim AB, Maat B, Hatlevoll R et al (1996) A randomized trial on dose-response in radiation therapy of low-grade cerebral glioma: European Organization for Research and Treatment of Cancer (EORTC) Study 22844. Int J Radiat Oncol Biol Phys 36:549–556
-
(1996)
Int J Radiat Oncol Biol Phys
, vol.36
, pp. 549-556
-
-
Karim, A.B.1
Maat, B.2
Hatlevoll, R.3
-
63
-
-
84921423035
-
Specific monoclonal antibodies against IDH1/2 mutations as diagnostic tools for gliomas
-
COI: 1:CAS:528:DC%2BC2cXhvVWnurrL, PID: 25324168
-
Kato Y (2015) Specific monoclonal antibodies against IDH1/2 mutations as diagnostic tools for gliomas. Brain Tumor Pathol 32:3–11
-
(2015)
Brain Tumor Pathol
, vol.32
, pp. 3-11
-
-
Kato, Y.1
-
64
-
-
70449708940
-
A monoclonal antibody IMab-1 specifically recognizes IDH1R132H, the most common glioma-derived mutation
-
COI: 1:CAS:528:DC%2BD1MXhsVKgtLfO, PID: 19818334
-
Kato Y, Jin G, Kuan CT, McLendon RE, Yan H, Bigner DD (2009) A monoclonal antibody IMab-1 specifically recognizes IDH1R132H, the most common glioma-derived mutation. Biochem Biophys Res Commun 390:547–551
-
(2009)
Biochem Biophys Res Commun
, vol.390
, pp. 547-551
-
-
Kato, Y.1
Jin, G.2
Kuan, C.T.3
McLendon, R.E.4
Yan, H.5
Bigner, D.D.6
-
65
-
-
84865863019
-
K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas
-
COI: 1:CAS:528:DC%2BC38Xht1egt7vP, PID: 22661320
-
Khuong-Quang DA, Buczkowicz P, Rakopoulos P et al (2012) K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas. Acta Neuropathol 124:439–447
-
(2012)
Acta Neuropathol
, vol.124
, pp. 439-447
-
-
Khuong-Quang, D.A.1
Buczkowicz, P.2
Rakopoulos, P.3
-
66
-
-
84904247565
-
Mutations in IDH1, IDH2, and in the TERT promoter define clinically distinct subgroups of adult malignant gliomas
-
PID: 24722048
-
Killela PJ, Pirozzi CJ, Healy P et al (2014) Mutations in IDH1, IDH2, and in the TERT promoter define clinically distinct subgroups of adult malignant gliomas. Oncotarget 5:1515–1525
-
(2014)
Oncotarget
, vol.5
, pp. 1515-1525
-
-
Killela, P.J.1
Pirozzi, C.J.2
Healy, P.3
-
67
-
-
84904253732
-
The genetic landscape of anaplastic astrocytoma
-
PID: 24140581
-
Killela PJ, Pirozzi CJ, Reitman ZJ et al (2014) The genetic landscape of anaplastic astrocytoma. Oncotarget 5:1452–1457
-
(2014)
Oncotarget
, vol.5
, pp. 1452-1457
-
-
Killela, P.J.1
Pirozzi, C.J.2
Reitman, Z.J.3
-
68
-
-
84876067164
-
TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal
-
COI: 1:CAS:528:DC%2BC3sXnsFKksbc%3D, PID: 23530248
-
Killela PJ, Reitman ZJ, Jiao Y et al (2013) TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal. Proc Natl Acad Sci USA 110:6021–6026
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 6021-6026
-
-
Killela, P.J.1
Reitman, Z.J.2
Jiao, Y.3
-
69
-
-
0037361534
-
Cellular defense against singlet oxygen-induced oxidative damage by cytosolic NADP+-dependent isocitrate dehydrogenase
-
COI: 1:CAS:528:DC%2BD3sXhtFKht74%3D, PID: 12688426
-
Kim SY, Park JW (2003) Cellular defense against singlet oxygen-induced oxidative damage by cytosolic NADP+-dependent isocitrate dehydrogenase. Free Radic Res 37:309–316
-
(2003)
Free Radic Res
, vol.37
, pp. 309-316
-
-
Kim, S.Y.1
Park, J.W.2
-
70
-
-
78650226575
-
Molecular classification of low-grade diffuse gliomas
-
PID: 21075857
-
Kim YH, Nobusawa S, Mittelbronn M et al (2010) Molecular classification of low-grade diffuse gliomas. Am J Pathol 177:2708–2714
-
(2010)
Am J Pathol
, vol.177
, pp. 2708-2714
-
-
Kim, Y.H.1
Nobusawa, S.2
Mittelbronn, M.3
-
71
-
-
84911991931
-
The impact of concurrent temozolomide with adjuvant radiation and IDH mutation status among patients with anaplastic astrocytoma
-
COI: 1:CAS:528:DC%2BC2cXhtFSgurnK, PID: 24993250
-
Kizilbash SH, Giannini C, Voss JS et al (2014) The impact of concurrent temozolomide with adjuvant radiation and IDH mutation status among patients with anaplastic astrocytoma. J Neurooncol 120:85–93
-
(2014)
J Neurooncol
, vol.120
, pp. 85-93
-
-
Kizilbash, S.H.1
Giannini, C.2
Voss, J.S.3
-
72
-
-
84892590846
-
Distribution of TERT promoter mutations in pediatric and adult tumors of the nervous system
-
COI: 1:CAS:528:DC%2BC3sXhs1yqs7vM, PID: 24154961
-
Koelsche C, Sahm F, Capper D et al (2013) Distribution of TERT promoter mutations in pediatric and adult tumors of the nervous system. Acta Neuropathol 126:907–915
-
(2013)
Acta Neuropathol
, vol.126
, pp. 907-915
-
-
Koelsche, C.1
Sahm, F.2
Capper, D.3
-
73
-
-
77957948775
-
IDH2 mutations in patients with d-2-hydroxyglutaric aciduria
-
COI: 1:CAS:528:DC%2BC3cXht1Ois7fK, PID: 20847235
-
Kranendijk M, Struys EA, van Schaftingen E et al (2010) IDH2 mutations in patients with d-2-hydroxyglutaric aciduria. Science 330:336
-
(2010)
Science
, vol.330
, pp. 336
-
-
Kranendijk, M.1
Struys, E.A.2
van Schaftingen, E.3
-
74
-
-
0036614971
-
Cytosolic NADP(+)-dependent isocitrate dehydrogenase status modulates oxidative damage to cells
-
COI: 1:CAS:528:DC%2BD38XjvVehu7g%3D, PID: 12031902
-
Lee SM, Koh HJ, Park DC, Song BJ, Huh TL, Park JW (2002) Cytosolic NADP(+)-dependent isocitrate dehydrogenase status modulates oxidative damage to cells. Free Radic Biol Med 32:1185–1196
-
(2002)
Free Radic Biol Med
, vol.32
, pp. 1185-1196
-
-
Lee, S.M.1
Koh, H.J.2
Park, D.C.3
Song, B.J.4
Huh, T.L.5
Park, J.W.6
-
75
-
-
77956282773
-
Daxx is an H3.3-specific histone chaperone and cooperates with ATRX in replication-independent chromatin assembly at telomeres
-
COI: 1:CAS:528:DC%2BC3cXhtVCktrfO, PID: 20651253
-
