-
1
-
-
78649346692
-
The heat shock response: Life on the verge of death
-
Richter K, Haslbeck M, Buchner J. The heat shock response: life on the verge of death. Mol Cell 2010;40:253-66
-
(2010)
Mol Cell
, vol.40
, pp. 253-266
-
-
Richter, K.1
Haslbeck, M.2
Buchner, J.3
-
2
-
-
0016373748
-
Protein synthesis in salivary glands of Drosophila melanogaster: Relation to chromosome puffs
-
Tissieres A, Mitchell HK, Tracy UM. Protein synthesis in salivary glands of Drosophila melanogaster: relation to chromosome puffs. J Mol Biol 1974;84: 389-98
-
(1974)
J Mol Biol
, vol.84
, pp. 389-398
-
-
Tissieres, A.1
Mitchell, H.K.2
Tracy, U.M.3
-
3
-
-
77957841871
-
Independent evolution of the core domain and its flanking sequences in small heat shock proteins
-
Kriehuber T, Rattei T, Weinmaier T, et al. Independent evolution of the core domain and its flanking sequences in small heat shock proteins. FASEB J 2010;24:3633-42
-
(2010)
FASEB J
, vol.24
, pp. 3633-3642
-
-
Kriehuber, T.1
Rattei, T.2
Weinmaier, T.3
-
4
-
-
0033545355
-
Molecular chaperones: Small heat shock proteins in the limelight
-
van den IJssel PR, Norman DG, Quinlan RA. Molecular chaperones: small heat shock proteins in the limelight. Curr Biol 1999;9:R103-R5
-
(1999)
Curr Biol
, vol.9
, pp. R103-R5
-
-
Van Den Ijssel, P.R.1
Norman, D.G.2
Quinlan, R.A.3
-
6
-
-
0035847115
-
Interaction between alpha B-crystallin and the human 20S proteasomal subunit C8/ alpha
-
Boelens WC, Croes Y, De Jong WW. Interaction between alpha B-crystallin and the human 20S proteasomal subunit C8/ alpha. Bioch Biophys Acta 2001;1544: 311-19
-
(2001)
Bioch Biophys Acta
, vol.1544
, pp. 311-319
-
-
Boelens, W.C.1
Croes, Y.2
De Jong, W.W.3
-
7
-
-
77649272915
-
Ubiquitin-proteasome-mediated degradation and synthesis of MyoD is modulated by alphaB-crystallin, a small heat shock protein, during muscle differentiation
-
Singh BN, Rao KS, Rao Ch M. Ubiquitin-proteasome-mediated degradation and synthesis of MyoD is modulated by alphaB-crystallin, a small heat shock protein, during muscle differentiation. Biochim Biophys Acta 2010;1803:288-99
-
(2010)
Biochim Biophys Acta
, vol.1803
, pp. 288-299
-
-
Singh, B.N.1
Rao, K.S.2
Rao Ch., M.3
-
8
-
-
2442681777
-
Human alphaA- and alphaB-crystallins bind to Bax and Bcl-X(S) to sequester their translocation during staurosporine-induced apoptosis
-
Mao YW, Liu JP, Xiang H, Li DW. Human alphaA- and alphaB-crystallins bind to Bax and Bcl-X(S) to sequester their translocation during staurosporine-induced apoptosis. Cell Death Differ 2004;11: 512-26
-
(2004)
Cell Death Differ
, vol.11
, pp. 512-526
-
-
Mao, Y.W.1
Liu, J.P.2
Xiang, H.3
Li, D.W.4
-
9
-
-
33846297971
-
Small heat shock protein alphaB-crystallin binds to p53 to sequester its translocation to mitochondria during hydrogen peroxide-induced apoptosis
-
Liu S, Li J, Tao Y, Xiao X. Small heat shock protein alphaB-crystallin binds to p53 to sequester its translocation to mitochondria during hydrogen peroxide-induced apoptosis. Biochem Biophys Res Commun 2007;354:109-14
-
(2007)
Biochem Biophys Res Commun
, vol.354
, pp. 109-114
-
-
Liu, S.1
Li, J.2
Tao, Y.3
Xiao, X.4
-
10
-
-
77951448229
-
AlphaB-crystallin regulation of angiogenesis by modulation of VEGF
-
Kase S, He S, Sonoda S, et al. alphaB-crystallin regulation of angiogenesis by modulation of VEGF. Blood 2010;115: 3398-406
-
(2010)
Blood
, vol.115
, pp. 3398-3406
-
-
Kase, S.1
He, S.2
Sonoda, S.3
-
11
-
-
0037325497
-
Alpha-crystallin
-
Horwitz J. Alpha-crystallin. Exp Eye Res 2003;76:145-53
-
(2003)
Exp Eye Res
, vol.76
, pp. 145-153
-
-
Horwitz, J.1
-
12
-
-
84878325081
-
Evolution of crystallins for a role in the vertebrate eye lens
-
Slingsby C, Wistow GJ, Clark AR. Evolution of crystallins for a role in the vertebrate eye lens. Protein Sci 2013;22: 367-80 . Discusses the current understanding of the function of the different crystallins in the eye lens and explains their influence on the refractive index.
-
(2013)
Protein Sci
, vol.22
, pp. 367-380
-
-
Slingsby, C.1
Wistow, G.J.2
Clark, A.R.3
-
13
-
-
84878932295
-
Human small heat shock proteins: Protein interactomes of homo- and hetero-oligomeric complexes: An update
-
Arrigo AP. Human small heat shock proteins: protein interactomes of homo- and hetero-oligomeric complexes: an update. FEBS Lett 2013;587:1959-69 . Comprehensive summary of all described interactions of HSPBs, indicating a first subdivision of interaction types.
-
(2013)
FEBS Lett
, vol.587
, pp. 1959-1969
-
-
Arrigo, A.P.1
-
14
-
-
84867401896
-
Novel roles for alpha-crystallins in retinal function and disease
-
Kannan R, Sreekumar PG, Hinton DR. Novel roles for alpha-crystallins in retinal function and disease. Prog Retin Eye Res 2012;31:576-604
-
(2012)
Prog Retin Eye Res
, vol.31
, pp. 576-604
-
-
Kannan, R.1
Sreekumar, P.G.2
Hinton, D.R.3
-
15
-
-
84883852928
-
Different anti-aggregation and pro-degradative functions of the members of the mammalian sHSP family in neurological disorders
-
Carra S, Rusmini P, Crippa V, et al. Different anti-aggregation and pro-degradative functions of the members of the mammalian sHSP family in neurological disorders. Philos Trans R Soc Lond B Biol Sci 2013;368:20110409
-
(2013)
Philos Trans R Soc Lond B Biol Sci
, vol.368
, pp. 20110409
-
-
Carra, S.1
Rusmini, P.2
Crippa, V.3
-
16
-
-
64549097439
-
Guidelines for the nomenclature of the human heat shock proteins
-
Kampinga HH, Hageman J, Vos MJ, et al. Guidelines for the nomenclature of the human heat shock proteins. Cell Stress Chaperones 2009;14:105-11
-
(2009)
Cell Stress Chaperones
, vol.14
, pp. 105-111
-
-
Kampinga, H.H.1
Hageman, J.2
Vos, M.J.3
-
17
-
-
20444478694
-
The small heat shock proteins and their role in human disease
-
Sun Y, MacRae TH. The small heat shock proteins and their role in human disease. FEBS J 2005;272:2613-27
-
(2005)
FEBS J
, vol.272
, pp. 2613-2627
-
-
Sun, Y.1
Macrae, T.H.2
-
18
-
-
84921058797
-
Small heat shock proteins: Role in cellular functions and pathology
-
Bakthisaran R, Tangirala R, Rao CM. Small heat shock proteins: Role in cellular functions and pathology. Biochim Biophys Acta 2014;1854:291-319 . Comprehensive collection of implications of sHsps in diseases and pathology.
-
(2014)
Biochim Biophys Acta
, vol.1854
, pp. 291-319
-
-
Bakthisaran, R.1
Tangirala, R.2
Rao, C.M.3
-
19
-
-
84864456309
-
HSPBs: Small proteins with big implications in human disease
-
Kampinga HH, Garrido C. HSPBs: small proteins with big implications in human disease. Int J Biochem Cell Biol 2012;44: 1706-10 . Critical, short summary of implications of sHsps in diseases.
