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Volumn 338, Issue 3, 2011, Pages 819-828

Targeting cannabinoid receptors as a novel approach in the treatment of graft-versus-host disease: Evidence from an experimental murine model

Author keywords

[No Author keywords available]

Indexed keywords

CANNABINOID 1 RECEPTOR; CANNABINOID 1 RECEPTOR ANTAGONIST; CANNABINOID 2 RECEPTOR; CANNABINOID 2 RECEPTOR ANTAGONIST; CANNABINOID RECEPTOR; CANNABINOID RECEPTOR ANTAGONIST; DRONABINOL; GAMMA INTERFERON; INTERLEUKIN 2; TRANSCRIPTION FACTOR FOXP3; UNCLASSIFIED DRUG;

EID: 80052168226     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.111.182717     Document Type: Article
Times cited : (34)

References (41)
  • 1
    • 0026559448 scopus 로고
    • Increasing utilization of allogeneic bone marrow transplantation. Results of the 1988-1990 survey
    • Bortin MM, Horowitz MM, and Rimm AA (1992) Increasing utilization of allogeneic bone marrow transplantation. Results of the 1988-1990 survey. Ann Intern Med 116:505-512.
    • (1992) Ann Intern Med , vol.116 , pp. 505-512
    • Bortin, M.M.1    Horowitz, M.M.2    Rimm, A.A.3
  • 2
    • 55549106484 scopus 로고    scopus 로고
    • Graft-versus-host disease: Suppression by statins
    • Broady R and Levings MK (2008) Graft-versus-host disease: suppression by statins. Nat Med 14:1155-1156.
    • (2008) Nat Med , vol.14 , pp. 1155-1156
    • Broady, R.1    Levings, M.K.2
  • 3
    • 0024949338 scopus 로고
    • Clinical studies of allogeneic marrow transplantation in patients with acute non-lymphoblastic leukaemia
    • Buckner CD and Clift RA (1989) Clinical studies of allogeneic marrow transplantation in patients with acute non-lymphoblastic leukaemia. Seattle Marrow Transplant Team. Bone Marrow Transplant 4(Suppl 3):82. (Pubitemid 20110689)
    • (1989) Bone Marrow Transplantation , vol.4 , Issue.SUPPL. 3 , pp. 82
    • Buckner, C.D.1    Clift, R.A.2
  • 5
    • 26844566936 scopus 로고    scopus 로고
    • Toxicity and carcinogenicity of Δ9-tetrahydrocannabinol in Fischer rats and B6C3F1 mice
    • Chan PC, Sills RC, Braun AG, Haseman JK, and Bucher JR (1996) Toxicity and carcinogenicity of Δ9-tetrahydrocannabinol in Fischer rats and B6C3F1 mice. Fundam Appl Toxicol 30:109-117.
    • (1996) Fundam Appl Toxicol , vol.30 , pp. 109-117
    • Chan, P.C.1    Sills, R.C.2    Braun, A.G.3    Haseman, J.K.4    Bucher, J.R.5
  • 6
    • 4043179097 scopus 로고    scopus 로고
    • Activation through cannabinoid receptors 1 and 2 on dendritic cells triggers NF-κB-dependent apoptosis: Novel role for endogenous and exogenous cannabinoids in immunoregulation
    • Do Y, McKallip RJ, Nagarkatti M, and Nagarkatti PS (2004) Activation through cannabinoid receptors 1 and 2 on dendritic cells triggers NF-κB-dependent apoptosis: novel role for endogenous and exogenous cannabinoids in immunoregulation. J Immunol 173:2373-2382. (Pubitemid 39063093)
    • (2004) Journal of Immunology , vol.173 , Issue.4 , pp. 2373-2382
    • Do, Y.1    McKallip, R.J.2    Nagarkatti, M.3    Nagarkatti, P.S.4
  • 7
    • 0025963233 scopus 로고
    • Graft-versus-host disease
    • Ferrara JL and Deeg HJ (1991) Graft-versus-host disease. N Engl J Med 324:667-674.
    • (1991) N Engl J Med , vol.324 , pp. 667-674
    • Ferrara, J.L.1    Deeg, H.J.2
  • 9
    • 0025802826 scopus 로고
    • Repopulation of host lymphohematopoietic systems by donor cells during graft-versus-host reaction in unirradiated adult F1 mice injected with parental lymphocytes
    • Hakim FT, Sharrow SO, Payne S, and Shearer GM (1991) Repopulation of host lymphohematopoietic systems by donor cells during graft-versus-host reaction in unirradiated adult F1 mice injected with parental lymphocytes. J Immunol 146:2108-2115.
