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Volumn , Issue , 2012, Pages 2325-2347

Implication of oxidative stress-induced oncogenic signaling pathways as a treatment strategy for neurodegeneration and cancer

Author keywords

Alzheimer's disease; Cancer; Cell Cycle; Mitochondria; Oncogenes; Oxidative stress

Indexed keywords


EID: 84929138425     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-3-642-30018-9_206     Document Type: Chapter
Times cited : (16)

References (75)
  • 2
    • 84927514888 scopus 로고    scopus 로고
    • Mitochondria specific antioxidants and their derivatives in the context of the drug development for neurodegeneration and cancer
    • Aliev G, Palacios HH, Cacabelos P, Cacabelos R, Burzynski G, Burzynski SR (2012) Mitochondria specific antioxidants and their derivatives in the context of the drug development for neurodegeneration and cancer. Drug Des 2 (103). doi: 10.4172/2169-0138.100010370
    • (2012) Drug des , vol.2 , Issue.103
    • Aliev, G.1    Palacios, H.H.2    Cacabelos, P.3    Cacabelos, R.4    Burzynski, G.5    Burzynski, S.R.6
  • 3
    • 20044367108 scopus 로고    scopus 로고
    • Cell-cycle reentry and cell death in transgenic mice expressing nonmutant human tau isoforms
    • Andorfer C, Acker CM, Kress Y, Hof PR, Duff K, Davies P (2005) Cell-cycle reentry and cell death in transgenic mice expressing nonmutant human tau isoforms. J Neurosci 25(22):5446-5454. doi:10.1523/jneurosci.4637-04.2005
    • (2005) J Neurosci , vol.25 , Issue.22 , pp. 5446-5454
    • Andorfer, C.1    Acker, C.M.2    Kress, Y.3    Hof, P.R.4    Duff, K.5    Davies, P.6
  • 4
    • 1242341923 scopus 로고    scopus 로고
    • Incipient Alzheimer's disease: Microarray correlation analyses reveal major transcriptional and tumor suppressor responses
    • Blalock EM, Geddes JW, Chen KC, Porter NM, Markesbery WR, Landfield PW (2004) Incipient Alzheimer's disease: microarray correlation analyses reveal major transcriptional and tumor suppressor responses. Proc Natl Acad Sci USA 101(7):2173-2178. doi:10.1073/pnas. 0308512100
    • (2004) Proc Natl Acad Sci USA , vol.101 , Issue.7 , pp. 2173-2178
    • Blalock, E.M.1    Geddes, J.W.2    Chen, K.C.3    Porter, N.M.4    Markesbery, W.R.5    Landfield, P.W.6
  • 6
    • 33847723997 scopus 로고    scopus 로고
    • P53-dependent neuronal cell death in a DJ-1-deficient zebrafish model of Parkinson's disease
    • Bretaud S, Allen C, Ingham PW, Bandmann O (2007) p53-dependent neuronal cell death in a DJ-1-deficient zebrafish model of Parkinson's disease. J Neurochem 100(6):1626-1635. doi:10.1111/j.1471-4159.2006.04291.x
    • (2007) J Neurochem , vol.100 , Issue.6 , pp. 1626-1635
    • Bretaud, S.1    Allen, C.2    Ingham, P.W.3    Bandmann, O.4
  • 9
    • 33750052885 scopus 로고    scopus 로고
    • DJ-1, a cancer-And Parkinson's disease-Associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2
    • Clements CM, McNally RS, Conti BJ, Mak TW, Ting JPY (2006) DJ-1, a cancer-And Parkinson's disease-Associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2. PNAS 103(41):15091-15096. doi:10.1073/pnas.0607260103
    • (2006) PNAS , vol.103 , Issue.41 , pp. 15091-15096
    • Clements, C.M.1    McNally, R.S.2    Conti, B.J.3    Mak, T.W.4    Jpy, T.5
  • 10
    • 73849122773 scopus 로고    scopus 로고
    • Oxidative stress inhibits nuclear protein export by multiple mechanisms that target FG nucleoporins and Crm1
    • Crampton N, Kodiha M, Shrivastava S, Umar R, Stochaj U (2009) Oxidative stress inhibits nuclear protein export by multiple mechanisms that target FG nucleoporins and Crm1. Mol Biol Cell 20(24):5106-5116. doi:10.1091/mbc.E09-05-0397