-
(2012)
Int J Biochem Cell Biol
, vol.44
, pp. 1706-1710
-
-
Kampinga, H.H.1
Garrido, C.2
-
20
-
-
0037358061
-
The human genome encodes 10 alpha-crystallin-related small heat shock proteins: HspB1-10
-
Kappe G, Franck E, Verschuure P, et al. The human genome encodes 10 alpha-crystallin-related small heat shock proteins: HspB1-10. Cell Stress Chaperones 2003;8:53-61
-
(2003)
Cell Stress Chaperones
, vol.8
, pp. 53-61
-
-
Kappe, G.1
Franck, E.2
Verschuure, P.3
-
21
-
-
84929576317
-
Divergence in the effects upon intermediate filaments of the cataract inducing mutation R120G within the sHSP family
-
Perng MD, Muchowski PJ, Clarke JI, et al. Divergence in the effects upon intermediate filaments of the cataract inducing mutation R120G within the sHSP family. Invest Opht Vis Sci 2001;42:S874-S
-
(2001)
Invest Opht Vis Sci
, vol.42
, pp. S874-S
-
-
Perng, M.D.1
Muchowski, P.J.2
Clarke, J.I.3
-
22
-
-
2642539919
-
Hot-spot residue in small heat-shock protein 22 causes distal motor neuropathy
-
Irobi J, Van Impe K, Seeman P, et al. Hot-spot residue in small heat-shock protein 22 causes distal motor neuropathy. Nat Genet 2004;36:597-601
-
(2004)
Nat Genet
, vol.36
, pp. 597-601
-
-
Irobi, J.1
Van Impe, K.2
Seeman, P.3
-
23
-
-
84855480113
-
Multiple molecular architectures of the eye lens chaperone alphaB-crystallin elucidated by a triple hybrid approach
-
Braun N, Zacharias M, Peschek J, et al. Multiple molecular architectures of the eye lens chaperone alphaB-crystallin elucidated by a triple hybrid approach. Proc Natl Acad Sci USA 2011;108:20491-6
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 20491-20496
-
-
Braun, N.1
Zacharias, M.2
Peschek, J.3
-
24
-
-
84885081139
-
Regulated structural transitions unleash the chaperone activity of alphaB-crystallin
-
Peschek J, Braun N, Rohrberg J, et al. Regulated structural transitions unleash the chaperone activity of alphaB-crystallin. Proc Natl Acad Sci USA 2013;110:E3780-9
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. E3780-E3789
-
-
Peschek, J.1
Braun, N.2
Rohrberg, J.3
-
25
-
-
77957296137
-
Crystal structures of truncated alphaA and alphaB crystallins reveal structural mechanisms of polydispersity important for eye lens function
-
Laganowsky A, Benesch JL, Landau M, et al. Crystal structures of truncated alphaA and alphaB crystallins reveal structural mechanisms of polydispersity important for eye lens function. Protein Sci 2010;19:1031-43
-
(2010)
Protein Sci
, vol.19
, pp. 1031-1043
-
-
Laganowsky, A.1
Benesch, J.L.2
Landau, M.3
-
26
-
-
84899118154
-
The structured core domain of alphaB-crystallin can prevent amyloid fibrillation and associated toxicity
-
Hochberg GK, Ecroyd H, Liu C, et al. The structured core domain of alphaB-crystallin can prevent amyloid fibrillation and associated toxicity. Proc Natl Acad Sci USA 2014;111:E1562-70
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, pp. E1562-E1570
-
-
Hochberg, G.K.1
Ecroyd, H.2
Liu, C.3
-
27
-
-
77956340380
-
Solid-state NMR and SAXS studies provide a structural basis for the activation of alphaB-crystallin oligomers
-
Jehle S, Rajagopal P, Bardiaux B, et al. Solid-state NMR and SAXS studies provide a structural basis for the activation of alphaB-crystallin oligomers. Nat Struct Mol Biol 2010;17:1037-42
-
(2010)
Nat Struct Mol Biol
, vol.17
, pp. 1037-1042
-
-
Jehle, S.1
Rajagopal, P.2
Bardiaux, B.3
-
28
-
-
84876065814
-
One size does not fit all: The oligomeric states of alphaB crystallin
-
Delbecq SP, Klevit RE. One size does not fit all: the oligomeric states of alphaB crystallin. FEBS Lett 2013;587:1073-80 . Comprehensive description of the current structural models of aB-crystallin, with a detailed explanation of the hierarchical organization.
-
(2013)
FEBS Lett
, vol.587
, pp. 1073-1080
-
-
Delbecq, S.P.1
Klevit, R.E.2
-
29
-
-
79960698253
-
Three-Dimensional Structure of alpha-Crystallin Domain Dimers of Human Small Heat Shock Proteins HSPB1 and HSPB6
-
Baranova EV, Weeks SD, Beelen S, et al. Three-Dimensional Structure of alpha-Crystallin Domain Dimers of Human Small Heat Shock Proteins HSPB1 and HSPB6. J Mol Biol 2011;411:110-22
-
(2011)
J Mol Biol
, vol.411
, pp. 110-122
-
-
Baranova, E.V.1
Weeks, S.D.2
Beelen, S.3
-
31
-
-
0032077156
-
Genealogy of the alpha-crystallin-small heat-shock protein superfamily
-
De Jong WW, Caspers GJ, Leunissen JA. Genealogy of the alpha-crystallin-small heat-shock protein superfamily. Int J Biol Macromol 1998;22:151-62
-
(1998)
Int J Biol Macromol
, vol.22
, pp. 151-162
-
-
De Jong, W.W.1
Caspers, G.J.2
Leunissen, J.A.3
-
32
-
-
84924126477
-
A First Line of Stress Defense: Small Heat Shock Proteins and their function in protein homeostasis
-
Haslbeck M, Vierling E. A First Line of Stress Defense: Small Heat Shock Proteins and their function in protein homeostasis. J Mol Biol 2015;427(7):1537-48
-
(2015)
J Mol Biol
, vol.427
, Issue.7
, pp. 1537-1548
-
-
Haslbeck, M.1
Vierling, E.2
-
33
-
-
0028903455
-
The expanding small heat-shock protein family and structure predictions of the conserved alpha-crystallin domaiń
-
Caspers GJ, Leunissen JA, De Jong WW. The expanding small heat-shock protein family, and structure predictions of the conserved alpha-crystallin domaiń. J Mol Evol 1995;40:238-48
-
(1995)
J Mol Evol
, vol.40
, pp. 238-248
-
-
Caspers, G.J.1
Leunissen, J.A.2
De Jong, W.W.3
-
34
-
-
70149097520
-
Crystal structures of alpha-crystallin domain dimers of alphaB-crystallin and Hsp20
-
Bagneris C, Bateman OA, Naylor CE, et al. Crystal structures of alpha-crystallin domain dimers of alphaB-crystallin and Hsp20. J Mol Biol 2009;392:1242-52
-
(2009)
J Mol Biol
, vol.392
, pp. 1242-1252
-
-
Bagneris, C.1
Bateman, O.A.2
Naylor, C.E.3
-
35
-
-
79953253901
-
Crystal structure of R120G disease mutant of human alphaB-crystallin domain dimer shows closure of a groove
-
Clark AR, Naylor CE, Bagneris C, et al. Crystal structure of R120G disease mutant of human alphaB-crystallin domain dimer shows closure of a groove. J Mol Biol 2011;408:118-34
-
(2011)
J Mol Biol
, vol.408
, pp. 118-134
-
-
Clark, A.R.1
Naylor, C.E.2
Bagneris, C.3
-
36
-
-
79955597623
-
N-terminal domain of alphaB-crystallin provides a conformational switch for multimerization and structural heterogeneity
-
Jehle S, Vollmar BS, Bardiaux B, et al. N-terminal domain of alphaB-crystallin provides a conformational switch for multimerization and structural heterogeneity. Proc Natl Acad Sci USA 2011;108:6409-14
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 6409-6414
-
-
Jehle, S.1
Vollmar, B.S.2
Bardiaux, B.3
-
37
-
-
84860772345
-
Two decades of studying non-covalent biomolecular assemblies by means of electrospray ionization mass spectrometry
-
Hilton GR, Benesch JL. Two decades of studying non-covalent biomolecular assemblies by means of electrospray ionization mass spectrometry. J R So Interface 2012;9:801-16
