-
1
-
-
47949099098
-
Origin and physiological roles of inflammation
-
Medzhitov R (2008) Origin and physiological roles of inflammation. Nature 454(7203): 428-435
-
(2008)
Nature
, vol.454
, Issue.7203
, pp. 428-435
-
-
Medzhitov, R.1
-
2
-
-
84861199459
-
Sepsis: Something old, something new, and a systems view
-
Namas R, Zamora R, Namas R, An G, Doyle J, Dick TE et al (2012) Sepsis: something old, something new, and a systems view. J Crit Care 27:314.e1-314.e11
-
(2012)
J Crit Care
, vol.27
, pp. 314e1-314e11
-
-
Namas, R.1
Zamora, R.2
Namas, R.3
An, G.4
Doyle, J.5
Dick, T.E.6
-
3
-
-
75149172745
-
The acute inflammatory response in trauma/hemorrhage and traumatic brain injury: Current state and emerging prospects
-
Namas R, Ghuma A, Hermus L, Zamora R, Okonkwo DO, Billiar TR et al (2009) The acute inflammatory response in trauma/hemorrhage and traumatic brain injury: current state and emerging prospects. Libyan J Med 4:136-148
-
(2009)
Libyan J Med
, vol.4
, pp. 136-148
-
-
Namas, R.1
Ghuma, A.2
Hermus, L.3
Zamora, R.4
Okonkwo, D.O.5
Billiar, T.R.6
-
4
-
-
0034919862
-
Inflammation, coagulopathy, and the pathogenesis of multiple organ dysfunction syndrome
-
Marshall JC (2001) Inflammation, coagulopathy, and the pathogenesis of multiple organ dysfunction syndrome. Crit Care Med 29(7 Suppl):S99-S106
-
(2001)
Crit Care Med
, vol.29
, Issue.7
, pp. S99-S106
-
-
Marshall, J.C.1
-
5
-
-
0033258418
-
Organ dysfunction following hemorrhage and sepsis: Mechanisms and therapeutic approaches (Review)
-
Jarrar D, Chaudry IH, Wang P (1999) Organ dysfunction following hemorrhage and sepsis: mechanisms and therapeutic approaches (Review). Int J Mol Med 4(6):575-583
-
(1999)
Int J Mol Med
, vol.4
, Issue.6
, pp. 575-583
-
-
Jarrar, D.1
Chaudry, I.H.2
Wang, P.3
-
6
-
-
43249089766
-
Translational systems biology of inflammation
-
Vodovotz Y, Csete M, Bartels J, Chang S, An G (2008) Translational systems biology of inflammation. PLoS Comput Biol 4:1-6
-
(2008)
PLoS Comput Biol
, vol.4
, pp. 1-6
-
-
Vodovotz, Y.1
Csete, M.2
Bartels, J.3
Chang, S.4
An, G.5
-
8
-
-
74549170381
-
Translational systems biology of inflammation and healing
-
Vodovotz Y (2010) Translational systems biology of inflammation and healing. Wound Repair Regen 18(1):3-7
-
(2010)
Wound Repair Regen
, vol.18
, Issue.1
, pp. 3-7
-
-
Vodovotz, Y.1
-
9
-
-
0029942245
-
Shock: Ischemia, reperfusion, and inflammation
-
Waxman K (1996) Shock: ischemia, reperfusion, and inflammation. New Horiz 4(2):153-160
-
(1996)
New Horiz
, vol.4
, Issue.2
, pp. 153-160
-
-
Waxman, K.1
-
10
-
-
0029410635
-
Hemorrhagic shock
-
Peitzman AB, Billiar TR, Harbrecht BG, Kelly E, Udekwu AO, Simmons RL (1995) Hemorrhagic shock. Curr Probl Surg 32(11):925-1002
-
(1995)
Curr Probl Surg
, vol.32
, Issue.11
, pp. 925-1002
-
-
Peitzman, A.B.1
Billiar, T.R.2
Harbrecht, B.G.3
Kelly, E.4
Udekwu, A.O.5
Simmons, R.L.6
-
11
-
-
77949531330
-
An adequately robust early TNF-a response is a hallmark of survival following trauma/hemorrhage
-
Namas R, Ghuma A, Torres A, Polanco P, Gomez H, Barclay D et al (2009) An adequately robust early TNF-a response is a hallmark of survival following trauma/hemorrhage. PLoS One 4(12):e8406
-
(2009)
PLoS One
, vol.4
, Issue.12
, pp. e8406
-
-
Namas, R.1
Ghuma, A.2
Torres, A.3
Polanco, P.4
Gomez, H.5
Barclay, D.6
-
12
-
-
0037180812
-
Points of control in inflammation
-
Nathan C (2002) Points of control in inflammation. Nature 420(6917):846-852
-
(2002)
Nature
, vol.420
, Issue.6917
, pp. 846-852
-
-
Nathan, C.1
-
13
-
-
79955904927
-
A dynamic view of trauma/hemorrhage-induced inflammation in mice: Principal drivers and networks
-
Mi Q, Constantine G, Ziraldo C, Solovyev A, Torres A, Namas R et al (2011) A dynamic view of trauma/hemorrhage-induced inflammation in mice: principal drivers and networks. PLoS One 6:e19424
-
(2011)
PLoS One
, vol.6
, pp. e19424
-
-
Mi, Q.1
Constantine, G.2
Ziraldo, C.3
Solovyev, A.4
Torres, A.5
Namas, R.6
-
14
-
-
21744440089
-
The acute inflammatory response in diverse shock states
-
Chow CC, Clermont G, Kumar R, Lagoa C, Tawadrous Z, Gallo D et al (2005) The acute inflammatory response in diverse shock states. Shock 24:74-84
-
(2005)
Shock
, vol.24
, pp. 74-84
-
-
Chow, C.C.1
Clermont, G.2
Kumar, R.3
