-
1
-
-
79951648873
-
Pancreas organogenesis: From bud to plexus to gland
-
Pan FC, Wright C. Pancreas organogenesis: from bud to plexus to gland. Dev Dyn 2011;240:530-565
-
(2011)
Dev Dyn
, vol.240
, pp. 530-565
-
-
Pan, F.C.1
Wright, C.2
-
3
-
-
0036777339
-
Signaling and transcriptional control of pancreatic organogenesis
-
Kim SK, MacDonald RJ. Signaling and transcriptional control of pancreatic organogenesis. Curr Opin Genet Dev 2002;12:540-547
-
(2002)
Curr Opin Genet Dev
, vol.12
, pp. 540-547
-
-
Kim, S.K.1
Macdonald, R.J.2
-
5
-
-
84859564568
-
The lessons of early-onset monogenic diabetes for the understanding of diabetes pathogenesis
-
Vaxillaire M, Bonnefond A, Froguel P. The lessons of early-onset monogenic diabetes for the understanding of diabetes pathogenesis. Best Pract Res Clin Endocrinol Metab 2012;26:171-187
-
(2012)
Best Pract Res Clin Endocrinol Metab
, vol.26
, pp. 171-187
-
-
Vaxillaire, M.1
Bonnefond, A.2
Froguel, P.3
-
6
-
-
0142091542
-
Opposing actions of Arx and Pax4 in endocrine pancreas development
-
Collombat P, Mansouri A, Hecksher-Sorensen J, et al. Opposing actions of Arx and Pax4 in endocrine pancreas development. Genes Dev 2003;17:2591- 2603
-
(2003)
Genes Dev
, vol.17
, pp. 2591-2603
-
-
Collombat, P.1
Mansouri, A.2
Hecksher-Sorensen, J.3
-
7
-
-
0347722280
-
The concerted activities of Pax4 and Nkx2.2 are essential to initiate pancreatic beta-cell differentiation
-
Wang J, Elghazi L, Parker SE, et al. The concerted activities of Pax4 and Nkx2.2 are essential to initiate pancreatic beta-cell differentiation. Dev Biol 2004; 266:178-189
-
(2004)
Dev Biol
, vol.266
, pp. 178-189
-
-
Wang, J.1
Elghazi, L.2
Parker, S.E.3
-
8
-
-
38949149704
-
Et al. pdx-1 function is specifically required in embryonic beta cells to generate appropriate numbers of endocrine cell types and maintain glucose homeostasis
-
Gannon M, Ables ET, Crawford L, et al. pdx-1 function is specifically required in embryonic beta cells to generate appropriate numbers of endocrine cell types and maintain glucose homeostasis. Dev Biol 2008;314:406-417
-
(2008)
Dev Biol
, vol.314
, pp. 406-417
-
-
Gannon, M.1
Ables, E.T.2
Crawford, L.3
-
9
-
-
53349178722
-
In vivo reprogramming of adult pancreatic exocrine cells to beta-cells
-
Zhou Q, Brown J, Kanarek A, Rajagopal J, Melton DA. In vivo reprogramming of adult pancreatic exocrine cells to beta-cells. Nature 2008;455:627-632
-
(2008)
Nature
, vol.455
, pp. 627-632
-
-
Zhou, Q.1
Brown, J.2
Kanarek, A.3
Rajagopal, J.4
Melton, D.A.5
-
10
-
-
58049204234
-
Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development
-
Gao N, LeLay J, Vatamaniuk MZ, Rieck S, Friedman JR, Kaestner KH. Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development. Genes Dev 2008;22:3435-3448
-
(2008)
Genes Dev
, vol.22
, pp. 3435-3448
-
-
Gao, N.1
Lelay, J.2
Vatamaniuk, M.Z.3
Rieck, S.4
Friedman, J.R.5
Kaestner, K.H.6
-
11
-
-
84867174750
-
Pancreas-specific deletion of mouse Gata4 and Gata6 causes pancreatic agenesis
-
Xuan S, Borok MJ, Decker KJ, et al. Pancreas-specific deletion of mouse Gata4 and Gata6 causes pancreatic agenesis. J Clin Invest 2012;122:3516-3528
-
(2012)
J Clin Invest
, vol.122
, pp. 3516-3528
-
-
Xuan, S.1
Borok, M.J.2
Decker, K.J.3
-
12
-
-
84867152330
-
