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Volumn 11, Issue 4, 2015, Pages

A Temporal Gate for Viral Enhancers to Co-opt Toll-Like-Receptor Transcriptional Activation Pathways upon Acute Infection

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 9; TOLL LIKE RECEPTOR AGONIST; SMALL INTERFERING RNA; VIRAL PROTEIN;

EID: 84929501320     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1004737     Document Type: Article
Times cited : (5)

References (140)
  • 3
    • 77950343791 scopus 로고    scopus 로고
    • Pattern recognition receptors and inflammation
    • Takeuchi O, Akira S, (2010) Pattern recognition receptors and inflammation. Cell 140: 805–820. doi: 10.1016/j.cell.2010.01.022 20303872
    • (2010) Cell , vol.140 , pp. 805-820
    • Takeuchi, O.1    Akira, S.2
  • 5
    • 31344461659 scopus 로고    scopus 로고
    • Innate immune recognition of viral infection
    • Kawai T, Akira S, (2006) Innate immune recognition of viral infection. Nat Immunol 7: 131–137. 16424890
    • (2006) Nat Immunol , vol.7 , pp. 131-137
    • Kawai, T.1    Akira, S.2
  • 6
    • 0042679529 scopus 로고    scopus 로고
    • Identification of Lps2 as a key transducer of MyD88-independent TIR signalling
    • Hoebe K, Du X, Georgel P, Janssen E, Tabeta K, et al. (2003) Identification of Lps2 as a key transducer of MyD88-independent TIR signalling. Nature 424: 743–748. 12872135
    • (2003) Nature , vol.424 , pp. 743-748
    • Hoebe, K.1    Du, X.2    Georgel, P.3    Janssen, E.4    Tabeta, K.5
  • 7
    • 33748475531 scopus 로고    scopus 로고
    • Type I interferon [corrected] gene induction by the interferon regulatory factor family of transcription factors
    • Honda K, Takaoka A, Taniguchi T, (2006) Type I interferon [corrected] gene induction by the interferon regulatory factor family of transcription factors. Immunity 25: 349–360. 16979567
    • (2006) Immunity , vol.25 , pp. 349-360
    • Honda, K.1    Takaoka, A.2    Taniguchi, T.3
  • 8
    • 33646377870 scopus 로고    scopus 로고
    • Interferon signalling network in innate defence
    • Takaoka A, Yanai H, (2006) Interferon signalling network in innate defence. Cell Microbiol 8: 907–922. 16681834
    • (2006) Cell Microbiol , vol.8 , pp. 907-922
    • Takaoka, A.1    Yanai, H.2
  • 9
    • 0033561760 scopus 로고    scopus 로고
    • Human cytomegalovirus binding to human monocytes induces immunoregulatory gene expression
    • Yurochko AD, Huang ES, (1999) Human cytomegalovirus binding to human monocytes induces immunoregulatory gene expression. J Immunol 162: 4806–4816. 10202024
    • (1999) J Immunol , vol.162 , pp. 4806-4816
    • Yurochko, A.D.1    Huang, E.S.2
  • 10
    • 35748937030 scopus 로고    scopus 로고
    • Recognition of viruses by innate immunity
    • Takeuchi O, Akira S, (2007) Recognition of viruses by innate immunity. Immunol Rev 220: 214–224. 17979849
    • (2007) Immunol Rev , vol.220 , pp. 214-224
    • Takeuchi, O.1    Akira, S.2
  • 11
    • 70350441863 scopus 로고    scopus 로고
    • Toll-like receptor 2 on inflammatory monocytes induces type I interferon in response to viral but not bacterial ligands
    • Barbalat R, Lau L, Locksley RM, Barton GM, (2009) Toll-like receptor 2 on inflammatory monocytes induces type I interferon in response to viral but not bacterial ligands. Nat Immunol 10: 1200–1207. doi: 10.1038/ni.1792 19801985
    • (2009) Nat Immunol , vol.10 , pp. 1200-1207
    • Barbalat, R.1    Lau, L.2    Locksley, R.M.3    Barton, G.M.4
  • 12
    • 0345505220 scopus 로고    scopus 로고
    • Human cytomegalovirus activates inflammatory cytokine responses via CD14 and Toll-like receptor 2
    • Compton T, Kurt-Jones EA, Boehme KW, Belko J, Latz E, et al. (2003) Human cytomegalovirus activates inflammatory cytokine responses via CD14 and Toll-like receptor 2. J Virol 77: 4588–4596. 12663765
    • (2003) J Virol , vol.77 , pp. 4588-4596
    • Compton, T.1    Kurt-Jones, E.A.2    Boehme, K.W.3    Belko, J.4    Latz, E.5
  • 13
    • 33750827767 scopus 로고    scopus 로고
    • Human cytomegalovirus envelope glycoproteins B and H are necessary for TLR2 activation in permissive cells
    • Boehme KW, Guerrero M, Compton T, (2006) Human cytomegalovirus envelope glycoproteins B and H are necessary for TLR2 activation in permissive cells. J Immunol 177: 7094–7102. 17082626
    • (2006) J Immunol , vol.177 , pp. 7094-7102
    • Boehme, K.W.1    Guerrero, M.2    Compton, T.3
  • 14
    • 84864010826 scopus 로고    scopus 로고
    • Herpes Simplex Virus Glycoproteins gH/gL and gB Bind Toll-Like Receptor 2, and Soluble gH/gL Is Sufficient To Activate NFκB
    • Leoni V, Gianni T, Salvioli S, Campadelli-Fiume G, (2012) Herpes Simplex Virus Glycoproteins gH/gL and gB Bind Toll-Like Receptor 2, and Soluble gH/gL Is Sufficient To Activate NFκB. J Virol 86: 6555–6562. doi: 10.1128/JVI.00295-12 22496225
    • (2012) J Virol , vol.86 , pp. 6555-6562
    • Leoni, V.1    Gianni, T.2    Salvioli, S.3    Campadelli-Fiume, G.4
  • 15
    • 12144286763 scopus 로고    scopus 로고
    • Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection
    • Tabeta K, Georgel P, Janssen E, Du X, Hoebe K, et al. (2004) Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection. Proc Natl Acad Sci USA 101: 3516–3521. 14993594
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 3516-3521
    • Tabeta, K.1    Georgel, P.2    Janssen, E.3    Du, X.4    Hoebe, K.5
  • 16
    • 33646200348 scopus 로고    scopus 로고
    • Role for TLR2 in NK cell-mediated control of murine cytomegalovirus in vivo
    • Szomolanyi-Tsuda E, Liang X, Welsh RM, Kurt-Jones EA, Finberg RW, (2006) Role for TLR2 in NK cell-mediated control of murine cytomegalovirus in vivo. J Virol 80: 4286–4291. 16611887
    • (2006) J Virol , vol.80 , pp. 4286-4291
    • Szomolanyi-Tsuda, E.1    Liang, X.2    Welsh, R.M.3    Kurt-Jones, E.A.4    Finberg, R.W.5
  • 17
    • 72849146138 scopus 로고    scopus 로고
    • Human cytomegalovirus induces the interferon response via the DNA sensor ZBP1
    • DeFilippis VR, Alvarado D, Sali T, Rothenburg S, Fruh K, (2010) Human cytomegalovirus induces the interferon response via the DNA sensor ZBP1. J Virol 84: 585–598. doi: 10.1128/JVI.01748-09 19846511
    • (2010) J Virol , vol.84 , pp. 585-598
    • DeFilippis, V.R.1    Alvarado, D.2    Sali, T.3    Rothenburg, S.4    Fruh, K.5
  • 18
    • 77951269392 scopus 로고    scopus 로고
    • The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses
    • Rathinam VA, Jiang Z, Waggoner SN, Sharma S, Cole LE, et al. (2010) The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses. Nat Immunol 11: 395–402. doi: 10.1038/ni.1864 20351692
    • (2010) Nat Immunol , vol.11 , pp. 395-402
    • Rathinam, V.A.1    Jiang, Z.2    Waggoner, S.N.3    Sharma, S.4    Cole, L.E.5
  • 19
    • 0034733741 scopus 로고    scopus 로고
    • A Subset of Viral Transcripts Packaged Within Human Cytomegalovirus Particles
    • Bresnahan WA, Shenk T, (2000) A Subset of Viral Transcripts Packaged Within Human Cytomegalovirus Particles. Science. pp. 2373–2376. 10875924
    • (2000) Science , pp. 2373-2376
    • Bresnahan, W.A.1    Shenk, T.2
  • 20
    • 78049450970 scopus 로고    scopus 로고
    • Innate immune response and viral interference strategies developed by human herpesviruses
    • Vandevenne P, Sadzot-Delvaux C, Piette J, (2010) Innate immune response and viral interference strategies developed by human herpesviruses. Biochem Pharmacol 80: 1955–1972. doi: 10.1016/j.bcp.2010.07.001 20620129
    • (2010) Biochem Pharmacol , vol.80 , pp. 1955-1972
    • Vandevenne, P.1    Sadzot-Delvaux, C.2    Piette, J.3
  • 21
    • 80755172251 scopus 로고    scopus 로고
    • All is fair in virus-host interactions: NK cells and cytomegalovirus