    • (1991) J Immunol , vol.146 , pp. 2108-2115
    • Hakim, F.T.1    Sharrow, S.O.2    Payne, S.3    Shearer, G.M.4
  • 10
    • 11944262124 scopus 로고    scopus 로고
    • Cannabinoids and cancer: Causation, remediation, and palliation
    • DOI 10.1016/S1470-2045(04)01711-5, PII S1470204504017115
    • Hall W, Christie M, and Currow D (2005) Cannabinoids and cancer: causation, remediation, and palliation. Lancet Oncol 6:35-42. (Pubitemid 40100410)
    • (2005) Lancet Oncology , vol.6 , Issue.1 , pp. 35-42
    • Hall, W.1    Christie, M.2    Currow, D.3
  • 11
    • 45749086074 scopus 로고    scopus 로고
    • Attenuation of experimental autoimmune hepatitis by exogenous and endogenous cannabinoids: Involvement of regulatory T cells
    • DOI 10.1124/mol.108.047035
    • Hegde VL, Hegde S, Cravatt BF, Hofseth LJ, Nagarkatti M, and Nagarkatti PS (2008) Attenuation of experimental autoimmune hepatitis by exogenous and endogenous cannabinoids: involvement of regulatory T cells. Mol Pharmacol 74:20-33. (Pubitemid 351872155)
    • (2008) Molecular Pharmacology , vol.74 , Issue.1 , pp. 20-33
    • Hegde, V.L.1    Hegde, S.2    Cravatt, B.F.3    Hofseth, L.J.4    Nagarkatti, M.5    Nagarkatti, P.S.6
  • 12
    • 78649605467 scopus 로고    scopus 로고
    • Cannabinoid receptor activation leads to massive mobilization of myeloid-derived suppressor cells with potent immunosuppressive properties
    • Hegde VL, Nagarkatti M, and Nagarkatti PS (2010) Cannabinoid receptor activation leads to massive mobilization of myeloid-derived suppressor cells with potent immunosuppressive properties. Eur J Immunol 40:3358-3371.
    • (2010) Eur J Immunol , vol.40 , pp. 3358-3371
    • Hegde, V.L.1    Nagarkatti, M.2    Nagarkatti, P.S.3
  • 13
    • 77952593814 scopus 로고    scopus 로고
    • The effects of Δ-tetrahydrocannabinol and cannabidiol alone and in combination on damage, inflammation and in vitro motility disturbances in rat colitis
    • Jamontt JM, Molleman A, Pertwee RG, and Parsons ME (2010) The effects of Δ-tetrahydrocannabinol and cannabidiol alone and in combination on damage, inflammation and in vitro motility disturbances in rat colitis. Br J Pharmacol 160:712-723.
    • (2010) Br J Pharmacol , vol.160 , pp. 712-723
    • Jamontt, J.M.1    Molleman, A.2    Pertwee, R.G.3    Parsons, M.E.4
  • 14
    • 33748417610 scopus 로고    scopus 로고
    • Δ9-tetrahydrocannabinol-induced apoptosis in Jurkat leukemia T cells is regulated by translocation of bad to mitochondria
    • DOI 10.1158/1541-7786.MCR-05-0193
    • Jia W, Hegde VL, Singh NP, Sisco D, Grant S, Nagarkatti M, and Nagarkatti PS (2006) Δ9-Tetrahydrocannabinol-induced apoptosis in Jurkat leukemia T cells is regulated by translocation of Bad to mitochondria. Mol Cancer Res 4:549-562. (Pubitemid 44341365)
    • (2006) Molecular Cancer Research , vol.4 , Issue.8 , pp. 549-562
    • Jia, W.1    Hegde, V.L.2    Singh, N.P.3    Sisco, D.4    Grant, S.5    Nagarkatti, M.6    Nagarkatti, P.S.7
  • 17
    • 18844400058 scopus 로고    scopus 로고
    • Cannabinoid-based drugs as anti-inflammatory therapeutics
    • Klein TW (2005) Cannabinoid-based drugs as anti-inflammatory therapeutics. Nat Rev Immunol 5:400-411.
    • (2005) Nat Rev Immunol , vol.5 , pp. 400-411
    • Klein, T.W.1
  • 18
    • 0034660138 scopus 로고    scopus 로고
    • Δ9-Tetrahydrocannabinol treatment suppresses immunity and early IFN-γ, IL-12, and IL-12 receptor β2 responses to Legionella pneumophila infection
    • Klein TW, Newton CA, Nakachi N, and Friedman H (2000) Δ9-Tetrahydrocannabinol treatment suppresses immunity and early IFN-γ, IL-12, and IL-12 receptor β2 responses to Legionella pneumophila infection. J Immunol 164:6461-6466.
