메뉴 건너뛰기




Volumn 172, Issue 11, 2015, Pages 2838-2851

The endoplasmic reticulum stress and the HIF-1 signalling pathways are involved in the neuronal damage caused by chemical hypoxia

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; CASPASE 12; CASPASE 3; CASPASE 9; COBALT CHLORIDE; GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; HYPOXIA INDUCIBLE FACTOR 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INITIATION FACTOR 2ALPHA; MESSENGER RNA; PRK LIKE ENDOPLASMIC RETICULUM KINASE; PROTEIN KINASE; UNCLASSIFIED DRUG; CASP12 PROTEIN, RAT; CINNAMIC ACID DERIVATIVE; COBALT; DDIT3 PROTEIN, RAT; HIF1A PROTEIN, RAT; INITIATION FACTOR 2; PERK KINASE; PROTEIN KINASE R; SALUBRINAL; THIOUREA;

EID: 84929207226     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/bph.13095     Document Type: Article
Times cited : (45)

References (57)
  • 3
    • 79959979647 scopus 로고    scopus 로고
    • Induction of ER stress in response to oxygen-glucose deprivation of cortical cultures involves the activation of the PERK and IRE-1 pathways and of caspase-12
    • Badiola N, Penas C, Minano-Molina A, Barneda-Zahonero B, Fado R, Sanchez-Opazo G, et al. (2011). Induction of ER stress in response to oxygen-glucose deprivation of cortical cultures involves the activation of the PERK and IRE-1 pathways and of caspase-12. Cell Death Dis 2: e149.
    • (2011) Cell Death Dis , vol.2 , pp. e149
    • Badiola, N.1    Penas, C.2    Minano-Molina, A.3    Barneda-Zahonero, B.4    Fado, R.5    Sanchez-Opazo, G.6
  • 4
    • 34250021865 scopus 로고    scopus 로고
    • Neuron-specific inactivation of the hypoxia inducible factor 1 alpha increases brain injury in a mouse model of transient focal cerebral ischemia
    • Baranova O, Miranda LF, Pichiule P, Dragatsis I, Johnson RS, Chavez JC, (2007). Neuron-specific inactivation of the hypoxia inducible factor 1 alpha increases brain injury in a mouse model of transient focal cerebral ischemia. J Neurosci 27: 6320-6332.
    • (2007) J Neurosci , vol.27 , pp. 6320-6332
    • Baranova, O.1    Miranda, L.F.2    Pichiule, P.3    Dragatsis, I.4    Johnson, R.S.5    Chavez, J.C.6
  • 5
    • 84875619809 scopus 로고    scopus 로고
    • The P-body component USP52/PAN2 is a novel regulator of HIF1A mRNA stability
    • Bett JS, Ibrahim AF, Garg AK, Kelly V, Pedrioli P, Rocha S, et al. (2013). The P-body component USP52/PAN2 is a novel regulator of HIF1A mRNA stability. Biochem J 451: 185-194.
    • (2013) Biochem J , vol.451 , pp. 185-194
    • Bett, J.S.1    Ibrahim, A.F.2    Garg, A.K.3    Kelly, V.4    Pedrioli, P.5    Rocha, S.6
  • 6
    • 84875320719 scopus 로고    scopus 로고
    • Neuronal ER stress impedes myeloid-cell-induced vascular regeneration through IRE1alpha degradation of netrin-1
    • Binet F, Mawambo G, Sitaras N, Tetreault N, Lapalme E, Favret S, et al. (2013). Neuronal ER stress impedes myeloid-cell-induced vascular regeneration through IRE1alpha degradation of netrin-1. Cell Metab 17: 353-371.
    • (2013) Cell Metab , vol.17 , pp. 353-371
    • Binet, F.1    Mawambo, G.2    Sitaras, N.3    Tetreault, N.4    Lapalme, E.5    Favret, S.6
  • 7
    • 33645154135 scopus 로고    scopus 로고
    • Cellular response to endoplasmic reticulum stress: A matter of life or death
    • Boyce M, Yuan J, (2006). Cellular response to endoplasmic reticulum stress: a matter of life or death. Cell Death Differ 13: 363-373.