    • Babic M, Krmpotic A, Jonjic S, (2011) All is fair in virus-host interactions: NK cells and cytomegalovirus. Trends Mol Med 17: 677–685. doi: 10.1016/j.molmed.2011.07.003 21852192
    • (2011) Trends Mol Med , vol.17 , pp. 677-685
    • Babic, M.1    Krmpotic, A.2    Jonjic, S.3
  • 22
    • 79955017145 scopus 로고    scopus 로고
    • Human cytomegalovirus immunity and immune evasion
    • Jackson SE, Mason GM, Wills MR, (2011) Human cytomegalovirus immunity and immune evasion. Virus Res 157: 151–160. doi: 10.1016/j.virusres.2010.10.031 21056604
    • (2011) Virus Res , vol.157 , pp. 151-160
    • Jackson, S.E.1    Mason, G.M.2    Wills, M.R.3
  • 23
    • 84867888513 scopus 로고    scopus 로고
    • Murine cytomegalovirus immune evasion proteins operative in the MHC class I pathway of antigen processing and presentation: state of knowledge, revisions, and questions
    • Lemmermann NA, Fink A, Podlech J, Ebert S, Wilhelmi V, et al. (2012) Murine cytomegalovirus immune evasion proteins operative in the MHC class I pathway of antigen processing and presentation: state of knowledge, revisions, and questions. Med Microbiol Immunol 201: 497–512. doi: 10.1007/s00430-012-0257-y 22961127
    • (2012) Med Microbiol Immunol , vol.201 , pp. 497-512
    • Lemmermann, N.A.1    Fink, A.2    Podlech, J.3    Ebert, S.4    Wilhelmi, V.5
  • 24
    • 0141705395 scopus 로고    scopus 로고
    • Human cytomegalovirus UL83-coded pp65 virion protein inhibits antiviral gene expression in infected cells
    • Browne EP, Shenk T, (2003) Human cytomegalovirus UL83-coded pp65 virion protein inhibits antiviral gene expression in infected cells. Proc Natl Acad Sci U S A 100: 11439–11444. 12972646
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 11439-11444
    • Browne, E.P.1    Shenk, T.2
  • 25
    • 4644316070 scopus 로고    scopus 로고
    • Major Human Cytomegalovirus Structural Protein pp65 (ppUL83) Prevents Interferon Response Factor 3 Activation in the Interferon Response
    • Abate DA, Watanabe S, Mocarski ES, (2004) Major Human Cytomegalovirus Structural Protein pp65 (ppUL83) Prevents Interferon Response Factor 3 Activation in the Interferon Response. J Virol 78: 10995–11006. 15452220
    • (2004) J Virol , vol.78 , pp. 10995-11006
    • Abate, D.A.1    Watanabe, S.2    Mocarski, E.S.3
  • 26
    • 14744268143 scopus 로고    scopus 로고
    • Human cytomegalovirus immediate-early 2 gene expression blocks virus-induced beta interferon production
    • Taylor RT, Bresnahan WA, (2005) Human cytomegalovirus immediate-early 2 gene expression blocks virus-induced beta interferon production. J Virol 79: 3873–3877. 15731283
    • (2005) J Virol , vol.79 , pp. 3873-3877
    • Taylor, R.T.1    Bresnahan, W.A.2
  • 27
    • 30344457027 scopus 로고    scopus 로고
    • Human cytomegalovirus immediate-early 2 protein IE86 blocks virus-induced chemokine expression
    • Taylor RT, Bresnahan WA, (2006) Human cytomegalovirus immediate-early 2 protein IE86 blocks virus-induced chemokine expression. J Virol 80: 920–928. 16378994
    • (2006) J Virol , vol.80 , pp. 920-928
    • Taylor, R.T.1    Bresnahan, W.A.2
  • 28
    • 0033563134 scopus 로고    scopus 로고
    • Human Cytomegalovirus Inhibits IFN-α-Stimulated Antiviral and Immunoregulatory Responses by Blocking Multiple Levels of IFN-α Signal Transduction
    • Miller DM, Zhang Y, Rahill BM, Waldman WJ, Sedmak DD, (1999) Human Cytomegalovirus Inhibits IFN-α-Stimulated Antiviral and Immunoregulatory Responses by Blocking Multiple Levels of IFN-α Signal Transduction. J Immunol 162: 6107–6113. 10229853
    • (1999) J Immunol , vol.162 , pp. 6107-6113
    • Miller, D.M.1    Zhang, Y.2    Rahill, B.M.3    Waldman, W.J.4    Sedmak, D.D.5
  • 29
    • 84911463359 scopus 로고    scopus 로고
    • The Human Cytomegalovirus UL26 Protein Antagonizes NF-kappaB Activation
    • Mathers C, Schafer X, Martinez-Sobrido L, Munger J, (2014) The Human Cytomegalovirus UL26 Protein Antagonizes NF-kappaB Activation. J Virol 88: 14289–14300. doi: 10.1128/JVI.02552-14 25275128
    • (2014) J Virol , vol.88 , pp. 14289-14300
    • Mathers, C.1    Schafer, X.2    Martinez-Sobrido, L.3    Munger, J.4
  • 30
    • 54449100076 scopus 로고    scopus 로고
    • Human cytomegalovirus interferes with signal transducer and activator of transcription (STAT) 2 protein stability and tyrosine phosphorylation
    • Le VT, Trilling M, Wilborn M, Hengel H, Zimmermann A, (2008) Human cytomegalovirus interferes with signal transducer and activator of transcription (STAT) 2 protein stability and tyrosine phosphorylation. J Gen Virol 89: 2416–2426. doi: 10.1099/vir.0.2008/001669-0 18796709
    • (2008) J Gen Virol , vol.89 , pp. 2416-2426
    • Le, V.T.1    Trilling, M.2    Wilborn, M.3    Hengel, H.4    Zimmermann, A.5
  • 31
    • 44649160257 scopus 로고    scopus 로고
    • Mouse cytomegalovirus inhibits beta interferon (IFN-beta) gene expression and controls activation pathways of the IFN-beta enhanceosome
    • Le VT, Trilling M, Zimmermann A, Hengel H, (2008) Mouse cytomegalovirus inhibits beta interferon (IFN-beta) gene expression and controls activation pathways of the IFN-beta enhanceosome. J Gen Virol 89: 1131–1141. doi: 10.1099/vir.0.83538-0 18420790
    • (2008) J Gen Virol , vol.89 , pp. 1131-1141
    • Le, V.T.1    Trilling, M.2    Zimmermann, A.3    Hengel, H.4
  • 32
    • 19344375679 scopus 로고    scopus 로고
    • A cytomegaloviral protein reveals a dual role for STAT2 in IFN-γ signaling and antiviral responses
    • Zimmermann A, Trilling M, Wagner M, Wilborn M, Bubic I, et al. (2005) A cytomegaloviral protein reveals a dual role for STAT2 in IFN-γ signaling and antiviral responses. J Ex Med 201: 1543–1553. 15883169
    • (2005) J Ex Med , vol.201 , pp. 1543-1553
    • Zimmermann, A.1    Trilling, M.2    Wagner, M.3    Wilborn, M.4    Bubic, I.5
  • 33
    • 84911443659 scopus 로고    scopus 로고
    • M27 expressed by cytomegalovirus counteracts effective type I interferon induction of myeloid cells but not of plasmacytoid dendritic cells
    • Doring M, Lessin I, Frenz T, Spanier J, Kessler A, et al. (2014) M27 expressed by cytomegalovirus counteracts effective type I interferon induction of myeloid cells but not of plasmacytoid dendritic cells. J Virol 88: 13638–13650. doi: 10.1128/JVI.00216-14 25231302
    • (2014) J Virol , vol.88 , pp. 13638-13650
    • Doring, M.1    Lessin, I.2    Frenz, T.3    Spanier, J.4    Kessler, A.5
  • 34
    • 84860901212 scopus 로고    scopus 로고
    • Viral mediated redirection of NEMO/IKKgamma to autophagosomes curtails the inflammatory cascade
    • Fliss PM, Jowers TP, Brinkmann MM, Holstermann B, Mack C, et al. (2012) Viral mediated redirection of NEMO/IKKgamma to autophagosomes curtails the inflammatory cascade. PLoS Pathog 8: e1002517. doi: 10.1371/journal.ppat.1002517 22319449
    • (2012) PLoS Pathog , vol.8
    • Fliss, P.M.1    Jowers, T.P.2    Brinkmann, M.M.3    Holstermann, B.4    Mack, C.5
  • 35
    • 42949111649 scopus 로고    scopus 로고
    • Inhibition of proinflammatory and innate immune signaling pathways by a cytomegalovirus RIP1-interacting protein
    • Mack C, Sickmann A, Lembo D, Brune W, (2008) Inhibition of proinflammatory and innate immune signaling pathways by a cytomegalovirus RIP1-interacting protein. Proc Natl Acad Sci U S A 105: 3094–3099. doi: 10.1073/pnas.0800168105 18287053
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 3094-3099
    • Mack, C.1    Sickmann, A.2    Lembo, D.3    Brune, W.4
  • 36
    • 84921948609 scopus 로고    scopus 로고
    • Murine cytomegalovirus virion-associated protein M45 mediates rapid NF-kappaB activation after infection
    • Krause E, de Graaf M, Fliss PM, Dolken L, Brune W, (2014) Murine cytomegalovirus virion-associated protein M45 mediates rapid NF-kappaB activation after infection. J Virol 88: 9963–9975. doi: 10.1128/JVI.00684-14 24942588
