Interplay between inhibitory ferric and stimulatory curcumin regulates phosphorylation-dependent human cystic fibrosis transmembrane conductance regulator and Δf508 activity

Biochemistry

Volumn 54, Issue 7, 2015, Pages 1558-1566

  Wang, Guangyu ^a,b  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; CHEMICAL ACTIVATION; PHOSPHORYLATION;

BINDING INTERFACE; CURCUMIN; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATORS; INTRACELLULAR LOOP; MOLECULAR MECHANISM; PRE-TREATMENT; REGULATORY DOMAIN;

ETHYLENEDIAMINETETRAACETIC ACID;

CURCUMIN; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; EDETIC ACID; FERRIC ION; N ETHYLMALEIMIDE; CHELATING AGENT; NONSTEROID ANTIINFLAMMATORY AGENT;

ARTICLE; CONTROLLED STUDY; DRUG POTENTIATION; GENE MUTATION; HEK293 CELL LINE; HOMEOSTASIS; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; AGONISTS; ANTAGONISTS AND INHIBITORS; CYSTIC FIBROSIS; DRUG EFFECTS; GENETICS; METABOLISM; MUTATION; PHOSPHORYLATION;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CHELATING AGENTS; CURCUMIN; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; EDETIC ACID; FERRIC COMPOUNDS; HEK293 CELLS; HUMANS; MUTATION; PHOSPHORYLATION;

EID: 84923359475     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi501318h     Document Type: Article

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