-
1
-
-
84890472386
-
The Concise Guide to PHARMACOLOGY 2013/14: Enzymes
-
Alexander SPH, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Spedding M, et al. (2013a). The Concise Guide to PHARMACOLOGY 2013/14: Enzymes. Br J Pharmacol 170: 1797-1867.
-
(2013)
Br J Pharmacol
, vol.170
, pp. 1797-1867
-
-
Alexander, S.P.H.1
Benson, H.E.2
Faccenda, E.3
Pawson, A.J.4
Sharman, J.L.5
Spedding, M.6
-
2
-
-
84890450732
-
The Concise Guide to PHARMACOLOGY 2013/14: Transporters
-
Alexander SPH, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Spedding M, et al. (2013b). The Concise Guide to PHARMACOLOGY 2013/14: Transporters. Br J Pharmacol 170: 1706-1796.
-
(2013)
Br J Pharmacol
, vol.170
, pp. 1706-1796
-
-
Alexander, S.P.H.1
Benson, H.E.2
Faccenda, E.3
Pawson, A.J.4
Sharman, J.L.5
Spedding, M.6
-
3
-
-
79959979647
-
Induction of ER stress in response to oxygen-glucose deprivation of cortical cultures involves the activation of the PERK and IRE-1 pathways and of caspase-12
-
Badiola N, Penas C, Minano-Molina A, Barneda-Zahonero B, Fado R, Sanchez-Opazo G, et al. (2011). Induction of ER stress in response to oxygen-glucose deprivation of cortical cultures involves the activation of the PERK and IRE-1 pathways and of caspase-12. Cell Death Dis 2: e149.
-
(2011)
Cell Death Dis
, vol.2
, pp. e149
-
-
Badiola, N.1
Penas, C.2
Minano-Molina, A.3
Barneda-Zahonero, B.4
Fado, R.5
Sanchez-Opazo, G.6
-
4
-
-
34250021865
-
Neuron-specific inactivation of the hypoxia inducible factor 1 alpha increases brain injury in a mouse model of transient focal cerebral ischemia
-
Baranova O, Miranda LF, Pichiule P, Dragatsis I, Johnson RS, Chavez JC, (2007). Neuron-specific inactivation of the hypoxia inducible factor 1 alpha increases brain injury in a mouse model of transient focal cerebral ischemia. J Neurosci 27: 6320-6332.
-
(2007)
J Neurosci
, vol.27
, pp. 6320-6332
-
-
Baranova, O.1
Miranda, L.F.2
Pichiule, P.3
Dragatsis, I.4
Johnson, R.S.5
Chavez, J.C.6
-
5
-
-
84875619809
-
The P-body component USP52/PAN2 is a novel regulator of HIF1A mRNA stability
-
Bett JS, Ibrahim AF, Garg AK, Kelly V, Pedrioli P, Rocha S, et al. (2013). The P-body component USP52/PAN2 is a novel regulator of HIF1A mRNA stability. Biochem J 451: 185-194.
-
(2013)
Biochem J
, vol.451
, pp. 185-194
-
-
Bett, J.S.1
Ibrahim, A.F.2
Garg, A.K.3
Kelly, V.4
Pedrioli, P.5
Rocha, S.6
-
6
-
-
84875320719
-
Neuronal ER stress impedes myeloid-cell-induced vascular regeneration through IRE1alpha degradation of netrin-1
-
Binet F, Mawambo G, Sitaras N, Tetreault N, Lapalme E, Favret S, et al. (2013). Neuronal ER stress impedes myeloid-cell-induced vascular regeneration through IRE1alpha degradation of netrin-1. Cell Metab 17: 353-371.
-
(2013)
Cell Metab
, vol.17
, pp. 353-371
-
-
Binet, F.1
Mawambo, G.2
Sitaras, N.3
Tetreault, N.4
Lapalme, E.5
Favret, S.6
-
7
-
-
33645154135
-
Cellular response to endoplasmic reticulum stress: A matter of life or death
-
Boyce M, Yuan J, (2006). Cellular response to endoplasmic reticulum stress: a matter of life or death. Cell Death Differ 13: 363-373.