    • (2014) J Virol , vol.88 , pp. 9963-9975
    • Krause, E.1    de Graaf, M.2    Fliss, P.M.3    Dolken, L.4    Brune, W.5
  • 37
    • 4644312884 scopus 로고    scopus 로고
    • Identification of proteins in human cytomegalovirus (HCMV) particles: the HCMV proteome
    • Varnum SM, Streblow DN, Monroe ME, Smith P, Auberry KJ, et al. (2004) Identification of proteins in human cytomegalovirus (HCMV) particles: the HCMV proteome. J Virol 78: 10960–10966. 15452216
    • (2004) J Virol , vol.78 , pp. 10960-10966
    • Varnum, S.M.1    Streblow, D.N.2    Monroe, M.E.3    Smith, P.4    Auberry, K.J.5
  • 38
    • 0031690756 scopus 로고    scopus 로고
    • Enhancer requirement for murine cytomegalovirus growth and genetic complementation by the human cytomegalovirus enhancer
    • Angulo A, Messerle M, Koszinowski UH, Ghazal P, (1998) Enhancer requirement for murine cytomegalovirus growth and genetic complementation by the human cytomegalovirus enhancer. J Virol 72: 8502–8509. 9765387
    • (1998) J Virol , vol.72 , pp. 8502-8509
    • Angulo, A.1    Messerle, M.2    Koszinowski, U.H.3    Ghazal, P.4
  • 39
    • 0037369093 scopus 로고    scopus 로고
    • An essential role of the enhancer for murine cytomegalovirus in vivo growth and pathogenesis
    • Ghazal P, Messerle M, Osborn K, Angulo A, (2003) An essential role of the enhancer for murine cytomegalovirus in vivo growth and pathogenesis. J Virol 77: 3217–3228. 12584345
    • (2003) J Virol , vol.77 , pp. 3217-3228
    • Ghazal, P.1    Messerle, M.2    Osborn, K.3    Angulo, A.4
  • 41
    • 42249110559 scopus 로고    scopus 로고
    • Role of the cytomegalovirus major immediate early enhancer in acute infection and reactivation from latency
    • Stinski MF, Isomura H, (2008) Role of the cytomegalovirus major immediate early enhancer in acute infection and reactivation from latency. Med Microbiol Immunol 197: 223–231. 18097687
    • (2008) Med Microbiol Immunol , vol.197 , pp. 223-231
    • Stinski, M.F.1    Isomura, H.2
  • 42
    • 77952689297 scopus 로고    scopus 로고
    • Enhancerless Cytomegalovirus Is Capable of Establishing a Low-Level Maintenance Infection in Severely Immunodeficient Host Tissues but Fails in Exponential Growth
    • Podlech J, Pintea R, Kropp KA, Fink A, Lemmermann NAW, et al. (2010) Enhancerless Cytomegalovirus Is Capable of Establishing a Low-Level Maintenance Infection in Severely Immunodeficient Host Tissues but Fails in Exponential Growth. J Virol 84: 6254–6261. doi: 10.1128/JVI.00419-10 20375164
    • (2010) J Virol , vol.84 , pp. 6254-6261
    • Podlech, J.1    Pintea, R.2    Kropp, K.A.3    Fink, A.4    Lemmermann, N.A.W.5
  • 43
    • 0022371467 scopus 로고
    • A very strong enhancer is located upstream of an immediate early gene of human cytomegalovirus
    • Boshart M, Weber F, Jahn G, Dorsch-Hasler K, Fleckenstein B, et al. (1985) A very strong enhancer is located upstream of an immediate early gene of human cytomegalovirus. Cell 41: 521–530. 2985280
    • (1985) Cell , vol.41 , pp. 521-530
    • Boshart, M.1    Weber, F.2    Jahn, G.3    Dorsch-Hasler, K.4    Fleckenstein, B.5
  • 44
    • 0011720508 scopus 로고
    • A long and complex enhancer activates transcription of the gene coding for the highly abundant immediate early mRNA in murine cytomegalovirus
    • Dorsch-Häsler K, Keil GM, Weber F, Jasin M, Schaffner W, et al. (1985) A long and complex enhancer activates transcription of the gene coding for the highly abundant immediate early mRNA in murine cytomegalovirus. Proc Natl Acad Sci USA. pp. 8325–8329. 3001696
    • (1985) Proc Natl Acad Sci USA , pp. 8325-8329
    • Dorsch-Häsler, K.1    Keil, G.M.2    Weber, F.3    Jasin, M.4    Schaffner, W.5
  • 45
    • 0346786616 scopus 로고
    • Binding of transcription factors and creation of a large nucleoprotein complex on the human cytomegalovirus enhancer
    • Ghazal P, Lubon H, Fleckenstein B, Hennighausen L, (1987) Binding of transcription factors and creation of a large nucleoprotein complex on the human cytomegalovirus enhancer. Proc Natl Acad Sci U S A 84: 3658–3662. 3035545
    • (1987) Proc Natl Acad Sci U S A , vol.84 , pp. 3658-3662
    • Ghazal, P.1    Lubon, H.2    Fleckenstein, B.3    Hennighausen, L.4
  • 46
    • 1642277986 scopus 로고    scopus 로고
    • NF-KB and c-Jun-dependent regulation of human cytomegalovirus immediate-early gene enhancer/promoter in response to lipopolysaccharide and bacterial CpG-oligodeoxynucleotides in macrophage cell line RAW 264.7
    • Lee Y, Sohn WJ, Kim DS, Kwon HJ, (2004) NF-KB and c-Jun-dependent regulation of human cytomegalovirus immediate-early gene enhancer/promoter in response to lipopolysaccharide and bacterial CpG-oligodeoxynucleotides in macrophage cell line RAW 264.7. Eur J Biochem 271: 1094–1105. 15009188
    • (2004) Eur J Biochem , vol.271 , pp. 1094-1105
    • Lee, Y.1    Sohn, W.J.2    Kim, D.S.3    Kwon, H.J.4
  • 47
    • 84895747639 scopus 로고    scopus 로고
    • Viral enhancer mimicry of host innate-immune promoters
    • Kropp KA, Angulo A, Ghazal P, (2014) Viral enhancer mimicry of host innate-immune promoters. PLoS Pathog 10: e1003804. doi: 10.1371/journal.ppat.1003804 24516378
    • (2014) PLoS Pathog , vol.10
    • Kropp, K.A.1    Angulo, A.2    Ghazal, P.3
  • 48
    • 66949166017 scopus 로고    scopus 로고
    • A proviral role for CpG in cytomegalovirus infection
    • Iversen AC, Steinkjer B, Nilsen N, Bohnhorst J, Moen SH, et al. (2009) A proviral role for CpG in cytomegalovirus infection. J Immunol 182: 5672–5681. doi: 10.4049/jimmunol.0801268 19380814
    • (2009) J Immunol , vol.182 , pp. 5672-5681
    • Iversen, A.C.1    Steinkjer, B.2    Nilsen, N.3    Bohnhorst, J.4    Moen, S.H.5
  • 49
    • 0037133636 scopus 로고    scopus 로고
    • Virus self-improvement through inflammation: No pain, no gain
    • Mocarski ES, (2002) Virus self-improvement through inflammation: No pain, no gain. Proc Natl Acad Sci USA 99: 3362–3364. 11904398
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 3362-3364
    • Mocarski, E.S.1
  • 50
    • 0347949568 scopus 로고    scopus 로고
    • Neutrality of the canonical NF-kappa B-dependent pathway for human and murine cytomegalovirus transcription and replication in vitro
    • Benedict CA, Angulo A, Patterson G, Ha SW, Huang H, et al. (2004) Neutrality of the canonical NF-kappa B-dependent pathway for human and murine cytomegalovirus transcription and replication in vitro. J Virol 78: 741–750. 14694106
    • (2004) J Virol , vol.78 , pp. 741-750
    • Benedict, C.A.1    Angulo, A.2    Patterson, G.3    Ha, S.W.4    Huang, H.5
  • 51
    • 33748949778 scopus 로고    scopus 로고
    • Regulation of the transcription and replication cycle of human cytomegalovirus is insensitive to genetic elimination of the cognate NF-kappa B binding sites in the enhancer
    • Gustems M, Borst E, Benedict CA, Perez C, Messerle M, et al. (2006) Regulation of the transcription and replication cycle of human cytomegalovirus is insensitive to genetic elimination of the cognate NF-kappa B binding sites in the enhancer. J Virol 80: 9899–9904. 16973595
    • (2006) J Virol , vol.80 , pp. 9899-9904
    • Gustems, M.1    Borst, E.2    Benedict, C.A.3    Perez, C.4    Messerle, M.5
  • 52
    • 0036714265 scopus 로고    scopus 로고
    • Recombinant Gaussia luciferase. Overexpression, purification, and analytical application of a bioluminescent reporter for DNA hybridization
    • Verhaegen M, Christopoulos TK, (2002) Recombinant Gaussia luciferase. Overexpression, purification, and analytical application of a bioluminescent reporter for DNA hybridization. Anal Chem 74: 4378–4385. 12236345
    • (2002) Anal Chem , vol.74 , pp. 4378-4385
    • Verhaegen, M.1    Christopoulos, T.K.2
  • 53
    • 38749112547 scopus 로고    scopus 로고