Lewis PW, Elsaesser SJ, Noh KM, Stadler SC, Allis CD (2010) Daxx is an H3.3-specific histone chaperone and cooperates with ATRX in replication-independent chromatin assembly at telomeres. Proc Natl Acad Sci USA 107:14075–14080
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 14075-14080
-
-
Lewis, P.W.1
Elsaesser, S.J.2
Noh, K.M.3
Stadler, S.C.4
Allis, C.D.5
-
76
-
-
84877785024
-
Inhibition of PRC2 activity by a gain-of-function H3 mutation found in pediatric glioblastoma
-
COI: 1:CAS:528:DC%2BC3sXnsFSms7k%3D, PID: 23539183
-
Lewis PW, Muller MM, Koletsky MS et al (2013) Inhibition of PRC2 activity by a gain-of-function H3 mutation found in pediatric glioblastoma. Science 340:857–861
-
(2013)
Science
, vol.340
, pp. 857-861
-
-
Lewis, P.W.1
Muller, M.M.2
Koletsky, M.S.3
-
77
-
-
84908317863
-
Oncogenic signaling is dominant to cell of origin and dictates astrocytic or oligodendroglial tumor development from oligodendrocyte precursor cells
-
PID: 25355217
-
Lindberg N, Jiang Y, Xie Y et al (2014) Oncogenic signaling is dominant to cell of origin and dictates astrocytic or oligodendroglial tumor development from oligodendrocyte precursor cells. J Neurosci 34:14644–14651
-
(2014)
J Neurosci
, vol.34
, pp. 14644-14651
-
-
Lindberg, N.1
Jiang, Y.2
Xie, Y.3
-
78
-
-
84871020024
-
Frequent ATRX mutations and loss of expression in adult diffuse astrocytic tumors carrying IDH1/IDH2 and TP53 mutations
-
COI: 1:CAS:528:DC%2BC38XhsFags7vL, PID: 22886134
-
Liu XY, Gerges N, Korshunov A et al (2012) Frequent ATRX mutations and loss of expression in adult diffuse astrocytic tumors carrying IDH1/IDH2 and TP53 mutations. Acta Neuropathol 124:615–625
-
(2012)
Acta Neuropathol
, vol.124
, pp. 615-625
-
-
Liu, X.Y.1
Gerges, N.2
Korshunov, A.3
-
79
-
-
34347207046
-
-
International agency for research on cancer, Lyon
-
Louis DN, Ohgaki H, Wiestler OD, Cavenee WK (2007) WHO classification of tumours of the central nervous system, 4th edn. International agency for research on cancer, Lyon
-
(2007)
WHO classification of tumours of the central nervous system
-
-
Louis, D.N.1
Ohgaki, H.2
Wiestler, O.D.3
Cavenee, W.K.4
-
80
-
-
85027948565
-
International society of neuropathology-haarlem consensus guidelines, for nervous system tumor classification and grading
-
Louis DN, Perry A, Burger P et al (2014) International society of neuropathology-haarlem consensus guidelines, for nervous system tumor classification and grading. Brain Pathol
-
(2014)
Bra
-
-
Louis, D.N.1
Perry, A.2
Burger, P.3
-
81
-
-
84864619205
-
Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway
-
COI: 1:CAS:528:DC%2BC38XhtFSksbrK, PID: 22829774
-
Lovejoy CA, Li W, Reisenweber S et al (2012) Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway. PLoS Genet 8:e1002772
-
(2012)
PLoS Genet
, vol.8
, pp. 1002772
-
-
Lovejoy, C.A.1
Li, W.2
Reisenweber, S.3
-
82
-
-
84858796262
-
IDH mutation impairs histone demethylation and results in a block to cell differentiation
-
COI: 1:CAS:528:DC%2BC38XisVKks74%3D, PID: 22343901
-
Lu C, Ward PS, Kapoor GS et al (2012) IDH mutation impairs histone demethylation and results in a block to cell differentiation. Nature 483:474–478
-
(2012)
Nature
, vol.483
, pp. 474-478
-
-
Lu, C.1
Ward, P.S.2
Kapoor, G.S.3
-
83
-
-
84859553853
-
An in vivo patient-derived model of endogenous IDH1-mutant glioma
-
COI: 1:CAS:528:DC%2BC38Xhtl2hs7vI, PID: 22166263
-
Luchman HA, Stechishin OD, Dang NH et al (2012) An in vivo patient-derived model of endogenous IDH1-mutant glioma. Neuro Oncol 14:184–191
-
(2012)
Neuro Oncol
, vol.14
, pp. 184-191
-
-
Luchman, H.A.1
Stechishin, O.D.2
Dang, N.H.3
-
84
-
-
84919917043
-
Alternative lengthening of telomeres is enriched in, and impacts survival of TP53 mutant pediatric malignant brain tumors
-
COI: 1:CAS:528:DC%2BC2cXhslOgurvI, PID: 25315281
-
Mangerel J, Price A, Castelo-Branco P et al (2014) Alternative lengthening of telomeres is enriched in, and impacts survival of TP53 mutant pediatric malignant brain tumors. Acta Neuropathol 128:853–862
-
(2014)
Acta Neuropathol
, vol.128
, pp. 853-862
-
-
Mangerel, J.1
Price, A.2
Castelo-Branco, P.3
-
85
-
-
77952536841
-
IDH1 and IDH2 gene mutations identify novel molecular subsets within de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study
-
COI: 1:CAS:528:DC%2BC3cXnsFOntr0%3D, PID: 20368543
-
Marcucci G, Maharry K, Wu YZ et al (2010) IDH1 and IDH2 gene mutations identify novel molecular subsets within de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study. J Clin Oncol 28:2348–2355
-
(2010)
J Clin Oncol
, vol.28
, pp. 2348-2355
-
-
Marcucci, G.1
Maharry, K.2
Wu, Y.Z.3
-
86
-
-
77953873521
-
Post-contrast enhancement as a clinical indicator of prognosis in patients with anaplastic astrocytoma
-
PID: 20605464
-
Matar E, Cook RJ, Fowler AR et al (2010) Post-contrast enhancement as a clinical indicator of prognosis in patients with anaplastic astrocytoma. J Clin Neurosci 17:993–996
-
(2010)
J Clin Neurosci
, vol.17
, pp. 993-996
-
-
Matar, E.1
Cook, R.J.2
Fowler, A.R.3
-
87
-
-
78651067051
-
Absence of IDH mutation identifies a novel radiologic and molecular subtype of WHO grade II gliomas with dismal prognosis
-
PID: 21080178
-
Metellus P, Coulibaly B, Colin C et al (2010) Absence of IDH mutation identifies a novel radiologic and molecular subtype of WHO grade II gliomas with dismal prognosis. Acta Neuropathol 120:719–729
-
(2010)
Acta Neuropathol
, vol.120
, pp. 719-729
-
-
Metellus, P.1
Coulibaly, B.2
Colin, C.3
-
88
-
-
84927553853
-
BRAF mutation and CDKN2A deletion define a clinically distinct subgroup of childhood secondary high-grade glioma
