Differential transcriptome analysis of diabetes-resistant and -sensitive mouse islets reveals significant overlap with human diabetes susceptibility genes

Diabetes

Volumn 63, Issue 12, 2014, Pages 4230-4238

  Kluth, Oliver ^a,b   Matzke, Daniela ^a,b   Schulze, Gunnar ^a,b   Schwenk, Robert W ^a,b   Joost, Hans Georg ^a,b   Schürmann, Annette ^a  

^a GERMAN INSTITUTE OF HUMAN NUTRITION   (Germany)

^b GERMAN CENTER FOR DIABETES RESEARCH DZD   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 2A; CYCLIN DEPENDENT KINASE INHIBITOR 2B; GLUCOSE; GROWTH FACTOR RECEPTOR BOUND PROTEIN 10; INSULIN; POLYCOMB GROUP PROTEIN; TRANSCRIPTION FACTOR 7 LIKE 2; TRANSCRIPTOME; CELL CYCLE PROTEIN; SOMATOMEDIN BINDING PROTEIN 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CARBOHYDRATE DIET; CELL LOSS; CELL PROLIFERATION; GENE ACTIVATION; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GLUCOSE BLOOD LEVEL; HUMAN; HUMAN CELL; HYPERGLYCEMIA; IMMUNOHISTOCHEMISTRY; INSULIN BLOOD LEVEL; MALE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET CELL; RNA SEQUENCE; SEQUENCE ALIGNMENT; TRANSCRIPTOMICS; VALIDATION PROCESS; ANIMAL; COMPLICATION; GENE EXPRESSION PROFILING; GENETIC PREDISPOSITION; GENETICS; INBRED MOUSE STRAIN; METABOLISM; OBESITY; PANCREAS ISLET; TUMOR SUPPRESSOR GENE;

ANIMALS; CELL CYCLE PROTEINS; CYCLIN-DEPENDENT KINASE INHIBITOR P15; DIABETES MELLITUS, TYPE 2; GENE EXPRESSION PROFILING; GENES, P16; GENETIC PREDISPOSITION TO DISEASE; GRB10 ADAPTOR PROTEIN; HUMANS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 2; ISLETS OF LANGERHANS; MICE; MICE, INBRED STRAINS; OBESITY; TRANSCRIPTION FACTOR 7-LIKE 2 PROTEIN; TRANSCRIPTOME;

EID: 84911895975     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db14-0425     Document Type: Article

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