GATA4 and GATA6 control mouse pancreas organogenesis
-
Carrasco M, Delgado I, Soria B, Martín F, Rojas A. GATA4 and GATA6 control mouse pancreas organogenesis. J Clin Invest 2012;122:3504-3515
-
(2012)
J Clin Invest
, vol.122
, pp. 3504-3515
-
-
Carrasco, M.1
Delgado, I.2
Soria, B.3
Martín, F.4
Rojas, A.5
-
13
-
-
34447521981
-
+ pancreatic progenitor cells
-
DOI 10.1242/dev.002691
-
Nelson SB, Schaffer AE, Sander M. The transcription factors Nkx6.1 and Nkx6.2 possess equivalent activities in promoting beta-cell fate specification in Pdx1+ pancreatic progenitor cells. Development 2007;134:2491-2500 (Pubitemid 47074143)
-
(2007)
Development
, vol.134
, Issue.13
, pp. 2491-2500
-
-
Nelson, S.B.1
Schaffer, A.E.2
Sander, M.3
-
14
-
-
1842330860
-
Genetic analysis reveals that PAX6 is required for normal transcription of pancreatic hormone genes and islet development
-
Sander M, Neubüser A, Kalamaras J, Ee HC, Martin GR, German MS. Genetic analysis reveals that PAX6 is required for normal transcription of pancreatic hormone genes and islet development. Genes Dev 1997;11:1662-1673 (Pubitemid 27300592)
-
(1997)
Genes and Development
, vol.11
, Issue.13
, pp. 1662-1673
-
-
Sander, M.1
Neubuser, A.2
Kalamaras, J.3
Ee, H.C.4
Martin, G.R.5
German, M.S.6
-
15
-
-
80052381881
-
MafA and MafB activity in pancreatic b cells
-
Hang Y, Stein R. MafA and MafB activity in pancreatic b cells. Trends Endocrinol Metab 2011;22:364-373
-
(2011)
Trends Endocrinol Metab
, vol.22
, pp. 364-373
-
-
Hang, Y.1
Stein, R.2
-
16
-
-
34247183601
-
MafB is required for islet betacell maturation
-
DOI 10.1073/pnas.0700013104
-
Artner I, Blanchi B, Raum JC, et al. MafB is required for islet beta cell maturation. Proc Natl Acad Sci U S A 2007;104:3853-3858 (Pubitemid 47181543)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.10
, pp. 3853-3858
-
-
Artner, I.1
Blanchi, B.2
Raum, J.C.3
Guo, M.4
Kaneko, T.5
Cordes, S.6
Sieweke, M.7
Stein, R.8
-
17
-
-
1542297749
-
The MafA transcription factor appears to be responsible for tissue-specific expression of insulin
-
DOI 10.1073/pnas.0306233101
-
Matsuoka TA, Artner I, Henderson E, Means A, Sander M, Stein R. The MafA transcription factor appears to be responsible for tissue-specific expression of insulin. Proc Natl Acad Sci U S A 2004;101:2930-2933 (Pubitemid 38327713)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.9
, pp. 2930-2933
-
-
Matsuoka, T.-A.1
Artner, I.2
Henderson, E.3
Means, A.4
Sander, M.5
Stein, R.6
-
18
-
-
33646194560
-
A switch from MafB to MafA expression accompanies differentiation to pancreatic beta-cells
-
Nishimura W, Kondo T, Salameh T, et al. A switch from MafB to MafA expression accompanies differentiation to pancreatic beta-cells. Dev Biol 2006; 293:526-539
-
(2006)
Dev Biol
, vol.293
, pp. 526-539
-
-
Nishimura, W.1
Kondo, T.2
Salameh, T.3
-
19
-
-
20344368579
-
MafA is a key regulator of glucose-stimulated insulin secretion
-
DOI 10.1128/MCB.25.12.4969-4976.2005
-
Zhang C, Moriguchi T, Kajihara M, et al. MafA is a key regulator of glucosestimulated insulin secretion. Mol Cell Biol 2005;25:4969-4976 (Pubitemid 40781098)
-
(2005)
Molecular and Cellular Biology
, vol.25
, Issue.12
, pp. 4969-4976
-
-
Zhang, C.1
Moriguchi, T.2
Kajihara, M.3
Esaki, R.4
Harada, A.5
Shimohata, H.6