-
COI: 1:CAS:528:DC%2BC2MXntVWltLg%3D, PID: 25667294
-
Mistry M, Zhukova N, Merico D et al (2015) BRAF mutation and CDKN2A deletion define a clinically distinct subgroup of childhood secondary high-grade glioma. J Clin Oncol 33:1015–1022
-
(2015)
J Clin Oncol
, vol.33
, pp. 1015-1022
-
-
Mistry, M.1
Zhukova, N.2
Merico, D.3
-
89
-
-
0035863293
-
Randomized trial of procarbazine, lomustine, and vincristine in the adjuvant treatment of high-grade astrocytoma: a medical research council trial
-
MRC TMRCBTWP
-
MRC TMRCBTWP (2001) Randomized trial of procarbazine, lomustine, and vincristine in the adjuvant treatment of high-grade astrocytoma: a medical research council trial. J Clin Oncol 19:509–518
-
(2001)
J Clin Oncol
, vol.19
, pp. 509-518
-
-
-
90
-
-
84859712831
-
Significance of IDH mutations varies with tumor histology, grade, and genetics in Japanese glioma patients
-
COI: 1:CAS:528:DC%2BC38Xks1eqsrc%3D, PID: 22136423
-
Mukasa A, Takayanagi S, Saito K et al (2012) Significance of IDH mutations varies with tumor histology, grade, and genetics in Japanese glioma patients. Cancer Sci 103:587–592
-
(2012)
Cancer Sci
, vol.103
, pp. 587-592
-
-
Mukasa, A.1
Takayanagi, S.2
Saito, K.3
-
91
-
-
84871830221
-
p53 mutations in cancer
-
COI: 1:CAS:528:DC%2BC38XhvVOqs7nK, PID: 23263379
-
Muller PA, Vousden KH (2013) p53 mutations in cancer. Nat Cell Biol 15:2–8
-
(2013)
Nat Cell Biol
, vol.15
, pp. 2-8
-
-
Muller, P.A.1
Vousden, K.H.2
-
92
-
-
84881117564
-
Codeletion of 1p and 19q determines distinct gene methylation and expression profiles in IDH-mutated oligodendroglial tumors
-
COI: 1:CAS:528:DC%2BC3sXht1elurfF, PID: 23689617
-
Mur P, Mollejo M, Ruano Y et al (2013) Codeletion of 1p and 19q determines distinct gene methylation and expression profiles in IDH-mutated oligodendroglial tumors. Acta Neuropathol 126:277–289
-
(2013)
Acta Neuropathol
, vol.126
, pp. 277-289
-
-
Mur, P.1
Mollejo, M.2
Ruano, Y.3
-
93
-
-
84880783489
-
Current knowledge and treatment strategies for grade II gliomas
-
Narita Y (2013) Current knowledge and treatment strategies for grade II gliomas. Neurol Med Chir (Tokyo) 53:429–437
-
(2013)
Neurol Med Chir (Tokyo)
, vol.53
, pp. 429-437
-
-
Narita, Y.1
-
94
-
-
84927700873
-
Trends and outcomes in the treatment of gliomas based on data during 2001–2004 from the Brain Tumor Registry of Japan
-
Narita Y, Shibui S (2015) Trends and outcomes in the treatment of gliomas based on data during 2001–2004 from the Brain Tumor Registry of Japan. Neurol Med Chir (Tokyo)
-
(2015)
Neurol Med Chir (Tokyo)
-
-
Narita, Y.1
Shibui, S.2
-
95
-
-
1342300619
-
The complex identity of brain tumors: emerging concerns regarding origin, diversity and plasticity
-
COI: 1:CAS:528:DC%2BD2cXhsV2ms78%3D, PID: 15036880
-
Noble M, Dietrich J (2004) The complex identity of brain tumors: emerging concerns regarding origin, diversity and plasticity. Trends Neurosci 27:148–154
-
(2004)
Trends Neurosci
, vol.27
, pp. 148-154
-
-
Noble, M.1
Dietrich, J.2
-
96
-
-
77952108366
-
Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma
-
COI: 1:CAS:528:DC%2BC3cXmslKqsr0%3D, PID: 20399149
-
Noushmehr H, Weisenberger DJ, Diefes K et al (2010) Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma. Cancer Cell 17:510–522
-
(2010)
Cancer Cell
, vol.17
, pp. 510-522
-
-
Noushmehr, H.1
Weisenberger, D.J.2
Diefes, K.3
-
97
-
-
20344407807
-
Population-based studies on incidence, survival rates, and genetic alterations in astrocytic and oligodendroglial gliomas
-
COI: 1:CAS:528:DC%2BD2MXlvVSgsbg%3D, PID: 15977639
-
Ohgaki H, Kleihues P (2005) Population-based studies on incidence, survival rates, and genetic alterations in astrocytic and oligodendroglial gliomas. J Neuropathol Exp Neurol 64:479–489
-
(2005)
J Neuropathol Exp Neurol
, vol.64
, pp. 479-489
-
-
Ohgaki, H.1
Kleihues, P.2
-
98
-
-
84904741762
-
Quantitative metabolome analysis profiles activation of glutaminolysis in glioma with IDH1 mutation
-
COI: 1:CAS:528:DC%2BC2cXpvFGrtr8%3D, PID: 24590270
-
Ohka F, Ito M, Ranjit M et al (2014) Quantitative metabolome analysis profiles activation of glutaminolysis in glioma with IDH1 mutation. Tumour Biol 35:5911–5920
-
(2014)
Tumour Biol
, vol.35
, pp. 5911-5920
-
-
Ohka, F.1
Ito, M.2
Ranjit, M.3
-
99
-
-
84939979467
-
IDH mutation status and role of WHO grade and mitotic index in overall survival in grade II-III diffuse gliomas
-
Olar A, Wani KM, Alfaro-Munoz KD et al (2015) IDH mutation status and role of WHO grade and mitotic index in overall survival in grade II-III diffuse gliomas. Acta Neuropathol [Epub ahead of print]
-
(2015)
Acta Neuropathol [Epub ahead of print]
-
-
Olar, A.1
Wani, K.M.2
Alfaro-Munoz, K.D.3
-
100
-
-
84929620816
-
CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2007–2011
-
Ostrom QT, Gittleman H, Liao P et al (2014) CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2007–2011. Neuro Oncol 16(Suppl 4):iv1–iv63
-
(2014)
Neuro Oncol 16(Suppl 4):iv1–iv63
-
-
Ostrom, Q.T.1
Gittleman, H.2
Liao, P.3
-
101
-
-
65949116152
-
Prognostic significance of imaging contrast enhancement for WHO grade II gliomas
-
PID: 18697954
-
Pallud J, Capelle L, Taillandier L et al (2009) Prognostic significance of imaging contrast enhancement for WHO grade II gliomas. Neuro Oncol 11:176–182
-
(2009)
Neuro Oncol
, vol.11
, pp. 176-182
-
-
Pallud, J.1
Capelle, L.2
Taillandier, L.3
-
102
-
-
78249266888
-
Natural history of incidental World Health Organization grade II gliomas
-
PID: 21031584
-