-
(2006)
Cell Death Differ
, vol.13
, pp. 363-373
-
-
Boyce, M.1
Yuan, J.2
-
8
-
-
13644256191
-
A selective inhibitor of eIF2α dephosphorylation protects cell from ER stress
-
Boyce M, Bryant KF, Jousse C, Long K, Harding HP, Scheuner D, et al. (2005). A selective inhibitor of eIF2α dephosphorylation protects cell from ER stress. Science 307: 935-939.
-
(2005)
Science
, vol.307
, pp. 935-939
-
-
Boyce, M.1
Bryant, K.F.2
Jousse, C.3
Long, K.4
Harding, H.P.5
Scheuner, D.6
-
9
-
-
48749131140
-
Endoplasmic reticulum Ca2+ dysregulation and endoplasmic reticulum stress following in vitro neuronal ischemia: Role of Na+-K+-Cl- cotransporter
-
Chen X, Kintner DB, Luo J, Baba A, Matsuda T, Sun D, (2008). Endoplasmic reticulum Ca2+ dysregulation and endoplasmic reticulum stress following in vitro neuronal ischemia: role of Na+-K+-Cl- cotransporter. J Neurochem 106: 1563-1576.
-
(2008)
J Neurochem
, vol.106
, pp. 1563-1576
-
-
Chen, X.1
Kintner, D.B.2
Luo, J.3
Baba, A.4
Matsuda, T.5
Sun, D.6
-
10
-
-
78650412221
-
Neuronal apoptosis induced by endoplasmic reticulum stress is regulated by ATF4-CHOP-mediated induction of the Bcl-2 homology 3-only member PUMA
-
Galehdar Z, Swan P, Fuerth B, Callaghan SM, Park DS, Cregan SP, (2010). Neuronal apoptosis induced by endoplasmic reticulum stress is regulated by ATF4-CHOP-mediated induction of the Bcl-2 homology 3-only member PUMA. J Neurosci 30: 16938-16948.
-
(2010)
J Neurosci
, vol.30
, pp. 16938-16948
-
-
Galehdar, Z.1
Swan, P.2
Fuerth, B.3
Callaghan, S.M.4
Park, D.S.5
Cregan, S.P.6
-
11
-
-
84878796836
-
The mechanism of taurine protection against endoplasmic reticulum stress in an animal stroke model of cerebral artery occlusion and stroke-related conditions in primary neuronal cell culture
-
Gharibani PM, Modi J, Pan C, Menzie J, Ma Z, Chen PC, et al. (2013). The mechanism of taurine protection against endoplasmic reticulum stress in an animal stroke model of cerebral artery occlusion and stroke-related conditions in primary neuronal cell culture. Adv Exp Med Biol 776: 241-258.
-
(2013)
Adv Exp Med Biol
, vol.776
, pp. 241-258
-
-
Gharibani, P.M.1
Modi, J.2
Pan, C.3
Menzie, J.4
Ma, Z.5
Chen, P.C.6
-
12
-
-
84862854714
-
Hypoxia-inducible factors and their roles in energy metabolism
-
Goda N, Kanai M, (2012). Hypoxia-inducible factors and their roles in energy metabolism. Int J Hematol 95: 457-463.
-
(2012)
Int J Hematol
, vol.95
, pp. 457-463
-
-
Goda, N.1
Kanai, M.2
-
13
-
-
84867885631
-
Endoplasmic reticulum (ER) stress inhibitor salubrinal protects against ceramide-induced SH-SY5Y cell death
-
Gong T, Wang Q, Lin Z, Chen ML, Sun GZ, (2012). Endoplasmic reticulum (ER) stress inhibitor salubrinal protects against ceramide-induced SH-SY5Y cell death. Biochem Biophys Res Commun 427: 461-465.
-
(2012)
Biochem Biophys Res Commun
, vol.427
, pp. 461-465
-
-
Gong, T.1
Wang, Q.2
Lin, Z.3
Chen, M.L.4
Sun, G.Z.5
-
14
-
-
44649199238
-
Loss of c/EBP-beta activity promotes the adaptive to apoptotic switch in hypoxic cortical neurons
-
Halterman MW, De JC, Rempe DA, Schor NF, Federoff HJ, (2008). Loss of c/EBP-beta activity promotes the adaptive to apoptotic switch in hypoxic cortical neurons. Mol Cell Neurosci 38: 125-137.
