Occupancy by key transcription factors is a more accurate predictor of enhancer activity than histone modifications or chromatin accessibility

Epigenetics and Chromatin

Volumn 8, Issue 1, 2015, Pages

  Dogan, Nergiz ^a   Wu, Weisheng ^a,b   Morrissey, Christapher S ^a   Chen, Kuan Bei ^a   Stonestrom, Aaron ^c,d   Long, Maria ^a   Keller, Cheryl A ^a   Cheng, Yong ^e   Jain, Deepti ^a   Visel, Axel ^f,g   Pennacchio, Len A ^f,g   Weiss, Mitchell J ^h   Blobel, Gerd A ^c,d   Hardison, Ross C ^a  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

^e STANFORD UNIVERSITY   (United States)

^f LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^g DOE JOINT GENOME INSTITUTE   (United States)

^h ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

Enhancer assay; Functional genomics; GATA1; Gene regulation; Histone modifications; TAL1

Indexed keywords

DEOXYRIBONUCLEASE; E1A ASSOCIATED P300 PROTEIN; SMAD1 PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GATA 1; TRANSCRIPTION FACTOR TAL1;

ANIMAL TISSUE; ARTICLE; BINDING SITE; CELL CULTURE; CHROMATIN; CONTROLLED STUDY; ENHANCER REGION; EPIGENETICS; ERYTHROID CELL; GENE ACTIVATION; GENETIC TRANSFECTION; HISTONE MODIFICATION; METHYLATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING;

MUS MUSCULUS;

EID: 84929320904     PISSN: None     EISSN: 17568935     Source Type: Journal    
DOI: 10.1186/s13072-015-0009-5     Document Type: Article

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