Lagoa, C.4
Tawadrous, Z.5
Gallo, D.6
-
15
-
-
33751222859
-
The role of initial trauma in the host's response to injury and hemorrhage: Insights from a comparison of mathematical simulations and hepatic transcriptomic analysis
-
Lagoa CE, Bartels J, Baratt A, Tseng G, Clermont G, Fink MP et al (2006) The role of initial trauma in the host's response to injury and hemorrhage: insights from a comparison of mathematical simulations and hepatic transcriptomic analysis. Shock 26:592-600
-
(2006)
Shock
, vol.26
, pp. 592-600
-
-
Lagoa, C.E.1
Bartels, J.2
Baratt, A.3
Tseng, G.4
Clermont, G.5
Fink, M.P.6
-
16
-
-
33747106908
-
A reduced mathematical model of the acute inflammatory response: I. Derivation of model and analysis of anti-inflammation
-
Reynolds A, Rubin J, Clermont G, Day J, Vodovotz Y, Bard Ermentrout G (2006) A reduced mathematical model of the acute inflammatory response: I. Derivation of model and analysis of anti-inflammation. J Theor Biol 242(1):220-236
-
(2006)
J Theor Biol
, vol.242
, Issue.1
, pp. 220-236
-
-
Reynolds, A.1
Rubin, J.2
Clermont, G.3
Day, J.4
Vodovotz, Y.5
Bard Ermentrout, G.6
-
17
-
-
67749139592
-
Mathematical modeling of post-hemorrhage inflammation in mice: Studies using a novel, computer-controlled, closed-loop hemorrhage apparatus
-
Torres A, Bentley T, Bartels J, Sarkar J, Barclay D, Namas R et al (2009) Mathematical modeling of post-hemorrhage inflammation in mice: studies using a novel, computer-controlled, closed-loop hemorrhage apparatus. Shock 32(2):172-178
-
(2009)
Shock
, vol.32
, Issue.2
, pp. 172-178
-
-
Torres, A.1
Bentley, T.2
Bartels, J.3
Sarkar, J.4
Barclay, D.5
Namas, R.6
-
18
-
-
77957580213
-
Translational systems biology of inflammation: Potential applications to personalized medicine
-
Mi Q, Li NYK, Ziraldo C, Ghuma A, Mikheev M, Squires R et al (2010) Translational systems biology of inflammation: potential applications to personalized medicine. Per Med 7:549-559
-
(2010)
Per Med
, vol.7
, pp. 549-559
-
-
Mi, Q.1
Li, N.Y.K.2
Ziraldo, C.3
Ghuma, A.4
Mikheev, M.5
Squires, R.6
-
19
-
-
78649526394
-
Sterile inflammation: Sensing and reacting to damage
-
Chen GY, Nuñez G (2010) Sterile inflammation: sensing and reacting to damage. Nat Rev Immunol 10(12):826-837
-
(2010)
Nat Rev Immunol
, vol.10
, Issue.12
, pp. 826-837
-
-
Chen, G.Y.1
Nuñez, G.2
-
20
-
-
0024950718
-
Tumour necrosis factor: Clinical relevance
-
Jones AL, Selby P (1989) Tumour necrosis factor: clinical relevance. Cancer Surv 8(4):817-836
-
(1989)
Cancer Surv
, vol.8
, Issue.4
, pp. 817-836
-
-
Jones, A.L.1
Selby, P.2
-
21
-
-
0028579731
-
Cytokines and macrophages
-
Cavaillon JM (1994) Cytokines and macrophages. Biomed Pharmacother 48(10):445-453
-
(1994)
Biomed Pharmacother
, vol.48
, Issue.10
, pp. 445-453
-
-
Cavaillon, J.M.1
-
23
-
-
0033874108
-
Proinflammatory cytokines
-
Dinarello CA (2000) Proinflammatory cytokines. Chest 118(2):503-508
-
(2000)
Chest
, vol.118
, Issue.2
, pp. 503-508
-
-
Dinarello, C.A.1
-
24
-
-
0035532701
-
Sepsis: A pro- and anti-inflammatory disequilibrium syndrome
-
Pinsky MR (2001) Sepsis: a pro- and anti-inflammatory disequilibrium syndrome. Contrib Nephrol 132:354-366
-
(2001)
Contrib Nephrol
, vol.132
, pp. 354-366
-
-
Pinsky, M.R.1
-
25
-
-
0034812705
-
Mechanisms for modulating TNF alpha in immune and inflammatory disease
-
Baugh JA, Bucala R (2001) Mechanisms for modulating TNF alpha in immune and inflammatory disease. Curr Opin Drug Discov Devel 4(5):635-650
-
(2001)
Curr Opin Drug Discov Devel
, vol.4
, Issue.5
, pp. 635-650
-
-
Baugh, J.A.1
Bucala, R.2
-
26
-
-
0037204948
-
TNF-R1 signaling: A beautiful pathway
-
Chen G, Goeddel DV (2002) TNF-R1 signaling: a beautiful pathway. Science 296(5573):1634-1635
-
(2002)
Science
, vol.296
, Issue.5573
, pp. 1634-1635
-
-
Chen, G.1
Goeddel, D.V.2
-
27
-
-
84864247996
-
Computational and systems biology in trauma and sepsis: Current state and future perspectives
-
An G, Nieman G, Vodovotz Y (2012) Computational and systems biology in trauma and sepsis: current state and future perspectives. Int J Burns Trauma 2:1-10
-
(2012)
Int J Burns Trauma
, vol.2
, pp. 1-10
-
-
An, G.1
Nieman, G.2
Vodovotz, Y.3
-
28
-
-
84868357677
-
Toward computational identification of multiscale tipping points in multiple organ failure