-
(2008)
Mol Cell Neurosci
, vol.38
, pp. 125-137
-
-
Halterman, M.W.1
De, J.C.2
Rempe, D.A.3
Schor, N.F.4
Federoff, H.J.5
-
15
-
-
77954377779
-
The endoplasmic reticulum stress response factor CHOP-10 protects against hypoxia-induced neuronal death
-
Halterman MW, Gill M, DeJesus C, Ogihara M, Schor NF, Federoff HJ, (2010). The endoplasmic reticulum stress response factor CHOP-10 protects against hypoxia-induced neuronal death. J Biol Chem 285: 21329-21340.
-
(2010)
J Biol Chem
, vol.285
, pp. 21329-21340
-
-
Halterman, M.W.1
Gill, M.2
Dejesus, C.3
Ogihara, M.4
Schor, N.F.5
Federoff, H.J.6
-
16
-
-
75649142054
-
A unique modulator of endoplasmic reticulum stress-signalling pathways: The novel pharmacological properties of amiloride in glial cells
-
Hosoi T, Kume A, Otani K, Oba T, Ozawa K, (2010). A unique modulator of endoplasmic reticulum stress-signalling pathways: the novel pharmacological properties of amiloride in glial cells. Br J Pharmacol 159: 428-437.
-
(2010)
Br J Pharmacol
, vol.159
, pp. 428-437
-
-
Hosoi, T.1
Kume, A.2
Otani, K.3
Oba, T.4
Ozawa, K.5
-
17
-
-
0035917808
-
Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation
-
Jaakkola P, Mole DR, Tian YM, Wilson MI, Gielbert J, Gaskell SJ, et al. (2001). Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation. Science 292: 468-472.
-
(2001)
Science
, vol.292
, pp. 468-472
-
-
Jaakkola, P.1
Mole, D.R.2
Tian, Y.M.3
Wilson, M.I.4
Gielbert, J.5
Gaskell, S.J.6
-
18
-
-
84884725230
-
The role of HIF in cobalt-induced ischemic tolerance
-
Jones SM, Novak AE, Elliott JP, (2013). The role of HIF in cobalt-induced ischemic tolerance. Neuroscience 252: 420-430.
-
(2013)
Neuroscience
, vol.252
, pp. 420-430
-
-
Jones, S.M.1
Novak, A.E.2
Elliott, J.P.3
-
19
-
-
0033859860
-
Veratridine induces apoptotic death in bovine chromaffin cells through superoxide production
-
Jordan J, Galindo MF, Calvo S, Gonzalez-Garcia C, Cena V, (2000). Veratridine induces apoptotic death in bovine chromaffin cells through superoxide production. Br J Pharmacol 130: 1496-1504.
-
(2000)
Br J Pharmacol
, vol.130
, pp. 1496-1504
-
-
Jordan, J.1
Galindo, M.F.2
Calvo, S.3
Gonzalez-Garcia, C.4
Cena, V.5
-
20
-
-
77954326944
-
Animal research: Reporting in vivo experiments: The ARRIVE guidelines
-
Kilkenny C, Browne W, Cuthill IC, Emerson M, Altman DG, (2010). Animal research: reporting in vivo experiments: the ARRIVE guidelines. Br J Pharmacol 160: 1577-1579.
-
(2010)
Br J Pharmacol
, vol.160
, pp. 1577-1579
-
-
Kilkenny, C.1
Browne, W.2
Cuthill, I.C.3
Emerson, M.4
Altman, D.G.5
-
21
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
-
Livak KJ, Schmittgen TD, (2001). Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25: 402-408.
-
(2001)
Methods
, vol.25
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
22
-
-
32444433450
-
Hypoxia-induced energy stress regulates mRNA translation and cell growth
-
Liu L, Cash TP, Jones RG, Keith B, Thompson CB, Simon MC, (2006). Hypoxia-induced energy stress regulates mRNA translation and cell growth. Mol Cell 21: 521-531.