Pallud J, Fontaine D, Duffau H et al (2010) Natural history of incidental World Health Organization grade II gliomas. Ann Neurol 68:727–733
-
(2010)
Ann Neurol
, vol.68
, pp. 727-733
-
-
Pallud, J.1
Fontaine, D.2
Duffau, H.3
-
103
-
-
52949127312
-
An integrated genomic analysis of human glioblastoma multiforme
-
COI: 1:CAS:528:DC%2BD1cXhtFCrtLrE, PID: 18772396
-
Parsons DW, Jones S, Zhang X et al (2008) An integrated genomic analysis of human glioblastoma multiforme. Science 321:1807–1812
-
(2008)
Science
, vol.321
, pp. 1807-1812
-
-
Parsons, D.W.1
Jones, S.2
Zhang, X.3
-
104
-
-
84925494546
-
Successive distinct high-grade gliomas in l-2-hydroxyglutaric aciduria
-
PID: 25338511
-
Patay Z, Orr BA, Shulkin BL et al (2014) Successive distinct high-grade gliomas in l-2-hydroxyglutaric aciduria. J Inherit Metab Dis 38:273–277
-
(2014)
J Inherit Metab Dis
, vol.38
, pp. 273-277
-
-
Patay, Z.1
Orr, B.A.2
Shulkin, B.L.3
-
105
-
-
49849090039
-
Improved grading and survival prediction of human astrocytic brain tumors by artificial neural network analysis of gene expression microarray data
-
COI: 1:CAS:528:DC%2BD1cXlvFanurs%3D, PID: 18445660
-
Petalidis LP, Oulas A, Backlund M et al (2008) Improved grading and survival prediction of human astrocytic brain tumors by artificial neural network analysis of gene expression microarray data. Mol Cancer Ther 7:1013–1024
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 1013-1024
-
-
Petalidis, L.P.1
Oulas, A.2
Backlund, M.3
-
106
-
-
34047207337
-
TP53 mutations in human cancers: functional selection and impact on cancer prognosis and outcomes
-
COI: 1:CAS:528:DC%2BD2sXjs1yqtL4%3D, PID: 17401424
-
Petitjean A, Achatz MI, Borresen-Dale AL, Hainaut P, Olivier M (2007) TP53 mutations in human cancers: functional selection and impact on cancer prognosis and outcomes. Oncogene 26:2157–2165
-
(2007)
Oncogene
, vol.26
, pp. 2157-2165
-
-
Petitjean, A.1
Achatz, M.I.2
Borresen-Dale, A.L.3
Hainaut, P.4
Olivier, M.5
-
107
-
-
34248379012
-
Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: lessons from recent developments in the IARC TP53 database
-
COI: 1:CAS:528:DC%2BD2sXmsVymur8%3D, PID: 17311302
-
Petitjean A, Mathe E, Kato S et al (2007) Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: lessons from recent developments in the IARC TP53 database. Hum Mutat 28:622–629
-
(2007)
Hum Mutat
, vol.28
, pp. 622-629
-
-
Petitjean, A.1
Mathe, E.2
Kato, S.3
-
108
-
-
33644820339
-
Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis
-
COI: 1:CAS:528:DC%2BD28XivFWjtL4%3D, PID: 16530701
-
Phillips HS, Kharbanda S, Chen R et al (2006) Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis. Cancer Cell 9:157–173
-
(2006)
Cancer Cell
, vol.9
, pp. 157-173
-
-
Phillips, H.S.1
Kharbanda, S.2
Chen, R.3
-
109
-
-
78951489314
-
IDH1 mutations are common in malignant gliomas arising in adolescents: a report from the Children’s Oncology Group
-
PID: 20725730
-
Pollack IF, Hamilton RL, Sobol RW et al (2011) IDH1 mutations are common in malignant gliomas arising in adolescents: a report from the Children’s Oncology Group. Childs Nerv Syst 27:87–94
-
(2011)
Childs Nerv Syst
, vol.27
, pp. 87-94
-
-
Pollack, I.F.1
Hamilton, R.L.2
Sobol, R.W.3
-
110
-
-
84863026682
-
Natural history and surgical management of incidentally discovered low-grade gliomas
-
PID: 21999317
-
Potts MB, Smith JS, Molinaro AM, Berger MS (2012) Natural history and surgical management of incidentally discovered low-grade gliomas. J Neurosurg 116:365–372
-
(2012)
J Neurosurg
, vol.116
, pp. 365-372
-
-
Potts, M.B.1
Smith, J.S.2
Molinaro, A.M.3
Berger, M.S.4
-
111
-
-
84877866746
-
Genomic analysis of diffuse pediatric low-grade gliomas identifies recurrent oncogenic truncating rearrangements in the transcription factor MYBL1
-
COI: 1:CAS:528:DC%2BC3sXhtV2ksL3L, PID: 23633565
-
Ramkissoon LA, Horowitz PM, Craig JM et al (2013) Genomic analysis of diffuse pediatric low-grade gliomas identifies recurrent oncogenic truncating rearrangements in the transcription factor MYBL1. Proc Natl Acad Sci USA 110:8188–8193
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 8188-8193
-
-
Ramkissoon, L.A.1
Horowitz, P.M.2
Craig, J.M.3
-
112
-
-
79952741730
-
Profiling the effects of isocitrate dehydrogenase 1 and 2 mutations on the cellular metabolome
-
COI: 1:CAS:528:DC%2BC3MXislGhtLc%3D, PID: 21289278
-
Reitman ZJ, Jin G, Karoly ED et al (2011) Profiling the effects of isocitrate dehydrogenase 1 and 2 mutations on the cellular metabolome. Proc Natl Acad Sci USA 108:3270–3275
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 3270-3275
-
-
Reitman, Z.J.1
Jin, G.2
Karoly, E.D.3
-
113
-
-
84920997237
-
Genetic dissection of leukemia-associated IDH1 and IDH2 mutants and d-2-hydroxyglutarate in Drosophila
-
COI: 1:CAS:528:DC%2BC2MXht12gt78%3D, PID: 25398939
-
Reitman ZJ, Sinenko SA, Spana EP, Yan H (2015) Genetic dissection of leukemia-associated IDH1 and IDH2 mutants and d-2-hydroxyglutarate in Drosophila. Blood 125:336–345
-
(2015)
Blood
, vol.125
, pp. 336-345
-
-
Reitman, Z.J.1
Sinenko, S.A.2
Spana, E.P.3
Yan, H.4
-
114
-
-
77954697566
-
Isocitrate dehydrogenase 1 and 2 mutations in cancer: alterations at a crossroads of cellular metabolism
-
COI: 1:CAS:528:DC%2BC3cXptlegs7c%3D, PID: 20513808
-
Reitman ZJ, Yan H (2010) Isocitrate dehydrogenase 1 and 2 mutations in cancer: alterations at a crossroads of cellular metabolism. J Natl Cancer Inst 102:932–941
-
(2010)
J Natl Cancer Inst
, vol.102
, pp. 932-941
-
-
Reitman, Z.J.1
Yan, H.2
-
115
-