-
(2012)
J R so Interface
, vol.9
, pp. 801-816
-
-
Hilton, G.R.1
Benesch, J.L.2
-
38
-
-
84858003372
-
Small heat shock proteins and alpha-crystallins: Dynamic proteins with flexible functions
-
Basha E, O'Neill H, Vierling E. Small heat shock proteins and alpha-crystallins: dynamic proteins with flexible functions. Trends Biochem Sci 2012;37:106-17
-
(2012)
Trends Biochem Sci
, vol.37
, pp. 106-117
-
-
Basha, E.1
O'Neill, H.2
Vierling, E.3
-
39
-
-
84862905389
-
Crystal structure of an activated variant of small heat shock protein Hsp16.5
-
McHaourab HS, Lin YL, Spiller BW. Crystal structure of an activated variant of small heat shock protein Hsp16.5. Biochemistry 2012;51:5105-12
-
(2012)
Biochemistry
, vol.51
, pp. 5105-5112
-
-
McHaourab, H.S.1
Lin, Y.L.2
Spiller, B.W.3
-
40
-
-
84924170601
-
Regulation of the chaperone function of small Hsps
-
Tanguay RM Hightower LE editors. Cham: Springer International Publishing, Switzerland in press
-
Haslbeck M,Weinkauf S, Buchner J. Regulation of the chaperone function of small Hsps. In: Tanguay RM, Hightower LE, editors. The Small HSPWorld. Cham: Springer International Publishing, Switzerland 2015; ISBN: 978-3-319-16076-4; in press
-
(2015)
The Small HSPWorld
-
-
Haslbeck, M.1
Weinkauf, S.2
Buchner, J.3
-
41
-
-
0027391629
-
Small heat shock proteins are molecular chaperones
-
Jakob U, Gaestel M, Engel K, Buchner J. Small heat shock proteins are molecular chaperones. J Biol Chem 1993;268:1517-20
-
(1993)
J Biol Chem
, vol.268
, pp. 1517-1520
-
-
Jakob, U.1
Gaestel, M.2
Engel, K.3
Buchner, J.4
-
42
-
-
0026483279
-
Alpha-crystallin can function as a molecular chaperone
-
Horwitz J. Alpha-crystallin can function as a molecular chaperone. Proc Natl Acad Sci USA 1992;89:10449-53 .. The first study demonstrating the potential of sHsps to suppress the aggregation of substrate proteins.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 10449-10453
-
-
Horwitz, J.1
-
43
-
-
0027472047
-
Evolution of the alpha-crystallin/small heat-shock protein family
-
De Jong WW, Leunissen JA, Voorter CE. Evolution of the alpha-crystallin/small heat-shock protein family. Mol Biol Evol 1993;10:103-26
-
(1993)
Mol Biol Evol
, vol.10
, pp. 103-126
-
-
De Jong, W.W.1
Leunissen, J.A.2
Voorter, C.E.3
-
44
-
-
21244497886
-
Disassembling protein aggregates in the yeast cytosol. The cooperation of Hsp26 with Ssa1 and Hsp104
-
Haslbeck M, Miess A, Stromer T, et al. Disassembling protein aggregates in the yeast cytosol. The cooperation of Hsp26 with Ssa1 and Hsp104. J Biol Chem 2005;280:23861-8
-
(2005)
J Biol Chem
, vol.280
, pp. 23861-23868
-
-
Haslbeck, M.1
Miess, A.2
Stromer, T.3
-
45
-
-
0038043235
-
Analysis of the interaction of small heat shock proteins with unfolding proteins
-
Stromer T, Ehrnsperger M, Gaestel M, Buchner J. Analysis of the interaction of small heat shock proteins with unfolding proteins. J Biol Chem 2003;278:18015-21
-
(2003)
J Biol Chem
, vol.278
, pp. 18015-18021
-
-
Stromer, T.1
Ehrnsperger, M.2
Gaestel, M.3
Buchner, J.4
-
46
-
-
76649084269
-
Quaternary dynamics and plasticity underlie small heat shock protein chaperone function
-
Stengel F, Baldwin AJ, Painter AJ, et al. Quaternary dynamics and plasticity underlie small heat shock protein chaperone function. Proc Natl Acad Sci USA 2010;107:2007-12
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 2007-2012
-
-
Stengel, F.1
Baldwin, A.J.2
Painter, A.J.3
-
47
-
-
0343742639
-
Binding of non-native protein to Hsp25 during heat shock creates a reservoir of folding intermediates for reactivation
-
Ehrnsperger M, Graber S, Gaestel M, Buchner J. Binding of non-native protein to Hsp25 during heat shock creates a reservoir of folding intermediates for reactivation. EMBO J 1997;16:221-9
-
(1997)
EMBO J
, vol.16
, pp. 221-229
-
-
Ehrnsperger, M.1
Graber, S.2
Gaestel, M.3
Buchner, J.4
-
48
-
-
0027999593
-
Cells overexpressing Hsp27 show accelerated recovery from heat-induced nuclear protein aggregation
-
Kampinga HH, Brunsting JF, Stege GJ, et al. Cells overexpressing Hsp27 show accelerated recovery from heat-induced nuclear protein aggregation. Biochem Biophys Res Commun 1994;204:1170-7
-
(1994)
Biochem Biophys Res Commun
, vol.204
, pp. 1170-1177
-
-
Kampinga, H.H.1
Brunsting, J.F.2
Stege, G.J.3
-
49
-
-
0142125283
-
Small heat shock proteins, ClpB and the DnaK system form a functional triade in reversing protein aggregation
-
Mogk A, Deuerling E, Vorderwulbecke S, et al. Small heat shock proteins, ClpB and the DnaK system form a functional triade in reversing protein aggregation. Mol Microbiol 2003;50:585-95
-
(2003)
Mol Microbiol
, vol.50
, pp. 585-595
-
-
Mogk, A.1
Deuerling, E.2
Vorderwulbecke, S.3
-
50
-
-
0031024691
-
A small heat shock protein stably binds heat-denatured model substrates and can maintain a substrate in a folding-competent state
-
Lee GJ, Roseman AM, Saibil HR, Vierling E. A small heat shock protein stably binds heat-denatured model substrates and can maintain a substrate in a folding-competent state. EMBO J 1997;16: 659-71
-
(1997)
EMBO J
, vol.16
, pp. 659-671
-
-
Lee, G.J.1
Roseman, A.M.2
Saibil, H.R.3
Vierling, E.4
-
51
-
-
0032079487
-
The small heat-shock protein IbpB from Escherichia coli stabilizes stress-denatured proteins for subsequent refolding by a multichaperone network
-
Veinger L, Diamant S, Buchner J, Goloubinoff P. The small heat-shock protein IbpB from Escherichia coli stabilizes stress-denatured proteins for subsequent refolding by a multichaperone network. J Biol Chem 1998;273:11032-7
-
(1998)
J Biol Chem
, vol.273
, pp. 11032-11037
-
-
Veinger, L.1
Diamant, S.2
Buchner, J.3
Goloubinoff, P.4
-
52
-
-
1542320089
-
The identity of proteins associated with a small heat shock protein during heat stress in vivo indicates that these chaperones protect a wide range of cellular functions
-
Basha E, Lee GJ, Breci LA, et al. The identity of proteins associated with a small heat shock protein during heat stress in vivo indicates that these chaperones protect a wide range of cellular functions. J Biol Chem 2004;279:7566-75
-
(2004)
J Biol Chem
, vol.279
, pp. 7566-7575
-
-
Basha, E.1
Lee, G.J.2
Breci, L.A.3
-
53
-
-
1442289304
-
Hsp42 is the general small heat shock protein in the cytosol of Saccharomyces cerevisiae
-
Haslbeck M, Braun N, Stromer T, et al. Hsp42 is the general small heat shock protein in the cytosol of Saccharomyces cerevisiae. EMBO J 2004;23:638-49
-
(2004)
EMBO J
, vol.23
, pp. 638-649
-
-
Haslbeck, M.1
Braun, N.2
Stromer, T.3
-
54
-
-
84870917750
-
Alternative bacterial two-component small heat shock protein systems
-
Bepperling A, Alte F, Kriehuber T, et al. Alternative bacterial two-component small heat shock protein systems. Proc Natl Acad Sci USA 2012;109:20407-12