-
(2006)
Mol Cell
, vol.21
, pp. 521-531
-
-
Liu, L.1
Cash, T.P.2
Jones, R.G.3
Keith, B.4
Thompson, C.B.5
Simon, M.C.6
-
23
-
-
84856209830
-
HIF-1alpha is neuroprotective during the early phases of mild hypoxia in rat cortical neurons
-
Lopez-Hernandez B, Posadas I, Podlesniy P, Abad MA, Trullas R, Ceña V, (2012). HIF-1alpha is neuroprotective during the early phases of mild hypoxia in rat cortical neurons. Exp Neurol 233: 543-554.
-
(2012)
Exp Neurol
, vol.233
, pp. 543-554
-
-
Lopez-Hernandez, B.1
Posadas, I.2
Podlesniy, P.3
Abad, M.A.4
Trullas, R.5
Ceña, V.6
-
24
-
-
77950473770
-
Hsp70 and CHIP selectively mediate ubiquitination and degradation of hypoxia-inducible factor (HIF)-1alpha but Not HIF-2alpha
-
Luo W, Zhong J, Chang R, Hu H, Pandey A, Semenza GL, (2010). Hsp70 and CHIP selectively mediate ubiquitination and degradation of hypoxia-inducible factor (HIF)-1alpha but Not HIF-2alpha. J Biol Chem 285: 3651-3663.
-
(2010)
J Biol Chem
, vol.285
, pp. 3651-3663
-
-
Luo, W.1
Zhong, J.2
Chang, R.3
Hu, H.4
Pandey, A.5
Semenza, G.L.6
-
25
-
-
77954331629
-
Guidelines for reporting experiments involving animals: The ARRIVE guidelines
-
McGrath JC, Drummond GB, McLachlan EM, Kilkenny C, Wainwright CL, (2010). Guidelines for reporting experiments involving animals: the ARRIVE guidelines. Br J Pharmacol 160: 1573-1576.
-
(2010)
Br J Pharmacol
, vol.160
, pp. 1573-1576
-
-
McGrath, J.C.1
Drummond, G.B.2
McLachlan, E.M.3
Kilkenny, C.4
Wainwright, C.L.5
-
26
-
-
58049194159
-
Hypoxia-inducible factor 1 alpha under rapid enzymatic hypoxia: Cells sense decrements of oxygen but not hypoxia per se
-
Millonig G, Hegedusch S, Becker L, Seitz HK, Schuppan D, Mueller S, (2009). Hypoxia-inducible factor 1 alpha under rapid enzymatic hypoxia: cells sense decrements of oxygen but not hypoxia per se. Free Radic Biol Med 46: 182-191.
-
(2009)
Free Radic Biol Med
, vol.46
, pp. 182-191
-
-
Millonig, G.1
Hegedusch, S.2
Becker, L.3
Seitz, H.K.4
Schuppan, D.5
Mueller, S.6
-
27
-
-
0037072937
-
An endoplasmic reticulum stress-specific caspase cascade in apoptosis. Cytochrome c-independent activation of caspase-9 by caspase-12
-
Morishima N, Nakanishi K, Takenouchi H, Shibata T, Yasuhiko Y, (2002). An endoplasmic reticulum stress-specific caspase cascade in apoptosis. Cytochrome c-independent activation of caspase-9 by caspase-12. J Biol Chem 277: 34287-34294.
-
(2002)
J Biol Chem
, vol.277
, pp. 34287-34294
-
-
Morishima, N.1
Nakanishi, K.2
Takenouchi, H.3
Shibata, T.4
Yasuhiko, Y.5
-
28
-
-
0034698878
-
Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis
-
Nakagawa T, Yuan J, (2000). Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis. J Cell Biol 150: 887-894.
-
(2000)
J Cell Biol
, vol.150
, pp. 887-894
-
-
Nakagawa, T.1
Yuan, J.2
-
29
-
-
84879368095
-
Restoring endoplasmic reticulum homeostasis improves functional recovery after spinal cord injury
-
Ohri SS, Hetman M, Whittemore SR, (2013). Restoring endoplasmic reticulum homeostasis improves functional recovery after spinal cord injury. Neurobiol Dis 58: 29-37.