    • A secreted luciferase for ex vivo monitoring of in vivo processes
    • Wurdinger T, Badr C, Pike L, de Kleine R, Weissleder R, et al. (2008) A secreted luciferase for ex vivo monitoring of in vivo processes. Nat Methods 5: 171–173. doi: 10.1038/nmeth.1177 18204457
    • (2008) Nat Methods , vol.5 , pp. 171-173
    • Wurdinger, T.1    Badr, C.2    Pike, L.3    de Kleine, R.4    Weissleder, R.5
  • 54
    • 79958095008 scopus 로고    scopus 로고
    • Temporal profiling of the coding and noncoding murine cytomegalovirus transcriptomes
    • Lacaze P, Forster T, Ross A, Kerr LE, Salvo-Chirnside E, et al. (2011) Temporal profiling of the coding and noncoding murine cytomegalovirus transcriptomes. J Virol 85: 6065–6076. doi: 10.1128/JVI.02341-10 21471238
    • (2011) J Virol , vol.85 , pp. 6065-6076
    • Lacaze, P.1    Forster, T.2    Ross, A.3    Kerr, L.E.4    Salvo-Chirnside, E.5
  • 55
    • 42249086779 scopus 로고    scopus 로고
    • Phenotypes of major immediate-early gene mutants of mouse cytomegalovirus
    • Busche A, Angulo A, Kay-Jackson P, Ghazal P, Messerle M, (2008) Phenotypes of major immediate-early gene mutants of mouse cytomegalovirus. Med Microbiol Immunol 197: 233–240. doi: 10.1007/s00430-008-0076-3 18239940
    • (2008) Med Microbiol Immunol , vol.197 , pp. 233-240
    • Busche, A.1    Angulo, A.2    Kay-Jackson, P.3    Ghazal, P.4    Messerle, M.5
  • 56
    • 0025974978 scopus 로고
    • Structure and expression of murine cytomegalovirus immediate-early gene 2
    • Messerle M, Keil GM, Koszinowski UH, (1991) Structure and expression of murine cytomegalovirus immediate-early gene 2. J Virol 65: 1638–1643. 1847480
    • (1991) J Virol , vol.65 , pp. 1638-1643
    • Messerle, M.1    Keil, G.M.2    Koszinowski, U.H.3
  • 57
    • 0041331693 scopus 로고    scopus 로고
    • Subcellular localization of Toll-like receptor 3 in human dendritic cells
    • Matsumoto M, Funami K, Tanabe M, Oshiumi H, Shingai M, et al. (2003) Subcellular localization of Toll-like receptor 3 in human dendritic cells. J Immunol 171: 3154–3162. 12960343
    • (2003) J Immunol , vol.171 , pp. 3154-3162
    • Matsumoto, M.1    Funami, K.2    Tanabe, M.3    Oshiumi, H.4    Shingai, M.5
  • 58
    • 47249083830 scopus 로고    scopus 로고
    • Functional characterization of murine interferon regulatory factor 5 (IRF-5) and its role in the innate antiviral response
    • Paun A, Reinert JT, Jiang Z, Medin C, Balkhi MY, et al. (2008) Functional characterization of murine interferon regulatory factor 5 (IRF-5) and its role in the innate antiviral response. J Biol Chem 283: 14295–14308. doi: 10.1074/jbc.M800501200 18332133
    • (2008) J Biol Chem , vol.283 , pp. 14295-14308
    • Paun, A.1    Reinert, J.T.2    Jiang, Z.3    Medin, C.4    Balkhi, M.Y.5
  • 59
    • 38549138306 scopus 로고    scopus 로고
    • Sensing of viral infection and activation of innate immunity by toll-like receptor 3
    • Vercammen E, Staal J, Beyaert R, (2008) Sensing of viral infection and activation of innate immunity by toll-like receptor 3. Clin Microbiol Rev 21: 13–25. doi: 10.1128/CMR.00022-07 18202435
    • (2008) Clin Microbiol Rev , vol.21 , pp. 13-25
    • Vercammen, E.1    Staal, J.2    Beyaert, R.3
  • 60
    • 84872077258 scopus 로고    scopus 로고
    • The role of UNC93B1 protein in surface localization of TLR3 receptor and in cell priming to nucleic acid agonists
    • Pohar J, Pirher N, Bencina M, Mancek-Keber M, Jerala R, (2013) The role of UNC93B1 protein in surface localization of TLR3 receptor and in cell priming to nucleic acid agonists. J Biol Chem 288: 442–454. doi: 10.1074/jbc.M112.413922 23166319
    • (2013) J Biol Chem , vol.288 , pp. 442-454
    • Pohar, J.1    Pirher, N.2    Bencina, M.3    Mancek-Keber, M.4    Jerala, R.5
  • 61
    • 0027423937 scopus 로고
    • Interferons inhibit onset of murine cytomegalovirus immediate-early gene transcription
    • Gribaudo G, Ravaglia S, Caliendo A, Cavallo R, Gariglio M, et al. (1993) Interferons inhibit onset of murine cytomegalovirus immediate-early gene transcription. Virology 197: 303–311. 8212566
    • (1993) Virology , vol.197 , pp. 303-311
    • Gribaudo, G.1    Ravaglia, S.2    Caliendo, A.3    Cavallo, R.4    Gariglio, M.5
  • 63
    • 84895771638 scopus 로고    scopus 로고
    • Reversible silencing of cytomegalovirus genomes by type I interferon governs virus latency
    • Dag F, Dolken L, Holzki J, Drabig A, Weingartner A, et al. (2014) Reversible silencing of cytomegalovirus genomes by type I interferon governs virus latency. PLoS Pathog 10: e1003962. doi: 10.1371/journal.ppat.1003962 24586165
    • (2014) PLoS Pathog , vol.10
    • Dag, F.1    Dolken, L.2    Holzki, J.3    Drabig, A.4    Weingartner, A.5
  • 64
    • 80053947344 scopus 로고    scopus 로고
    • Reversible Inhibition of Murine Cytomegalovirus Replication by Gamma Interferon (IFN-γ) in Primary Macrophages Involves a Primed Type I IFN-Signaling Subnetwork for Full Establishment of an Immediate-Early Antiviral State
    • Kropp KA, Robertson KA, Sing G, Rodriguez-Martin S, Blanc M, et al. (2011) Reversible Inhibition of Murine Cytomegalovirus Replication by Gamma Interferon (IFN-γ) in Primary Macrophages Involves a Primed Type I IFN-Signaling Subnetwork for Full Establishment of an Immediate-Early Antiviral State. J Virol 85: 10286–10299. doi: 10.1128/JVI.00373-11 21775459
    • (2011) J Virol , vol.85 , pp. 10286-10299
    • Kropp, K.A.1    Robertson, K.A.2    Sing, G.3    Rodriguez-Martin, S.4    Blanc, M.5
  • 66
    • 0025124527 scopus 로고
    • The palindromic series I repeats in the simian cytomegalovirus major immediate-early promoter behave as both strong basal enhancers and cyclic AMP response elements
    • Chang YN, Crawford S, Stall J, Rawlins DR, Jeang KT, et al. (1990) The palindromic series I repeats in the simian cytomegalovirus major immediate-early promoter behave as both strong basal enhancers and cyclic AMP response elements. J Virol 64: 264–277. 2152815
    • (1990) J Virol , vol.64 , pp. 264-277
    • Chang, Y.N.1    Crawford, S.2    Stall, J.3    Rawlins, D.R.4    Jeang, K.T.5
  • 67
    • 34249933862 scopus 로고    scopus 로고
    • Reversal of human cytomegalovirus major immediate-early enhancer/promoter silencing in quiescently infected cells via the cyclic AMP signaling pathway
    • Keller MJ, Wu AW, Andrews JI, McGonagill PW, Tibesar EE, et al. (2007) Reversal of human cytomegalovirus major immediate-early enhancer/promoter silencing in quiescently infected cells via the cyclic AMP signaling pathway. J Virol 81: 6669–6681. 17301150
    • (2007) J Virol , vol.81 , pp. 6669-6681
    • Keller, M.J.1    Wu, A.W.2    Andrews, J.I.3    McGonagill, P.W.4    Tibesar, E.E.5
  • 68
    • 69249202490 scopus 로고    scopus 로고
    • The CREB Site in the Proximal Enhancer Is Critical for Cooperative Interaction with the Other Transcription Factor Binding Sites To Enhance Transcription of the Major Intermediate-Early Genes in Human Cytomegalovirus-Infected Cells
    • Lashmit P, Wang SH, Li HM, Isomura H, Stinski MF, (2009) The CREB Site in the Proximal Enhancer Is Critical for Cooperative Interaction with the Other Transcription Factor Binding Sites To Enhance Transcription of the Major Intermediate-Early Genes in Human Cytomegalovirus-Infected Cells. J Virol 83: 8893–8904. doi: 10.1128/JVI.02239-08 19553322
    • (2009) J Virol , vol.83 , pp. 8893-8904
    • Lashmit, P.1    Wang, S.H.2    Li, H.M.3    Isomura, H.4    Stinski, M.F.5
  • 69
    • 78951478406 scopus 로고    scopus 로고
    • The Activator Protein 1 Binding Motifs within the Human Cytomegalovirus Major Immediate-Early Enhancer Are Functionally Redundant and Act in a Cooperative Manner with the NF-kappa B Sites during Acute Infection
