Δ9-tetrahydrocannabinol-mediated epigenetic modifications elicit myeloid-derived suppressor cell activation via STAT3/S100A8

Journal of Leukocyte Biology

Volumn 97, Issue 4, 2015, Pages 677-688

  Sido, Jessica Margaret ^a   Yang, Xiaoming ^a   Nagarkatti, Prakash S ^a   Nagarkatti, Mitzi ^a,b  

^a UNIVERSITY OF SOUTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b WJB Dorn VA Medical Center   (United States)

Author keywords

Arginase 1; Cannabinoid; DNA methylation; T cell suppression

Indexed keywords

ARGINASE 1; CALCIUM BINDING PROTEIN; CALGRANULIN A; DNA METHYLTRANSFERASE 3A; DNA METHYLTRANSFERASE 3B; DRONABINOL; STAT3 PROTEIN; ARG1 PROTEIN, MOUSE; ARGINASE; DNA (CYTOSINE 5) METHYLTRANSFERASE; S100A8 PROTEIN, MOUSE; STAT3 PROTEIN, MOUSE;

ANIMAL CELL; ARTICLE; CANCER MODEL; CELL DIFFERENTIATION; CONTROLLED STUDY; EPIGENETICS; FEMALE; IMMUNE EVASION; INFLAMMATION; METHYLATION; MOUSE; MYELOID DERIVED SUPPRESSOR CELL; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; SUPPRESSOR CELL; TUMOR IMMUNITY; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; BONE MARROW CELL; C57BL MOUSE; CYTOLOGY; DNA METHYLATION; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; GENETICS; GERMFREE ANIMAL; IMMUNOLOGICAL TOLERANCE; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; METABOLISM; PHYSIOLOGY; REGULATORY T LYMPHOCYTE;

CANNABIS SATIVA; MUS;

ANIMALS; ARGINASE; CALGRANULIN A; CELL DIFFERENTIATION; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; DRONABINOL; EPIGENESIS, GENETIC; FEMALE; GENE EXPRESSION REGULATION; IMMUNE TOLERANCE; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MYELOID CELLS; PROMOTER REGIONS, GENETIC; SPECIFIC PATHOGEN-FREE ORGANISMS; STAT3 TRANSCRIPTION FACTOR; T-LYMPHOCYTES, REGULATORY;

EID: 84929192483     PISSN: 07415400     EISSN: 19383673     Source Type: Journal    
DOI: 10.1189/jlb.1A1014-479R     Document Type: Article

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