-
(2013)
Neurobiol Dis
, vol.58
, pp. 29-37
-
-
Ohri, S.S.1
Hetman, M.2
Whittemore, S.R.3
-
30
-
-
79251600505
-
Overexpressing GRP78 influences Ca2+ handling and function of mitochondria in astrocytes after ischemia-like stress
-
Ouyang YB, Xu LJ, Emery JF, Lee AS, Giffard RG, (2011). Overexpressing GRP78 influences Ca2+ handling and function of mitochondria in astrocytes after ischemia-like stress. Mitochondrion 11: 279-286.
-
(2011)
Mitochondrion
, vol.11
, pp. 279-286
-
-
Ouyang, Y.B.1
Xu, L.J.2
Emery, J.F.3
Lee, A.S.4
Giffard, R.G.5
-
31
-
-
84864752911
-
Beneficial effect of taurine on hypoxia- and glutamate-induced endoplasmic reticulum stress pathways in primary neuronal culture
-
Pan C, Prentice H, Price AL, Wu JY, (2012). Beneficial effect of taurine on hypoxia- and glutamate-induced endoplasmic reticulum stress pathways in primary neuronal culture. Amino Acids 43: 845-855.
-
(2012)
Amino Acids
, vol.43
, pp. 845-855
-
-
Pan, C.1
Prentice, H.2
Price, A.L.3
Wu, J.Y.4
-
32
-
-
84891791940
-
The IUPHAR/BPS Guide to PHARMACOLOGY: An expert-driven knowledge base of drug targets and their ligands
-
NC-IUPHAR
-
Pawson AJ, Sharman JL, Benson HE, Faccenda E, Alexander SP, Buneman OP, et al.; NC-IUPHAR (2014). The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledge base of drug targets and their ligands. Nucl Acids Res 42 (Database Issue): D1098-D1106.
-
(2014)
Nucl Acids Res
, vol.42
, Issue.DATABASE ISSUE
, pp. D1098-D1106
-
-
Pawson, A.J.1
Sharman, J.L.2
Benson, H.E.3
Faccenda, E.4
Alexander, S.P.5
Buneman, O.P.6
-
33
-
-
84155164308
-
Dendrimer-mediated siRNA delivery knocks down Beclin 1 and potentiates NMDA-mediated toxicity in rat cortical neurons
-
Perez-Carrion MD, Perez-Martinez FC, Merino S, Sanchez-Verdu P, Martinez-Hernandez J, Lujan R, et al. (2012). Dendrimer-mediated siRNA delivery knocks down Beclin 1 and potentiates NMDA-mediated toxicity in rat cortical neurons. J Neurochem 120: 259-268.
-
(2012)
J Neurochem
, vol.120
, pp. 259-268
-
-
Perez-Carrion, M.D.1
Perez-Martinez, F.C.2
Merino, S.3
Sanchez-Verdu, P.4
Martinez-Hernandez, J.5
Lujan, R.6
-
34
-
-
84865540583
-
Enhanced docetaxel-mediated cytotoxicity in human prostate cancer cells through knockdown of cofilin-1 by carbon nanohorn delivered siRNA
-
Perez-Martinez FC, Carrion B, Lucio MI, Rubio N, Herrero MA, Vazquez E, et al. (2012). Enhanced docetaxel-mediated cytotoxicity in human prostate cancer cells through knockdown of cofilin-1 by carbon nanohorn delivered siRNA. Biomaterials 33: 8152-8159.
-
(2012)
Biomaterials
, vol.33
, pp. 8152-8159
-
-
Perez-Martinez, F.C.1
Carrion, B.2
Lucio, M.I.3
Rubio, N.4
Herrero, M.A.5
Vazquez, E.6
-
35
-
-
33847624535
-
Acetaminophen potentiates staurosporine-induced death in a human neuroblastoma cell line
-
Posadas I, Vellecco V, Santos P, Prieto-Lloret J, Ceña V, (2007). Acetaminophen potentiates staurosporine-induced death in a human neuroblastoma cell line. Br J Pharmacol 150: 577-585.