    • Isern E, Gustems M, Messerle M, Borst E, Ghazal P, et al. (2011) The Activator Protein 1 Binding Motifs within the Human Cytomegalovirus Major Immediate-Early Enhancer Are Functionally Redundant and Act in a Cooperative Manner with the NF-kappa B Sites during Acute Infection. J Virol 85: 1732–1746. doi: 10.1128/JVI.01713-10 21106746
    • (2011) J Virol , vol.85 , pp. 1732-1746
    • Isern, E.1    Gustems, M.2    Messerle, M.3    Borst, E.4    Ghazal, P.5
  • 70
    • 22544446190 scopus 로고    scopus 로고
    • Two Sp1/Sp3 binding sites in the major immediate-early proximal enhancer of human cytomegalovirus have a significant role in viral replication
    • Isomura H, Stinski MF, Kudoh A, Daikoku T, Shirata N, et al. (2005) Two Sp1/Sp3 binding sites in the major immediate-early proximal enhancer of human cytomegalovirus have a significant role in viral replication. J Virol 79: 9597–9607. 16014922
    • (2005) J Virol , vol.79 , pp. 9597-9607
    • Isomura, H.1    Stinski, M.F.2    Kudoh, A.3    Daikoku, T.4    Shirata, N.5
  • 71
    • 84876515907 scopus 로고    scopus 로고
    • STRING v9.1: protein-protein interaction networks, with increased coverage and integration
    • Franceschini A, Szklarczyk D, Frankild S, Kuhn M, Simonovic M, et al. (2013) STRING v9.1: protein-protein interaction networks, with increased coverage and integration. Nucleic Acids Res 41: D808–815. doi: 10.1093/nar/gks1094 23203871
    • (2013) Nucleic Acids Res , vol.41 , pp. 808-815
    • Franceschini, A.1    Szklarczyk, D.2    Frankild, S.3    Kuhn, M.4    Simonovic, M.5
  • 72
    • 0029914073 scopus 로고    scopus 로고
    • Synergistic interactions between overlapping binding sites for the serum response factor and ELK-1 proteins mediate both basal enhancement and phorbol ester responsiveness of primate cytomegalovirus major immediate-early promoters in monocyte and T-lymphocyte cell types
    • Chan YJ, Chiou CJ, Huang Q, Hayward GS, (1996) Synergistic interactions between overlapping binding sites for the serum response factor and ELK-1 proteins mediate both basal enhancement and phorbol ester responsiveness of primate cytomegalovirus major immediate-early promoters in monocyte and T-lymphocyte cell types. J Virol 70: 8590–8605. 8970984
    • (1996) J Virol , vol.70 , pp. 8590-8605
    • Chan, Y.J.1    Chiou, C.J.2    Huang, Q.3    Hayward, G.S.4
  • 73
    • 14744292639 scopus 로고    scopus 로고
    • Ets-2 repressor factor recruits histone deacetylase to silence human cytomegalovirus immediate-early gene expression in non-permissive cells
    • Wright E, Bain M, Teague L, Murphy J, Sinclair J, (2005) Ets-2 repressor factor recruits histone deacetylase to silence human cytomegalovirus immediate-early gene expression in non-permissive cells. J Gen Virol 86: 535–544. 15722512
    • (2005) J Gen Virol , vol.86 , pp. 535-544
    • Wright, E.1    Bain, M.2    Teague, L.3    Murphy, J.4    Sinclair, J.5
  • 75
    • 0029072193 scopus 로고
    • Retinoid activation of retinoic acid receptors but not of retinoid X receptors promotes cellular differentiation and replication of human cytomegalovirus in embryonal cells
    • Angulo A, Suto C, Boehm MF, Heyman RA, Ghazal P, (1995) Retinoid activation of retinoic acid receptors but not of retinoid X receptors promotes cellular differentiation and replication of human cytomegalovirus in embryonal cells. J Virol 69: 3831–3837. 7745731
    • (1995) J Virol , vol.69 , pp. 3831-3837
    • Angulo, A.1    Suto, C.2    Boehm, M.F.3    Heyman, R.A.4    Ghazal, P.5
  • 76
    • 0030059150 scopus 로고    scopus 로고
    • Characterization of the sequences of the human cytomegalovirus enhancer that mediate differential regulation by natural and synthetic retinoids
    • Angulo A, Suto C, Heyman RA, Ghazal P, (1996) Characterization of the sequences of the human cytomegalovirus enhancer that mediate differential regulation by natural and synthetic retinoids. Mol Endocrinol 10: 781–793. 8813719
    • (1996) Mol Endocrinol , vol.10 , pp. 781-793
    • Angulo, A.1    Suto, C.2    Heyman, R.A.3    Ghazal, P.4
  • 77
    • 0031925675 scopus 로고    scopus 로고
    • Ligand induction of retinoic acid receptors alters an acute infection by murine cytomegalovirus
    • Angulo A, Chandraratna RA, LeBlanc JF, Ghazal P, (1998) Ligand induction of retinoic acid receptors alters an acute infection by murine cytomegalovirus. J Virol 72: 4589–4600. 9573222
    • (1998) J Virol , vol.72 , pp. 4589-4600
    • Angulo, A.1    Chandraratna, R.A.2    LeBlanc, J.F.3    Ghazal, P.4
  • 78
    • 14044257262 scopus 로고    scopus 로고
    • Cutting edge: all-trans retinoic acid down-regulates TLR2 expression and function
    • Liu PT, Krutzik SR, Kim J, Modlin RL, (2005) Cutting edge: all-trans retinoic acid down-regulates TLR2 expression and function. J Immunol 174: 2467–2470. 15728448
    • (2005) J Immunol , vol.174 , pp. 2467-2470
    • Liu, P.T.1    Krutzik, S.R.2    Kim, J.3    Modlin, R.L.4
  • 79
    • 84878958382 scopus 로고    scopus 로고
    • Synergy between RA and TLR3 promotes type I IFN-dependent apoptosis through upregulation of TRAIL pathway in breast cancer cells
    • Bernardo AR, Cosgaya JM, Aranda A, Jimenez-Lara AM, (2013) Synergy between RA and TLR3 promotes type I IFN-dependent apoptosis through upregulation of TRAIL pathway in breast cancer cells. Cell Death & Disease 4: e479.
    • (2013) Cell Death & Disease , vol.4
    • Bernardo, A.R.1    Cosgaya, J.M.2    Aranda, A.3    Jimenez-Lara, A.M.4
  • 80
    • 26444607929 scopus 로고    scopus 로고
    • Ligand recognition by RAR and RXR receptors: binding and selectivity
    • Sussman F, de Lera AR, (2005) Ligand recognition by RAR and RXR receptors: binding and selectivity. J Med Chem 48: 6212–6219. 16190748
    • (2005) J Med Chem , vol.48 , pp. 6212-6219
    • Sussman, F.1    de Lera, A.R.2
  • 81
    • 77953287029 scopus 로고    scopus 로고
    • A new cell-based innate immune receptor assay for the examination of receptor activity, ligand specificity, signalling pathways and the detection of pyrogens
    • Burger-Kentischer A, Abele IS, Finkelmeier D, Wiesmuller KH, Rupp S, (2010) A new cell-based innate immune receptor assay for the examination of receptor activity, ligand specificity, signalling pathways and the detection of pyrogens. J Immunol Methods 358: 93–103. doi: 10.1016/j.jim.2010.03.020 20385141
    • (2010) J Immunol Methods , vol.358 , pp. 93-103
    • Burger-Kentischer, A.1    Abele, I.S.2    Finkelmeier, D.3    Wiesmuller, K.H.4    Rupp, S.5
  • 82
    • 34447499052 scopus 로고    scopus 로고
    • Triggering the innate antiviral response through IRF-3 activation
    • Hiscott J, (2007) Triggering the innate antiviral response through IRF-3 activation. J Biol Chem 282: 15325–15329. 17395583
    • (2007) J Biol Chem , vol.282 , pp. 15325-15329
    • Hiscott, J.1
  • 83
    • 27744526416 scopus 로고    scopus 로고
    • Regulation of the type I IFN induction: a current view
    • Honda K, Yanai H, Takaoka A, Taniguchi T, (2005) Regulation of the type I IFN induction: a current view. Int Immunol 17: 1367–1378. 16214811
    • (2005) Int Immunol , vol.17 , pp. 1367-1378
    • Honda, K.1    Yanai, H.2    Takaoka, A.3    Taniguchi, T.4
  • 84
    • 0028348307 scopus 로고
    • Requirement for Transcription Factor Irf-1 in No Synthase Induction in Macrophages
    • Kamijo R, Harada H, Matsuyama T, Bosland M, Gerecitano J, et al. (1994) Requirement for Transcription Factor Irf-1 in No Synthase Induction in Macrophages. Science 263: 1612–1615. 7510419
    • (1994) Science , vol.263 , pp. 1612-1615
    • Kamijo, R.1    Harada, H.2    Matsuyama, T.3    Bosland, M.4    Gerecitano, J.5
  • 85
    • 0035968246 scopus 로고    scopus 로고
    • Virus-specific activation of a novel interferon regulatory factor, IRF-5, results in the induction of distinct interferon alpha genes
