Agent-based modeling of endotoxin-induced acute inflammatory response in human blood leukocytes

PLoS ONE

Volumn 5, Issue 2, 2010, Pages

  Dong, Xu ^a   Foteinou, Panagiota T ^a   Calvano, Steven E ^b   Lowry, Stephen F ^b   Androulakis, Ioannis P ^a  

^a RUTGERS UNIVERSITY   (United States)

^b ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTOXIN; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 12; INTERLEUKIN 4; LIPOPOLYSACCHARIDE; RNA; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR;

AGENT BASED MODELING; ARTICLE; CELL COMMUNICATION; CELL FUNCTION; CELL HETEROGENEITY; COMPUTER MODEL; COMPUTER PROGRAM; CONCEPTUAL FRAMEWORK; CONTROLLED STUDY; CYTOLYSIS; ERYTHROCYTE; HELPER CELL; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOLOGICAL TOLERANCE; INFLAMMATION; INTRACELLULAR SPACE; LEUKOCYTE; MACROPHAGE; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MOLECULE; NONLINEAR SYSTEM; RNA ISOLATION; SIMULATION; SPATIAL ORIENTATION; THEORETICAL MODEL; ACUTE DISEASE; BIOLOGICAL MODEL; BLOOD; CHEMICALLY INDUCED DISORDER; DRUG EFFECT; GENE EXPRESSION PROFILING; GENETIC TRANSCRIPTION; IMMUNE SYSTEM; IMMUNOLOGY; METABOLISM; PROTEIN BINDING; SIGNAL TRANSDUCTION; TH1 CELL; TH2 CELL;

ACUTE DISEASE; ENDOTOXINS; GENE EXPRESSION PROFILING; HUMANS; IMMUNE SYSTEM; INFLAMMATION; LEUKOCYTES; LIPOPOLYSACCHARIDES; MACROPHAGES; MODELS, IMMUNOLOGICAL; NF-KAPPA B; PROTEIN BINDING; SIGNAL TRANSDUCTION; SOFTWARE; TH1 CELLS; TH2 CELLS; TOLL-LIKE RECEPTOR 4; TRANSCRIPTION, GENETIC;

EID: 77949496645     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0009249     Document Type: Article

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