-
An G, Nieman G, Vodovotz Y (2012) Toward computational identification of multiscale tipping points in multiple organ failure. Ann Biomed Eng 40(11):2414-2424
-
(2012)
Ann Biomed Eng
, vol.40
, Issue.11
, pp. 2414-2424
-
-
An, G.1
Nieman, G.2
Vodovotz, Y.3
-
29
-
-
84866465712
-
Linking inflammation and cardiorespiratory variability in sepsis via computational modeling
-
Dick TE, Molkov Y, Nieman G, Hsieh Y, Jacono FJ, Doyle J et al (2012) Linking inflammation and cardiorespiratory variability in sepsis via computational modeling. Front Physiol 3:222
-
(2012)
Front Physiol
, vol.3
, pp. 222
-
-
Dick, T.E.1
Molkov, Y.2
Nieman, G.3
Hsieh, Y.4
Jacono, F.J.5
Doyle, J.6
-
31
-
-
21044443402
-
Search for organising principles: Understanding in systems biology
-
Mesarovic MD, Sreenath SN, Keene JD (2004) Search for organising principles: understanding in systems biology. Syst Biol (Stevenage) 1(1):19-27
-
(2004)
Syst Biol (Stevenage)
, vol.1
, Issue.1
, pp. 19-27
-
-
Mesarovic, M.D.1
Sreenath, S.N.2
Keene, J.D.3
-
32
-
-
33750351769
-
Data-driven modelling of signal-transduction networks
-
Janes KA, Yaffe MB (2006) Data-driven modelling of signal-transduction networks. Nat Rev Mol Cell Biol 7(11):820-828
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, Issue.11
, pp. 820-828
-
-
Janes, K.A.1
Yaffe, M.B.2
-
33
-
-
0036500993
-
Systems biology: A brief overview
-
Kitano H (2002) Systems biology: a brief overview. Science 295(5560):1662-1664
-
(2002)
Science
, vol.295
, Issue.5560
, pp. 1662-1664
-
-
Kitano, H.1
-
34
-
-
79952643760
-
Network news: Innovations in 21st century systems biology
-
Arkin AP, Schaffer DV (2011) Network news: innovations in 21st century systems biology. Cell 144(6):844-849
-
(2011)
Cell
, vol.144
, Issue.6
, pp. 844-849
-
-
Arkin, A.P.1
Schaffer, D.V.2
-
35
-
-
33747094446
-
A reduced mathematical model of the acute inflammatory response II. Capturing scenarios of repeated endotoxin administration
-
Day J, Rubin J, Vodovotz Y, Chow CC, Reynolds A, Clermont G (2006) A reduced mathematical model of the acute inflammatory response II. Capturing scenarios of repeated endotoxin administration. J Theor Biol 242(1):237-256
-
(2006)
J Theor Biol
, vol.242
, Issue.1
, pp. 237-256
-
-
Day, J.1
Rubin, J.2
Vodovotz, Y.3
Chow, C.C.4
Reynolds, A.5
Clermont, G.6
-
36
-
-
33749022785
-
Silico and in vivo approach to elucidate the inflammatory complexity of CD14-deficient mice
-
Prince JM, Levy RM, Bartels J, Baratt A, Kane JM III, Lagoa C et al (2006) In silico and in vivo approach to elucidate the inflammatory complexity of CD14-deficient mice. Mol Med 12(4-6):88-96
-
(2006)
Mol Med
, vol.12
, Issue.4-6
, pp. 88-96
-
-
Prince, J.M.1
Levy, R.M.2
Bartels, J.3
Baratt, A.4
Kane Iii, J.M.5
Lagoa, C.6
-
37
-
-
37549004342
-
A mathematical simulation of the inflammatory response to anthrax infection
-
Kumar R, Chow CC, Bartels JD, Clermont G, Vodovotz Y (2008) A mathematical simulation of the inflammatory response to anthrax infection. Shock 29(1):104-111
-
(2008)
Shock
, vol.29
, Issue.1
, pp. 104-111
-
-
Kumar, R.1
Chow, C.C.2
Bartels, J.D.3
Clermont, G.4
Vodovotz, Y.5
-
38
-
-
84906510400
-
Time varying patterns of organ failure
-
Constantine G, Buliga M, Vodovotz Y, Bohnen N, Clermont G (2010) Time varying patterns of organ failure. Int J Contemp Math Sci 5:2263-2272
-
(2010)
Int J Contemp Math Sci
, vol.5
, pp. 2263-2272
-
-
Constantine, G.1
Buliga, M.2
Vodovotz, Y.3
Bohnen, N.4
Clermont, G.5
-
39
-
-
0034126611
-
Regression and model-building in conservation biology, biogeography and ecology: The distinction between GÇô and reconciliation of GÇô GÇÿpredictiveGÇÖ and GÇÿexplanatoryGÇÖ models
-
Mac Nally R (2000) Regression and model-building in conservation biology, biogeography and ecology: the distinction between GÇô and reconciliation of GÇô GÇÿpredictiveGÇÖ and GÇÿexplanatoryGÇÖ models. Biodivers Conserv 9(5):655-671
-
(2000)
Biodivers Conserv
, vol.9
, Issue.5
, pp. 655-671
-
-
Mac Nally, R.1
-
40
-
-
0034790629
-
Molecular signatures of sepsis: Multiorgan gene expression profiles of systemic inflammation
-
Chinnaiyan AM, Huber-Lang M, Kumar-Sinha C, Barrette TR, Shankar-Sinha S, Sarma VJ et al (2001) Molecular signatures of sepsis: multiorgan gene expression profiles of systemic inflammation. Am J Pathol 159(4):1199-1209