    • Barnes BJ, Moore PA, Pitha PM, (2001) Virus-specific activation of a novel interferon regulatory factor, IRF-5, results in the induction of distinct interferon alpha genes. J Biol Chem 276: 23382–23390. 11303025
    • (2001) J Biol Chem , vol.276 , pp. 23382-23390
    • Barnes, B.J.1    Moore, P.A.2    Pitha, P.M.3
  • 86
    • 38549096565 scopus 로고    scopus 로고
    • JASPAR, the open access database of transcription factor-binding profiles: new content and tools in the 2008 update
    • Bryne JC, Valen E, Tang MH, Marstrand T, Winther O, et al. (2008) JASPAR, the open access database of transcription factor-binding profiles: new content and tools in the 2008 update. Nucleic Acids Res 36: D102–106. 18006571
    • (2008) Nucleic Acids Res , vol.36 , pp. 102-106
    • Bryne, J.C.1    Valen, E.2    Tang, M.H.3    Marstrand, T.4    Winther, O.5
  • 87
    • 15044345461 scopus 로고    scopus 로고
    • Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors
    • Takaoka A, Yanai H, Kondo S, Duncan G, Negishi H, et al. (2005) Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors. Nature 434: 243–249. 15665823
    • (2005) Nature , vol.434 , pp. 243-249
    • Takaoka, A.1    Yanai, H.2    Kondo, S.3    Duncan, G.4    Negishi, H.5
  • 88
    • 34249792362 scopus 로고    scopus 로고
    • Murine Dendritic Cell Type I IFN Production Induced by Human IgG-RNA Immune Complexes Is IFN Regulatory Factor (IRF)5 and IRF7 Dependent and Is Required for IL-6 Production
    • Yasuda K, Richez C, Maciaszek JW, Agrawal N, Akira S, et al. (2007) Murine Dendritic Cell Type I IFN Production Induced by Human IgG-RNA Immune Complexes Is IFN Regulatory Factor (IRF)5 and IRF7 Dependent and Is Required for IL-6 Production. J Immunol 178: 6876–6885. 17513736
    • (2007) J Immunol , vol.178 , pp. 6876-6885
    • Yasuda, K.1    Richez, C.2    Maciaszek, J.W.3    Agrawal, N.4    Akira, S.5
  • 89
    • 7244242345 scopus 로고    scopus 로고
    • Global and distinct targets of IRF-5 and IRF-7 during innate response to viral infection
    • Barnes BJ, Richards J, Mancl M, Hanash S, Beretta L, et al. (2004) Global and distinct targets of IRF-5 and IRF-7 during innate response to viral infection. J Biol Chem 279: 45194–45207. 15308637
    • (2004) J Biol Chem , vol.279 , pp. 45194-45207
    • Barnes, B.J.1    Richards, J.2    Mancl, M.3    Hanash, S.4    Beretta, L.5
  • 90
    • 84878232476 scopus 로고    scopus 로고
    • The history of Toll-like receptors—redefining innate immunity
    • O'Neill LA, Golenbock D, Bowie AG, (2013) The history of Toll-like receptors—redefining innate immunity. Nat Rev Immunol 13: 453–460. doi: 10.1038/nri3446 23681101
    • (2013) Nat Rev Immunol , vol.13 , pp. 453-460
    • O'Neill, L.A.1    Golenbock, D.2    Bowie, A.G.3
  • 91
    • 84888014733 scopus 로고    scopus 로고
    • The tiers and dimensions of evasion of the type I interferon response by human cytomegalovirus
    • Amsler L, Verweij MC, DeFilippis VR, (2013) The tiers and dimensions of evasion of the type I interferon response by human cytomegalovirus. J Mol Biol 425: 4857–4871. doi: 10.1016/j.jmb.2013.08.023 24013068
    • (2013) J Mol Biol , vol.425 , pp. 4857-4871
    • Amsler, L.1    Verweij, M.C.2    DeFilippis, V.R.3
  • 93
    • 0038605236 scopus 로고    scopus 로고
    • NF-kappaB and virus infection: who controls whom
    • Santoro MG, Rossi A, Amici C, (2003) NF-kappaB and virus infection: who controls whom. EMBO J 22: 2552–2560. 12773372
    • (2003) EMBO J , vol.22 , pp. 2552-2560
    • Santoro, M.G.1    Rossi, A.2    Amici, C.3
  • 94
    • 77951288057 scopus 로고    scopus 로고
    • HIV-1 exploits innate signaling by TLR8 and DC-SIGN for productive infection of dendritic cells
    • Gringhuis SI, van der Vlist M, van den Berg LM, den Dunnen J, Litjens M, et al. (2010) HIV-1 exploits innate signaling by TLR8 and DC-SIGN for productive infection of dendritic cells. Nat Immunol 11: 419–426. doi: 10.1038/ni.1858 20364151
    • (2010) Nat Immunol , vol.11 , pp. 419-426
    • Gringhuis, S.I.1    van der Vlist, M.2    van den Berg, L.M.3    den Dunnen, J.4    Litjens, M.5
  • 95
    • 2442714139 scopus 로고    scopus 로고
    • Activation of the NF-kappa B pathway in human cytomegalovirus-infected cells is necessary for efficient transactivation of the major immediate-early promoter
    • DeMeritt IB, Milford LE, Yurochko AD, (2004) Activation of the NF-kappa B pathway in human cytomegalovirus-infected cells is necessary for efficient transactivation of the major immediate-early promoter. J Virol 78: 4498–4507. 15078930
    • (2004) J Virol , vol.78 , pp. 4498-4507
    • DeMeritt, I.B.1    Milford, L.E.2    Yurochko, A.D.3
  • 96
    • 32844462156 scopus 로고    scopus 로고
    • Prolonged activation of NF-kappaB by human cytomegalovirus promotes efficient viral replication and late gene expression
    • DeMeritt IB, Podduturi JP, Tilley AM, Nogalski MT, Yurochko AD, (2006) Prolonged activation of NF-kappaB by human cytomegalovirus promotes efficient viral replication and late gene expression. Virology 346: 15–31. 16303162
    • (2006) Virology , vol.346 , pp. 15-31
    • DeMeritt, I.B.1    Podduturi, J.P.2    Tilley, A.M.3    Nogalski, M.T.4    Yurochko, A.D.5
  • 97
    • 77950855886 scopus 로고    scopus 로고
    • The Elk-1 and Serum Response Factor Binding Sites in the Major Immediate-Early Promoter of Human Cytomegalovirus Are Required for Efficient Viral Replication in Quiescent Cells and Compensate for Inactivation of the NF-κB Sites in Proliferating Cells
    • Caposio P, Luganini A, Bronzini M, Landolfo S, Gribaudo G, (2010) The Elk-1 and Serum Response Factor Binding Sites in the Major Immediate-Early Promoter of Human Cytomegalovirus Are Required for Efficient Viral Replication in Quiescent Cells and Compensate for Inactivation of the NF-κB Sites in Proliferating Cells. J Virol 84: 4481–4493. doi: 10.1128/JVI.02141-09 20147408
    • (2010) J Virol , vol.84 , pp. 4481-4493
    • Caposio, P.1    Luganini, A.2    Bronzini, M.3    Landolfo, S.4    Gribaudo, G.5
  • 99
    • 84878422067 scopus 로고    scopus 로고
    • The SOX gene family: function and regulation in testis determination and male fertility maintenance
    • Jiang T, Hou CC, She ZY, Yang WX, (2013) The SOX gene family: function and regulation in testis determination and male fertility maintenance. Mol Biol Rep 40: 2187–2194. doi: 10.1007/s11033-012-2279-3 23184044
    • (2013) Mol Biol Rep , vol.40 , pp. 2187-2194
    • Jiang, T.1    Hou, C.C.2    She, Z.Y.3    Yang, W.X.4
  • 100
    • 0028303478 scopus 로고
    • The transcription factor YY1 binds to negative regulatory elements in the human cytomegalovirus major immediate early enhancer/promoter and mediates repression in nonpermissive cells
    • Liu R, Baillie J, Sissons JGP, Sinclair JH, (1994) The transcription factor YY1 binds to negative regulatory elements in the human cytomegalovirus major immediate early enhancer/promoter and mediates repression in nonpermissive cells. Nucleic Acids Research 22: 2453–2459. 8041605
    • (1994) Nucleic Acids Research , vol.22 , pp. 2453-2459
    • Liu, R.1    Baillie, J.2    Sissons, J.G.P.3    Sinclair, J.H.4
  • 101
    • 20144388162 scopus 로고    scopus 로고
    • Two gamma interferon-activated site-like elements in the human cytomegalovirus major immediate-early promoter/enhancer are important for viral replication
    • Netterwald J, Yang S, Wang W, Ghanny S, Cody M, et al. (2005) Two gamma interferon-activated site-like elements in the human cytomegalovirus major immediate-early promoter/enhancer are important for viral replication. J Virol 79: 5035–5046. 15795289
    • (2005) J Virol , vol.79 , pp. 5035-5046
    • Netterwald, J.1    Yang, S.2    Wang, W.3    Ghanny, S.4    Cody, M.5
  • 102
    • 0029910215 scopus 로고    scopus 로고