Oishi, H.7
Hamada, M.8
Morito, N.9
Hasegawa, K.10
Kudo, T.11
Engel, J.D.12
Yamamoto, M.13
Takahashi, S.14
-
20
-
-
77957583357
-
MafA and MafB regulate genes critical to beta-cells in a unique temporal manner
-
Artner I, Hang Y, Mazur M, et al. MafA and MafB regulate genes critical to beta-cells in a unique temporal manner. Diabetes 2010;59:2530-2539
-
(2010)
Diabetes
, vol.59
, pp. 2530-2539
-
-
Artner, I.1
Hang, Y.2
Mazur, M.3
-
21
-
-
84859527233
-
Self-renewing endodermal progenitor lines generated from human pluripotent stem cells
-
Cheng X, Ying L, Lu L, et al. Self-renewing endodermal progenitor lines generated from human pluripotent stem cells. Cell Stem Cell 2012;10:371-384
-
(2012)
Cell Stem Cell
, vol.10
, pp. 371-384
-
-
Cheng, X.1
Ying, L.2
Lu, L.3
-
22
-
-
41849151748
-
Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo
-
DOI 10.1038/nbt1393, PII NBT1393
-
Kroon E, Martinson LA, Kadoya K, et al. Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo. Nat Biotechnol 2008;26:443-452 (Pubitemid 351501814)
-
(2008)
Nature Biotechnology
, vol.26
, Issue.4
, pp. 443-452
-
-
Kroon, E.1
Martinson, L.A.2
Kadoya, K.3
Bang, A.G.4
Kelly, O.G.5
Eliazer, S.6
Young, H.7
Richardson, M.8
Smart, N.G.9
Cunningham, J.10
Agulnick, A.D.11
D'Amour, K.A.12
Carpenter, M.K.13
Baetge, E.E.14
-
23
-
-
69249226366
-
Deletion of the mouse Slc30a8 gene encoding zinc transporter-8 results in impaired insulin secretion
-
Pound LD, Sarkar SA, Benninger RK, et al. Deletion of the mouse Slc30a8 gene encoding zinc transporter-8 results in impaired insulin secretion. Biochem J 2009;421:371-376
-
(2009)
Biochem J
, vol.421
, pp. 371-376
-
-
Pound, L.D.1
Sarkar, S.A.2
Benninger, R.K.3
-
24
-
-
33244458017
-
Critical role of gap junction coupled KATP channel activity for regulated insulin secretion
-
Rocheleau JV, Remedi MS, Granada B, et al. Critical role of gap junction coupled KATP channel activity for regulated insulin secretion. PLoS Biol 2006;4: e26
-
(2006)
PLoS Biol
, vol.4
-
-
Rocheleau, J.V.1
Remedi, M.S.2
Granada, B.3
-
25
-
-
33845540482
-
Pancreatic islet production of vascular endothelial growth factor-A is essential for islet vascularization, revascularization, and function
-
DOI 10.2337/db06-0690
-
Brissova M, Shostak A, Shiota M, et al. Pancreatic islet production of vascular endothelial growth factor - a is essential for islet vascularization, revascularization, and function. Diabetes 2006;55:2974-2985 (Pubitemid 44923633)
-
(2006)
Diabetes
, vol.55
, Issue.11
, pp. 2974-2985
-
-
Brissova, M.1
Shostak, A.2
Shiota, M.3
Wiebe, P.O.4
Poffenberger, G.5
Kantz, J.6
Chen, Z.7
Carr, C.8
Jerome, W.G.9
Chen, J.10
Baldwin, H.S.11
Nicholson, W.12
Bader, D.M.13
Jetton, T.14
Gannon, M.15
Powers, A.C.16
-
26
-
-
84856689283
-
Islet-enriched gene expression and glucose-induced insulin secretion in human and mouse islets
-
Dai C, Brissova M, Hang Y, et al. Islet-enriched gene expression and glucose-induced insulin secretion in human and mouse islets. Diabetologia 2012; 55:707-718
-
(2012)
Diabetologia
, vol.55
, pp. 707-718
-
-
Dai, C.1
Brissova, M.2
Hang, Y.3
-
28
-
-
33751183948
-
In vivo expression and functional characterization of the zinc transporter ZnT8 in glucose-induced insulin secretion
-
