Insm1 cooperates with Neurod1 and Foxa2 to maintain mature pancreatic β-cell function

EMBO Journal

Volumn 34, Issue 10, 2015, Pages 1417-1433

  Jia, Shiqi ^a   Ivanov, Andranik ^a   Blasevic, Dinko ^a   Müller, Thomas ^a   Purfürst, Bettina ^a   Sun, Wei ^a,b   Chen, Wei ^a   Poy, Matthew N ^a   Rajewsky, Nikolaus ^a   Birchmeier, Carmen ^a  

^a MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^b AFFILIATED HOSPITAL OF NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

development; differentiation; Insm1; maturation; metabolisms; pancreatic beta cells

Indexed keywords

HEPATOCYTE NUCLEAR FACTOR 3BETA; INSULINOMA ASSOCIATED 1 TRANSCRIPTION FACTOR; NEUROGENIC DIFFERENTIATION FACTOR; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; DNA BINDING PROTEIN; FOXA2 PROTEIN, MOUSE; INSM1 PROTEIN, MOUSE; NEUROD1 PROTEIN, MOUSE; PROTEIN BINDING;

ADULT; ARTICLE; BINDING SITE; CELL MATURATION; CELL MUTANT; GENE CONTROL; GENE EXPRESSION; GENOME; GLUCOSE METABOLISM; GLUCOSE TRANSPORT; HUMAN; IMMUNOPRECIPITATION; INSULIN RELEASE; MORPHOLOGY; MOUSE; NEWBORN; NONHUMAN; PANCREAS ISLET BETA CELL; PANCREAS ISLET CELL FUNCTION; PRE B LYMPHOCYTE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; WESTERN BLOTTING; ANIMAL; C57BL MOUSE; GENETICS; GENOTYPE; METABOLISM;

MURINAE; MUS;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; DNA-BINDING PROTEINS; GENOTYPE; HEPATOCYTE NUCLEAR FACTOR 3-BETA; INSULIN-SECRETING CELLS; MICE; MICE, INBRED C57BL; PROTEIN BINDING; TRANSCRIPTION FACTORS;

EID: 84929288119     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.15252/embj.201490819     Document Type: Article

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