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 20407-20412
-
-
Bepperling, A.1
Alte, F.2
Kriehuber, T.3
-
55
-
-
84887068645
-
In vivo substrate diversity and preference of small heat shock protein IbpB as revealed by using a genetically incorporated photo-cross-linker
-
Fu X, Shi X, Yan L, et al. In vivo substrate diversity and preference of small heat shock protein IbpB as revealed by using a genetically incorporated photo-cross-linker. J Biol Chem 2013;288:31646-54
-
(2013)
J Biol Chem
, vol.288
, pp. 31646-31654
-
-
Fu, X.1
Shi, X.2
Yan, L.3
-
56
-
-
84892390160
-
Identification of proteins that interact with alpha A-crystallin using a human proteome microarray
-
Fan Q, Huang LZ, Zhu XJ, et al. Identification of proteins that interact with alpha A-crystallin using a human proteome microarray. Mol Vis 2014;20:117-24
-
(2014)
Mol Vis
, vol.20
, pp. 117-124
-
-
Fan, Q.1
Huang, L.Z.2
Zhu, X.J.3
-
57
-
-
78650342494
-
Altered chaperone-like activity of alpha-crystallins promotes cataractogensis
-
Cheng C, Xia CH, Huang Q, et al. Altered chaperone-like activity of alpha-crystallins promotes cataractogensis. J Biol Chem 2010;285:41187-93
-
(2010)
J Biol Chem
, vol.285
, pp. 41187-41193
-
-
Cheng, C.1
Xia, C.H.2
Huang, Q.3
-
58
-
-
84899755134
-
In vivo substrates of the lens molecular chaperone alphaA-crystallin and alphaB-crystallin
-
Andley UP, Malone JP, Townsend RR. In vivo substrates of the lens molecular chaperone alphaA-crystallin and alphaB-crystallin. PLoS One 2014;9:e95507
-
(2014)
PLoS One
, vol.9
, pp. e95507
-
-
Andley, U.P.1
Malone, J.P.2
Townsend, R.R.3
-
59
-
-
84893923808
-
HspB1, HspB5 and HspB4 in human cancers: Potent oncogenic role of some of their client proteins
-
Arrigo AP, Gibert P. HspB1, HspB5 and HspB4 in human cancers: potent oncogenic role of some of their client proteins. Cancers 2014;6:333-65
-
(2014)
Cancers
, vol.6
, pp. 333-365
-
-
Arrigo, A.P.1
Gibert, P.2
-
60
-
-
34548305137
-
Binding of caspase-3 prodomain to heat shock protein 27 regulates monocyte apoptosis by inhibiting caspase-3 proteolytic activation
-
Voss OH, Batra S, Kolattukudy SJ, et al. Binding of caspase-3 prodomain to heat shock protein 27 regulates monocyte apoptosis by inhibiting caspase-3 proteolytic activation. J Biol Chem 2007;282:25088-99
-
(2007)
J Biol Chem
, vol.282
, pp. 25088-25099
-
-
Voss, O.H.1
Batra, S.2
Kolattukudy, S.J.3
-
61
-
-
0034643424
-
Hsp27 functions as a negative regulator of cytochrome c-dependent activation of procaspase-3
-
Pandey P, Farber R, Nakazawa A, et al. Hsp27 functions as a negative regulator of cytochrome c-dependent activation of procaspase-3. Oncogene 2000;19:1975-81
-
(2000)
Oncogene
, vol.19
, pp. 1975-1981
-
-
Pandey, P.1
Farber, R.2
Nakazawa, A.3
-
62
-
-
84862939518
-
AlphaA- and alphaB-crystallins interact with caspase-3 and Bax to guard mouse lens development
-
Hu WF, Gong L, Cao Z, et al. alphaA- and alphaB-crystallins interact with caspase-3 and Bax to guard mouse lens development. Curr Mol Med 2012;12: 177-87
-
(2012)
Curr Mol Med
, vol.12
, pp. 177-187
-
-
Hu, W.F.1
Gong, L.2
Cao, Z.3
-
63
-
-
79959964606
-
Apigenin-induced apoptosis of leukemia cells is mediated by a bimodal and differentially regulated residue-specific phosphorylation of heat-shock protein-27
-
Gonzalez-Mejia ME, Voss OH, Murnan EJ, Doseff AI. Apigenin-induced apoptosis of leukemia cells is mediated by a bimodal and differentially regulated residue-specific phosphorylation of heat-shock protein-27. Cell Death Dis 2010;1:e64
-
(2010)
Cell Death Dis
, vol.1
, pp. e64
-
-
Gonzalez-Mejia, M.E.1
Voss, O.H.2
Murnan, E.J.3
Doseff, A.I.4
-
64
-
-
84864492897
-
Small heat shock proteins HSP27 (HspB1), alphaB-crystallin (HspB5) and HSP22 (HspB8) as regulators of cell death
-
Acunzo J, Katsogiannou M, Rocchi P. Small heat shock proteins HSP27 (HspB1), alphaB-crystallin (HspB5) and HSP22 (HspB8) as regulators of cell death. Int J Biochem Cell Biol 2012;44:1622-31
-
(2012)
Int J Biochem Cell Biol
, vol.44
, pp. 1622-1631
-
-
Acunzo, J.1
Katsogiannou, M.2
Rocchi, P.3
-
65
-
-
77950518207
-
Heat shock protein 27 confers resistance to androgen ablation and chemotherapy in prostate cancer cells through eIF4E
-
Andrieu C, Taieb D, Baylot V, et al. Heat shock protein 27 confers resistance to androgen ablation and chemotherapy in prostate cancer cells through eIF4E. Oncogene 2010;29:1883-96
-
(2010)
Oncogene
, vol.29
, pp. 1883-1896
-
-
Andrieu, C.1
Taieb, D.2
Baylot, V.3
-
66
-
-
70350474677
-
Heat shock protein 27 phosphorylation: Kinases, phosphatases, functions and pathology
-
Kostenko S, Moens U. Heat shock protein 27 phosphorylation: kinases, phosphatases, functions and pathology. Cell Mol Life Sci 2009;66:3289-307
-
(2009)
Cell Mol Life Sci
, vol.66
, pp. 3289-3307
-
-
Kostenko, S.1
Moens, U.2
-
67
-
-
4744353967
-
Testis-specific human small heat shock protein HSPB9 is a cancer/testis antigen, and potentially interacts with the dynein subunit TCTEL1
-
de Wit NJ, Verschuure P, Kappe G, et al. Testis-specific human small heat shock protein HSPB9 is a cancer/testis antigen, and potentially interacts with the dynein subunit TCTEL1. Eur J Cell Biol 2004;83: 337-45
-
(2004)
Eur J Cell Biol
, vol.83
, pp. 337-345
-
-
De Wit, N.J.1
Verschuure, P.2
Kappe, G.3
-
68
-
-
84878912425
-
Protein interactomes of three stress inducible small heat shock proteins: HspB1, HspB5 and HspB8
-
Arrigo AP, Gibert B. Protein interactomes of three stress inducible small heat shock proteins: HspB1, HspB5 and HspB8. Int J Hyperthermia 2013;29:409-22
-
(2013)
Int J Hyperthermia
, vol.29
, pp. 409-422
-
-
Arrigo, A.P.1
Gibert, B.2
-
69
-
-
0032818827
-
Intermediate filament interactions can be altered by HSP27 and alphaB-crystallin
-
Perng MD, Cairns L, van den IJssel P, et al. Intermediate filament interactions can be altered by HSP27 and alphaB-crystallin. J Cell Sci 1999;112. Pt 13 2099-112
-
(1999)
J Cell Sci
, vol.112
, pp. 2099-2112
-
-
Perng, M.D.1
Cairns, L.2
Van Den Ijssel, P.3
-
70
-
-
84886003891
-
The small heat shock protein Hsp27 affects assembly dynamics and structure of keratin intermediate filament networks
-
Kayser J, Haslbeck M, Dempfle L, et al. The small heat shock protein Hsp27 affects assembly dynamics and structure of keratin intermediate filament networks. Biophys J 2013;105:1778-85
-
(2013)
Biophys J
, vol.105
, pp. 1778-1785
-
-
Kayser, J.1
Haslbeck, M.2
Dempfle, L.3
-
71
-
-
84904431211
-
Preventing alpha-synuclein aggregation: The role of the small heat-shock molecular chaperone proteins
-
Cox D, Carver JA, Ecroyd H. Preventing alpha-synuclein aggregation: the role of the small heat-shock molecular chaperone proteins. Biochim Biophys Acta 2014;1842: 1830-43
-
(2014)
Biochim Biophys Acta
, vol.1842
, pp. 1830-1843
-
-
Cox, D.1
Carver, J.A.2
Ecroyd, H.3
-
72
-
-
84921340794
-
