Molecular basis for Fe(III)-independent curcumin potentiation of cystic fibrosis transmembrane conductance regulator activity

Biochemistry

Volumn 54, Issue 18, 2015, Pages 2828-2840

  Wang, Guangyu ^a,b,c  

^a UNIVERSITY OF ALABAMA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NEVADA SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; AROMATIC COMPOUNDS; BIOLOGICAL MEMBRANES;

CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATORS; DISULFIDE CROSS-LINKING; INTRACELLULAR LOOP; MOLECULAR MECHANISM; NUCLEOTIDE-BINDING DOMAIN; PHOSPHORYLATION SITES; POSITIVELY CHARGED; TRANS-MEMBRANE DOMAINS;

PHOSPHORYLATION;

CURCUMIN; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; IRON DERIVATIVE; NUCLEOTIDE BINDING DOMAIN 2 PROTEIN; NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG; CULTURE MEDIUM; CYCLIC AMP DEPENDENT PROTEIN KINASE; FERRIC ION;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL CULTURE; CROSS LINKING; CULTURE MEDIUM; DRUG POTENTIATION; HEK293 CELL LINE; HUMAN; HUMAN CELL; MOLECULAR BIOLOGY; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; ANIMAL; CHANNEL GATING; GENETICS; METABOLISM; MOUSE; MUTATION; PATCH CLAMP TECHNIQUE; PHOSPHORYLATION; PROTEIN TERTIARY STRUCTURE;

ANIMALS; CULTURE MEDIA; CURCUMIN; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; FERRIC COMPOUNDS; HEK293 CELLS; HUMANS; ION CHANNEL GATING; MICE; MUTATION; PATCH-CLAMP TECHNIQUES; PHOSPHORYLATION; PROTEIN STRUCTURE, TERTIARY;

EID: 84929190436     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/acs.biochem.5b00219     Document Type: Article

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