A simple mathematical model of signaling resulting from the binding of lipopolysaccharide with Toll-like receptor 4 demonstrates inherent preconditioning behavior

Mathematical Biosciences

Volumn 217, Issue 1, 2009, Pages 19-26

  Rivière, Beatrice ^a   Epshteyn, Yekaterina ^a   Swigon, David ^a   Vodovotz, Yoram ^a,b  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

Author keywords

Endotoxin; Inflammation; Mathematical model; Preconditioning; Sepsis; Tolerance

Indexed keywords

FUNCTIONS; LINEAR SYSTEMS; NONLINEAR SYSTEMS; ORDINARY DIFFERENTIAL EQUATIONS; PATHOLOGY; POLYSACCHARIDES; TIME MEASUREMENT;

ENDOTOXIN; INFLAMMATION; PRECONDITIONING; SEPSIS; TOLERANCE;

MATHEMATICAL MODELS;

LIPOPOLYSACCHARIDE; TOLL LIKE RECEPTOR 4;

BACTERIAL DISEASE; BACTERIUM; IMMUNE RESPONSE; NUMERICAL MODEL; POLYSACCHARIDE; TOLERANCE; TOXIN;

ANTIGEN EXPRESSION; ARTICLE; BINDING AFFINITY; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; MATHEMATICAL ANALYSIS; MATHEMATICAL COMPUTING; MATHEMATICAL MODEL; NONLINEAR SYSTEM; SEPSIS; SIGNAL TRANSDUCTION;

COMPUTER SIMULATION; INFLAMMATION; LIPOPOLYSACCHARIDES; MODELS, BIOLOGICAL; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4;

BACTERIA (MICROORGANISMS); NEGIBACTERIA;

EID: 57749186048     PISSN: 00255564     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mbs.2008.10.002     Document Type: Article

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