Small heat-shock proteins: Important players in regulating cellular proteostasis
-
Treweek TM, Meehan S, Ecroyd H, Carver JA. Small heat-shock proteins: important players in regulating cellular proteostasis. Cell Mol Life Sci 2015;72: 429-51
-
(2015)
Cell Mol Life Sci
, vol.72
, pp. 429-451
-
-
Treweek, T.M.1
Meehan, S.2
Ecroyd, H.3
Carver, J.A.4
-
73
-
-
84863683967
-
Small heat shock proteins potentiate amyloid dissolution by protein disaggregases from yeast and humans
-
Duennwald ML, Echeverria A, Shorter J. Small heat shock proteins potentiate amyloid dissolution by protein disaggregases from yeast and humans. PLoS Biol 2012;10:e1001346
-
(2012)
PLoS Biol
, vol.10
, pp. e1001346
-
-
Duennwald, M.L.1
Echeverria, A.2
Shorter, J.3
-
74
-
-
0032546801
-
Identification of 1,1'-bi(4-anilino) naphthalene-5,5'-disulfonic acid binding sequences in alpha-crystallin
-
Sharma KK, Kumar GS, Murphy AS, Kester K. Identification of 1,1'-bi(4-anilino) naphthalene-5,5'-disulfonic acid binding sequences in alpha-crystallin. J Biol Chem 1998;273:15474-8
-
(1998)
J Biol Chem
, vol.273
, pp. 15474-15478
-
-
Sharma, K.K.1
Kumar, G.S.2
Murphy, A.S.3
Kester, K.4
-
75
-
-
34249749409
-
Interactions between important regulatory proteins and human alphaB crystallin
-
Ghosh JG, Shenoy AK Jr, Clark JI. Interactions between important regulatory proteins and human alphaB crystallin. Biochemistry 2007;46:6308-17
-
(2007)
Biochemistry
, vol.46
, pp. 6308-6317
-
-
Ghosh, J.G.1
Shenoy, A.K.2
Clark, J.I.3
-
76
-
-
34250810346
-
Chemical cross-linking of the chloroplast localized small heat-shock protein, Hsp21, and the model substrate citrate synthase
-
Ahrman E, Lambert W, Aquilina JA, et al. Chemical cross-linking of the chloroplast localized small heat-shock protein, Hsp21, and the model substrate citrate synthase. Protein Sci 2007;16:1464-78
-
(2007)
Protein Sci
, vol.16
, pp. 1464-1478
-
-
Ahrman, E.1
Lambert, W.2
Aquilina, J.A.3
-
77
-
-
70349470609
-
Substrate binding site flexibility of the small heat shock protein molecular chaperones
-
Jaya N, Garcia V, Vierling E. Substrate binding site flexibility of the small heat shock protein molecular chaperones. Proc Natl Acad Sci USA 2009;106:15604-9
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 15604-15609
-
-
Jaya, N.1
Garcia, V.2
Vierling, E.3
-
78
-
-
55549133282
-
Insights into small heat shock protein and substrate structure during chaperone action derived from hydrogen/ deuterium exchange and mass spectrometry
-
Cheng G, Basha E, Wysocki VH, Vierling E. Insights into small heat shock protein and substrate structure during chaperone action derived from hydrogen/ deuterium exchange and mass spectrometry. J Biol Chem 2008;283:26634-42
-
(2008)
J Biol Chem
, vol.283
, pp. 26634-26642
-
-
Cheng, G.1
Basha, E.2
Wysocki, V.H.3
Vierling, E.4
-
79
-
-
27744485379
-
Interactive domains for chaperone activity in the small heat shock protein, human alphaB crystallin
-
Ghosh JG, Estrada MR, Clark JI. Interactive domains for chaperone activity in the small heat shock protein, human alphaB crystallin. Biochemistry 2005;44:14854-69
-
(2005)
Biochemistry
, vol.44
, pp. 14854-14869
-
-
Ghosh, J.G.1
Estrada, M.R.2
Clark, J.I.3
-
80
-
-
33644690454
-
Mini-alphaBcrystallin: A functional element of alphaB-crystallin with chaperone-like activity
-
Bhattacharyya J, Padmanabha Udupa EG, Wang J, Sharma KK. Mini-alphaBcrystallin: a functional element of alphaB-crystallin with chaperone-like activity. Biochemistry 2006;45:3069-76
-
(2006)
Biochemistry
, vol.45
, pp. 3069-3076
-
-
Bhattacharyya, J.1
Padmanabha Udupa, E.G.2
Wang, J.3
Sharma, K.K.4
-
81
-
-
84922469706
-
Molecular Mechanism of the Chaperone Function of Mini-alpha- Crystallin, a 19-Residue Peptide of Human alpha-Crystallin
-
Banerjee PR, Pande A, Shekhtman A, Pande J. Molecular Mechanism of the Chaperone Function of Mini-alpha- Crystallin, a 19-Residue Peptide of Human alpha-Crystallin. Biochemistry 2015;54: 505-15
-
(2015)
Biochemistry
, vol.54
, pp. 505-515
-
-
Banerjee, P.R.1
Pande, A.2
Shekhtman, A.3
Pande, J.4
-
82
-
-
78049506985
-
A quantitative NMR spectroscopic examination of the flexibility of the C-terminal extensions of the molecular chaperones, alphaA- and alphaB-crystallin
-
Treweek TM, Rekas A, Walker MJ, Carver JA. A quantitative NMR spectroscopic examination of the flexibility of the C-terminal extensions of the molecular chaperones, alphaA- and alphaB-crystallin. Exp Eye Res 2010;91: 691-9
-
(2010)
Exp Eye Res
, vol.91
, pp. 691-699
-
-
Treweek, T.M.1
Rekas, A.2
Walker, M.J.3
Carver, J.A.4
-
83
-
-
0034486034
-
The function of alpha-crystallin in vision
-
Horwitz J. The function of alpha-crystallin in vision. Semin Cell Dev Biol 2000;11:53
-
(2000)
Semin Cell Dev Biol
, vol.11
, pp. 53
-
-
Horwitz, J.1
-
84
-
-
84655163784
-
Emerging roles of molecular chaperones and co-chaperones in selective autophagy: Focus on BAG proteins
-
Gamerdinger M, Carra S, Behl C. Emerging roles of molecular chaperones and co-chaperones in selective autophagy: focus on BAG proteins. J Mol Med 2011;89: 1175-82 . Summary on the function of sHsps in autophagy explaining the role of the interaction of HSPB8 and BAG3.
-
(2011)
J Mol Med
, vol.89
, pp. 1175-1182
-
-
Gamerdinger, M.1
Carra, S.2
Behl, C.3
-
85
-
-
84907166419
-
BAG3 induces the sequestration of proteasomal clients into cytoplasmic puncta: Implications for a proteasome-to-autophagy switch
-
Minoia M, Boncoraglio A, Vinet J, et al. BAG3 induces the sequestration of proteasomal clients into cytoplasmic puncta: implications for a proteasome-to-autophagy switch. Autophagy 2014;10:1603-21
-
(2014)
Autophagy
, vol.10
, pp. 1603-1621
-
-
Minoia, M.1
Boncoraglio, A.2
Vinet, J.3
-
86
-
-
48849088564
-
Extracellular release of the atheroprotective heat shock protein 27 is mediated by estrogen and competitively inhibits acLDL binding to scavenger receptor-A.
-
Rayner K, Chen YX, McNulty M, et al. Extracellular release of the atheroprotective heat shock protein 27 is mediated by estrogen and competitively inhibits acLDL binding to scavenger receptor-A. Circ Res 2008;103:133-41
-
(2008)
Circ Res
, vol.103
, pp. 133-141
-
-
Rayner, K.1
Chen, Y.X.2
McNulty, M.3
-
87
-
-
24944495594
-
Induction of heat shock proteins in B-cell exosomes
-
Clayton A, Turkes A, Navabi H, et al. Induction of heat shock proteins in B-cell exosomes. J Cell Sci 2005;118:3631-8
-
(2005)
J Cell Sci
, vol.118
, pp. 3631-3638
-
-
Clayton, A.1
Turkes, A.2
Navabi, H.3
-
88
-
-
84864460984
-
The link between small heat shock proteins and the immune system
-
van Noort JM, Bsibsi M, Nacken P, et al. The link between small heat shock proteins and the immune system. Int J Biochem Cell Biol 2012;44:1670-9 . Summarizes the implications of HSPBs in immunology. Explains the anti-inflammatory versus the inflammatory properties of HSPBs.