    • (2006) Cell Death Differ , vol.13 , pp. 363-373
    • Boyce, M.1    Yuan, J.2
  • 8
    • 13644256191 scopus 로고    scopus 로고
    • A selective inhibitor of eIF2α dephosphorylation protects cell from ER stress
    • Boyce M, Bryant KF, Jousse C, Long K, Harding HP, Scheuner D, et al. (2005). A selective inhibitor of eIF2α dephosphorylation protects cell from ER stress. Science 307: 935-939.
    • (2005) Science , vol.307 , pp. 935-939
    • Boyce, M.1    Bryant, K.F.2    Jousse, C.3    Long, K.4    Harding, H.P.5    Scheuner, D.6
  • 9
    • 48749131140 scopus 로고    scopus 로고
    • Endoplasmic reticulum Ca2+ dysregulation and endoplasmic reticulum stress following in vitro neuronal ischemia: Role of Na+-K+-Cl- cotransporter
    • Chen X, Kintner DB, Luo J, Baba A, Matsuda T, Sun D, (2008). Endoplasmic reticulum Ca2+ dysregulation and endoplasmic reticulum stress following in vitro neuronal ischemia: role of Na+-K+-Cl- cotransporter. J Neurochem 106: 1563-1576.
    • (2008) J Neurochem , vol.106 , pp. 1563-1576
    • Chen, X.1    Kintner, D.B.2    Luo, J.3    Baba, A.4    Matsuda, T.5    Sun, D.6
  • 10
    • 78650412221 scopus 로고    scopus 로고
    • Neuronal apoptosis induced by endoplasmic reticulum stress is regulated by ATF4-CHOP-mediated induction of the Bcl-2 homology 3-only member PUMA
    • Galehdar Z, Swan P, Fuerth B, Callaghan SM, Park DS, Cregan SP, (2010). Neuronal apoptosis induced by endoplasmic reticulum stress is regulated by ATF4-CHOP-mediated induction of the Bcl-2 homology 3-only member PUMA. J Neurosci 30: 16938-16948.
    • (2010) J Neurosci , vol.30 , pp. 16938-16948
    • Galehdar, Z.1    Swan, P.2    Fuerth, B.3    Callaghan, S.M.4    Park, D.S.5    Cregan, S.P.6
  • 11
    • 84878796836 scopus 로고    scopus 로고
    • The mechanism of taurine protection against endoplasmic reticulum stress in an animal stroke model of cerebral artery occlusion and stroke-related conditions in primary neuronal cell culture
    • Gharibani PM, Modi J, Pan C, Menzie J, Ma Z, Chen PC, et al. (2013). The mechanism of taurine protection against endoplasmic reticulum stress in an animal stroke model of cerebral artery occlusion and stroke-related conditions in primary neuronal cell culture. Adv Exp Med Biol 776: 241-258.
    • (2013) Adv Exp Med Biol , vol.776 , pp. 241-258
    • Gharibani, P.M.1    Modi, J.2    Pan, C.3    Menzie, J.4    Ma, Z.5    Chen, P.C.6
  • 12
    • 84862854714 scopus 로고    scopus 로고
    • Hypoxia-inducible factors and their roles in energy metabolism
    • Goda N, Kanai M, (2012). Hypoxia-inducible factors and their roles in energy metabolism. Int J Hematol 95: 457-463.
    • (2012) Int J Hematol , vol.95 , pp. 457-463
    • Goda, N.1    Kanai, M.2
  • 13
    • 84867885631 scopus 로고    scopus 로고
    • Endoplasmic reticulum (ER) stress inhibitor salubrinal protects against ceramide-induced SH-SY5Y cell death
    • Gong T, Wang Q, Lin Z, Chen ML, Sun GZ, (2012). Endoplasmic reticulum (ER) stress inhibitor salubrinal protects against ceramide-induced SH-SY5Y cell death. Biochem Biophys Res Commun 427: 461-465.