    • (2000) J Immunol , vol.164 , pp. 6461-6466
    • Klein, T.W.1    Newton, C.A.2    Nakachi, N.3    Friedman, H.4
  • 19
    • 0018257740 scopus 로고
    • Lethal graft versus host disease after bone marrow transplantation across minor histocompatibility barriers in mice. Prevention by removing mature T cells from marrow
    • Korngold R and Sprent J (1978) Lethal graft-versus-host disease after bone marrow transplantation across minor histocompatibility barriers in mice. Prevention by removing mature T cells from marrow. J Exp Med 148:1687-1698. (Pubitemid 9084041)
    • (1978) Journal of Experimental Medicine , vol.148 , Issue.6 , pp. 1687-1698
    • Korngold, R.1    Sprent, J.2
  • 20
    • 20544444202 scopus 로고    scopus 로고
    • 9- tetrahydrocannabinol (THC)-induced apoptosis of Jurkat cells
    • DOI 10.1016/j.leukres.2005.01.014, PII S0145212605000615
    • Lombard C, Nagarkatti M, and Nagarkatti PS (2005) Targeting cannabinoid receptors to treat leukemia: role of cross-talk between extrinsic and intrinsic pathways in Δ9-tetrahydrocannabinol (THC)-induced apoptosis of Jurkat cells. Leuk Res 29:915-922. (Pubitemid 40840719)
    • (2005) Leukemia Research , vol.29 , Issue.8 , pp. 915-922
    • Lombard, C.1    Nagarkatti, M.2    Nagarkatti, P.S.3
  • 21
    • 33144480327 scopus 로고    scopus 로고
    • Cannabinoid receptors as therapeutic targets
    • Mackie K (2006) Cannabinoid receptors as therapeutic targets. Annu Rev Pharmacol Toxicol 46:101-122.
    • (2006) Annu Rev Pharmacol Toxicol , vol.46 , pp. 101-122
    • Mackie, K.1
  • 23
    • 0037100312 scopus 로고    scopus 로고
    • Targeting CB2 cannabinoid receptors as a novel therapy to treat malignant lymphoblastic disease
    • DOI 10.1182/blood-2002-01-0098
    • McKallip RJ, Lombard C, Fisher M, Martin BR, Ryu S, Grant S, Nagarkatti PS, and Nagarkatti M (2002a) Targeting CB2 cannabinoid receptors as a novel therapy to treat malignant lymphoblastic disease. Blood 100:627-634. (Pubitemid 34761128)
    • (2002) Blood , vol.100 , Issue.2 , pp. 627-634
    • McKallip, R.J.1    Lombard, C.2    Fisher, M.3    Martin, B.R.4    Ryu, S.5    Grant, S.6    Nagarkatti, P.S.7    Nagarkatti, M.8
  • 25
    • 14844362003 scopus 로고    scopus 로고
    • Δ-9-tetrahydrocannabinol enhances breast cancer growth and metastasis by suppression of the antitumor immune response
    • McKallip RJ, Nagarkatti M, and Nagarkatti PS (2005) Δ-9- Tetrahydrocannabinol enhances breast cancer growth and metastasis by suppression of the antitumor immune response. J Immunol 174:3281-3289. (Pubitemid 40354031)
    • (2005) Journal of Immunology , vol.174 , Issue.6 , pp. 3281-3289
    • McKallip, R.J.1    Nagarkatti, M.2    Nagarkatti, P.S.3
  • 27
    • 0032127448 scopus 로고    scopus 로고
    • Involvement of Fas-mediated apoptosis in the hematopoietic progenitor cells of graft-versus-host reaction-associated myelosuppression
    • Mori T, Nishimura T, Ikeda Y, Hotta T, Yagita H, and Ando K (1998) Involvement of Fas-mediated apoptosis in the hematopoietic progenitor cells of graft-versus-host reaction-associated myelosuppression. Blood 92:101-107.
    • (1998) Blood , vol.92 , pp. 101-107
    • Mori, T.1    Nishimura, T.2    Ikeda, Y.3    Hotta, T.4    Yagita, H.5    Ando, K.6
  • 31
    • 65449146377 scopus 로고    scopus 로고
    • Emerging strategies for exploiting cannabinoid receptor agonists as medicines
    • Pertwee RG (2009) Emerging strategies for exploiting cannabinoid receptor agonists as medicines. Br J Pharmacol 156:397-411.
    • (2009) Br J Pharmacol , vol.156 , pp. 397-411
    • Pertwee, R.G.1
  • 33
    • 0023713979 scopus 로고