-
(2001)
Am J Pathol
, vol.159
, Issue.4
, pp. 1199-1209
-
-
Chinnaiyan, A.M.1
Huber-Lang, M.2
Kumar-Sinha, C.3
Barrette, T.R.4
Shankar-Sinha, S.5
Sarma, V.J.6
-
41
-
-
2442587841
-
Differential gene expression in gram-negative and gram-positive sepsis
-
Yu SL, Chen HW, Yang PC, Peck K, Tsai MH, Chen JJ et al (2004) Differential gene expression in gram-negative and gram-positive sepsis. Am J Respir Crit Care Med 169(10):1135-1143
-
(2004)
Am J Respir Crit Care Med
, vol.169
, Issue.10
, pp. 1135-1143
-
-
Yu, S.L.1
Chen, H.W.2
Yang, P.C.3
Peck, K.4
Tsai, M.H.5
Chen, J.J.6
-
42
-
-
33645765157
-
Commonality and differences in leukocyte gene expression patterns among three models of inflammation and injury
-
Brownstein BH, Logvinenko T, Lederer JA, Cobb JP, Hubbard WJ, Chaudry IH et al (2006) Commonality and differences in leukocyte gene expression patterns among three models of inflammation and injury. Physiol Genomics 24(3):298-309
-
(2006)
Physiol Genomics
, vol.24
, Issue.3
, pp. 298-309
-
-
Brownstein, B.H.1
Logvinenko, T.2
Lederer, J.A.3
Cobb, J.P.4
Hubbard, W.J.5
Chaudry, I.H.6
-
43
-
-
80054798414
-
Transcriptomic response of murine liver to severe injury and hemorrhagic shock: A dual platform microarray analysis
-
Edmonds RD, Vodovotz Y, Lagoa C, Dutta-Moscato J, Ching Y, Fink MP et al (2011) Transcriptomic response of murine liver to severe injury and hemorrhagic shock: a dual platform microarray analysis. Physiol Genomics 43:1170-1183
-
(2011)
Physiol Genomics
, vol.43
, pp. 1170-1183
-
-
Edmonds, R.D.1
Vodovotz, Y.2
Lagoa, C.3
Dutta-Moscato, J.4
Ching, Y.5
Fink, M.P.6
-
44
-
-
13644261479
-
Expression profiling: Toward an application in sepsis diagnostics
-
Prucha M, Ruryk A, Boriss H, Moller E, Zazula R, Herold I et al (2004) Expression profiling: toward an application in sepsis diagnostics. Shock 22(1):29-33
-
(2004)
Shock
, vol.22
, Issue.1
, pp. 29-33
-
-
Prucha, M.1
Ruryk, A.2
Boriss, H.3
Moller, E.4
Zazula, R.5
Herold, I.6
-
45
-
-
33746345574
-
Systemic transcriptional analysis in survivor and non-survivor septic shock patients: A preliminary study
-
Pachot A, Lepape A, Vey S, Bienvenu J, Mougin B, Monneret G (2006) Systemic transcriptional analysis in survivor and non-survivor septic shock patients: a preliminary study. Immunol Lett 106(1):63-71
-
(2006)
Immunol Lett
, vol.106
, Issue.1
, pp. 63-71
-
-
Pachot, A.1
Lepape, A.2
Vey, S.3
Bienvenu, J.4
Mougin, B.5
Monneret, G.6
-
46
-
-
35348925444
-
Genome-level longitudinal expression of signaling pathways and gene networks in pediatric septic shock
-
Shanley TP, Cvijanovich N, Lin R, Allen GL, Thomas NJ, Doctor A et al (2007) Genome-level longitudinal expression of signaling pathways and gene networks in pediatric septic shock. Mol Med 13(9-10):495-508
-
(2007)
Mol Med
, vol.13
, Issue.9-10
, pp. 495-508
-
-
Shanley, T.P.1
Cvijanovich, N.2
Lin, R.3
Allen, G.L.4
Thomas, N.J.5
Doctor, A.6
-
47
-
-
27144509163
-
A networkbased analysis of systemic inflammation in humans
-
Calvano SE, Xiao W, Richards DR, Felciano RM, Baker HV, Cho RJ et al (2005) A networkbased analysis of systemic inflammation in humans. Nature 437:1032-1037
-
(2005)
Nature
, vol.437
, pp. 1032-1037
-
-
Calvano, S.E.1
Xiao, W.2
Richards, D.R.3
Felciano, R.M.4
Baker, H.V.5
Cho, R.J.6
-
48
-
-
84862908403
-
A genomic storm in critically injured humans
-
Xiao W, Mindrinos MN, Seok J, Cuschieri J, Cuenca AG, Gao H et al (2011) A genomic storm in critically injured humans. J Exp Med 208(13):2581-2590
-
(2011)
J Exp Med
, vol.208
, Issue.13
, pp. 2581-2590
-
-
Xiao, W.1
Mindrinos, M.N.2
Seok, J.3
Cuschieri, J.4
Cuenca, A.G.5
Gao, H.6
-
49
-
-
33646036758
-
The response of human epithelial cells to TNF Involves an inducible autocrine cascade
-
Janes KA, Gaudet S, Albeck JG, Nielsen UB, Lauffenburger DA, Sorger PK (2006) The response of human epithelial cells to TNF Involves an inducible autocrine cascade. Cell 124(6):1225-1239
-
(2006)
Cell
, vol.124
, Issue.6
, pp. 1225-1239
-
-
Janes, K.A.1
Gaudet, S.2
Albeck, J.G.3
Nielsen, U.B.4
Lauffenburger, D.A.5
Sorger, P.K.6
-
50
-
-
84870827578
-