-
84892621211
-
TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma
-
COI: 1:CAS:528:DC%2BC3sXhslait77N, PID: 24174164
-
Remke M, Ramaswamy V, Peacock J et al (2013) TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma. Acta Neuropathol 126:917–929
-
(2013)
Acta Neuropathol
, vol.126
, pp. 917-929
-
-
Remke, M.1
Ramaswamy, V.2
Peacock, J.3
-
116
-
-
84929712325
-
ATRX and IDH1-R132H immunohistochemistry with subsequent copy number analysis and IDH sequencing as a basis for an “integrated” diagnostic approach for adult astrocytoma, oligodendroglioma and glioblastoma
-
COI: 1:CAS:528:DC%2BC2cXitVert7rE, PID: 25427834
-
Reuss DE, Sahm F, Schrimpf D et al (2015) ATRX and IDH1-R132H immunohistochemistry with subsequent copy number analysis and IDH sequencing as a basis for an “integrated” diagnostic approach for adult astrocytoma, oligodendroglioma and glioblastoma. Acta Neuropathol 129:133–146
-
(2015)
Acta Neuropathol
, vol.129
, pp. 133-146
-
-
Reuss, D.E.1
Sahm, F.2
Schrimpf, D.3
-
117
-
-
78149405879
-
Molecular diagnostics of gliomas: state of the art
-
COI: 1:CAS:528:DC%2BC3cXhtlSjt77M, PID: 20714900
-
Riemenschneider MJ, Jeuken JW, Wesseling P, Reifenberger G (2010) Molecular diagnostics of gliomas: state of the art. Acta Neuropathol 120:567–584
-
(2010)
Acta Neuropathol
, vol.120
, pp. 567-584
-
-
Riemenschneider, M.J.1
Jeuken, J.W.2
Wesseling, P.3
Reifenberger, G.4
-
118
-
-
84877632013
-
An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells
-
COI: 1:CAS:528:DC%2BC3sXmslWksbg%3D, PID: 23558169
-
Rohle D, Popovici-Muller J, Palaskas N et al (2013) An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells. Science 340:626–630
-
(2013)
Science
, vol.340
, pp. 626-630
-
-
Rohle, D.1
Popovici-Muller, J.2
Palaskas, N.3
-
119
-
-
84885598200
-
Comparison of 2 monoclonal antibodies for immunohistochemical detection of BRAF V600E mutation in malignant melanoma, pulmonary carcinoma, gastrointestinal carcinoma, thyroid carcinoma, and gliomas
-
COI: 1:CAS:528:DC%2BC3sXhsFens7jE, PID: 24071017
-
Routhier CA, Mochel MC, Lynch K, Dias-Santagata D, Louis DN, Hoang MP (2013) Comparison of 2 monoclonal antibodies for immunohistochemical detection of BRAF V600E mutation in malignant melanoma, pulmonary carcinoma, gastrointestinal carcinoma, thyroid carcinoma, and gliomas. Hum Pathol 44:2563–2570
-
(2013)
Hum Pathol
, vol.44
, pp. 2563-2570
-
-
Routhier, C.A.1
Mochel, M.C.2
Lynch, K.3
Dias-Santagata, D.4
Louis, D.N.5
Hoang, M.P.6
-
120
-
-
84902500037
-
Analysis of IDH mutation, 1p/19q deletion, and PTEN loss delineates prognosis in clinical low-grade diffuse gliomas
-
COI: 1:CAS:528:DC%2BC2cXhtVaksrnF, PID: 24470545
-
Sabha N, Knobbe CB, Maganti M et al (2014) Analysis of IDH mutation, 1p/19q deletion, and PTEN loss delineates prognosis in clinical low-grade diffuse gliomas. Neuro Oncol 16:914–923
-
(2014)
Neuro Oncol
, vol.16
, pp. 914-923
-
-
Sabha, N.1
Knobbe, C.B.2
Maganti, M.3
-
121
-
-
84919921568
-
Farewell to oligoastrocytoma: in situ molecular genetics favor classification as either oligodendroglioma or astrocytoma
-
COI: 1:CAS:528:DC%2BC2cXhsVeqt73N, PID: 25143301
-
Sahm F, Reuss D, Koelsche C et al (2014) Farewell to oligoastrocytoma: in situ molecular genetics favor classification as either oligodendroglioma or astrocytoma. Acta Neuropathol 128:551–559
-
(2014)
Acta Neuropathol
, vol.128
, pp. 551-559
-
-
Sahm, F.1
Reuss, D.2
Koelsche, C.3
-
122
-
-
80655147991
-
Low-grade gliomas in adults
-
PID: 22043865
-
Sanai N, Chang S, Berger MS (2011) Low-grade gliomas in adults. J Neurosurg 115:948–965
-
(2011)
J Neurosurg
, vol.115
, pp. 948-965
-
-
Sanai, N.1
Chang, S.2
Berger, M.S.3
-
123
-
-
68949107664
-
Intracranial low-grade gliomas in adults: 30-year experience with long-term follow-up at Mayo Clinic
-
PID: 19018039
-
Schomas DA, Laack NN, Rao RD et al (2009) Intracranial low-grade gliomas in adults: 30-year experience with long-term follow-up at Mayo Clinic. Neuro Oncol 11:437–445
-
(2009)
Neuro Oncol
, vol.11
, pp. 437-445
-
-
Schomas, D.A.1
Laack, N.N.2
Rao, R.D.3
-
124
-
-
84906557615
-
A vaccine targeting mutant IDH1 induces antitumour immunity
-
COI: 1:CAS:528:DC%2BC2cXhsVSitrjM, PID: 25043048
-
Schumacher T, Bunse L, Pusch S et al (2014) A vaccine targeting mutant IDH1 induces antitumour immunity. Nature 512:324–327
-
(2014)
Nature
, vol.512
, pp. 324-327
-
-
Schumacher, T.1
Bunse, L.2
Pusch, S.3
-
125
-
-
84862777348
-
Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma
-
COI: 1:CAS:528:DC%2BC38XhtlOrsro%3D, PID: 22286061
-
Schwartzentruber J, Korshunov A, Liu XY et al (2012) Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma. Nature 482:226–231
-
(2012)
Nature
, vol.482
, pp. 226-231
-
-
Schwartzentruber, J.1
Korshunov, A.2
Liu, X.Y.3
-
126
-
-
84862182813
-
Radiotherapy and temozolomide in anaplastic astrocytoma: a retrospective multicenter study by the Central Nervous System Study Group of AIRO (Italian Association of Radiation Oncology)
-
COI: 1:CAS:528:DC%2BC38Xhtl2hsb%2FO, PID: 22539339
-
Scoccianti S, Magrini SM, Ricardi U et al (2012) Radiotherapy and temozolomide in anaplastic astrocytoma: a retrospective multicenter study by the Central Nervous System Study Group of AIRO (Italian Association of Radiation Oncology). Neuro Oncol 14:798–807
-
(2012)
Neuro Oncol
, vol.14
, pp. 798-807
-
-
Scoccianti, S.1
Magrini, S.M.2
Ricardi, U.3
-
127
-
-
78549283855
-
Inhibition of glutaminase preferentially slows growth of glioma cells with mutant IDH1
-
COI: 1:CAS:528:DC%2BC3cXhsVWmsL3N, PID: 21045145
