Signal transducer and activator of transcription 3 (Stat3C) promotes myeloid-derived suppressor cell expansion and immune suppression during lung tumorigenesis

American Journal of Pathology

Volumn 179, Issue 4, 2011, Pages 2131-2141

  Wu, Lingyan ^a   Du, Hong ^a   Li, Yuan ^b   Qu, Peng ^a   Yan, Cong ^a  

^a INDIANA UNIVERSITY   (United States)

^b FUDAN UNIVERSITY SHANGHAI CANCER CENTER   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CD11B ANTIGEN; DOXYCYCLINE; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; STAT3 PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARCINOGENESIS; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL EXPANSION; CELL STIMULATION; CONTROLLED STUDY; IMMUNE DEFICIENCY; IMMUNOSUPPRESSIVE TREATMENT; INTRACELLULAR SIGNALING; LUNG CANCER; LUNG LAVAGE; MACROPHAGE; MONOCYTE; MOUSE; MYELOID DERIVED SUPRESSOR CELL; NONHUMAN; PHOSPHORYLATION; PLASMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SUPPRESSOR CELL; WILD TYPE;

ANIMALS; ANTIGENS, CD11; ANTIGENS, LY; BRONCHOALVEOLAR LAVAGE FLUID; CD4-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; COCULTURE TECHNIQUES; CYTOKINES; LUNG; LUNG NEOPLASMS; MACROPHAGES; MICE; MICE, TRANSGENIC; MYELOID CELLS; PNEUMOCYTES; STAT3 TRANSCRIPTION FACTOR; UP-REGULATION;

EID: 80053224991     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2011.06.028     Document Type: Article

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