    • (2012) Biochem Biophys Res Commun , vol.427 , pp. 461-465
    • Gong, T.1    Wang, Q.2    Lin, Z.3    Chen, M.L.4    Sun, G.Z.5
  • 14
    • 44649199238 scopus 로고    scopus 로고
    • Loss of c/EBP-beta activity promotes the adaptive to apoptotic switch in hypoxic cortical neurons
    • Halterman MW, De JC, Rempe DA, Schor NF, Federoff HJ, (2008). Loss of c/EBP-beta activity promotes the adaptive to apoptotic switch in hypoxic cortical neurons. Mol Cell Neurosci 38: 125-137.
    • (2008) Mol Cell Neurosci , vol.38 , pp. 125-137
    • Halterman, M.W.1    De, J.C.2    Rempe, D.A.3    Schor, N.F.4    Federoff, H.J.5
  • 15
    • 77954377779 scopus 로고    scopus 로고
    • The endoplasmic reticulum stress response factor CHOP-10 protects against hypoxia-induced neuronal death
    • Halterman MW, Gill M, DeJesus C, Ogihara M, Schor NF, Federoff HJ, (2010). The endoplasmic reticulum stress response factor CHOP-10 protects against hypoxia-induced neuronal death. J Biol Chem 285: 21329-21340.
    • (2010) J Biol Chem , vol.285 , pp. 21329-21340
    • Halterman, M.W.1    Gill, M.2    Dejesus, C.3    Ogihara, M.4    Schor, N.F.5    Federoff, H.J.6
  • 16
    • 75649142054 scopus 로고    scopus 로고
    • A unique modulator of endoplasmic reticulum stress-signalling pathways: The novel pharmacological properties of amiloride in glial cells
    • Hosoi T, Kume A, Otani K, Oba T, Ozawa K, (2010). A unique modulator of endoplasmic reticulum stress-signalling pathways: the novel pharmacological properties of amiloride in glial cells. Br J Pharmacol 159: 428-437.
    • (2010) Br J Pharmacol , vol.159 , pp. 428-437
    • Hosoi, T.1    Kume, A.2    Otani, K.3    Oba, T.4    Ozawa, K.5
  • 17
    • 0035917808 scopus 로고    scopus 로고
    • Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation
    • Jaakkola P, Mole DR, Tian YM, Wilson MI, Gielbert J, Gaskell SJ, et al. (2001). Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation. Science 292: 468-472.
    • (2001) Science , vol.292 , pp. 468-472
    • Jaakkola, P.1    Mole, D.R.2    Tian, Y.M.3    Wilson, M.I.4    Gielbert, J.5    Gaskell, S.J.6
  • 18
    • 84884725230 scopus 로고    scopus 로고
    • The role of HIF in cobalt-induced ischemic tolerance
    • Jones SM, Novak AE, Elliott JP, (2013). The role of HIF in cobalt-induced ischemic tolerance. Neuroscience 252: 420-430.
    • (2013) Neuroscience , vol.252 , pp. 420-430
    • Jones, S.M.1    Novak, A.E.2    Elliott, J.P.3
  • 19
    • 0033859860 scopus 로고    scopus 로고
    • Veratridine induces apoptotic death in bovine chromaffin cells through superoxide production
    • Jordan J, Galindo MF, Calvo S, Gonzalez-Garcia C, Cena V, (2000). Veratridine induces apoptotic death in bovine chromaffin cells through superoxide production. Br J Pharmacol 130: 1496-1504.
    • (2000) Br J Pharmacol , vol.130 , pp. 1496-1504
    • Jordan, J.1    Galindo, M.F.2    Calvo, S.3    Gonzalez-Garcia, C.4    Cena, V.5
  • 21
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
    • Livak KJ, Schmittgen TD, (2001). Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25: 402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 22
    • 32444433450 scopus 로고    scopus 로고
    • Hypoxia-induced energy stress regulates mRNA translation and cell growth
    • Liu L, Cash TP, Jones RG, Keith B, Thompson CB, Simon MC, (2006). Hypoxia-induced energy stress regulates mRNA translation and cell growth. Mol Cell 21: 521-531.