-
Seltzer MJ, Bennett BD, Joshi AD et al (2010) Inhibition of glutaminase preferentially slows growth of glioma cells with mutant IDH1. Cancer Res 70:8981–8987
-
(2010)
Cancer Res
, vol.70
, pp. 8981-8987
-
-
Seltzer, M.J.1
Bennett, B.D.2
Joshi, A.D.3
-
128
-
-
58149145313
-
Recurrence following neurosurgeon-determined gross-total resection of adult supratentorial low-grade glioma: results of a prospective clinical trial
-
PID: 18976072
-
Shaw EG, Berkey B, Coons SW et al (2008) Recurrence following neurosurgeon-determined gross-total resection of adult supratentorial low-grade glioma: results of a prospective clinical trial. J Neurosurg 109:835–841
-
(2008)
J Neurosurg
, vol.109
, pp. 835-841
-
-
Shaw, E.G.1
Berkey, B.2
Coons, S.W.3
-
129
-
-
84865785710
-
Randomized trial of radiation therapy plus procarbazine, lomustine, and vincristine chemotherapy for supratentorial adult low-grade glioma: initial results of RTOG 9802
-
COI: 1:CAS:528:DC%2BC38XhsVKlsLjF, PID: 22851558
-
Shaw EG, Wang M, Coons SW et al (2012) Randomized trial of radiation therapy plus procarbazine, lomustine, and vincristine chemotherapy for supratentorial adult low-grade glioma: initial results of RTOG 9802. J Clin Oncol 30:3065–3070
-
(2012)
J Clin Oncol
, vol.30
, pp. 3065-3070
-
-
Shaw, E.G.1
Wang, M.2
Coons, S.W.3
-
130
-
-
84879092884
-
Outcomes for patients with anaplastic astrocytoma treated with chemoradiation, radiation therapy alone or radiation therapy followed by chemotherapy: a retrospective review within the era of temozolomide
-
COI: 1:CAS:528:DC%2BC3sXptlKmtro%3D, PID: 23526410
-
Shonka NA, Theeler B, Cahill D et al (2013) Outcomes for patients with anaplastic astrocytoma treated with chemoradiation, radiation therapy alone or radiation therapy followed by chemotherapy: a retrospective review within the era of temozolomide. J Neurooncol 113:305–311
-
(2013)
J Neurooncol
, vol.113
, pp. 305-311
-
-
Shonka, N.A.1
Theeler, B.2
Cahill, D.3
-
131
-
-
70449098981
-
Pediatric low-grade gliomas
-
PID: 19841428
-
Sievert AJ, Fisher MJ (2009) Pediatric low-grade gliomas. J Child Neurol 24:1397–1408
-
(2009)
J Child Neurol
, vol.24
, pp. 1397-1408
-
-
Sievert, A.J.1
Fisher, M.J.2
-
132
-
-
33749993417
-
The consensus coding sequences of human breast and colorectal cancers
-
PID: 16959974
-
Sjoblom T, Jones S, Wood LD et al (2006) The consensus coding sequences of human breast and colorectal cancers. Science 314:268–274
-
(2006)
Science
, vol.314
, pp. 268-274
-
-
Sjoblom, T.1
Jones, S.2
Wood, L.D.3
-
133
-
-
41649090186
-
Role of extent of resection in the long-term outcome of low-grade hemispheric gliomas
-
PID: 18323558
-
Smith JS, Chang EF, Lamborn KR et al (2008) Role of extent of resection in the long-term outcome of low-grade hemispheric gliomas. J Clin Oncol 26:1338–1345
-
(2008)
J Clin Oncol
, vol.26
, pp. 1338-1345
-
-
Smith, J.S.1
Chang, E.F.2
Lamborn, K.R.3
-
134
-
-
77955817286
-
Guidelines on management of low-grade gliomas: report of an EFNS-EANO Task Force
-
COI: 1:STN:280:DC%2BC3cjlvVCqtg%3D%3D, PID: 20718851
-
Soffietti R, Baumert BG, Bello L et al (2010) Guidelines on management of low-grade gliomas: report of an EFNS-EANO Task Force. Eur J Neurol 17:1124–1133
-
(2010)
Eur J Neurol
, vol.17
, pp. 1124-1133
-
-
Soffietti, R.1
Baumert, B.G.2
Bello, L.3
-
135
-
-
70349594347
-
Analysis of IDH1 and IDH2 mutations in Japanese glioma patients
-
COI: 1:CAS:528:DC%2BD1MXht12qs7bP, PID: 19765000
-
Sonoda Y, Kumabe T, Nakamura T et al (2009) Analysis of IDH1 and IDH2 mutations in Japanese glioma patients. Cancer Sci 100:1996–1998
-
(2009)
Cancer Sci
, vol.100
, pp. 1996-1998
-
-
Sonoda, Y.1
Kumabe, T.2
Nakamura, T.3
-
136
-
-
84929129626
-
-
Mutational landscape and clonal architecture in grade II and III gliomas, Nat Genet [Epub ahead of print]
-
Suzuki H, Aoki K, Chiba K et al (2015) Mutational landscape and clonal architecture in grade II and III gliomas. Nat Genet [Epub ahead of print]
-
(2015)
Chiba K et al
-
-
Suzuki, H.1
Aoki, K.2
-
137
-
-
84918568911
-
Revisiting TP53 mutations and immunohistochemistry—a comparative study in 157 diffuse gliomas
-
Takami H, Yoshida A, Fukushima S et al (2014) Revisiting TP53 mutations and immunohistochemistry—a comparative study in 157 diffuse gliomas. Brain Pathol [Epub ahead of print]
-
(2014)
Brain Pathol [Epub ahead of print]
-
-
Takami, H.1
Yoshida, A.2
Fukushima, S.3
-
138
-
-
80052780994
-
Detection of IDH1 mutation in human gliomas: comparison of immunohistochemistry and sequencing
-
COI: 1:CAS:528:DC%2BC3MXhtFGjs7rO, PID: 21344322
-
Takano S, Tian W, Matsuda M et al (2011) Detection of IDH1 mutation in human gliomas: comparison of immunohistochemistry and sequencing. Brain Tumor Pathol 28:115–123
-
(2011)
Brain Tumor Pathol
, vol.28
, pp. 115-123
-
-
Takano, S.1
Tian, W.2
Matsuda, M.3
-
139
-
-
0037441933
-
Prognostic implication of clinical, radiologic, and pathologic features in patients with anaplastic gliomas
-
PID: 12569607
-
Tortosa A, Vinolas N, Villa S et al (2003) Prognostic implication of clinical, radiologic, and pathologic features in patients with anaplastic gliomas. Cancer 97:1063–1071
-
(2003)
Cancer
, vol.97
, pp. 1063-1071
-
-
Tortosa, A.1
Vinolas, N.2
Villa, S.3
-
140
-
-
84858796263
-
IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype
-
COI: 1:CAS:528:DC%2BC38XisVKktLc%3D, PID: 22343889
-
Turcan S, Rohle D, Goenka A et al (2012) IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype. Nature 483:479–483
-
(2012)
Nature
, vol.483