-
(2012)
Int J Biochem Cell Biol
, vol.44
, pp. 1670-1679
-
-
Van Noort, J.M.1
Bsibsi, M.2
Nacken, P.3
-
89
-
-
77957153127
-
Molecular chaperones and protein-folding catalysts as intercellular signaling regulators in immunity and inflammation
-
Henderson B, Pockley AG. Molecular chaperones and protein-folding catalysts as intercellular signaling regulators in immunity and inflammation. J Leukoc Biol 2010;88:445-62
-
(2010)
J Leukoc Biol
, vol.88
, pp. 445-462
-
-
Henderson, B.1
Pockley, A.G.2
-
90
-
-
84911874159
-
Extracellular cell stress proteins as biomarkers of human disease
-
Pockley AG, Henderson B, Multhoff G. Extracellular cell stress proteins as biomarkers of human disease. Biochemi Soc Trans 2014;42:1744-51
-
(2014)
Biochemi Soc Trans
, vol.42
, pp. 1744-1751
-
-
Pockley, A.G.1
Henderson, B.2
Multhoff, G.3
-
91
-
-
78149428751
-
AlphaB crystallin is apically secreted within exosomes by polarized human retinal pigment epithelium and provides neuroprotection to adjacent cells
-
Sreekumar PG, Kannan R, Kitamura M, et al. alphaB crystallin is apically secreted within exosomes by polarized human retinal pigment epithelium and provides neuroprotection to adjacent cells. PLoS One 2010;5:e12578
-
(2010)
PLoS One
, vol.5
, pp. e12578
-
-
Sreekumar, P.G.1
Kannan, R.2
Kitamura, M.3
-
92
-
-
79952802009
-
AlphaB-crystallin is found in detergent-resistant membrane microdomains and is secreted via exosomes from human retinal pigment epithelial cells
-
Gangalum RK, Atanasov IC, Zhou ZH, Bhat SP. AlphaB-crystallin is found in detergent-resistant membrane microdomains and is secreted via exosomes from human retinal pigment epithelial cells. J Biol Chem 2011;286:3261-9
-
(2011)
J Biol Chem
, vol.286
, pp. 3261-3269
-
-
Gangalum, R.K.1
Atanasov, I.C.2
Zhou, Z.H.3
Bhat, S.P.4
-
93
-
-
84885031543
-
Alpha-B-crystallin induces an immune-regulatory and antiviral microglial response in preactive multiple sclerosis lesions
-
Bsibsi M, Holtman IR, Gerritsen WH, et al. Alpha-B-crystallin induces an immune-regulatory and antiviral microglial response in preactive multiple sclerosis lesions. J Neuropathol Exp Neurol 2013;72: 970-9
-
(2013)
J Neuropathol Exp Neurol
, vol.72
, pp. 970-979
-
-
Bsibsi, M.1
Holtman, I.R.2
Gerritsen, W.H.3
-
94
-
-
80051711544
-
Small heat shock proteins induce a cerebral inflammatory reaction
-
Bruinsma IB, de Jager M, Carrano A, et al. Small heat shock proteins induce a cerebral inflammatory reaction. J Neurosci 2011;31: 11992-2000
-
(2011)
J Neurosci
, vol.31
, pp. 11992-12000
-
-
Bruinsma, I.B.1
De Jager, M.2
Carrano, A.3
-
95
-
-
58149506229
-
Crystallin proteins and amyloid fibrils
-
Ecroyd H, Carver JA. Crystallin proteins and amyloid fibrils. Cell Mol Life Sci 2009;66:62-81
-
(2009)
Cell Mol Life Sci
, vol.66
, pp. 62-81
-
-
Ecroyd, H.1
Carver, J.A.2
-
96
-
-
84855516743
-
The HSPB8-BAG3 chaperone complex is upregulated in astrocytes in the human brain affected by protein aggregation diseases
-
Seidel K, Vinet J, Dunnen WF, et al. The HSPB8-BAG3 chaperone complex is upregulated in astrocytes in the human brain affected by protein aggregation diseases. Neuropathol Appl Neurobiol 2012;38:39-53
-
(2012)
Neuropathol Appl Neurobiol
, vol.38
, pp. 39-53
-
-
Seidel, K.1
Vinet, J.2
Dunnen, W.F.3
-
97
-
-
80053379382
-
Binding of the molecular chaperone alphaB-crystallin to Abeta amyloid fibrils inhibits fibril elongation
-
Shammas SL, Waudby CA, Wang S, et al. Binding of the molecular chaperone alphaB-crystallin to Abeta amyloid fibrils inhibits fibril elongation. Biophys J 2011;101:1681-9
-
(2011)
Biophys J
, vol.101
, pp. 1681-1689
-
-
Shammas, S.L.1
Waudby, C.A.2
Wang, S.3
-
99
-
-
36348935552
-
Clusterin associates with altered elastic fibers in human photoaged skin and prevents elastin from ultraviolet-induced aggregation in vitro
-
Janig E, Haslbeck M, Aigelsreiter A, et al. Clusterin associates with altered elastic fibers in human photoaged skin and prevents elastin from ultraviolet-induced aggregation in vitro. Am J Pathol 2007;171:1474-82
-
(2007)
Am J Pathol
, vol.171
, pp. 1474-1482
-
-
Janig, E.1
Haslbeck, M.2
Aigelsreiter, A.3
-
100
-
-
0037007283
-
Molecular chaperones-cellular machines for protein folding
-
Walter S, Buchner J. Molecular chaperones-cellular machines for protein folding. Angew Chem Int Ed Engl 2002;41: 1098-113
-
(2002)
Angew Chem Int Ed Engl
, vol.41
, pp. 1098-1113
-
-
Walter, S.1
Buchner, J.2
-
101
-
-
66149117827
-
Structure and mechanism of protein stability sensors: Chaperone activity of small heat shock proteins
-
McHaourab HS, Godar JA, Stewart PL. Structure and mechanism of protein stability sensors: chaperone activity of small heat shock proteins. Biochemistry 2009;48: 3828-37
-
(2009)
Biochemistry
, vol.48
, pp. 3828-3837
-
-
McHaourab, H.S.1
Godar, J.A.2
Stewart, P.L.3
-
102
-
-
77951228945
-
Mechanistic differences between two conserved classes of small heat shock proteins found in the plant cytosol
-
Basha E, Jones C, Wysocki V, Vierling E. Mechanistic differences between two conserved classes of small heat shock proteins found in the plant cytosol. J Biol Chem 2010;285:11489-97
-
(2010)
J Biol Chem
, vol.285
, pp. 11489-11497
-
-
Basha, E.1
Jones, C.2
Wysocki, V.3
Vierling, E.4
-
103
-
-
17644408766
-
Subunit exchange of polydisperse proteins: Mass spectrometry reveals consequences of alphaA-crystallin truncation
-
Aquilina JA, Benesch JL, Ding LL, et al. Subunit exchange of polydisperse proteins: mass spectrometry reveals consequences of alphaA-crystallin truncation. J Biol Chem 2005;280:14485-91
-
(2005)
J Biol Chem
, vol.280
, pp. 14485-14491
-
-
Aquilina, J.A.1
Benesch, J.L.2
Ding, L.L.3
-
104
-
-
84874101818
-
Cryoelectron microscopy analysis of small heat shock protein 16.5 (Hsp16.5) complexes with T4 lysozyme reveals the structural basis of multimode binding
-
Shi J, Koteiche HA, McDonald ET, et al. Cryoelectron microscopy analysis of small heat shock protein 16.5 (Hsp16.5) complexes with T4 lysozyme reveals the structural basis of multimode binding. J Biol Chem 2013;288:4819-30
-
(2013)
J Biol Chem
, vol.288
, pp. 4819-4830
-
-
Shi, J.1
Koteiche, H.A.2
McDonald, E.T.3
-
105
-
-
0032077176
-
Phosphorylations of alpha A- and alpha B-crystallin
-
Kantorow M, Piatigorsky J. Phosphorylations of alpha A- and alpha B-crystallin. Int J Biol Macromol 1998;22: 307-14
-
(1998)
Int J Biol Macromol
, vol.22
, pp. 307-314
-
-
Kantorow, M.1
Piatigorsky, J.2
-
106
-
-
0036372749
-
SHsp-phosphorylation: Enzymes, signaling pathways and functional implications
-
