Viral mediated redirection of NEMO/IKKγ to autophagosomes curtails the inflammatory cascade

PLoS Pathogens

Volumn 8, Issue 2, 2012, Pages

  Fliss, Patricia M ^a,b   Jowers, Tali Pechenick ^c   Brinkmann, Melanie M ^d   Holstermann, Barbara ^a   Mack, Claudia ^b,e   Dickinson, Paul ^c   Hohenberg, Heinrich ^a   Ghazal, Peter ^c   Brune, Wolfram ^a,b  

^a LEIBNIZ INSTITUTE FOR EXPERIMENTAL VIROLOGY   (Germany)

^b ROBERT KOCH INSTITUTE   (Germany)

^c UNIVERSITY OF EDINBURGH   (United Kingdom)

^d HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

^e UNIVERSITY OF FREIBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

I KAPPA B ALPHA; I KAPPA B KINASE ALPHA; I KAPPA B KINASE BETA; I KAPPA B KINASE GAMMA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 1; M45 PROTEIN; MICROTUBULE ASSOCIATED PROTEIN; MICROTUBULE ASSOCIATED PROTEIN LIGHT CHAIN 3; MITOGEN ACTIVATED PROTEIN KINASE P38; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 9; TRANSCRIPTION FACTOR RELA; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; UNCLASSIFIED DRUG; VIRUS PROTEIN; I KAPPA B KINASE; INTERLEUKIN 1BETA; NEMO PROTEIN, MOUSE; SIGNAL PEPTIDE; TOLL LIKE RECEPTOR;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RESPONSE; CYTOMEGALOVIRUS; HUMAN; HUMAN CELL; INFLAMMATION; LYSOSOME; MOUSE; NONHUMAN; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; ANIMAL; CELL STRAIN 3T3; DRUG ANTAGONISM; IMMUNOLOGY; METABOLISM; MUROMEGALOVIRUS; PHAGOSOME; SIGNAL TRANSDUCTION;

MURID HERPESVIRUS 1;

ANIMALS; AUTOPHAGY; I-KAPPA B KINASE; INFLAMMATION; INTERLEUKIN-1BETA; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MUROMEGALOVIRUS; NF-KAPPA B; NIH 3T3 CELLS; PHAGOSOMES; RECEPTORS, INTERLEUKIN-1; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84860901212     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1002517     Document Type: Article

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