    • (2009) Mol Biol Cell , vol.20 , Issue.24 , pp. 5106-5116
    • Crampton, N.1    Kodiha, M.2    Shrivastava, S.3    Umar, R.4    Stochaj, U.5
  • 11
    • 33749826587 scopus 로고    scopus 로고
    • P25/cyclindependent kinase 5 induces production and intraneuronal accumulation of amyloid b in vivo
    • Cruz JC, Kim D, Moy LY, Dobbin MM, Sun X, Bronson RT, Tsai L-H (2006) p25/cyclindependent kinase 5 induces production and intraneuronal accumulation of amyloid b in vivo. J Neurosci 26(41):10536-10541. doi:10.1523/jneurosci.3133-06.2006
    • (2006) J Neurosci , vol.26 , Issue.41 , pp. 10536-10541
    • Cruz, J.C.1    Kim, D.2    Moy, L.Y.3    Dobbin, M.M.4    Sun, X.5    Bronson, R.T.6    Tsai, L.-H.7
  • 12
    • 33644513730 scopus 로고    scopus 로고
    • Beyond PTEN mutations: The PI3K pathway as an integrator of multiple inputs during tumorigenesis
    • Cully M, You H, Levine AJ, Mak TW (2006) Beyond PTEN mutations: The PI3K pathway as an integrator of multiple inputs during tumorigenesis. Nat Rev Cancer 6(3):184-192. doi:10.1038/nrc1819
    • (2006) Nat Rev Cancer , vol.6 , Issue.3 , pp. 184-192
    • Cully, M.1    You, H.2    Levine, A.J.3    Mak, T.W.4
  • 13
    • 58249089343 scopus 로고    scopus 로고
    • Age-dependent deterioration of nuclear pore complexes causes a loss of nuclear integrity in postmitotic cells
    • D'Angelo MA, Raices M, Panowski SH, Hetzer MW (2009) Age-dependent deterioration of nuclear pore complexes causes a loss of nuclear integrity in postmitotic cells. Cell 136(2):284-295. doi:10.1016/j.cell.2008.11.037
    • (2009) Cell , vol.136 , Issue.2 , pp. 284-295
    • D'Angelo, M.A.1    Raices, M.2    Panowski, S.H.3    Hetzer, M.W.4
  • 14
    • 34250190649 scopus 로고    scopus 로고
    • Inhibition of PTEN by peroxynitrite activates the phosphoinositide-3-kinase/Akt neuroprotective signaling pathway
    • Delgado-Esteban M, Martin-Zanca D, Andres-Martin L, Almeida A, Bolanõs JP (2007) Inhibition of PTEN by peroxynitrite activates the phosphoinositide-3-kinase/Akt neuroprotective signaling pathway. J Neurochem 102(1):194-205. doi:10.1111/j.1471-4159.2007.04450.x
    • (2007) J Neurochem , vol.102 , Issue.1 , pp. 194-205
    • Delgado-Esteban, M.1    Martin-Zanca, D.2    Andres-Martin, L.3    Almeida, A.4    Bolanõs, J.P.5
  • 15
    • 58149268892 scopus 로고    scopus 로고
    • Retinoic acid attenuates b-Amyloid deposition and rescues memory deficits in an Alzheimer's disease transgenic mouse model
    • Ding Y, Qiao A, Wang Z, Goodwin JS, Lee E-S, Block ML, Allsbrook M, McDonald MP, Fan G-H (2008) Retinoic acid attenuates b-Amyloid deposition and rescues memory deficits in an Alzheimer's disease transgenic mouse model. J Neurosci 28(45):11622-11634. doi:10.1523/jneurosci.3153-08.2008
    • (2008) J Neurosci , vol.28 , Issue.45 , pp. 11622-11634
    • Ding, Y.1    Qiao, A.2    Wang, Z.3    Goodwin, J.S.4    Lee, E.-S.5    Block, M.L.6    Allsbrook, M.7    McDonald, M.P.8    Fan, G.-H.9
  • 16
    • 34248345577 scopus 로고    scopus 로고
    • BRCA1 may modulate neuronal cell cycle re-entry in Alzheimer disease
    • Evans TA (2007) BRCA1 may modulate neuronal cell cycle re-entry in Alzheimer disease. Int J Med Sci. doi:10.7150/ijms.4.140
    • (2007) J Med Sci
    • Evans, T.A.1
  • 18
    • 33744931650 scopus 로고    scopus 로고
    • Telomeres and telomerase in Alzheimer's disease: Epiphenomena or a new focus for therapeutic strategy