, pp. 479-483
-
-
Turcan, S.1
Rohle, D.2
Goenka, A.3
-
141
-
-
24944439786
-
Long-term efficacy of early versus delayed radiotherapy for low-grade astrocytoma and oligodendroglioma in adults: the EORTC 22845 randomised trial
-
PID: 16168780
-
van den Bent MJ, Afra D, de Witte O et al (2005) Long-term efficacy of early versus delayed radiotherapy for low-grade astrocytoma and oligodendroglioma in adults: the EORTC 22845 randomised trial. Lancet 366:985–990
-
(2005)
Lancet
, vol.366
, pp. 985-990
-
-
van den Bent, M.J.1
Afra, D.2
de Witte, O.3
-
142
-
-
84873345824
-
Adjuvant procarbazine, lomustine, and vincristine chemotherapy in newly diagnosed anaplastic oligodendroglioma: long-term follow-up of EORTC brain tumor group study 26951
-
PID: 23071237
-
van den Bent MJ, Brandes AA, Taphoorn MJ et al (2013) Adjuvant procarbazine, lomustine, and vincristine chemotherapy in newly diagnosed anaplastic oligodendroglioma: long-term follow-up of EORTC brain tumor group study 26951. J Clin Oncol 31:344–350
-
(2013)
J Clin Oncol
, vol.31
, pp. 344-350
-
-
van den Bent, M.J.1
Brandes, A.A.2
Taphoorn, M.J.3
-
143
-
-
84877825900
-
Interlaboratory comparison of IDH mutation detection
-
PID: 23358936
-
van den Bent MJ, Hartmann C, Preusser M et al (2013) Interlaboratory comparison of IDH mutation detection. J Neurooncol 112:173–178
-
(2013)
J Neurooncol
, vol.112
, pp. 173-178
-
-
van den Bent, M.J.1
Hartmann, C.2
Preusser, M.3
-
144
-
-
84882273357
-
Evaluation of histone 3 lysine 27 trimethylation (H3K27me3) and enhancer of Zest 2 (EZH2) in pediatric glial and glioneuronal tumors shows decreased H3K27me3 in H3F3A K27M mutant glioblastomas
-
Venneti S, Garimella MT, Sullivan LM et al (2013) Evaluation of histone 3 lysine 27 trimethylation (H3K27me3) and enhancer of Zest 2 (EZH2) in pediatric glial and glioneuronal tumors shows decreased H3K27me3 in H3F3A K27M mutant glioblastomas. Brain Pathol
-
(2013)
Bra
-
-
Venneti, S.1
Garimella, M.T.2
Sullivan, L.M.3
-
145
-
-
84919928729
-
A sensitive and specific histopathologic prognostic marker for H3F3A K27M mutant pediatric glioblastomas
-
COI: 1:CAS:528:DC%2BC2cXhsFGhu77P, PID: 25200322
-
Venneti S, Santi M, Felicella MM et al (2014) A sensitive and specific histopathologic prognostic marker for H3F3A K27M mutant pediatric glioblastomas. Acta Neuropathol 128:743–753
-
(2014)
Acta Neuropathol
, vol.128
, pp. 743-753
-
-
Venneti, S.1
Santi, M.2
Felicella, M.M.3
-
146
-
-
73649123907
-
Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1
-
COI: 1:CAS:528:DC%2BC3cXkvFKgsL4%3D, PID: 20129251
-
Verhaak RG, Hoadley KA, Purdom E et al (2010) Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell 17:98–110
-
(2010)
Cancer Cell
, vol.17
, pp. 98-110
-
-
Verhaak, R.G.1
Hoadley, K.A.2
Purdom, E.3
-
147
-
-
0034676455
-
Surfing the p53 network
-
COI: 1:CAS:528:DC%2BD3cXosVemtrY%3D, PID: 11099028
-
Vogelstein B, Lane D, Levine AJ (2000) Surfing the p53 network. Nature 408:307–310
-
(2000)
Nature
, vol.408
, pp. 307-310
-
-
Vogelstein, B.1
Lane, D.2
Levine, A.J.3
-
148
-
-
84901755190
-
Targetable signaling pathway mutations are associated with malignant phenotype in IDH-mutant gliomas
-
COI: 1:CAS:528:DC%2BC2cXpt1KksLc%3D, PID: 24714777
-
Wakimoto H, Tanaka S, Curry WT et al (2014) Targetable signaling pathway mutations are associated with malignant phenotype in IDH-mutant gliomas. Clin Cancer Res 20:2898–2909
-
(2014)
Clin Cancer Res
, vol.20
, pp. 2898-2909
-
-
Wakimoto, H.1
Tanaka, S.2
Curry, W.T.3
-
149
-
-
12144289677
-
Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF
-
COI: 1:CAS:528:DC%2BD2cXivVyksLw%3D, PID: 15035987
-
Wan PT, Garnett MJ, Roe SM et al (2004) Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF. Cell 116:855–867
-
(2004)
Cell
, vol.116
, pp. 855-867
-
-
Wan, P.T.1
Garnett, M.J.2
Roe, S.M.3
-
150
-
-
84877620952
-
Targeted inhibition of mutant IDH2 in leukemia cells induces cellular differentiation
-
COI: 1:CAS:528:DC%2BC3sXmslWksbs%3D, PID: 23558173
-
Wang F, Travins J, DeLaBarre B et al (2013) Targeted inhibition of mutant IDH2 in leukemia cells induces cellular differentiation. Science 340:622–626
-
(2013)
Science
, vol.340
, pp. 622-626
-
-
Wang, F.1
Travins, J.2
DeLaBarre, B.3
-
151
-
-
65349150503
-
IDH1 mutations are early events in the development of astrocytomas and oligodendrogliomas
-
COI: 1:CAS:528:DC%2BD1MXksVOksLY%3D, PID: 19246647
-
Watanabe T, Nobusawa S, Kleihues P, Ohgaki H (2009) IDH1 mutations are early events in the development of astrocytomas and oligodendrogliomas. Am J Pathol 174:1149–1153
-
(2009)
Am J Pathol
, vol.174
, pp. 1149-1153
-
-
Watanabe, T.1
Nobusawa, S.2
Kleihues, P.3
Ohgaki, H.4
-
152
-
-
67349220062
-
Selective acquisition of IDH1 R132C mutations in astrocytomas associated with Li–Fraumeni syndrome
-
COI: 1:CAS:528:DC%2BD1MXlvFOksb8%3D, PID: 19340432
-
Watanabe T, Vital A, Nobusawa S, Kleihues P, Ohgaki H (2009) Selective acquisition of IDH1 R132C mutations in astrocytomas associated with Li–Fraumeni syndrome. Acta Neuropathol 117:653–656
-
(2009)
Acta Neuropathol
, vol.117
, pp. 653-656
-
-
Watanabe, T.1
Vital, A.2
Nobusawa, S.3
Kleihues, P.4
Ohgaki, H.5
-
153
-
-
84904902698
-
EANO guideline for the diagnosis and treatment of anaplastic gliomas and glioblastoma
-
PID: 25079102
-
Weller M, van den Bent M, Hopkins K et al (2014) EANO guideline for the diagnosis and treatment of anaplastic gliomas and glioblastoma. Lancet Oncol 15:e395–e403
-
(2014)
Lancet Oncol
, vol.15
, pp. 395-403
-
-
Weller, M.1
van den Bent, M.2
Hopkins, K.3