Hemoadsorption reprograms inflammation in experimental gram-negative septic fibrin peritonitis: Insights from in vivo and in silico studies
-
Namas R, Namas R, Lagoa C, Barclay D, Mi Q, Zamora R et al (2012) Hemoadsorption reprograms inflammation in experimental gram-negative septic fibrin peritonitis: insights from in vivo and in silico studies. Mol Med 18:1366-1374
-
(2012)
Mol Med
, vol.18
, pp. 1366-1374
-
-
Namas, R.1
Namas, R.2
Lagoa, C.3
Barclay, D.4
Mi, Q.5
Zamora, R.6
-
51
-
-
77952163906
-
Translational systems approaches to the biology of inflammation and healing
-
Vodovotz Y, Constantine G, Faeder J, Mi Q, Rubin J, Bartels J et al (2010) Translational systems approaches to the biology of inflammation and healing. Immunopharmacol Immunotoxicol 32(2):181-195
-
(2010)
Immunopharmacol Immunotoxicol
, vol.32
, Issue.2
, pp. 181-195
-
-
Vodovotz, Y.1
Constantine, G.2
Faeder, J.3
Mi, Q.4
Rubin, J.5
Bartels, J.6
-
52
-
-
0036965965
-
Inflammatory response in acute traumatic brain injury: A double-edged sword
-
Morganti-Kossmann MC, Rancan M, Stahel PF, Kossmann T (2002) Inflammatory response in acute traumatic brain injury: a double-edged sword. Curr Opin Crit Care 8(2):101-105
-
(2002)
Curr Opin Crit Care
, vol.8
, Issue.2
, pp. 101-105
-
-
Morganti-Kossmann, M.C.1
Rancan, M.2
Stahel, P.F.3
Kossmann, T.4
-
53
-
-
0025185880
-
Cytokine networking in lung inflammation
-
Kunkel SL, Strieter RM (1990) Cytokine networking in lung inflammation. Hosp Pract (Off Ed) 25(10):63-66
-
(1990)
Hosp Pract (Off Ed)
, vol.25
, Issue.10
, pp. 63-66
-
-
Kunkel, S.L.1
Strieter, R.M.2
-
54
-
-
0025289423
-
Cytokine networks in the regulation of inflammation and fibrosis in the lung
-
Elias JA, Freundlich B, Kern JA, Rosenbloom J (1990) Cytokine networks in the regulation of inflammation and fibrosis in the lung. Chest 97(6):1439-1445
-
(1990)
Chest
, vol.97
, Issue.6
, pp. 1439-1445
-
-
Elias, J.A.1
Freundlich, B.2
Kern, J.A.3
Rosenbloom, J.4
-
55
-
-
1942531962
-
An update on the cytokine network in rheumatoid arthritis
-
Miossec P (2004) An update on the cytokine network in rheumatoid arthritis. Curr Opin Rheumatol 16(3):218-222
-
(2004)
Curr Opin Rheumatol
, vol.16
, Issue.3
, pp. 218-222
-
-
Miossec, P.1
-
56
-
-
33947156679
-
The innate immune response to infection, toxins and trauma evolved into networks of interactive, defensive, reparative, regulatory, injurious and pathogenic pathways
-
Stavitsky AB (2007) The innate immune response to infection, toxins and trauma evolved into networks of interactive, defensive, reparative, regulatory, injurious and pathogenic pathways. Mol Immunol 44(11):2787-2799
-
(2007)
Mol Immunol
, vol.44
, Issue.11
, pp. 2787-2799
-
-
Stavitsky, A.B.1
-
57
-
-
84975806501
-
Inflammatory networks in ageing, age-related diseases and longevity
-
Vasto S, Candore G, Balistreri CR, Caruso M, Colonna-Romano G, Grimaldi MP et al (2007) Inflammatory networks in ageing, age-related diseases and longevity. Mech Ageing Dev 128(1):83-91
-
(2007)
Mech Ageing Dev
, vol.128
, Issue.1
, pp. 83-91
-
-
Vasto, S.1
Candore, G.2
Balistreri, C.R.3
Caruso, M.4
Colonna-Romano, G.5
Grimaldi, M.P.6
-
58
-
-
71749089391
-
Networks, biology and systems engineering: A case study in inflammation
-
Foteinou PT, Yang E, Androulakis IP (2009) Networks, biology and systems engineering: a case study in inflammation. Comput Chem Eng 33(12):2028-2041
-
(2009)
Comput Chem Eng
, vol.33
, Issue.12
, pp. 2028-2041
-
-
Foteinou, P.T.1
Yang, E.2
Androulakis, I.P.3
-
59
-
-
77956554551
-
Networks inferred from biochemical data reveal profound differences in toll-like receptor and inflammatory signaling between normal and transformed hepatocytes
-
Alexopoulos LG, Saez-Rodriguez J, Cosgrove BD, Lauffenburger DA, Sorger PK (2010) Networks inferred from biochemical data reveal profound differences in toll-like receptor and inflammatory signaling between normal and transformed hepatocytes. Mol Cell Proteomics 9(9):1849-1865
-
(2010)
Mol Cell Proteomics
, vol.9
, Issue.9
, pp. 1849-1865
-
-
Alexopoulos, L.G.1
Saez-Rodriguez, J.2
Cosgrove, B.D.3
Lauffenburger, D.A.4
Sorger, P.K.5
-
60
-
-
0344464762
-
Sensitivity and specificity of inferring genetic regulatory interactions from microarray experiments with dynamic Bayesian networks
-
