ATP stimulates PGE2/cyclin D1-dependent VSMCs proliferation via STAT3 activation: Role of PKCs-dependent NADPH oxidase/ROS generation

Biochemical Pharmacology

Volumn 85, Issue 7, 2013, Pages 954-964

  Lee, I Ta ^a   Lin, Chih Chung ^a   Wang, Chao Hung ^b   Cherng, Wen Jin ^b   Wang, Jong Shyan ^b,c   Yang, Chuen Mao ^a,b  

^a CHANG GUNG UNIVERSITY   (Taiwan)

^b CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^c CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

Author keywords

Cyclin D1; Cyclooxygenase 2; Cytosolic phospholipase A2; NADPH oxidase

Indexed keywords

ADENOSINE TRIPHOSPHATE; CYCLIN D1; CYCLOOXYGENASE 2; CYTOSOLIC PHOSPHOLIPASE A2; DIPHENYLIODONIUM SALT; PROSTAGLANDIN E2; PROTEIN KINASE C; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; STAT3 PROTEIN;

ARTICLE; CELL PROLIFERATION; ENZYME ACTIVITY; PRIORITY JOURNAL; PROMOTER REGION; PROSTAGLANDIN SYNTHESIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGULATORY MECHANISM; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE CELL;

ADENOSINE TRIPHOSPHATE; ANIMALS; CELL PROLIFERATION; CELLS, CULTURED; CYCLIN D1; CYCLOOXYGENASE 2; MALE; MULTIENZYME COMPLEXES; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; NADH, NADPH OXIDOREDUCTASES; PHOSPHOLIPASES A2; PROTEIN KINASE C; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR;

EID: 84874658797     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2012.12.016     Document Type: Article

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