Gaestel M. sHsp-phosphorylation: enzymes, signaling pathways and functional implications. Prog Mol Subcell Biol 2002;28:151-69
-
(2002)
Prog Mol Subcell Biol
, vol.28
, pp. 151-169
-
-
Gaestel, M.1
-
107
-
-
0032986520
-
Harding JJ. A-crystallin as a molecular chaperone
-
Derham BK, Harding JJ. a-crystallin as a molecular chaperone. Prog Retin Eye Res 1999;18:463-509
-
(1999)
Prog Retin Eye Res
, vol.18
, pp. 463-509
-
-
Derham, B.K.1
-
108
-
-
84929597659
-
-
Uniport. Available from: www.uniprot.org
-
-
-
-
109
-
-
0035820325
-
In vitro dephosphorylation of a-crystallin is dependent on the state of oligomerization
-
Moroni M, Garland D. In vitro dephosphorylation of a-crystallin is dependent on the state of oligomerization. Biochim Biophys Acta 2001;1546:282-90
-
(2001)
Biochim Biophys Acta
, vol.1546
, pp. 282-290
-
-
Moroni, M.1
Garland, D.2
-
110
-
-
67650547950
-
Phosphorylation dependence of hsp27 multimeric size and molecular chaperone function
-
Hayes D, Napoli V, Mazurkie A, et al. Phosphorylation dependence of hsp27 multimeric size and molecular chaperone function. J Biol Chem 2009;284: 18801-7
-
(2009)
J Biol Chem
, vol.284
, pp. 18801-18807
-
-
Hayes, D.1
Napoli, V.2
Mazurkie, A.3
-
111
-
-
0033516660
-
Regulation of Hsp27 oligomerization, chaperone function, and protective activity against oxidative stress/tumor necrosis factor a by phosphorylation
-
Rogalla T, Ehrnsperger M, Preville X, et al. Regulation of Hsp27 oligomerization, chaperone function, and protective activity against oxidative stress/tumor necrosis factor a by phosphorylation. J Biol Chem 1999;274:18947-56
-
(1999)
J Biol Chem
, vol.274
, pp. 18947-18956
-
-
Rogalla, T.1
Ehrnsperger, M.2
Preville, X.3
-
112
-
-
7244227985
-
Deamidation affects structural and functional properties of human alphaA-crystallin and its oligomerization with alphaB-crystallin
-
Gupta R, Srivastava OP. Deamidation affects structural and functional properties of human alphaA-crystallin and its oligomerization with alphaB-crystallin. J Biol Chem 2004;279:44258-69
-
(2004)
J Biol Chem
, vol.279
, pp. 44258-44269
-
-
Gupta, R.1
Srivastava, O.P.2
-
113
-
-
4544223824
-
Enhanced degradation and decreased stability of eye lens alpha-crystallin upon methylglyoxal modification
-
Satish Kumar M, Mrudula T, Mitra N, Bhanuprakash Reddy G. Enhanced degradation and decreased stability of eye lens alpha-crystallin upon methylglyoxal modification. Exp Eye Res 2004;79:577-83
-
(2004)
Exp Eye Res
, vol.79
, pp. 577-583
-
-
Satish Kumar, M.1
Mrudula, T.2
Mitra, N.3
Bhanuprakash Reddy, G.4
-
114
-
-
0035951292
-
Oxidation of human lens recombinant alphaA-crystallin and cysteine-deficient mutants
-
Chen SJ, Sun TX, Akhtar NJ, Liang JJ. Oxidation of human lens recombinant alphaA-crystallin and cysteine-deficient mutants. J Mol Biol 2001;305:969-76
-
(2001)
J Mol Biol
, vol.305
, pp. 969-976
-
-
Chen, S.J.1
Sun, T.X.2
Akhtar, N.J.3
Liang, J.J.4
-
115
-
-
84939887279
-
Effect of disulfide crosslinking on thermal transitions and chaperone-like activity of human small heat shock protein HspB1
-
Chalova AS, Sudnitsyna MV, Semenyuk PI, et al. Effect of disulfide crosslinking on thermal transitions and chaperone-like activity of human small heat shock protein HspB1. Cell Stress Chaperones 2014;19: 963-72
-
(2014)
Cell Stress Chaperones
, vol.19
, pp. 963-972
-
-
Chalova, A.S.1
Sudnitsyna, M.V.2
Semenyuk, P.I.3
-
116
-
-
0037077277
-
S-thiolation of HSP27 regulates its multimeric aggregate size independently of phosphorylation
-
Eaton P, Fuller W, Shattock MJ. S-thiolation of HSP27 regulates its multimeric aggregate size independently of phosphorylation. J Biol Chem 2002;277: 21189-96
-
(2002)
J Biol Chem
, vol.277
, pp. 21189-21196
-
-
Eaton, P.1
Fuller, W.2
Shattock, M.J.3
-
117
-
-
33748087444
-
Effect of methylglyoxal modification and phosphorylation on the chaperone and anti-apoptotic properties of heat shock protein 27
-
Oya-Ito T, Liu BF, Nagaraj RH. Effect of methylglyoxal modification and phosphorylation on the chaperone and anti-apoptotic properties of heat shock protein 27. J Cell Biochem 2006;99:279-91
-
(2006)
J Cell Biochem
, vol.99
, pp. 279-291
-
-
Oya-Ito, T.1
Liu, B.F.2
Nagaraj, R.H.3
-
118
-
-
50149109874
-
Selective Cu2+ binding, redox silencing, and cytoprotective effects of the small heat shock proteins alphaA- and alphaB-crystallin
-
Ahmad MF, Singh D, Taiyab A, et al. Selective Cu2+ binding, redox silencing, and cytoprotective effects of the small heat shock proteins alphaA- and alphaB-crystallin. J Mol Biol 2008;382:812-24
-
(2008)
J Mol Biol
, vol.382
, pp. 812-824
-
-
Ahmad, M.F.1
Singh, D.2
Taiyab, A.3
-
119
-
-
84855478926
-
Structural and mechanistic implications of metal binding in the small heat-shock protein alphaB-crystallin
-
Mainz A, Bardiaux B, Kuppler F, et al. Structural and mechanistic implications of metal binding in the small heat-shock protein alphaB-crystallin. J Biol Chem 2012;287:1128-38
-
(2012)
J Biol Chem
, vol.287
, pp. 1128-1138
-
-
Mainz, A.1
Bardiaux, B.2
Kuppler, F.3
-
120
-
-
0032077161
-
The effect of the intersubunit disulfide bond on the structural and functional properties of the small heat shock protein Hsp25
-
Zavialov A, Benndorf R, Ehrnsperger M, et al. The effect of the intersubunit disulfide bond on the structural and functional properties of the small heat shock protein Hsp25. Int J Biol Macromol 1998;22: 163-73
-
(1998)
Int J Biol Macromol
, vol.22
, pp. 163-173
-
-
Zavialov, A.1
Benndorf, R.2
Ehrnsperger, M.3
-
121
-
-
84934439863
-
The cellular "networking" of mammalian Hsp27 and its functions in the control of protein folding, redox state and apoptosis
-
Arrigo AP. The cellular "networking" of mammalian Hsp27 and its functions in the control of protein folding, redox state and apoptosis. Adv Exp Med Biol 2007;594: 14-26
-
(2007)
Adv Exp Med Biol
, vol.594
, pp. 14-26
-
-
Arrigo, A.P.1
-
122
-
-
79959506144
-
The anti-apoptotic function of human alphaA-crystallin is directly related to its chaperone activity
-
Pasupuleti N, Matsuyama S, Voss O, et al. The anti-apoptotic function of human alphaA-crystallin is directly related to its chaperone activity. Cell Death Dis 2010;1: e31
-
(2010)
Cell Death Dis
, vol.1
, pp. e31
-
-
Pasupuleti, N.1
Matsuyama, S.2
Voss, O.3
-
123
-
-
84864437102
-
Small heat shock proteins in redox metabolism: Implications for cardiovascular diseases
-
Christians ES, Ishiwata T, Benjamin IJ. Small heat shock proteins in redox metabolism: implications for cardiovascular diseases. Int J Biochem Cell Biol 2012;44: 1632-45
-
(2012)
Int J Biochem Cell Biol
, vol.44