Husmeier D (2003) Sensitivity and specificity of inferring genetic regulatory interactions from microarray experiments with dynamic Bayesian networks. Bioinformatics 19(17):2271-2282
-
(2003)
Bioinformatics
, vol.19
, Issue.17
, pp. 2271-2282
-
-
Husmeier, D.1
-
61
-
-
13844276694
-
Cluster analysis for gene expression data: A survey
-
Jiang D, Tang C, Zhang A (2004) Cluster analysis for gene expression data: a survey. IEEE Trans Knowl Data Eng 16(11):1370-1386
-
(2004)
IEEE Trans Knowl Data Eng
, vol.16
, Issue.11
, pp. 1370-1386
-
-
Jiang, D.1
Tang, C.2
Zhang, A.3
-
62
-
-
75149168911
-
Using mechanistic Bayesian networks to identify downstream targets of the sonic hedgehog pathway
-
Shah A, Tenzen T, McMahon AP, Woolf PJ (2009) Using mechanistic Bayesian networks to identify downstream targets of the sonic hedgehog pathway. BMC Bioinformatics 10:433
-
(2009)
BMC Bioinformatics
, vol.10
, pp. 433
-
-
Shah, A.1
Tenzen, T.2
McMahon, A.P.3
Woolf, P.J.4
-
63
-
-
35649010459
-
Steady state approach to model gene regulatory networkssimulation of microarray experiments
-
Rawool SB, Venkatesh KV (2007) Steady state approach to model gene regulatory networkssimulation of microarray experiments. Biosystems 90(3):636-655
-
(2007)
Biosystems
, vol.90
, Issue.3
, pp. 636-655
-
-
Rawool, S.B.1
Venkatesh, K.V.2
-
64
-
-
33947124585
-
Acute liver failure in children
-
Cochran JB, Losek JD (2007) Acute liver failure in children. Pediatr Emerg Care 23(2):129-135
-
(2007)
Pediatr Emerg Care
, vol.23
, Issue.2
, pp. 129-135
-
-
Cochran, J.B.1
Losek, J.D.2
-
65
-
-
84861095555
-
Management and prognosis of acute liver failure in children
-
D'Agostino D, Diaz S, Sanchez MC, Boldrini G (2012) Management and prognosis of acute liver failure in children. Curr Gastroenterol Rep 14(3):262-269
-
(2012)
Curr Gastroenterol Rep
, vol.14
, Issue.3
, pp. 262-269
-
-
D'agostino, D.1
Diaz, S.2
Sanchez, M.C.3
Boldrini, G.4
-
66
-
-
1242274449
-
Detection of multistability, bifurcations, and hysteresis in a large class of biological positive-feedback systems
-
Angeli D, Ferrell JE, Sontag ED (2004) Detection of multistability, bifurcations, and hysteresis in a large class of biological positive-feedback systems. Proc Natl Acad Sci USA 101(7):1822-1827
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, Issue.7
, pp. 1822-1827
-
-
Angeli, D.1
Ferrell, J.E.2
Sontag, E.D.3
-
67
-
-
84916233811
-
Mathematical simulation of the innate immune response
-
Clermont G, Chow CC, Kumar R, Vodovotz Y (2001) Mathematical simulation of the innate immune response. CCM 29(12 Suppl):A111
-
(2001)
CCM
, vol.29
, Issue.12
, pp. A111
-
-
Clermont, G.1
Chow, C.C.2
Kumar, R.3
Vodovotz, Y.4
-
68
-
-
33646124974
-
Bistability in apoptosis: Roles of bax, bcl-2, and mitochondrial permeability transition pores
-
Bagci EZ, Vodovotz Y, Billiar TR, Ermentrout GB, Bahar I (2006) Bistability in apoptosis: roles of bax, bcl-2, and mitochondrial permeability transition pores. Biophys J 90(5):1546-1559
-
(2006)
Biophys J
, vol.90
, Issue.5
, pp. 1546-1559
-
-
Bagci, E.Z.1
Vodovotz, Y.2
Billiar, T.R.3
Ermentrout, G.B.4
Bahar, I.5
-
69
-
-
45449094504
-
A methodology for performing global uncertainty and sensitivity analysis in systems biology
-
Marino S, Hogue IB, Ray CJ, Kirschner DE (2008) A methodology for performing global uncertainty and sensitivity analysis in systems biology. J Theor Biol 254(1):178-196
-
(2008)
J Theor Biol
, vol.254
, Issue.1
, pp. 178-196
-
-
Marino, S.1
Hogue, I.B.2
Ray, C.J.3
Kirschner, D.E.4
-
70
-
-
0036500834
-
Reverse engineering of biological complexity
-
Csete ME, Doyle JC (2002) Reverse engineering of biological complexity. Science 295(5560):1664-1669
-
(2002)
Science
, vol.295
, Issue.5560
, pp. 1664-1669
-
-
Csete, M.E.1
Doyle, J.C.2
-
71
-
-
33746639260
-
Modulebased analysis of robustness tradeoffs in the heat shock response system
-
Kurata H, El-Samad H, Iwasaki R, Ohtake H, Doyle JC, Grigorova I et al (2006) Modulebased analysis of robustness tradeoffs in the heat shock response system. PLoS Comput Biol 2(7):e59
-
(2006)
PLoS Comput Biol
, vol.2
, Issue.7
, pp. e59
-
-
Kurata, H.1
El-Samad, H.2
Iwasaki, R.3
Ohtake, H.4
Doyle, J.C.5
Grigorova, I.6
-
72
-
-
34249826054
-
Challenges and rewards on the road to translational systems biology in acute illness: Four case reports from interdisciplinary teams
