Cryoelectron microscopy analysis of small heat shock protein 16.5 (Hsp16.5) complexes with T4 lysozyme reveals the structural basis of multimode binding

Journal of Biological Chemistry

Volumn 288, Issue 7, 2013, Pages 4819-4830

  Shi, Jian ^a   Koteiche, Hanane A ^a   McDonald, Ezelle T ^a   Fox, Tara L ^a,b   Stewart, Phoebe L ^a,b   Mchaourab, Hassane S ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CRYO-ELECTRON MICROSCOPY; HIGH AFFINITY BINDING; MULTIMODES; MULTIPLE MODES; N-TERMINALS; NON-NATIVE; SMALL HEAT SHOCK PROTEINS; STRUCTURAL BASIS; STRUCTURAL CHANGE; SUBSTRATE BINDING; T4 LYSOZYME;

IMAGE RECONSTRUCTION; OLIGOMERS;

GENE ENCODING;

ALPHA CRYSTALLIN; LYSOZYME; OLIGOMER; SMALL HEAT SHOCK PROTEIN; SMALL HEAT SHOCK PROTEIN 16.5; T4 LYSOZYME; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; BINDING SITE; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYOELECTRON MICROSCOPY; HYDRODYNAMICS; MOLECULAR IMAGING; MOLECULAR RECOGNITION; MUTANT; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN ASSEMBLY; PROTEIN BINDING; PROTEIN MODIFICATION; PROTEIN PROTEIN INTERACTION; STRUCTURE ANALYSIS; WILD TYPE;

ALPHA-CRYSTALLINS; ARCHAEAL PROTEINS; BACTERIOPHAGE T4; CLONING, MOLECULAR; CRYOELECTRON MICROSCOPY; HEAT-SHOCK PROTEINS; IMAGE PROCESSING, COMPUTER-ASSISTED; MODELS, MOLECULAR; MOLECULAR CHAPERONES; MOLECULAR CONFORMATION; MURAMIDASE; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; SUBSTRATE SPECIFICITY; TEMPERATURE;

EID: 84874101818     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.388132     Document Type: Article

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