Chimienti F, Devergnas S, Pattou F, et al. In vivo expression and functional characterization of the zinc transporter ZnT8 in glucose-induced insulin secretion. J Cell Sci 2006;119:4199-4206
-
(2006)
J Cell Sci
, vol.119
, pp. 4199-4206
-
-
Chimienti, F.1
Devergnas, S.2
Pattou, F.3
-
29
-
-
4344665860
-
Identification and cloning of a beta-cell-specific zinc transporter, ZnT-8, localized into insulin secretory granules
-
DOI 10.2337/diabetes.53.9.2330
-
Chimienti F, Devergnas S, Favier A, Seve M. Identification and cloning of a beta-cell-specific zinc transporter, ZnT-8, localized into insulin secretory granules. Diabetes 2004;53:2330-2337 (Pubitemid 39145586)
-
(2004)
Diabetes
, vol.53
, Issue.9
, pp. 2330-2337
-
-
Chimienti, F.1
Devergnas, S.2
Favier, A.3
Seve, M.4
-
30
-
-
68849091103
-
The diabetes gene Pdx1 regulates the transcriptional network of pancreatic endocrine progenitor cells in mice
-
Oliver-Krasinski JM, Kasner MT, Yang J, et al. The diabetes gene Pdx1 regulates the transcriptional network of pancreatic endocrine progenitor cells in mice. J Clin Invest 2009;119:1888-1898
-
(2009)
J Clin Invest
, vol.119
, pp. 1888-1898
-
-
Oliver-Krasinski, J.M.1
Kasner, M.T.2
Yang, J.3
-
31
-
-
0029868156
-
PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum
-
Offield MF, Jetton TL, Labosky PA, et al. PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum. Development 1996;122: 983-995 (Pubitemid 26096002)
-
(1996)
Development
, vol.122
, Issue.3
, pp. 983-995
-
-
Offield, M.F.1
Jetton, T.L.2
Labosky, P.A.3
Ray, M.4
Stein, R.W.5
Magnuson, M.A.6
Hogan, B.L.M.7
Wright, C.V.E.8
-
32
-
-
33746507174
-
FoxA2, Nkx2.2, and PDX-1 regulate islet beta-cell-specific mafA expression through conserved sequences located between base pairs -8118 and -7750 upstream from the transcription start site
-
Raum JC, Gerrish K, Artner I, et al. FoxA2, Nkx2.2, and PDX-1 regulate islet beta-cell-specific mafA expression through conserved sequences located between base pairs -8118 and -7750 upstream from the transcription start site. Mol Cell Biol 2006;26:5735-5743
-
(2006)
Mol Cell Biol
, vol.26
, pp. 5735-5743
-
-
Raum, J.C.1
Gerrish, K.2
Artner, I.3
-
33
-
-
77956636575
-
Islet beta-cell-specific MafA transcription requires the 59-flanking conserved region 3 control domain
-
Raum JC, Hunter CS, Artner I, et al. Islet beta-cell-specific MafA transcription requires the 59-flanking conserved region 3 control domain. Mol Cell Biol 2010;30:4234-4244
-
(2010)
Mol Cell Biol
, vol.30
, pp. 4234-4244
-
-
Raum, J.C.1
Hunter, C.S.2
Artner, I.3
-
34
-
-
0141765815
-
MafB deficiency causes defective respiratory rhythmogenesis and fatal central apnea at birth
-
Blanchi B, Kelly LM, Viemari JC, et al. MafB deficiency causes defective respiratory rhythmogenesis and fatal central apnea at birth. Nat Neurosci 2003;6: 1091-1100
-
(2003)
Nat Neurosci
, vol.6
, pp. 1091-1100
-
-
Blanchi, B.1
Kelly, L.M.2
Viemari, J.C.3
-
35
-
-
70349280000
-
Insulin crystallization depends on zinc transporter ZnT8 expression, but is not required for normal glucose homeostasis in mice
-
Lemaire K, Ravier MA, Schraenen A, et al. Insulin crystallization depends on zinc transporter ZnT8 expression, but is not required for normal glucose homeostasis in mice. Proc Natl Acad Sci U S A 2009;106:14872-14877
