The Herpes Simplex Virus 1-Encoded Envelope Glycoprotein B Activates NF-κB through the Toll-Like Receptor 2 and MyD88/TRAF6-Dependent Signaling Pathway

PLoS ONE

Volumn 8, Issue 1, 2013, Pages

  Cai, Mingsheng ^b,c,d   Li, Meili ^c   Wang, Kezhen ^a,b   Wang, Shuai ^a,b   Lu, Qiong ^e   Yan, Jinghua ^e   Mossman, Karen L ^f   Lin, Rongtuan ^g   Zheng, Chunfu ^a,b  

^a SOOCHOW UNIVERSITY   (China)

^b WUHAN INSTITUTE OF VIROLOGY   (China)

^c GUANGZHOU MEDICAL UNIVERSITY   (China)

^d Foshan Science and Technology University ^*  (China)

^e INSTITUTE OF MICROBIOLOGY   (China)

^f MCMASTER UNIVERSITY   (Canada)

^g MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CD14 ANTIGEN; GLYCOPROTEIN B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; MYELOID DIFFERENTIATION FACTOR 88; PROTEIN ANTIBODY; TOLL LIKE RECEPTOR 1; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 6; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6;

ANTIBODY RESPONSE; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; EMBRYO; HERPES SIMPLEX VIRUS 1; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; IMMUNOREACTIVITY; MOLECULAR RECOGNITION; MONOCYTE; NONHUMAN; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; PROTEIN TARGETING; SIGNAL TRANSDUCTION; TRANSIENT TRANSFECTION; VIRUS ENTRY; VIRUS ENVELOPE;

ANTIGENS, CD14; CELL LINE; CYTOKINES; HERPESVIRUS 1, HUMAN; HUMANS; IMMUNITY, INNATE; INFLAMMATION MEDIATORS; MONOCYTES; MYELOID DIFFERENTIATION FACTOR 88; NF-KAPPA B; PROTEIN BINDING; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; SOLUBILITY; TNF RECEPTOR-ASSOCIATED FACTOR 6; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 6; VIRAL ENVELOPE PROTEINS;

EID: 84873810684     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0054586     Document Type: Article

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