    • (2006) Mol Cell , vol.21 , pp. 521-531
    • Liu, L.1    Cash, T.P.2    Jones, R.G.3    Keith, B.4    Thompson, C.B.5    Simon, M.C.6
  • 23
    • 84856209830 scopus 로고    scopus 로고
    • HIF-1alpha is neuroprotective during the early phases of mild hypoxia in rat cortical neurons
    • Lopez-Hernandez B, Posadas I, Podlesniy P, Abad MA, Trullas R, Ceña V, (2012). HIF-1alpha is neuroprotective during the early phases of mild hypoxia in rat cortical neurons. Exp Neurol 233: 543-554.
    • (2012) Exp Neurol , vol.233 , pp. 543-554
    • Lopez-Hernandez, B.1    Posadas, I.2    Podlesniy, P.3    Abad, M.A.4    Trullas, R.5    Ceña, V.6
  • 24
    • 77950473770 scopus 로고    scopus 로고
    • Hsp70 and CHIP selectively mediate ubiquitination and degradation of hypoxia-inducible factor (HIF)-1alpha but Not HIF-2alpha
    • Luo W, Zhong J, Chang R, Hu H, Pandey A, Semenza GL, (2010). Hsp70 and CHIP selectively mediate ubiquitination and degradation of hypoxia-inducible factor (HIF)-1alpha but Not HIF-2alpha. J Biol Chem 285: 3651-3663.
    • (2010) J Biol Chem , vol.285 , pp. 3651-3663
    • Luo, W.1    Zhong, J.2    Chang, R.3    Hu, H.4    Pandey, A.5    Semenza, G.L.6
  • 26
    • 58049194159 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1 alpha under rapid enzymatic hypoxia: Cells sense decrements of oxygen but not hypoxia per se
    • Millonig G, Hegedusch S, Becker L, Seitz HK, Schuppan D, Mueller S, (2009). Hypoxia-inducible factor 1 alpha under rapid enzymatic hypoxia: cells sense decrements of oxygen but not hypoxia per se. Free Radic Biol Med 46: 182-191.
    • (2009) Free Radic Biol Med , vol.46 , pp. 182-191
    • Millonig, G.1    Hegedusch, S.2    Becker, L.3    Seitz, H.K.4    Schuppan, D.5    Mueller, S.6
  • 27
    • 0037072937 scopus 로고    scopus 로고
    • An endoplasmic reticulum stress-specific caspase cascade in apoptosis. Cytochrome c-independent activation of caspase-9 by caspase-12
    • Morishima N, Nakanishi K, Takenouchi H, Shibata T, Yasuhiko Y, (2002). An endoplasmic reticulum stress-specific caspase cascade in apoptosis. Cytochrome c-independent activation of caspase-9 by caspase-12. J Biol Chem 277: 34287-34294.
    • (2002) J Biol Chem , vol.277 , pp. 34287-34294
    • Morishima, N.1    Nakanishi, K.2    Takenouchi, H.3    Shibata, T.4    Yasuhiko, Y.5
  • 28
    • 0034698878 scopus 로고    scopus 로고
    • Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis
    • Nakagawa T, Yuan J, (2000). Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis. J Cell Biol 150: 887-894.
    • (2000) J Cell Biol , vol.150 , pp. 887-894
    • Nakagawa, T.1    Yuan, J.2
  • 29
    • 84879368095 scopus 로고    scopus 로고
    • Restoring endoplasmic reticulum homeostasis improves functional recovery after spinal cord injury
    • Ohri SS, Hetman M, Whittemore SR, (2013). Restoring endoplasmic reticulum homeostasis improves functional recovery after spinal cord injury. Neurobiol Dis 58: 29-37.
    • (2013) Neurobiol Dis , vol.58 , pp. 29-37
    • Ohri, S.S.1    Hetman, M.2    Whittemore, S.R.3
  • 30
    • 79251600505 scopus 로고    scopus 로고
    • Overexpressing GRP78 influences Ca2+ handling and function of mitochondria in astrocytes after ischemia-like stress
    • Ouyang YB, Xu LJ, Emery JF, Lee AS, Giffard RG, (2011). Overexpressing GRP78 influences Ca2+ handling and function of mitochondria in astrocytes after ischemia-like stress. Mitochondrion 11: 279-286.