-
(2007)
Br J Pharmacol
, vol.150
, pp. 577-585
-
-
Posadas, I.1
Vellecco, V.2
Santos, P.3
Prieto-Lloret, J.4
Ceña, V.5
-
36
-
-
63949086284
-
Highly efficient transfection of rat cortical neurons using carbosilane dendrimers unveils a neuroprotective role for HIF-1alpha in early chemical hypoxia-mediated neurotoxicity
-
Posadas I, Lopez-Hernandez B, Clemente MI, Jimenez JL, Ortega P, de la Mata J, et al. (2009). Highly efficient transfection of rat cortical neurons using carbosilane dendrimers unveils a neuroprotective role for HIF-1alpha in early chemical hypoxia-mediated neurotoxicity. Pharm Res 26: 1181-1191.
-
(2009)
Pharm Res
, vol.26
, pp. 1181-1191
-
-
Posadas, I.1
Lopez-Hernandez, B.2
Clemente, M.I.3
Jimenez, J.L.4
Ortega, P.5
De La Mata, J.6
-
37
-
-
78650729340
-
Acetaminophen induces apoptosis in rat cortical neurons
-
Posadas I, Santos P, Blanco A, Munoz-Fernandez M, Ceña V, (2010). Acetaminophen induces apoptosis in rat cortical neurons. PLoS ONE 5: e15360.
-
(2010)
PLoS ONE
, vol.5
, pp. e15360
-
-
Posadas, I.1
Santos, P.2
Blanco, A.3
Munoz-Fernandez, M.4
Ceña, V.5
-
38
-
-
84855932980
-
Cofilin activation mediates Bax translocation to mitochondria during excitotoxic neuronal death
-
Posadas I, Perez-Martinez FC, Guerra J, Sanchez-Verdu P, Ceña V, (2012). Cofilin activation mediates Bax translocation to mitochondria during excitotoxic neuronal death. J Neurochem 120: 515-527.
-
(2012)
J Neurochem
, vol.120
, pp. 515-527
-
-
Posadas, I.1
Perez-Martinez, F.C.2
Guerra, J.3
Sanchez-Verdu, P.4
Ceña, V.5
-
39
-
-
0037077254
-
Coupling endoplasmic reticulum stress to the cell death program. An Apaf-1-independent intrinsic pathway
-
Rao RV, Castro-Obregon S, Frankowski H, Schuler M, Stoka V, del Rio G, et al. (2002). Coupling endoplasmic reticulum stress to the cell death program. An Apaf-1-independent intrinsic pathway. J Biol Chem 277: 21836-21842.
-
(2002)
J Biol Chem
, vol.277
, pp. 21836-21842
-
-
Rao, R.V.1
Castro-Obregon, S.2
Frankowski, H.3
Schuler, M.4
Stoka, V.5
Del Rio, G.6
-
40
-
-
36849087900
-
Harnessing hypoxic adaptation to prevent, treat, and repair stroke
-
Ratan RR, Siddiq A, Smirnova N, Karpisheva K, Haskew-Layton R, McConoughey S, et al. (2007). Harnessing hypoxic adaptation to prevent, treat, and repair stroke. J Mol Med (Berl) 85: 1331-1338.
-
(2007)
J Mol Med (Berl)
, vol.85
, pp. 1331-1338
-
-
Ratan, R.R.1
Siddiq, A.2
Smirnova, N.3
Karpisheva, K.4
Haskew-Layton, R.5
McConoughey, S.6
-
41
-
-
0032053169
-
Oxygen sensing, hypoxia-inducible factor-1 and the regulation of mammalian gene expression
-
Ratcliffe PJ, O'Rourke JF, Maxwell PH, Pugh CW, (1998). Oxygen sensing, hypoxia-inducible factor-1 and the regulation of mammalian gene expression. J Exp Biol 201: 1153-1162.
-
(1998)
J Exp Biol
, vol.201
, pp. 1153-1162
-
-
Ratcliffe, P.J.1
O'Rourke, J.F.2
Maxwell, P.H.3
Pugh, C.W.4
-
42
-
-
84870838478
-
Endoplasmic reticulum dysfunction in neurological disease
-
Roussel BD, Kruppa AJ, Miranda E, Crowther DC, Lomas DA, Marciniak SJ, (2013). Endoplasmic reticulum dysfunction in neurological disease. Lancet Neurol 12: 105-118.