    • T cell depletion in bone marrow transplantation
    • Poynton CH (1988) T cell depletion in bone marrow transplantation. Bone Marrow Transplant 3:265-279.
    • (1988) Bone Marrow Transplant , vol.3 , pp. 265-279
    • Poynton, C.H.1
  • 34
    • 77449127143 scopus 로고    scopus 로고
    • Cannabidiol inhibits cancer cell invasion via up-regulation of tissue inhibitor of matrix metalloproteinases-1
    • Ramer R, Merkord J, Rohde H, and Hinz B (2010) Cannabidiol inhibits cancer cell invasion via up-regulation of tissue inhibitor of matrix metalloproteinases-1. Biochem Pharmacol 79:955-966.
    • (2010) Biochem Pharmacol , vol.79 , pp. 955-966
    • Ramer, R.1    Merkord, J.2    Rohde, H.3    Hinz, B.4
  • 36
    • 77954175124 scopus 로고    scopus 로고
    • Cannabinoid-induced apoptosis in immune cells as a pathway to immunosuppression
    • Rieder SA, Chauhan A, Singh U, Nagarkatti M, and Nagarkatti P (2010) Cannabinoid-induced apoptosis in immune cells as a pathway to immunosuppression. Immunobiology 215:598-605.
    • (2010) Immunobiology , vol.215 , pp. 598-605
    • Rieder, S.A.1    Chauhan, A.2    Singh, U.3    Nagarkatti, M.4    Nagarkatti, P.5
  • 37
    • 0022624255 scopus 로고
    • Methotrexate and cyclosporine compared with cyclosporine alone for prophylaxis of acute graft versus host disease after marrow transplantation for leukemia
    • Storb R, Deeg HJ, Whitehead J, Appelbaum F, Beatty P, Bensinger W, Buckner CD, Clift R, Doney K, and Farewell V (1986) Methotrexate and cyclosporine compared with cyclosporine alone for prophylaxis of acute graft versus host disease after marrow transplantation for leukemia. N Engl J Med 314:729-735. (Pubitemid 16124386)
    • (1986) New England Journal of Medicine , vol.314 , Issue.12 , pp. 729-735
    • Storb, R.1    Deeg, H.J.2    Whitehead, J.3
  • 38
    • 0023266683 scopus 로고
    • Role of cytotoxic T lymphocytes in the prevention of lupus-like disease occurring in a murine model of graft-vs-host disease
    • Via CS, Sharrow SO, and Shearer GM (1987) Role of cytotoxic T lymphocytes in the prevention of lupus-like disease occurring in a murine model of graft-vs-host disease. J Immunol 139:1840-1849. (Pubitemid 17141612)
    • (1987) Journal of Immunology , vol.139 , Issue.6 , pp. 1840-1849
    • Via, C.S.1    Sharrow, S.O.2    Shearer, G.M.3
  • 39
    • 0023879179 scopus 로고
    • T-cell interactions in autoimmunity: Insights from a murine model of graft-versus-host disease
    • Via CS and Shearer GM (1988) T-cell interactions in autoimmunity: insights from a murine model of graft-versus-host disease. Immunol Today 9:207-213.
    • (1988) Immunol Today , vol.9 , pp. 207-213
    • Via, C.S.1    Shearer, G.M.2
  • 40
    • 34247867901 scopus 로고    scopus 로고
    • Immunobiology of allogeneic hematopoietic stem cell transplantation
    • DOI 10.1146/annurev.immunol.25.022106.141606
    • Welniak LA, Blazar BR, and Murphy WJ (2007) Immunobiology of allogeneic hematopoietic stem cell transplantation. Annu Rev Immunol 25:139-170. (Pubitemid 46697905)
    • (2007) Annual Review of Immunology , vol.25 , pp. 139-170
    • Welniak, L.A.1    Blazar, B.R.2    Murphy, W.J.3
  • 41
    • 0023192261 scopus 로고
    • Suppression of B lymphocyte genesis in the bone marrow by systemic graft-versus-host reactions
    • Xenocostas A, Lapp WS, and Osmond DG (1987) Suppression of B lymphocyte genesis in the bone marrow by systemic graft-versus-host reactions. Transplantation 43:549-555. (Pubitemid 17065714)
    • (1987) Transplantation , vol.43 , Issue.4 , pp. 549-555
    • Xenocostas, A.1    Lapp, W.S.2    Osmond, D.G.3


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