    • (2011) Mitochondrion , vol.11 , pp. 279-286
    • Ouyang, Y.B.1    Xu, L.J.2    Emery, J.F.3    Lee, A.S.4    Giffard, R.G.5
  • 31
    • 84864752911 scopus 로고    scopus 로고
    • Beneficial effect of taurine on hypoxia- and glutamate-induced endoplasmic reticulum stress pathways in primary neuronal culture
    • Pan C, Prentice H, Price AL, Wu JY, (2012). Beneficial effect of taurine on hypoxia- and glutamate-induced endoplasmic reticulum stress pathways in primary neuronal culture. Amino Acids 43: 845-855.
    • (2012) Amino Acids , vol.43 , pp. 845-855
    • Pan, C.1    Prentice, H.2    Price, A.L.3    Wu, J.Y.4
  • 32
    • 84891791940 scopus 로고    scopus 로고
    • The IUPHAR/BPS Guide to PHARMACOLOGY: An expert-driven knowledge base of drug targets and their ligands
    • NC-IUPHAR
    • Pawson AJ, Sharman JL, Benson HE, Faccenda E, Alexander SP, Buneman OP, et al.; NC-IUPHAR (2014). The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledge base of drug targets and their ligands. Nucl Acids Res 42 (Database Issue): D1098-D1106.
    • (2014) Nucl Acids Res , vol.42 , Issue.DATABASE ISSUE , pp. D1098-D1106
    • Pawson, A.J.1    Sharman, J.L.2    Benson, H.E.3    Faccenda, E.4    Alexander, S.P.5    Buneman, O.P.6
  • 34
    • 84865540583 scopus 로고    scopus 로고
    • Enhanced docetaxel-mediated cytotoxicity in human prostate cancer cells through knockdown of cofilin-1 by carbon nanohorn delivered siRNA
    • Perez-Martinez FC, Carrion B, Lucio MI, Rubio N, Herrero MA, Vazquez E, et al. (2012). Enhanced docetaxel-mediated cytotoxicity in human prostate cancer cells through knockdown of cofilin-1 by carbon nanohorn delivered siRNA. Biomaterials 33: 8152-8159.
    • (2012) Biomaterials , vol.33 , pp. 8152-8159
    • Perez-Martinez, F.C.1    Carrion, B.2    Lucio, M.I.3    Rubio, N.4    Herrero, M.A.5    Vazquez, E.6
  • 35
    • 33847624535 scopus 로고    scopus 로고
    • Acetaminophen potentiates staurosporine-induced death in a human neuroblastoma cell line
    • Posadas I, Vellecco V, Santos P, Prieto-Lloret J, Ceña V, (2007). Acetaminophen potentiates staurosporine-induced death in a human neuroblastoma cell line. Br J Pharmacol 150: 577-585.
    • (2007) Br J Pharmacol , vol.150 , pp. 577-585
    • Posadas, I.1    Vellecco, V.2    Santos, P.3    Prieto-Lloret, J.4    Ceña, V.5
  • 36
    • 63949086284 scopus 로고    scopus 로고
    • Highly efficient transfection of rat cortical neurons using carbosilane dendrimers unveils a neuroprotective role for HIF-1alpha in early chemical hypoxia-mediated neurotoxicity
    • Posadas I, Lopez-Hernandez B, Clemente MI, Jimenez JL, Ortega P, de la Mata J, et al. (2009). Highly efficient transfection of rat cortical neurons using carbosilane dendrimers unveils a neuroprotective role for HIF-1alpha in early chemical hypoxia-mediated neurotoxicity. Pharm Res 26: 1181-1191.
    • (2009) Pharm Res , vol.26 , pp. 1181-1191
    • Posadas, I.1    Lopez-Hernandez, B.2    Clemente, M.I.3    Jimenez, J.L.4    Ortega, P.5    De La Mata, J.6
  • 38
    • 84855932980 scopus 로고    scopus 로고
    • Cofilin activation mediates Bax translocation to mitochondria during excitotoxic neuronal death
    • Posadas I, Perez-Martinez FC, Guerra J, Sanchez-Verdu P, Ceña V, (2012). Cofilin activation mediates Bax translocation to mitochondria during excitotoxic neuronal death. J Neurochem 120: 515-527.