-
(2013)
Lancet Neurol
, vol.12
, pp. 105-118
-
-
Roussel, B.D.1
Kruppa, A.J.2
Miranda, E.3
Crowther, D.C.4
Lomas, D.A.5
Marciniak, S.J.6
-
43
-
-
0032566706
-
Induction of hypoxia inducible factor 1 by oxygen glucose deprivation is attenuated by hypoxic preconditioning in rat cultured neurons
-
Ruscher K, Isaev N, Trendelenburg G, Weih M, Iurato L, Meisel A, et al. (1998). Induction of hypoxia inducible factor 1 by oxygen glucose deprivation is attenuated by hypoxic preconditioning in rat cultured neurons. Neurosci Lett 254: 117-120.
-
(1998)
Neurosci Lett
, vol.254
, pp. 117-120
-
-
Ruscher, K.1
Isaev, N.2
Trendelenburg, G.3
Weih, M.4
Iurato, L.5
Meisel, A.6
-
44
-
-
0034006016
-
HIF-1: Mediator of physiological and pathophysiological responses to hypoxia
-
Semenza GL, (2000). HIF-1: mediator of physiological and pathophysiological responses to hypoxia. J Appl Physiol 88: 1474-1480.
-
(2000)
J Appl Physiol
, vol.88
, pp. 1474-1480
-
-
Semenza, G.L.1
-
45
-
-
56149089262
-
Hypoxia-inducible factor 1 and cancer pathogenesis
-
Semenza GL, (2008). Hypoxia-inducible factor 1 and cancer pathogenesis. IUBMB Life 60: 591-597.
-
(2008)
IUBMB Life
, vol.60
, pp. 591-597
-
-
Semenza, G.L.1
-
46
-
-
84895075249
-
Orexins protect neuronal cell cultures against hypoxic stress: An involvement of Akt signaling
-
Sokolowska P, Urbanska A, Bieganska K, Wagner W, Ciszewski W, Namiecinska M, et al. (2014). Orexins protect neuronal cell cultures against hypoxic stress: an involvement of Akt signaling. J Mol Neurosci 52: 48-55.
-
(2014)
J Mol Neurosci
, vol.52
, pp. 48-55
-
-
Sokolowska, P.1
Urbanska, A.2
Bieganska, K.3
Wagner, W.4
Ciszewski, W.5
Namiecinska, M.6
-
47
-
-
0036063247
-
BiP binding keeps ATF6 at bay
-
Sommer T, Jarosch E, (2002). BiP binding keeps ATF6 at bay. Dev Cell 3: 1-2.
-
(2002)
Dev Cell
, vol.3
, pp. 1-2
-
-
Sommer, T.1
Jarosch, E.2
-
48
-
-
84859435142
-
The role of ER stress-induced apoptosis in neurodegeneration
-
Stefani IC, Wright D, Polizzi KM, Kontoravdi C, (2012). The role of ER stress-induced apoptosis in neurodegeneration. Curr Alzheimer Res 9: 373-387.
-
(2012)
Curr Alzheimer Res
, vol.9
, pp. 373-387
-
-
Stefani, I.C.1
Wright, D.2
Polizzi, K.M.3
Kontoravdi, C.4
-
49
-
-
1342305497
-
Caspase-12 and ER-stress-mediated apoptosis: The story so far
-
Szegezdi E, Fitzgerald U, Samali A, (2003). Caspase-12 and ER-stress-mediated apoptosis: the story so far. Ann N Y Acad Sci 1010: 186-194.
-
(2003)
Ann N y Acad Sci
, vol.1010
, pp. 186-194
-
-
Szegezdi, E.1
Fitzgerald, U.2
Samali, A.3
-
50
-
-
79957936182
-
Bcl-x(L) blocks a mitochondrial inner membrane channel and prevents Ca2+ overload-mediated cell death
-
Tornero D, Posadas I, Ceña V, (2011). Bcl-x(L) blocks a mitochondrial inner membrane channel and prevents Ca2+ overload-mediated cell death. PLoS ONE 6: e20423.