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 14872-14877
-
-
Lemaire, K.1
Ravier, M.A.2
Schraenen, A.3
-
36
-
-
84874638291
-
The role of aging upon b cell turnover
-
Kushner JA. The role of aging upon b cell turnover. J Clin Invest 2013;123: 990-995
-
(2013)
J Clin Invest
, vol.123
, pp. 990-995
-
-
Kushner, J.A.1
-
37
-
-
80052720446
-
Loss of granuphilin and loss of syntaxin-1A cause differential effects on insulin granule docking and fusion
-
Wang H, Ishizaki R, Kobayashi E, Fujiwara T, Akagawa K, Izumi T. Loss of granuphilin and loss of syntaxin-1A cause differential effects on insulin granule docking and fusion. J Biol Chem 2011;286:32244-32250
-
(2011)
J Biol Chem
, vol.286
, pp. 32244-32250
-
-
Wang, H.1
Ishizaki, R.2
Kobayashi, E.3
Fujiwara, T.4
Akagawa, K.5
Izumi, T.6
-
38
-
-
84864390278
-
Munc18-1 regulates first-phase insulin release by promoting granule docking to multiple syntaxin isoforms
-
Oh E, Kalwat MA, Kim MJ, Verhage M, Thurmond DC. Munc18-1 regulates first-phase insulin release by promoting granule docking to multiple syntaxin isoforms. J Biol Chem 2012;287:25821-25833
-
(2012)
J Biol Chem
, vol.287
, pp. 25821-25833
-
-
Oh, E.1
Kalwat, M.A.2
Kim, M.J.3
Verhage, M.4
Thurmond, D.C.5
-
39
-
-
80053408344
-
Mechanisms of control of the free Ca2+ concentration in the endoplasmic reticulum of mouse pancreatic β-cells: Interplay with cell metabolism and [Ca2+]c and role of SERCA2b and SERCA3
-
Ravier MA, Daro D, Roma LP, et al. Mechanisms of control of the free Ca2+ concentration in the endoplasmic reticulum of mouse pancreatic β-cells: interplay with cell metabolism and [Ca2+]c and role of SERCA2b and SERCA3. Diabetes 2011;60:2533-2545
-
(2011)
Diabetes
, vol.60
, pp. 2533-2545
-
-
Ravier, M.A.1
Daro, D.2
Roma, L.P.3
-
40
-
-
35848967815
-
2+ - ATPase 2 expression by prolactin and glucocorticoids is involved in the adaptation of insulin secretory response during the peripartum period
-
DOI 10.1677/JOE-07-0010
-
Anhê GF, Nogueira TC, Nicoletti-Carvalho JE, et al. Signal transducer and activator of transcription 3-regulated sarcoendoplasmic reticulum Ca2+-ATPase 2 expression by prolactin and glucocorticoids is involved in the adaptation of insulin secretory response during the peripartum period. J Endocrinol 2007;195: 17-27 (Pubitemid 350055995)
-
(2007)
Journal of Endocrinology
, vol.195
, Issue.1
, pp. 17-27
-
-
Anhe, G.F.1
Nogueira, T.C.A.2
Nicoletti-Carvalho, J.E.3
Lellis-Santos, C.4
Barbosa, H.C.5
Cipolla-Neto, J.6
Bosqueiro, J.R.7
Boschero, A.C.8
Bordin, S.9
-
41
-
-
44449091627
-
A polymorphism within the G6PC2 gene is associated with fasting plasma glucose levels
-
DOI 10.1126/science.1156849
-
Bouatia-Naji N, Rocheleau G, Van Lommel L, et al. A polymorphism within the G6PC2 gene is associated with fasting plasma glucose levels. Science 2008; 320:1085-1088 (Pubitemid 351929551)
-
(2008)
Science
, vol.320
, Issue.5879
, pp. 1085-1088
-
-
Bouatia-Naji, N.1
Rocheleau, G.2
Van Lommel, L.3
Lemaire, K.4
Schuit, F.5
Cavalcanti-Proenca, C.6
Marchand, M.7
Hartikainen, A.-L.8
Sovio, U.9
De Graeve, F.10
Rung, J.11
Vaxillaire, M.12
Tichet, J.13
Marre, M.14
Balkau, B.15
Weill, J.16
Elliott, P.17
Jarvelin, M.-R.18
Meyre, D.19
Polychronakos, C.20
Dina, C.21
Sladek, R.22
Froguel, P.23
more..