    • (2012) J Neurochem , vol.120 , pp. 515-527
    • Posadas, I.1    Perez-Martinez, F.C.2    Guerra, J.3    Sanchez-Verdu, P.4    Ceña, V.5
  • 39
    • 0037077254 scopus 로고    scopus 로고
    • Coupling endoplasmic reticulum stress to the cell death program. An Apaf-1-independent intrinsic pathway
    • Rao RV, Castro-Obregon S, Frankowski H, Schuler M, Stoka V, del Rio G, et al. (2002). Coupling endoplasmic reticulum stress to the cell death program. An Apaf-1-independent intrinsic pathway. J Biol Chem 277: 21836-21842.
    • (2002) J Biol Chem , vol.277 , pp. 21836-21842
    • Rao, R.V.1    Castro-Obregon, S.2    Frankowski, H.3    Schuler, M.4    Stoka, V.5    Del Rio, G.6
  • 41
    • 0032053169 scopus 로고    scopus 로고
    • Oxygen sensing, hypoxia-inducible factor-1 and the regulation of mammalian gene expression
    • Ratcliffe PJ, O'Rourke JF, Maxwell PH, Pugh CW, (1998). Oxygen sensing, hypoxia-inducible factor-1 and the regulation of mammalian gene expression. J Exp Biol 201: 1153-1162.
    • (1998) J Exp Biol , vol.201 , pp. 1153-1162
    • Ratcliffe, P.J.1    O'Rourke, J.F.2    Maxwell, P.H.3    Pugh, C.W.4
  • 43
    • 0032566706 scopus 로고    scopus 로고
    • Induction of hypoxia inducible factor 1 by oxygen glucose deprivation is attenuated by hypoxic preconditioning in rat cultured neurons
    • Ruscher K, Isaev N, Trendelenburg G, Weih M, Iurato L, Meisel A, et al. (1998). Induction of hypoxia inducible factor 1 by oxygen glucose deprivation is attenuated by hypoxic preconditioning in rat cultured neurons. Neurosci Lett 254: 117-120.
    • (1998) Neurosci Lett , vol.254 , pp. 117-120
    • Ruscher, K.1    Isaev, N.2    Trendelenburg, G.3    Weih, M.4    Iurato, L.5    Meisel, A.6
  • 44
    • 0034006016 scopus 로고    scopus 로고
    • HIF-1: Mediator of physiological and pathophysiological responses to hypoxia
    • Semenza GL, (2000). HIF-1: mediator of physiological and pathophysiological responses to hypoxia. J Appl Physiol 88: 1474-1480.
    • (2000) J Appl Physiol , vol.88 , pp. 1474-1480
    • Semenza, G.L.1
  • 45
    • 56149089262 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1 and cancer pathogenesis
    • Semenza GL, (2008). Hypoxia-inducible factor 1 and cancer pathogenesis. IUBMB Life 60: 591-597.
    • (2008) IUBMB Life , vol.60 , pp. 591-597
    • Semenza, G.L.1
  • 47
    • 0036063247 scopus 로고    scopus 로고
    • BiP binding keeps ATF6 at bay
    • Sommer T, Jarosch E, (2002). BiP binding keeps ATF6 at bay. Dev Cell 3: 1-2.
    • (2002) Dev Cell , vol.3 , pp. 1-2
    • Sommer, T.1    Jarosch, E.2
  • 49
    • 1342305497 scopus 로고    scopus 로고
    • Caspase-12 and ER-stress-mediated apoptosis: The story so far
    • Szegezdi E, Fitzgerald U, Samali A, (2003). Caspase-12 and ER-stress-mediated apoptosis: the story so far. Ann N Y Acad Sci 1010: 186-194.
    • (2003) Ann N y Acad Sci , vol.1010 , pp. 186-194
    • Szegezdi, E.1    Fitzgerald, U.2    Samali, A.3
  • 50
    • 79957936182 scopus 로고    scopus 로고
    • Bcl-x(L) blocks a mitochondrial inner membrane channel and prevents Ca2+ overload-mediated cell death
    • Tornero D, Posadas I, Ceña V, (2011). Bcl-x(L) blocks a mitochondrial inner membrane channel and prevents Ca2+ overload-mediated cell death. PLoS ONE 6: e20423.