-
An G, Hunt CA, Clermont G, Neugebauer E, Vodovotz Y (2007) Challenges and rewards on the road to translational systems biology in acute illness: four case reports from interdisciplinary teams. J Crit Care 22:169-175
-
(2007)
J Crit Care
, vol.22
, pp. 169-175
-
-
An, G.1
Hunt, C.A.2
Clermont, G.3
Neugebauer, E.4
Vodovotz, Y.5
-
73
-
-
41849114552
-
Translational systems biology: Introduction of an engineering approach to the pathophysiology of the burn patient
-
An G, Faeder J, Vodovotz Y (2008) Translational systems biology: introduction of an engineering approach to the pathophysiology of the burn patient. J Burn Care Res 29:277-285
-
(2008)
J Burn Care Res
, vol.29
, pp. 277-285
-
-
An, G.1
Faeder, J.2
Vodovotz, Y.3
-
74
-
-
4744344132
-
Silico experiments of existing and hypothetical cytokine-directed clinical trials using agent based modeling
-
An G (2004) In-silico experiments of existing and hypothetical cytokine-directed clinical trials using agent based modeling. Crit Care Med 32:2050-2060
-
(2004)
Crit Care Med
, vol.32
, pp. 2050-2060
-
-
An, G.1
-
76
-
-
4043056616
-
Silico design of clinical trials: A method coming of age
-
Clermont G, Bartels J, Kumar R, Constantine G, Vodovotz Y, Chow C (2004) In silico design of clinical trials: a method coming of age. Crit Care Med 32:2061-2070
-
(2004)
Crit Care Med
, vol.32
, pp. 2061-2070
-
-
Clermont, G.1
Bartels, J.2
Kumar, R.3
Constantine, G.4
Vodovotz, Y.5
Chow, C.6
-
77
-
-
47849114337
-
An ensemble of models of the acute inflammatory response to bacterial lipopolysaccharide in rats: Results from parameter space reduction
-
Daun S, Rubin J, Vodovotz Y, Roy A, Parker R, Clermont G (2008) An ensemble of models of the acute inflammatory response to bacterial lipopolysaccharide in rats: results from parameter space reduction. J Theor Biol 253:843-853
-
(2008)
J Theor Biol
, vol.253
, pp. 843-853
-
-
Daun, S.1
Rubin, J.2
Vodovotz, Y.3
Roy, A.4
Parker, R.5
Clermont, G.6
-
78
-
-
57849104348
-
Modeling endotoxin-induced systemic inflammation using an indirect response approach
-
Foteinou PT, Calvano SE, Lowry SF, Androulakis IP (2009) Modeling endotoxin-induced systemic inflammation using an indirect response approach. Math Biosci 217:27-42
-
(2009)
Math Biosci
, vol.217
, pp. 27-42
-
-
Foteinou, P.T.1
Calvano, S.E.2
Lowry, S.F.3
Androulakis, I.P.4
-
79
-
-
62849112761
-
Silico simulation of corticosteroids effect on an NFkB- dependent physicochemical model of systemic inflammation
-
Foteinou PT, Calvano SE, Lowry SF, Androulakis IP (2009) In silico simulation of corticosteroids effect on an NFkB- dependent physicochemical model of systemic inflammation. PLoS One 4(3):e4706
-
(2009)
PLoS One
, vol.4
, Issue.3
, pp. e4706
-
-
Foteinou, P.T.1
Calvano, S.E.2
Lowry, S.F.3
Androulakis, I.P.4
-
80
-
-
57849158644
-
Detailed qualitative dynamic knowledge representation using a BioNetGen model of TLR-4 signaling and preconditioning
-
An G, Faeder JR (2009) Detailed qualitative dynamic knowledge representation using a BioNetGen model of TLR-4 signaling and preconditioning. Math Biosci 217:53-63
-
(2009)
Math Biosci
, vol.217
, pp. 53-63
-
-
An, G.1
Faeder, J.R.2
-
81
-
-
57849103868
-
A model of TLR4 signaling and tolerance using a qualitative, particle event-based method: Introduction of spatially configured stochastic reaction chambers (SCSRC)
-
An G (2009) A model of TLR4 signaling and tolerance using a qualitative, particle event-based method: introduction of spatially configured stochastic reaction chambers (SCSRC). Math Biosci 217:43-52
-
(2009)
Math Biosci
, vol.217
, pp. 43-52
-
-
An, G.1
-
82
-
-
57749186048
-
A simple mathematical model of signaling resulting from the binding of lipopolysaccharide with Toll-like receptor 4 demonstrates inherent preconditioning behavior
-
Rivière B, Epshteyn Y, Swigon D, Vodovotz Y (2009) A simple mathematical model of signaling resulting from the binding of lipopolysaccharide with Toll-like receptor 4 demonstrates inherent preconditioning behavior. Math Biosci 217:19-26
-
(2009)
Math Biosci
, vol.217
, pp. 19-26
-
-
Rivière, B.1
Epshteyn, Y.2
Swigon, D.3
Vodovotz, Y.4
-
83
-
-
84863338100
-