, pp. 1632-1645
-
-
Christians, E.S.1
Ishiwata, T.2
Benjamin, I.J.3
-
124
-
-
0032807869
-
Lens alpha-crystallin: Function and structure
-
Horwitz J, Bova MP, Ding LL, et al. Lens alpha-crystallin: function and structure. Eye 1999;13(Pt 3b):403-8
-
(1999)
Eye
, vol.13
, pp. 403-408
-
-
Horwitz, J.1
Bova, M.P.2
Ding, L.L.3
-
125
-
-
0033984092
-
Muscle develops a specific form of small heat shock protein complex composed of MKBP/HSPB2 and HSPB3 during myogenic differentiation
-
Sugiyama Y, Suzuki A, Kishikawa M, et al. Muscle develops a specific form of small heat shock protein complex composed of MKBP/HSPB2 and HSPB3 during myogenic differentiation. J Biol Chem 2000;275:1095-104
-
(2000)
J Biol Chem
, vol.275
, pp. 1095-1104
-
-
Sugiyama, Y.1
Suzuki, A.2
Kishikawa, M.3
-
126
-
-
26844557815
-
Interactions of HSP22 (HSPB8) with HSP20, alphaB-crystallin, and HSPB3
-
Fontaine JM, Sun X, Benndorf R, Welsh MJ. Interactions of HSP22 (HSPB8) with HSP20, alphaB-crystallin, and HSPB3. Biochem Biophys Res Commun 2005;337: 1006-11
-
(2005)
Biochem Biophys Res Commun
, vol.337
, pp. 1006-1011
-
-
Fontaine, J.M.1
Sun, X.2
Benndorf, R.3
Welsh, M.J.4
-
127
-
-
1342334759
-
Interaction of human HSP22 (HSPB8) with other small heat shock proteins
-
Sun XK, Fontaine JM, Rest JS, et al. Interaction of human HSP22 (HSPB8) with other small heat shock proteins. J Biol Chem 2004;279:2394-402
-
(2004)
J Biol Chem
, vol.279
, pp. 2394-2402
-
-
Sun, X.K.1
Fontaine, J.M.2
Rest, J.S.3
-
128
-
-
84876707777
-
The chaperone Hsp90: Changing partners for demanding clients
-
Rohl A, Rohrberg J, Buchner J. The chaperone Hsp90: changing partners for demanding clients. Trends Biochem Sci 2013;38:253-62
-
(2013)
Trends Biochem Sci
, vol.38
, pp. 253-262
-
-
Rohl, A.1
Rohrberg, J.2
Buchner, J.3
-
129
-
-
84868142926
-
Pharmacological tuning of heat shock protein 70 modulates polyglutamine toxicity and aggregation
-
Chafekar SM, Wisen S, Thompson AD, et al. Pharmacological tuning of heat shock protein 70 modulates polyglutamine toxicity and aggregation. ACS Chem Biol 2012;7: 1556-64
-
(2012)
ACS Chem Biol
, vol.7
, pp. 1556-1564
-
-
Chafekar, S.M.1
Wisen, S.2
Thompson, A.D.3
-
130
-
-
84899005317
-
High-throughput screen of natural product extracts in a yeast model of polyglutamine proteotoxicity
-
Walter GM, Raveh A, Mok SA, et al. High-throughput screen of natural product extracts in a yeast model of polyglutamine proteotoxicity. Chem Biol Drug Des 2014;83:440-9
-
(2014)
Chem Biol Drug des
, vol.83
, pp. 440-449
-
-
Walter, G.M.1
Raveh, A.2
Mok, S.A.3
-
131
-
-
80052049395
-
Inhibition of heat shock protein 27 (HspB1) tumorigenic functions by peptide aptamers
-
Gibert B, Hadchity E, Czekalla A, et al. Inhibition of heat shock protein 27 (HspB1) tumorigenic functions by peptide aptamers. Oncogene 2011;30:3672-81
-
(2011)
Oncogene
, vol.30
, pp. 3672-3681
-
-
Gibert, B.1
Hadchity, E.2
Czekalla, A.3
-
132
-
-
84929597660
-
Validation of the Hsp70-Bag3 protein-protein interaction as a potential therapeutic target in cancer
-
[Epub ahead of print]
-
Li X, Colvin T, Rauch JN, et al. Validation of the Hsp70-Bag3 protein-protein interaction as a potential therapeutic target in cancer. Mol Cancer Ther 2015. [Epub ahead of print]
-
(2015)
Mol Cancer Ther
-
-
Li, X.1
Colvin, T.2
Rauch, J.N.3
-
134
-
-
25844466597
-
Heat shock response modulators as therapeutic tools for diseases of protein conformation
-
Westerheide SD, Morimoto RI. Heat shock response modulators as therapeutic tools for diseases of protein conformation. J Biol Chem 2005;280:33097-100
-
(2005)
J Biol Chem
, vol.280
, pp. 33097-33100
-
-
Westerheide, S.D.1
Morimoto, R.I.2
-
135
-
-
0026755773
-
Inhibition of the activation of heat shock factor in vivo and in vitro by flavonoids
-
Hosokawa N, Hirayoshi K, Kudo H, et al. Inhibition of the activation of heat shock factor in vivo and in vitro by flavonoids. Mol Cell Biol 1992;12:3490-8
-
(1992)
Mol Cell Biol
, vol.12
, pp. 3490-3498
-
-
Hosokawa, N.1
Hirayoshi, K.2
Kudo, H.3
-
136
-
-
0030038266
-
Geranylgeranylacetone induces heat shock proteins in cultured guinea pig gastric mucosal cells and rat gastric mucosa
-
Hirakawa T, Rokutan K, Nikawa T, Kishi K. Geranylgeranylacetone induces heat shock proteins in cultured guinea pig gastric mucosal cells and rat gastric mucosa. Gastroenterology 1996;111:345-57
-
(1996)
Gastroenterology
, vol.111
, pp. 345-357
-
-
Hirakawa, T.1
Rokutan, K.2
Nikawa, T.3
Kishi, K.4
-
137
-
-
79956311279
-
The novel hydroxylamine derivative NG-094 suppresses polyglutamine protein toxicity in Caenorhabditis elegans
-
Haldimann P, Muriset M, Vigh L, Goloubinoff P. The novel hydroxylamine derivative NG-094 suppresses polyglutamine protein toxicity in Caenorhabditis elegans. J Biol Chem 2011;286:18784-94
-
(2011)
J Biol Chem
, vol.286
, pp. 18784-18794
-
-
Haldimann, P.1
Muriset, M.2
Vigh, L.3
Goloubinoff, P.4
-
138
-
-
84897939278
-
Barcoding heat shock proteins to human diseases: Looking beyond the heat shock response
-
Kakkar V, Meister-Broekema M, Minoia M, et al. Barcoding heat shock proteins to human diseases: looking beyond the heat shock response. Dis Model Mech 2014;7: 421-34
-
(2014)
Dis Model Mech
, vol.7
, pp. 421-434
-
-
Kakkar, V.1
Meister-Broekema, M.2
Minoia, M.3
-
139
-
-
84924908864
-
Targeting heat shock proteins in metastatic castration-resistant prostate cancer
-
Azad AA, Zoubeidi A, Gleave ME, Chi KN. Targeting heat shock proteins in metastatic castration-resistant prostate cancer. Nature Rev Urol 2015;12:26-36
-
(2015)
Nature Rev Urol
, vol.12
, pp. 26-36
-
-
Azad, A.A.1
Zoubeidi, A.2
Gleave, M.E.3
Chi, K.N.4
-
140
-
-
84864462281
-
Small heat shock proteins in cancer therapy and prognosis
-
Zoubeidi A, Gleave M. Small heat shock proteins in cancer therapy and prognosis. Int J Biochem Cell Biol 2012;44:1646-56
-
(2012)
Int J Biochem Cell Biol
, vol.44
, pp. 1646-1656
-
-
Zoubeidi, A.1
Gleave, M.2
-
141
-
-
70350537407
-
HSP27: Mechanisms of cellular protection against neuronal injury
-
Stetler RA, Gao Y, Signore AP, et al. HSP27: mechanisms of cellular protection against neuronal injury. Curr Mol Med 2009;9:863-72
-
(2009)
Curr Mol Med
, vol.9
, pp. 863-872
-
-
Stetler, R.A.1
Gao, Y.2
Signore, A.P.3
-
142
-
-
34547152612
-
Protective and therapeutic role for alphaB-crystallin in autoimmune demyelination
-
Ousman SS, Tomooka BH, van Noort JM, et al. Protective and therapeutic role for alphaB-crystallin in autoimmune demyelination. Nature 2007;448:474-9
-
(2007)
Nature
, vol.448
, pp. 474-479
-
-
Ousman, S.S.1
Tomooka, B.H.2
Van Noort, J.M.3
|