    • (2011) PLoS ONE , vol.6 , pp. e20423
    • Tornero, D.1    Posadas, I.2    Ceña, V.3
  • 51
    • 33749262336 scopus 로고    scopus 로고
    • Cobalt induces hypoxia-inducible factor-1alpha (HIF-1alpha) in HeLa cells by an iron-independent, but ROS-, PI-3K- and MAPK-dependent mechanism
    • Triantafyllou A, Liakos P, Tsakalof A, Georgatsou E, Simos G, Bonanou S, (2006). Cobalt induces hypoxia-inducible factor-1alpha (HIF-1alpha) in HeLa cells by an iron-independent, but ROS-, PI-3K- and MAPK-dependent mechanism. Free Radic Res 40: 847-856.
    • (2006) Free Radic Res , vol.40 , pp. 847-856
    • Triantafyllou, A.1    Liakos, P.2    Tsakalof, A.3    Georgatsou, E.4    Simos, G.5    Bonanou, S.6
  • 52
    • 2442544693 scopus 로고    scopus 로고
    • Prolonged hypoxia differentially regulates hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha expression in lung epithelial cells: Implication of natural antisense HIF-1alpha
    • Uchida T, Rossignol F, Matthay MA, Mounier R, Couette S, Clottes E, et al. (2004). Prolonged hypoxia differentially regulates hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha expression in lung epithelial cells: implication of natural antisense HIF-1alpha. J Biol Chem 279: 14871-14878.
    • (2004) J Biol Chem , vol.279 , pp. 14871-14878
    • Uchida, T.1    Rossignol, F.2    Matthay, M.A.3    Mounier, R.4    Couette, S.5    Clottes, E.6
  • 53
    • 84861652703 scopus 로고    scopus 로고
    • The central role of initiator caspase-9 in apoptosis signal transduction and the regulation of its activation and activity on the apoptosome
    • Wurstle ML, Laussmann MA, Rehm M, (2012). The central role of initiator caspase-9 in apoptosis signal transduction and the regulation of its activation and activity on the apoptosome. Exp Cell Res 318: 1213-1220.
    • (2012) Exp Cell Res , vol.318 , pp. 1213-1220
    • Wurstle, M.L.1    Laussmann, M.A.2    Rehm, M.3
  • 54
    • 26444442450 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress: Cell life and death decisions
    • Xu C, Bailly-Maitre B, Reed JC, (2005). Endoplasmic reticulum stress: cell life and death decisions. J Clin Invest 115: 2656-2664.
    • (2005) J Clin Invest , vol.115 , pp. 2656-2664
    • Xu, C.1    Bailly-Maitre, B.2    Reed, J.C.3
  • 55
    • 0037844847 scopus 로고    scopus 로고
    • Cobalt inhibits the interaction between hypoxia-inducible factor-alpha and von Hippel-Lindau protein by direct binding to hypoxia-inducible factor-alpha
    • Yuan Y, Hilliard G, Ferguson T, Millhorn DE, (2003). Cobalt inhibits the interaction between hypoxia-inducible factor-alpha and von Hippel-Lindau protein by direct binding to hypoxia-inducible factor-alpha. J Biol Chem 278: 15911-15916.
    • (2003) J Biol Chem , vol.278 , pp. 15911-15916
    • Yuan, Y.1    Hilliard, G.2    Ferguson, T.3    Millhorn, D.E.4
  • 56
    • 34247614521 scopus 로고    scopus 로고
    • HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity
    • Zhang H, Gao P, Fukuda R, Kumar G, Krishnamachary B, Zeller KI, et al. (2007). HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity. Cancer Cell 11: 407-420.
    • (2007) Cancer Cell , vol.11 , pp. 407-420
    • Zhang, H.1    Gao, P.2    Fukuda, R.3    Kumar, G.4    Krishnamachary, B.5    Zeller, K.I.6
  • 57
    • 0033596980 scopus 로고    scopus 로고
    • An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9
    • Zou H, Li Y, Liu X, Wang X, (1999). An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9. J Biol Chem 274: 11549-11556.
    • (1999) J Biol Chem , vol.274 , pp. 11549-11556
    • Zou, H.1    Li, Y.2    Liu, X.3    Wang, X.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.