-
154
-
-
73349134695
-
NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with procarbazine, lomustine, and vincristine or temozolomide
-
COI: 1:CAS:528:DC%2BC3cXhtVWis7g%3D, PID: 19901110
-
Wick W, Hartmann C, Engel C et al (2009) NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with procarbazine, lomustine, and vincristine or temozolomide. J Clin Oncol 27:5874–5880
-
(2009)
J Clin Oncol
, vol.27
, pp. 5874-5880
-
-
Wick, W.1
Hartmann, C.2
Engel, C.3
-
155
-
-
84863091424
-
Temozolomide chemotherapy alone versus radiotherapy alone for malignant astrocytoma in the elderly: the NOA-08 randomised, phase 3 trial
-
COI: 1:CAS:528:DC%2BC38XhtVShtrjK, PID: 22578793
-
Wick W, Platten M, Meisner C et al (2012) Temozolomide chemotherapy alone versus radiotherapy alone for malignant astrocytoma in the elderly: the NOA-08 randomised, phase 3 trial. Lancet Oncol 13:707–715
-
(2012)
Lancet Oncol
, vol.13
, pp. 707-715
-
-
Wick, W.1
Platten, M.2
Meisner, C.3
-
156
-
-
84883464949
-
ATRX loss refines the classification of anaplastic gliomas and identifies a subgroup of IDH mutant astrocytic tumors with better prognosis
-
COI: 1:CAS:528:DC%2BC3sXhtlyitLfK, PID: 23904111
-
Wiestler B, Capper D, Holland-Letz T et al (2013) ATRX loss refines the classification of anaplastic gliomas and identifies a subgroup of IDH mutant astrocytic tumors with better prognosis. Acta Neuropathol 126:443–451
-
(2013)
Acta Neuropathol
, vol.126
, pp. 443-451
-
-
Wiestler, B.1
Capper, D.2
Holland-Letz, T.3
-
157
-
-
84929712250
-
Assessing CpG island methylator phenotype, 1p/19q codeletion, and MGMT promoter methylation from epigenome-wide data in the biomarker cohort of the NOA-04 trial
-
PID: 25028501
-
Wiestler B, Capper D, Hovestadt V et al (2014) Assessing CpG island methylator phenotype, 1p/19q codeletion, and MGMT promoter methylation from epigenome-wide data in the biomarker cohort of the NOA-04 trial. Neuro Oncol 16:1630–1638
-
(2014)
Neuro Oncol
, vol.16
, pp. 1630-1638
-
-
Wiestler, B.1
Capper, D.2
Hovestadt, V.3
-
158
-
-
84929999099
-
Integrated DNA methylation and copy-number profiling identify three clinically and biologically relevant groups of anaplastic glioma
-
COI: 1:CAS:528:DC%2BC2cXhtFCqtr3O, PID: 25008768
-
Wiestler B, Capper D, Sill M et al (2014) Integrated DNA methylation and copy-number profiling identify three clinically and biologically relevant groups of anaplastic glioma. Acta Neuropathol 128:561–571
-
(2014)
Acta Neuropathol
, vol.128
, pp. 561-571
-
-
Wiestler, B.1
Capper, D.2
Sill, M.3
-
159
-
-
77649262618
-
ATRX interacts with H3.3 in maintaining telomere structural integrity in pluripotent embryonic stem cells
-
COI: 1:CAS:528:DC%2BC3cXjtlCktbk%3D, PID: 20110566
-
Wong LH, McGhie JD, Sim M et al (2010) ATRX interacts with H3.3 in maintaining telomere structural integrity in pluripotent embryonic stem cells. Genome Res 20:351–360
-
(2010)
Genome Res
, vol.20
, pp. 351-360
-
-
Wong, L.H.1
McGhie, J.D.2
Sim, M.3
-
160
-
-
84862777410
-
Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas
-
COI: 1:CAS:528:DC%2BC38XhtlOlsb4%3D, PID: 22286216
-
Wu G, Broniscer A, McEachron TA et al (2012) Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas. Nat Genet 44:251–253
-
(2012)
Nat Genet
, vol.44
, pp. 251-253
-
-
Wu, G.1
Broniscer, A.2
McEachron, T.A.3
-
161
-
-
78651463452
-
Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of alpha-ketoglutarate-dependent dioxygenases
-
COI: 1:CAS:528:DC%2BC3MXpvValsQ%3D%3D, PID: 21251613
-
Xu W, Yang H, Liu Y et al (2011) Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of alpha-ketoglutarate-dependent dioxygenases. Cancer Cell 19:17–30
-
(2011)
Cancer Cell
, vol.19
, pp. 17-30
-
-
Xu, W.1
Yang, H.2
Liu, Y.3
-
162
-
-
60849115270
-
IDH1 and IDH2 mutations in gliomas
-
COI: 1:CAS:528:DC%2BD1MXitFWru7o%3D, PID: 19228619
-
Yan H, Parsons DW, Jin G et al (2009) IDH1 and IDH2 mutations in gliomas. N Engl J Med 360:765–773
-
(2009)
N Engl J Med
, vol.360
, pp. 765-773
-
-
Yan, H.1
Parsons, D.W.2
Jin, G.3
-
163
-
-
84878723078
-
Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas
-
COI: 1:CAS:528:DC%2BC3sXlsl2jt7c%3D, PID: 23583981
-
Zhang J, Wu G, Miller CP et al (2013) Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas. Nat Genet 45:602–612
-
(2013)
Nat Genet
, vol.45
, pp. 602-612
-
-
Zhang, J.1
Wu, G.2
Miller, C.P.3
-
164
-
-
0035883954
-
Transcription regulation by histone methylation: interplay between different covalent modifications of the core histone tails
-
COI: 1:CAS:528:DC%2BD3MXnsV2hs7s%3D, PID: 11562345
-
Zhang Y, Reinberg D (2001) Transcription regulation by histone methylation: interplay between different covalent modifications of the core histone tails. Genes Dev 15:2343–2360
-
(2001)
Genes Dev
, vol.15
, pp. 2343-2360
-
-
Zhang, Y.1
Reinberg, D.2
-
165
-
-
64849098267
-
Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF-1alpha
-
COI: 1:CAS:528:DC%2BD1MXktFals7g%3D, PID: 19359588
-
Zhao S, Lin Y, Xu W et al (2009) Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF-1alpha. Science 324:261–265
-
(2009)
Science
, vol.324
, pp. 261-265
-
-
Zhao, S.1
Lin, Y.2
Xu, W.3
-
166
-
-
84930453187
-
-
Baker SJ: Cell of origin for malignant gliomas and its implication in therapeutic development. Cold Spring Harb Perspect Biol [Epub ahead of print]
-
Zong H, Parada LF, Baker SJ (2015) Cell of origin for malignant gliomas and its implication in therapeutic development. Cold Spring Harb Perspect Biol [Epub ahead of print]
-
(2015)
Parada LF
-
-
Zong, H.1
|