-
42
-
-
79953756654
-
Mafa expression enhances glucose-responsive insulin secretion in neonatal rat beta cells
-
Aguayo-Mazzucato C, Koh A, El Khattabi I, et al. Mafa expression enhances glucose-responsive insulin secretion in neonatal rat beta cells. Diabetologia 2011;54:583-593
-
(2011)
Diabetologia
, vol.54
, pp. 583-593
-
-
Aguayo-Mazzucato, C.1
Koh, A.2
El Khattabi, I.3
-
43
-
-
33750846133
-
Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells
-
DOI 10.1038/nbt1259, PII NBT1259
-
D'Amour KA, Bang AG, Eliazer S, et al. Production of pancreatic hormoneexpressing endocrine cells from human embryonic stem cells. Nat Biotechnol 2006;24:1392-1401 (Pubitemid 44722103)
-
(2006)
Nature Biotechnology
, vol.24
, Issue.11
, pp. 1392-1401
-
-
D'Amour, K.A.1
Bang, A.G.2
Eliazer, S.3
Kelly, O.G.4
Agulnick, A.D.5
Smart, N.G.6
Moorman, M.A.7
Kroon, E.8
Carpenter, M.K.9
Baetge, E.E.10
-
44
-
-
24344459011
-
Assessment of human pancreatic islet architecture and composition by laser scanning confocal microscopy
-
DOI 10.1369/jhc.5C6684.2005
-
Brissova M, Fowler MJ, Nicholson WE, et al. Assessment of human pancreatic islet architecture and composition by laser scanning confocal microscopy. J Histochem Cytochem 2005;53:1087-1097 (Pubitemid 41262977)
-
(2005)
Journal of Histochemistry and Cytochemistry
, vol.53
, Issue.9
, pp. 1087-1097
-
-
Brissova, M.1
Fowler, M.J.2
Nicholson, W.E.3
Chu, A.4
Hirshberg, B.5
Harlan, D.M.6
Powers, A.C.7
-
45
-
-
51349103007
-
MafA is a dedicated activator of the insulin gene in vivo
-
Artner I, Hang Y, Guo M, Gu G, Stein R. MafA is a dedicated activator of the insulin gene in vivo. J Endocrinol 2008;198:271-279
-
(2008)
J Endocrinol
, vol.198
, pp. 271-279
-
-
Artner, I.1
Hang, Y.2
Guo, M.3
Gu, G.4
Stein, R.5
-
46
-
-
77951239859
-
Phosphorylation within the MafA N terminus regulates C-terminal dimerization and DNA binding
-
Guo S, Vanderford NL, Stein R. Phosphorylation within the MafA N terminus regulates C-terminal dimerization and DNA binding. J Biol Chem 2010;285: 12655-12661
-
(2010)
J Biol Chem
, vol.285
, pp. 12655-12661
-
-
Guo, S.1
Vanderford, N.L.2
Stein, R.3
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