Specific detection of methionine 27 mutation in histone 3 variants (H3K27M) in fixed tissue from high-grade astrocytomas

Acta Neuropathologica

Volumn 128, Issue 5, 2014, Pages 733-741

  Bechet, Denise ^a   Gielen, Gerrit G H ^b   Korshunov, Andrey ^c   Pfister, Stefan M ^c   Rousso, Caterina ^d   Faury, Damien ^d   Fiset, Pierre Olivier ^d   Benlimane, Naciba ^e   Lewis, Peter W ^f   Lu, Chao ^g   David Allis, C ^g   Kieran, Mark W ^h   Ligon, Keith L ⁱ   Pietsch, Torsten ^b   Ellezam, Benjamin ^j   Albrecht, Steffen ^d   Jabado, Nada ^a,d  

^a MCGILL UNIVERSITY   (Canada)

^b UNIVERSITY HOSPITAL BONN   (Germany)

^c GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^d MONTREAL CHILDREN S HOSPITAL   (Canada)

^e MCGILL UNIVERSITY   (Canada)

^f UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^g ROCKEFELLER UNIVERSITY   (United States)

^h HARVARD MEDICAL SCHOOL   (United States)

ⁱ HARVARD UNIVERSITY   (United States)

^j UNIVERSITY OF MONTREAL   (Canada)

more..

Author keywords

High grade astrocytomas; Histone 3 variants; IHC; K27 trimethylation; K27M

Indexed keywords

HISTONE H3; METHIONINE; HISTONE;

ARTICLE; ASTROCYTOMA; BRAIN TISSUE; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DIAGNOSTIC TEST ACCURACY STUDY; ENDOTHELIUM CELL; FEMALE; GENE EXPRESSION; GENE MUTATION; GENETIC VARIABILITY; GENOTYPE; HIGH GRADE ASTROCYTOMA; HISTONE MODIFICATION; HUMAN; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LYMPHOCYTE; MALE; MICROGLIA; PYROSEQUENCING; SCHOOL CHILD; SENSITIVITY AND SPECIFICITY; SMOOTH MUSCLE FIBER; STAINING; TUMOR RECURRENCE; VASCULAR SMOOTH MUSCLE; ADOLESCENT; BRAIN; BRAIN TUMOR; COHORT ANALYSIS; GENETICS; METABOLISM; MUTATION; NUCLEOTIDE SEQUENCE; PATHOLOGY;

ADOLESCENT; ASTROCYTOMA; BRAIN; BRAIN NEOPLASMS; CHILD; COHORT STUDIES; DNA MUTATIONAL ANALYSIS; FEMALE; GENOTYPE; HISTONES; HUMANS; MALE; METHIONINE; MUTATION;

EID: 84919924438     PISSN: 00016322     EISSN: 14320533     Source Type: Journal    
DOI: 10.1007/s00401-014-1337-4     Document Type: Article

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