-
(2011)
PLoS ONE
, vol.6
, pp. e20423
-
-
Tornero, D.1
Posadas, I.2
Ceña, V.3
-
51
-
-
33749262336
-
Cobalt induces hypoxia-inducible factor-1alpha (HIF-1alpha) in HeLa cells by an iron-independent, but ROS-, PI-3K- and MAPK-dependent mechanism
-
Triantafyllou A, Liakos P, Tsakalof A, Georgatsou E, Simos G, Bonanou S, (2006). Cobalt induces hypoxia-inducible factor-1alpha (HIF-1alpha) in HeLa cells by an iron-independent, but ROS-, PI-3K- and MAPK-dependent mechanism. Free Radic Res 40: 847-856.
-
(2006)
Free Radic Res
, vol.40
, pp. 847-856
-
-
Triantafyllou, A.1
Liakos, P.2
Tsakalof, A.3
Georgatsou, E.4
Simos, G.5
Bonanou, S.6
-
52
-
-
2442544693
-
Prolonged hypoxia differentially regulates hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha expression in lung epithelial cells: Implication of natural antisense HIF-1alpha
-
Uchida T, Rossignol F, Matthay MA, Mounier R, Couette S, Clottes E, et al. (2004). Prolonged hypoxia differentially regulates hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha expression in lung epithelial cells: implication of natural antisense HIF-1alpha. J Biol Chem 279: 14871-14878.
-
(2004)
J Biol Chem
, vol.279
, pp. 14871-14878
-
-
Uchida, T.1
Rossignol, F.2
Matthay, M.A.3
Mounier, R.4
Couette, S.5
Clottes, E.6
-
53
-
-
84861652703
-
The central role of initiator caspase-9 in apoptosis signal transduction and the regulation of its activation and activity on the apoptosome
-
Wurstle ML, Laussmann MA, Rehm M, (2012). The central role of initiator caspase-9 in apoptosis signal transduction and the regulation of its activation and activity on the apoptosome. Exp Cell Res 318: 1213-1220.
-
(2012)
Exp Cell Res
, vol.318
, pp. 1213-1220
-
-
Wurstle, M.L.1
Laussmann, M.A.2
Rehm, M.3
-
54
-
-
26444442450
-
Endoplasmic reticulum stress: Cell life and death decisions
-
Xu C, Bailly-Maitre B, Reed JC, (2005). Endoplasmic reticulum stress: cell life and death decisions. J Clin Invest 115: 2656-2664.
-
(2005)
J Clin Invest
, vol.115
, pp. 2656-2664
-
-
Xu, C.1
Bailly-Maitre, B.2
Reed, J.C.3
-
55
-
-
0037844847
-
Cobalt inhibits the interaction between hypoxia-inducible factor-alpha and von Hippel-Lindau protein by direct binding to hypoxia-inducible factor-alpha
-
Yuan Y, Hilliard G, Ferguson T, Millhorn DE, (2003). Cobalt inhibits the interaction between hypoxia-inducible factor-alpha and von Hippel-Lindau protein by direct binding to hypoxia-inducible factor-alpha. J Biol Chem 278: 15911-15916.
-
(2003)
J Biol Chem
, vol.278
, pp. 15911-15916
-
-
Yuan, Y.1
Hilliard, G.2
Ferguson, T.3
Millhorn, D.E.4
-
56
-
-
34247614521
-
HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity
-
Zhang H, Gao P, Fukuda R, Kumar G, Krishnamachary B, Zeller KI, et al. (2007). HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity. Cancer Cell 11: 407-420.
-
(2007)
Cancer Cell
, vol.11
, pp. 407-420
-
-
Zhang, H.1
Gao, P.2
Fukuda, R.3
Kumar, G.4
Krishnamachary, B.5
Zeller, K.I.6
-
57
-
-
0033596980
-
An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9
-
Zou H, Li Y, Liu X, Wang X, (1999). An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9. J Biol Chem 274: 11549-11556.
-
(1999)
J Biol Chem
, vol.274
, pp. 11549-11556
-
-
Zou, H.1
Li, Y.2
Liu, X.3
Wang, X.4
|