A two-compartment mathematical model of endotoxin-induced inflammatory and physiologic alterations in swine
-
Nieman K, Brown D, Sarkar J, Kubiak B, Ziraldo C, Vieau C et al (2012) A two-compartment mathematical model of endotoxin-induced inflammatory and physiologic alterations in swine. Crit Care Med 40:1052-1063
-
(2012)
Crit Care Med
, vol.40
, pp. 1052-1063
-
-
Nieman, K.1
Brown, D.2
Sarkar, J.3
Kubiak, B.4
Ziraldo, C.5
Vieau, C.6
-
84
-
-
77949496645
-
Agent-based modeling of endotoxin-induced acute inflammatory response in human blood leukocytes
-
Dong X, Foteinou PT, Calvano SE, Lowry SF, Androulakis IP (2010) Agent-based modeling of endotoxin-induced acute inflammatory response in human blood leukocytes. PLoS One 5(2):e9249
-
(2010)
PLoS One
, vol.5
, Issue.2
, pp. e9249
-
-
Dong, X.1
Foteinou, P.T.2
Calvano, S.E.3
Lowry, S.F.4
Androulakis, I.P.5
-
85
-
-
77953214777
-
Multiscale model for the assessment of autonomic dysfunction in human endotoxemia
-
Foteinou PT, Calvano SE, Lowry SF, Androulakis IP (2010) Multiscale model for the assessment of autonomic dysfunction in human endotoxemia. Physiol Genomics 42(1):5-19
-
(2010)
Physiol Genomics
, vol.42
, Issue.1
, pp. 5-19
-
-
Foteinou, P.T.1
Calvano, S.E.2
Lowry, S.F.3
Androulakis, I.P.4
-
86
-
-
77952597821
-
Modeling the influence of circadian rhythms on the acute inflammatory response
-
Scheff JD, Calvano SE, Lowry SF, Androulakis IP (2010) Modeling the influence of circadian rhythms on the acute inflammatory response. J Theor Biol 264(3):1068-1076
-
(2010)
J Theor Biol
, vol.264
, Issue.3
, pp. 1068-1076
-
-
Scheff, J.D.1
Calvano, S.E.2
Lowry, S.F.3
Androulakis, I.P.4
-
87
-
-
79952163506
-
A physiological model for autonomic heart rate regulation in human endotoxemia
-
Foteinou PT, Calvano SE, Lowry SF, Androulakis IP (2011) A physiological model for autonomic heart rate regulation in human endotoxemia. Shock 35(3):229-239
-
(2011)
Shock
, vol.35
, Issue.3
, pp. 229-239
-
-
Foteinou, P.T.1
Calvano, S.E.2
Lowry, S.F.3
Androulakis, I.P.4
-
88
-
-
79960132229
-
A dual negative regulation model of toll-like receptor 4 signaling for endotoxin preconditioning in human endotoxemia
-
Yang Q, Calvano SE, Lowry SF, Androulakis IP (2011) A dual negative regulation model of toll-like receptor 4 signaling for endotoxin preconditioning in human endotoxemia. Math Biosci 232(2):151-163
-
(2011)
Math Biosci
, vol.232
, Issue.2
, pp. 151-163
-
-
Yang, Q.1
Calvano, S.E.2
Lowry, S.F.3
Androulakis, I.P.4
-
89
-
-
77956321525
-
Using a mathematical model to analyze the role of probiotics and inflammation in necrotizing enterocolitis
-
Arciero J, Rubin J, Upperman J, Vodovotz Y, Ermentrout GB (2010) Using a mathematical model to analyze the role of probiotics and inflammation in necrotizing enterocolitis. PLoS One 5:e10066
-
(2010)
PLoS One
, vol.5
, pp. e10066
-
-
Arciero, J.1
Rubin, J.2
Upperman, J.3
Vodovotz, Y.4
Ermentrout, G.B.5
-
90
-
-
84863272764
-
Immature oxidative stress management as a unifying principle in the pathogenesis of necrotizing enterocolitis: Insights from an agentbased model
-
Kim M, Christley S, Alverdy JC, Liu D, An G (2012) Immature oxidative stress management as a unifying principle in the pathogenesis of necrotizing enterocolitis: insights from an agentbased model. Surg Infect (Larchmt) 13(1):18-32
-
(2012)
Surg Infect (Larchmt)
, vol.13
, Issue.1
, pp. 18-32
-
-
Kim, M.1
Christley, S.2
Alverdy, J.C.3
Liu, D.4
An, G.5
-
91
-
-
79957543031
-
Compartmentation of NAD+-dependent signalling
-
Koch-Nolte F, Fischer S, Haag F, Ziegler M (2011) Compartmentation of NAD+-dependent signalling. FEBS Lett 585(11):1651-1656
-
(2011)
FEBS Lett
, vol.585
, Issue.11
, pp. 1651-1656
-
-
Koch-Nolte, F.1
Fischer, S.2
Haag, F.3
Ziegler, M.4
-
92
-
-
84866121024
-
Identification of a novel pathway of TGF-beta1 regulation by extracellular NAD+ in mouse macrophages: In vitro and in silico studies
-
Zamora R, Azhar N, Namas R, Metukuri MR, Clermont T, Gladstone C et al (2012) Identification of a novel pathway of TGF-beta1 regulation by extracellular NAD+ in mouse macrophages: in vitro and in silico studies. J Biol Chem 287:31003-31014
-
(2012)
J Biol Chem
, vol.287
, pp. 31003-31014
-
-
Zamora, R.1
Azhar, N.2
Namas, R.3
Metukuri, M.R.4
Clermont, T.5
Gladstone, C.6
|