The anti-apoptotic function of human αA-crystallin is directly related to its chaperone activity

Cell Death and Disease

Volumn 1, Issue 3, 2010, Pages

  Pasupuleti, N ^a   Matsuyama, S ^a   Voss, O ^b   Doseff, A I ^b   Song, K ^a   Danielpour, D ^a   Nagaraj, R H ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b OHIO STATE UNIVERSITY   (United States)

Author keywords

Apoptosis; Chaperone; Crystalline; PI3K; PTEN

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ALPHA CRYSTALLIN; BIM PROTEIN; CASPASE 3; CASPASE 9; CHAPERONE; CYTOCHROME C; DOXORUBICIN; MUTANT PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1; PROCASPASE 3; PROTEIN BAX; PROTEIN KINASE B; TENSIN; APOPTOSIS REGULATORY PROTEIN; BCL 2 LIKE PROTEIN 11; BCL-2-LIKE PROTEIN 11; CRYAA PROTEIN, HUMAN; CRYSTALLIN; ENZYME INHIBITOR; MEMBRANE PROTEIN; ONCOPROTEIN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN SERINE THREONINE KINASE; PTEN PROTEIN, HUMAN; PYRUVATE DEHYDROGENASE (ACETYL TRANSFERRING) KINASE; PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING) KINASE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL SURVIVAL; CHO CELL; DOWN REGULATION; ENZYME ACTIVITY; ENZYME INHIBITION; HELA CELL; HUMAN; HUMAN CELL; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; WILD TYPE; ANIMAL; CRICETULUS; DRUG ANTAGONISM; ENZYME ACTIVATION; GENETICS; HAMSTER; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN TRANSPORT;

CRICETULUS GRISEUS;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CASPASE 9; CHO CELLS; CRICETINAE; CRICETULUS; CRYSTALLINS; CYTOCHROMES C; DOXORUBICIN; ENZYME ACTIVATION; ENZYME INHIBITORS; HELA CELLS; HUMANS; MEMBRANE PROTEINS; MITOCHONDRIA; PHOSPHATIDYLINOSITOL 3-KINASE; PHOSPHORYLATION; PROTEIN TRANSPORT; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE;

EID: 79959506144     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2010.3     Document Type: Article

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