    • Synergistic Activation of Interleukin-8 Gene Transcription by All-trans-retinoic Acid and Tumor Necrosis Factor-alpha Involves the Transcription Factor NF-kappa B
    • de Martin R, (1996) Synergistic Activation of Interleukin-8 Gene Transcription by All-trans-retinoic Acid and Tumor Necrosis Factor-alpha Involves the Transcription Factor NF-kappa B. J Biol Chem 271: 26954–26961. 8900181
    • (1996) J Biol Chem , vol.271 , pp. 26954-26961
    • de Martin, R.1
  • 103
    • 0030588140 scopus 로고    scopus 로고
    • Cloning of human lymphocyte-specific interferon regulatory factor (hLSIRF/hIRF4) and mapping of the gene to 6p23-p25
    • Grossman A, Mittrucker HW, Nicholl J, Suzuki A, Chung S, et al. (1996) Cloning of human lymphocyte-specific interferon regulatory factor (hLSIRF/hIRF4) and mapping of the gene to 6p23-p25. Genomics 37: 229–233. 8921401
    • (1996) Genomics , vol.37 , pp. 229-233
    • Grossman, A.1    Mittrucker, H.W.2    Nicholl, J.3    Suzuki, A.4    Chung, S.5
  • 104
    • 18644374446 scopus 로고    scopus 로고
    • Mutations in IRF6 cause Van der Woude and popliteal pterygium syndromes
    • Kondo S, Schutte BC, Richardson RJ, Bjork BC, Knight AS, et al. (2002) Mutations in IRF6 cause Van der Woude and popliteal pterygium syndromes. Nat Genet 32: 285–289. 12219090
    • (2002) Nat Genet , vol.32 , pp. 285-289
    • Kondo, S.1    Schutte, B.C.2    Richardson, R.J.3    Bjork, B.C.4    Knight, A.S.5
  • 105
    • 84896347326 scopus 로고    scopus 로고
    • Interferon regulatory factor 5 and autoimmune lupus
    • Xu WD, Pan HF, Xu Y, Ye DQ, (2013) Interferon regulatory factor 5 and autoimmune lupus. Expert Rev Mol Med 15: e6. doi: 10.1017/erm.2013.7 23883595
    • (2013) Expert Rev Mol Med , vol.15
    • Xu, W.D.1    Pan, H.F.2    Xu, Y.3    Ye, D.Q.4
  • 106
    • 20444380445 scopus 로고    scopus 로고
    • The interferon regulatory factor, IRF5, is a central mediator of toll-like receptor 7 signaling
    • Schoenemeyer A, Barnes BJ, Mancl ME, Latz E, Goutagny N, et al. (2005) The interferon regulatory factor, IRF5, is a central mediator of toll-like receptor 7 signaling. J Biol Chem 280: 17005–17012. 15695821
    • (2005) J Biol Chem , vol.280 , pp. 17005-17012
    • Schoenemeyer, A.1    Barnes, B.J.2    Mancl, M.E.3    Latz, E.4    Goutagny, N.5
  • 107
    • 77951260924 scopus 로고    scopus 로고
    • The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors
    • Kawai T, Akira S, (2010) The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. Nat Immunol 11: 373–384. doi: 10.1038/ni.1863 20404851
    • (2010) Nat Immunol , vol.11 , pp. 373-384
    • Kawai, T.1    Akira, S.2
  • 108
    • 32944464648 scopus 로고    scopus 로고
    • Pathogen recognition and innate immunity
    • Akira S, Uematsu S, Takeuchi O, (2006) Pathogen recognition and innate immunity. Cell 124: 783–801. 16497588
    • (2006) Cell , vol.124 , pp. 783-801
    • Akira, S.1    Uematsu, S.2    Takeuchi, O.3
  • 109
    • 34247590795 scopus 로고    scopus 로고
    • Rotavirus NSP1 inhibits expression of type I interferon by antagonizing the function of interferon regulatory factors IRF3, IRF5, and IRF7
    • Barro M, Patton JT, (2007) Rotavirus NSP1 inhibits expression of type I interferon by antagonizing the function of interferon regulatory factors IRF3, IRF5, and IRF7. J Virol 81: 4473–4481. 17301153
    • (2007) J Virol , vol.81 , pp. 4473-4481
    • Barro, M.1    Patton, J.T.2
  • 110
    • 35348884876 scopus 로고    scopus 로고
    • Manipulation of the toll-like receptor 7 signaling pathway by Epstein-Barr virus
    • Martin HJ, Lee JM, Walls D, Hayward SD, (2007) Manipulation of the toll-like receptor 7 signaling pathway by Epstein-Barr virus. J Virol 81: 9748–9758. 17609264
    • (2007) J Virol , vol.81 , pp. 9748-9758
    • Martin, H.J.1    Lee, J.M.2    Walls, D.3    Hayward, S.D.4
  • 111
    • 85047689512 scopus 로고    scopus 로고
    • A functional interferon regulatory factor-1 (IRF-1)-binding site in the upstream regulatory region (URR) of human papillomavirus type 16
    • Arany I, Grattendick KJ, Whitehead WE, Ember IA, Tyring SK, (2003) A functional interferon regulatory factor-1 (IRF-1)-binding site in the upstream regulatory region (URR) of human papillomavirus type 16. Virology 310: 280–286. 12781715
    • (2003) Virology , vol.310 , pp. 280-286
    • Arany, I.1    Grattendick, K.J.2    Whitehead, W.E.3    Ember, I.A.4    Tyring, S.K.5
  • 112
    • 0036566779 scopus 로고    scopus 로고
    • Functional characterization of the interferon regulatory element in the enhancer 1 region of the hepatitis B virus genome
    • Alcantara FF, Tang H, McLachlan A, (2002) Functional characterization of the interferon regulatory element in the enhancer 1 region of the hepatitis B virus genome. Nucleic Acids Res 30: 2068–2075. 11972347
    • (2002) Nucleic Acids Res , vol.30 , pp. 2068-2075
    • Alcantara, F.F.1    Tang, H.2    McLachlan, A.3
  • 113
    • 41149122048 scopus 로고    scopus 로고
    • IRF-1 is required for full NF-kappaB transcriptional activity at the human immunodeficiency virus type 1 long terminal repeat enhancer
    • Sgarbanti M, Remoli AL, Marsili G, Ridolfi B, Borsetti A, et al. (2008) IRF-1 is required for full NF-kappaB transcriptional activity at the human immunodeficiency virus type 1 long terminal repeat enhancer. J Virol 82: 3632–3641. doi: 10.1128/JVI.00599-07 18216101
    • (2008) J Virol , vol.82 , pp. 3632-3641
    • Sgarbanti, M.1    Remoli, A.L.2    Marsili, G.3    Ridolfi, B.4    Borsetti, A.5
  • 114
    • 84875065899 scopus 로고    scopus 로고
    • IRF-3, IRF-5, and IRF-7 coordinately regulate the type I IFN response in myeloid dendritic cells downstream of MAVS signaling
    • Lazear HM, Lancaster A, Wilkins C, Suthar MS, Huang A, et al. (2013) IRF-3, IRF-5, and IRF-7 coordinately regulate the type I IFN response in myeloid dendritic cells downstream of MAVS signaling. PLoS Pathog 9: e1003118. doi: 10.1371/journal.ppat.1003118 23300459
    • (2013) PLoS Pathog , vol.9
    • Lazear, H.M.1    Lancaster, A.2    Wilkins, C.3    Suthar, M.S.4    Huang, A.5
  • 115
    • 41849123062 scopus 로고    scopus 로고
    • Uncovering a macrophage transcriptional program by integrating evidence from motif scanning and expression dynamics
    • Ramsey SA, Klemm SL, Zak DE, Kennedy KA, Thorsson V, et al. (2008) Uncovering a macrophage transcriptional program by integrating evidence from motif scanning and expression dynamics. PLoS Comput Biol 4: e1000021. doi: 10.1371/journal.pcbi.1000021 18369420
    • (2008) PLoS Comput Biol , vol.4
    • Ramsey, S.A.1    Klemm, S.L.2    Zak, D.E.3    Kennedy, K.A.4    Thorsson, V.5
  • 116
    • 84878604299 scopus 로고    scopus 로고
    • The synergy in cytokine production through MyD88-TRIF pathways is co-ordinated with ERK phosphorylation in macrophages
    • Suet Ting Tan R, Lin B, Liu Q, Tucker-Kellogg L, Ho B, et al. (2013) The synergy in cytokine production through MyD88-TRIF pathways is co-ordinated with ERK phosphorylation in macrophages. Immunol Cell Biol 91: 377–387. doi: 10.1038/icb.2013.13 23567895
    • (2013) Immunol Cell Biol , vol.91 , pp. 377-387
    • Suet Ting Tan, R.1    Lin, B.2    Liu, Q.3    Tucker-Kellogg, L.4    Ho, B.5
  • 117
    • 0037075551 scopus 로고    scopus 로고
    • RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems
    • Kobayashi K, Inohara N, Hernandez LD, Galan JE, Nunez G, et al. (2002) RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems. Nature 416: 194–199. 11894098
    • (2002) Nature , vol.416 , pp. 194-199
    • Kobayashi, K.1    Inohara, N.2    Hernandez, L.D.3    Galan, J.E.4    Nunez, G.5
  • 118
    • 0035912832 scopus 로고    scopus 로고
    • Global modulation of cellular transcription by human cytomegalovirus is initiated by viral glycoprotein B
