Functional characterization of the interferon regulatory element in the enhancer 1 region of the hepatitis B virus genome

Nucleic Acids Research

Volumn 30, Issue 9, 2002, Pages 2068-2075

  Alcantara, Flavio F ^a   Tang, Hong ^a,b   McLachlan, Alan ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b SICHUAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA1 INTERFERON; INTERFERON REGULATORY FACTOR 1; INTERFERON REGULATORY FACTOR 7; NUCLEOTIDE;

ARTICLE; CELL CULTURE; CONTROLLED STUDY; DNA RESPONSIVE ELEMENT; ENHANCER REGION; GENE CONSTRUCT; GENE FUNCTION; HEPATITIS B VIRUS; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; TRANSCRIPTION INITIATION; VIRUS GENOME; VIRUS REPLICATION; VIRUS TRANSCRIPTION;

ANIMALIA; DNA VIRUSES; HEPATITIS B VIRUS;

EID: 0036566779     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/30.9.2068     Document Type: Article

References (69)

1. Persistent infection of humans with hepatitis B virus: Mechanisms and consequences
2. The molecular biology of the hepatitis B viruses
3. Hepatocellular carcinoma and hepatitis B virus-a prospective study of 22707 men in Taiwan
4. Hepatitis B virus: The major etiology of hepatocellular carcinoma
5. Chronic hepatitis B virus infection: Treatment strategies for the next millenium
6. Current treatment strategies for chronic hepatitis B and C
7. The treatment of chronic viral hepatitis
8. Long-term follow-up of HBeAg-positive patients treated with interferon alfa for chronic hepatitis B
9. The treatment effect of alpha interferon in chronic hepatitis B is independent of pre-treatment variables. Results based on individual patient data from 10 clinical controlled trials
10. Clearance of chronic hepatitis B virus infection in young children after alpha interferon treatment
11. Genomic variations in the hepatitis B core gene: A possible factor influencing response to interferon alfa treatment
12. Transcriptional control of hepadnavirus gene expression
13. Regulation of hepatitis B virus gene expression
14. Preferred translation of human hepatitis B virus polymerase from core protein- but not from precore protein-specific transcript
15. Polymerase gene products of hepatitis B viruses are required for genomic RNA packaging as well as for reverse transcription
16. A short cis-acting sequence is required for hepatitis B virus pregenome encapsidation and sufficient for packaging of foreign RNA
17. The P gene product of hepatitis B virus is required as a structural component for genomic RNA encapsidation
18. Replication strategy of human hepatitis B virus
19. Electron and immunoelectron microscopic study of Dane particle formation in chronic hepatitis B virus infection
20. Morphologic, immunohistochemical and ultrastructural studies of the production of hepatitis B virus in vitro
21. Electron microscopic studies of Dane particles in hepatocytes with special reference to intracellular development of Dane particles and their relation with HBeAg in serum
22. Transcriptional regulation of hepatitis B virus by nuclear hormone receptors is a critical determinant of viral tropism
23. p48 (ISGF-3γ) is involved in interferon-α-induced suppression of hepatitis B virus enhancer-1 activity
24. Crystal structure of an IRF-DNA complex reveals novel DNA recognition and cooperative binding to a tandem repeat of core sequences
25. Lack of a role of the interferon-stimulated response element-like region in interferon α-induced suppression of hepatitis B virus in vitro
26. Interferon-induced nuclear factors that bind a shared promoter element correlate with positive and negative transcriptional control
27. Recognition DNA sequences of interferon regulatory factor 1 (IRF-1) and IRF-2, regulators of cell growth and the interferon system
28. Interferon-alpha regulates nuclear translocation and DNA-binding affinity of ISGF3, a multimeric transcriptional activator
29. Differential viral induction of distinct interferon-alpha genes by positive feedback through interferon regulatory factor-7
30. Structurally similar but functionally distinct factors, IRF-1 and IRF-2, bind to the same regulatory elements of IFN and IFN-inducible genes
31. Excretion of hepatitis B surface antigen particles from mouse cells transformed with cloned viral DNA
32. Differentiation specific transcriptional regulation of the hepatitis B virus large surface antigen gene in human hepatoma cell lines
33. Characterization of the minimal elements of the hepatitis B virus large surface antigen promoter
34. Virus infection induces the assembly of coordinately activated transcription factors on the IFN-beta enhancer in vivo
35. Interferon-induced transcription of a gene encoding a 15-kDa protein depends on an upstream enhancer element
36. Stat2 is a transcriptional activator that requires sequence-specific contacts provided by stat1 and p48 for stable interaction with DNA
37. A truncated form of the IRF-2 transcription factor has the properties of a postinduction repressor of interferon-beta gene expression
38. DNA sequencing with chain-terminating inhibitors
39. Mutational analysis of interferon (IFN) regulatory factors 1 and 2. Effects on the induction of IFN-beta gene expression
40. Amphotropic retrovirus vector system for human cell gene transfer
41. A new technique for the assay of infectivity of human adenovirus 5 DNA
42. Members of the nuclear receptor superfamily regulate transcription from the hepatitis B virus nucleocapsid promoter
43. Firefly luciferase gene: Structure and expression in mammalian cells
44. Expression of hepatitis B virus surface and core antigens: Influences of pre-s and precore sequences
45. Morphogenetic and regulatory effects of mutations in the envelope proteins of an avian hepadnavirus
46. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
47. Interactions between nuclear factors and the hepatitis B virus enhancer
48. Cellular factors that interact with the hepatitis B virus enhancer
49. p53 binds and represses the HBV enhancer: An adjacent enhancer element can reverse the transcription effect of p53
50. Type I interferons inhibit hepatitis B virus replication and induce hepatocellular gene expression in cultured liver cells
51. Effect of interferon alpha on hepatitis B virus replication and gene expression in transiently transfected human hepatoma cells
52. Interferon inhibits hepatitis B virus replication in a stable expression system of transfected viral DNA
53. Relative sensitivity of hepatitis B virus and other hepatotropic viruses to the antiviral effects of cytokines
54. The growing family of interferon regulatory factors
55. Expression of the hepatitis B virus X gene in mammalian cells
56. Identification of a promoter element located upstream from the hepatitis B virus X gene
57. Regulation of the hepatitis B virus gene expression by the enhancer element I
58. Isolation of a recombinant copy of the gene encoding C/EBP
59. Regulation of hepatitis B virus ENI activity by hepatocyte-enriched transcription factor HNF3
60. Hepatitis B virus enhancer binds and is activated by the hepatocyte nuclear factor 3
61. Functional interaction of nuclear factors EF-C, HNF-4 and RXRα with hepatitis B virus enhancer I
62. Retinoid X receptor RXRα binds to and trans-activates the hepatitis B virus enhancer
63. Retinoid X receptor α transactivates the hepatitis B virus enhancer 1 element by forming a heterodimeric complex with the peroxisome proliferator-activated receptor
64. RFX1 is identical to enhancer factor C and functions as a transactivator of the hepatitis B virus enhancer
65. Binding of nuclear factor EF-C to a functional domain of the hepatitis B virus enhancer region
66. HBV X protein alters the DNA binding specificity of CREB and ATF-2 by protein-protein interactions