    • Simmen KA, Singh J, Luukkonen BG, Lopper M, Bittner A, et al. (2001) Global modulation of cellular transcription by human cytomegalovirus is initiated by viral glycoprotein B. Proc Natl Acad Sci U S A 98: 7140–7145. 11390970
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 7140-7145
    • Simmen, K.A.1    Singh, J.2    Luukkonen, B.G.3    Lopper, M.4    Bittner, A.5
  • 119
    • 0032931994 scopus 로고    scopus 로고
    • Engagement of the cellular receptor for glycoprotein B of human cytomegalovirus activates the interferon-responsive pathway
    • Boyle KA, Pietropaolo RL, Compton T, (1999) Engagement of the cellular receptor for glycoprotein B of human cytomegalovirus activates the interferon-responsive pathway. Mol Cell Biol 19: 3607–3613. 10207084
    • (1999) Mol Cell Biol , vol.19 , pp. 3607-3613
    • Boyle, K.A.1    Pietropaolo, R.L.2    Compton, T.3
  • 120
    • 84873810684 scopus 로고    scopus 로고
    • The herpes simplex virus 1-encoded envelope glycoprotein B activates NF-kappaB through the Toll-like receptor 2 and MyD88/TRAF6-dependent signaling pathway
    • Cai M, Li M, Wang K, Wang S, Lu Q, et al. (2013) The herpes simplex virus 1-encoded envelope glycoprotein B activates NF-kappaB through the Toll-like receptor 2 and MyD88/TRAF6-dependent signaling pathway. PLoS One 8: e54586. doi: 10.1371/journal.pone.0054586 23382920
    • (2013) PLoS One , vol.8
    • Cai, M.1    Li, M.2    Wang, K.3    Wang, S.4    Lu, Q.5
  • 122
    • 0032127279 scopus 로고    scopus 로고
    • Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function
    • Adachi O, Kawai T, Takeda K, Matsumoto M, Tsutsui H, et al. (1998) Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function. Immunity 9: 143–150. 9697844
    • (1998) Immunity , vol.9 , pp. 143-150
    • Adachi, O.1    Kawai, T.2    Takeda, K.3    Matsumoto, M.4    Tsutsui, H.5
  • 124
    • 0032789093 scopus 로고    scopus 로고
    • Systematic excision of vector sequences from the BAC-cloned herpesvirus genome during virus reconstitution
    • Wagner M, Jonjic S, Koszinowski UH, Messerle M, (1999) Systematic excision of vector sequences from the BAC-cloned herpesvirus genome during virus reconstitution. J Virol 73: 7056–7060. 10400809
    • (1999) J Virol , vol.73 , pp. 7056-7060
    • Wagner, M.1    Jonjic, S.2    Koszinowski, U.H.3    Messerle, M.4
  • 125
    • 0034469629 scopus 로고    scopus 로고
    • The major immediate-early gene ie3 of mouse cytomegalovirus is essential for viral growth
    • Angulo A, Ghazal P, Messerle M, (2000) The major immediate-early gene ie3 of mouse cytomegalovirus is essential for viral growth. J Virol 74: 11129–11136. 11070009
    • (2000) J Virol , vol.74 , pp. 11129-11136
    • Angulo, A.1    Ghazal, P.2    Messerle, M.3
  • 126
    • 0035308590 scopus 로고    scopus 로고
    • A highly efficient Escherichia coli-based chromosome engineering system adapted for recombinogenic targeting and subcloning of BAC DNA
    • Lee EC, Yu D, Martinez de Velasco J, Tessarollo L, Swing DA, et al. (2001) A highly efficient Escherichia coli-based chromosome engineering system adapted for recombinogenic targeting and subcloning of BAC DNA. Genomics 73: 56–65. 11352566
    • (2001) Genomics , vol.73 , pp. 56-65
    • Lee, E.C.1    Yu, D.2    Martinez de Velasco, J.3    Tessarollo, L.4    Swing, D.A.5
  • 127
    • 0031434397 scopus 로고    scopus 로고
    • Cloning and mutagenesis of a herpesvirus genome as an infectious bacterial artificial chromosome
    • Messerle M, Crnkovic I, Hammerschmidt W, Ziegler H, Koszinowski UH, (1997) Cloning and mutagenesis of a herpesvirus genome as an infectious bacterial artificial chromosome. Proc Natl Acad Sci USA 94: 14759–14763. 9405686
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 14759-14763
    • Messerle, M.1    Crnkovic, I.2    Hammerschmidt, W.3    Ziegler, H.4    Koszinowski, U.H.5
  • 128
    • 34248559599 scopus 로고    scopus 로고
    • Gene splicing and mutagenesis by PCR-driven overlap extension
    • Heckman KL, Pease LR, (2007) Gene splicing and mutagenesis by PCR-driven overlap extension. Nature protocols 2: 924–932. 17446874
    • (2007) Nature protocols , vol.2 , pp. 924-932
    • Heckman, K.L.1    Pease, L.R.2
  • 129
    • 26644453335 scopus 로고    scopus 로고
    • Simple and highly efficient BAC recombineering using galK selection
    • Warming S, Costantino N, (2005) Simple and highly efficient BAC recombineering using galK selection. Nucleic Acids Research 33: 1–12. 15640442
    • (2005) Nucleic Acids Research , vol.33 , pp. 1-12
    • Warming, S.1    Costantino, N.2
  • 132
    • 1842588435 scopus 로고    scopus 로고
    • The Ribonucleotide Reductase R1 Homolog of Murine Cytomegalovirus Is Not a Functional Enzyme Subunit but Is Required for Pathogenesis
    • Lembo D, Donalisio M, Hofer A, Cornaglia M, Brune W, et al. (2004) The Ribonucleotide Reductase R1 Homolog of Murine Cytomegalovirus Is Not a Functional Enzyme Subunit but Is Required for Pathogenesis. J Virol 78: 4278–4288. 15047841
    • (2004) J Virol , vol.78 , pp. 4278-4288
    • Lembo, D.1    Donalisio, M.2    Hofer, A.3    Cornaglia, M.4    Brune, W.5
  • 133
    • 34250159524 scopus 로고    scopus 로고
    • Genome-wide mapping of in vivo protein-DNA interactions
    • Johnson DS, Mortazavi A, Myers RM, Wold B, (2007) Genome-wide mapping of in vivo protein-DNA interactions. Science 316: 1497–1502. 17540862
    • (2007) Science , vol.316 , pp. 1497-1502
    • Johnson, D.S.1    Mortazavi, A.2    Myers, R.M.3    Wold, B.4
  • 134
    • 84863654457 scopus 로고    scopus 로고
    • Psip1/Ledgf p52 binds methylated histone H3K36 and splicing factors and contributes to the regulation of alternative splicing
    • Pradeepa MM, Sutherland HG, Ule J, Grimes GR, Bickmore WA, (2012) Psip1/Ledgf p52 binds methylated histone H3K36 and splicing factors and contributes to the regulation of alternative splicing. PLoS Genet 8: e1002717. doi: 10.1371/journal.pgen.1002717 22615581
    • (2012) PLoS Genet , vol.8
    • Pradeepa, M.M.1    Sutherland, H.G.2    Ule, J.3    Grimes, G.R.4    Bickmore, W.A.5
  • 136
    • 34447257655 scopus 로고    scopus 로고
    • Murine cytomegalovirus major immediate-early enhancer region operating as a genetic switch in bidirectional gene pair transcription
    • Simon CO, Kuhnapfel B, Reddehase MJ, Grzimek NKA, (2007) Murine cytomegalovirus major immediate-early enhancer region operating as a genetic switch in bidirectional gene pair transcription. J Virol 81: 7805–7810. 17494084
    • (2007) J Virol , vol.81 , pp. 7805-7810
    • Simon, C.O.1    Kuhnapfel, B.2    Reddehase, M.J.3    Grzimek, N.K.A.4
  • 137
    • 10644292437 scopus 로고    scopus 로고
    • Role for tumor necrosis factor alpha in murine cytomegalovirus transcriptional reactivation in latently infected lungs
    • Simon CO, Seckert CK, Dreis D, Reddehase MJ, Grzimek NK, (2005) Role for tumor necrosis factor alpha in murine cytomegalovirus transcriptional reactivation in latently infected lungs. J Virol 79: 326–340. 15596827
    • (2005) J Virol , vol.79 , pp. 326-340
    • Simon, C.O.1    Seckert, C.K.2    Dreis, D.3    Reddehase, M.J.4    Grzimek, N.K.5
  • 138
    • 0000541109 scopus 로고
    • An extension of Shapiro and Wilk's W test for normality to large samples
    • Royston J, (1982) An extension of Shapiro and Wilk's W test for normality to large samples. Applied Statistics 31: 115–124.
    • (1982) Applied Statistics , vol.31 , pp. 115-124
    • Royston, J.1
  • 139
    • 0002794255 scopus 로고
    • Sample Criteria for Testing Outlying Observations
    • Grubbs FE, (1950) Sample Criteria for Testing Outlying Observations. Ann Math Stat 21: 27–58.
    • (1950) Ann Math Stat , vol.21 , pp. 27-58
    • Grubbs, F.E.1


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