    • Franco S, Blasco MA, Siedlak SL, Harris PLR, Moreira PI, Perry G, Smith MA (2006) Telomeres and telomerase in Alzheimer's disease: epiphenomena or a new focus for therapeutic strategy? Alzheimer's Dement 2(3):164-168. doi:10.1016/j.jalz.2006.03.001
    • (2006) Alzheimer's Dement , vol.2 , Issue.3 , pp. 164-168
    • Franco, S.1    Blasco, M.A.2    Siedlak, S.L.3    Harris, P.L.R.4    Moreira, P.I.5    Perry, G.6    Smith, M.A.7
  • 19
    • 49649097747 scopus 로고    scopus 로고
    • Loss of PINK1 causes mitochondrial functional defects and increased sensitivity to oxidative stress
    • Gautier CA, Kitada T, Shen J (2008) Loss of PINK1 causes mitochondrial functional defects and increased sensitivity to oxidative stress. Proc Natl Acad Sci USA 105(32):11364-11369. doi:10.1073/pnas.0802076105
    • (2008) Proc Natl Acad Sci USA , vol.105 , Issue.32 , pp. 11364-11369
    • Gautier, C.A.1    Kitada, T.2    Shen, J.3
  • 21
    • 0033516567 scopus 로고    scopus 로고
    • Involvement of cell cycle elements, cyclin-dependent kinases, pRb, and E2F • DP, in B-Amyloid-induced neuronal death
    • Giovanni A, Wirtz-Brugger F, Keramaris E, Slack R, Park DS (1999) Involvement of cell cycle elements, cyclin-dependent kinases, pRb, and E2F • DP, in B-Amyloid-induced neuronal death. J Biol Chem 274(27):19011-19016. doi:10.1074/jbc.274.27.19011
    • (1999) J Biol Chem , vol.274 , Issue.27 , pp. 19011-19016
    • Giovanni, A.1    Wirtz-Brugger, F.2    Keramaris, E.3    Slack, R.4    Park, D.S.5
  • 22
    • 34250361915 scopus 로고    scopus 로고
    • Structural determinants of the C-terminal helix-kink-helix motif essential for protein stability and survival promoting activity of DJ-1
    • Görner K, Holtorf E, Waak J, Pham T-T, Vogt-Weisenhorn DM, Wurst W, Haass C, Kahle PJ (2007) Structural determinants of the C-terminal helix-kink-helix motif essential for protein stability and survival promoting activity of DJ-1. J Biol Chem 282(18):13680-13691. doi:10.1074/jbc.M609821200
    • (2007) J Biol Chem , vol.282 , Issue.18 , pp. 13680-13691
    • Görner, K.1    Holtorf, E.2    Waak, J.3    Pham, T.-T.4    Vogt-Weisenhorn, D.M.5    Wurst, W.6    Haass, C.7    Kahle, P.J.8
  • 23
    • 16244391770 scopus 로고    scopus 로고
    • Activation of Akt/PKB, increased phosphorylation of Akt substrates and loss and altered distribution of Akt and PTEN are features of Alzheimer's disease pathology
    • Griffin RJ, Moloney A, Kelliher M, Johnston JA, Ravid R, Dockery P, O'Connor R, O'Neill C (2005) Activation of Akt/PKB, increased phosphorylation of Akt substrates and loss and altered distribution of Akt and PTEN are features of Alzheimer's disease pathology. J Neurochem 93(1):105-117. doi:10.1111/j.1471-4159.2004.02949.x
    • (2005) J Neurochem , vol.93 , Issue.1 , pp. 105-117
    • Griffin, R.J.1    Moloney, A.2    Kelliher, M.3    Johnston, J.A.4    Ravid, R.5    Dockery, P.6    O'Connor, R.7    O'Neill, C.8
  • 24
    • 60649083945 scopus 로고    scopus 로고
    • Cell cycle re-entry mediated neurodegeneration and its treatment role in the pathogenesis of Alzheimer's disease
    • H-g L, Casadesus G, Zhu X, Castellani RJ, McShea A, Perry G, Petersen RB, Bajic V, Smith MA (2009) Cell cycle re-entry mediated neurodegeneration and its treatment role in the pathogenesis of Alzheimer's disease. Neurochem Int 54(2):84-88. doi:10.1016/j.neuint.2008.10.013
    • (2009) Neurochem Int , vol.54 , Issue.2 , pp. 84-88
    • H-G, L.1    Casadesus, G.2    Zhu, X.3    Castellani, R.J.4    McShea, A.5    Perry, G.6    Petersen, R.B.7    Bajic, V.8    Smith, M.A.9
  • 27
    • 84866931832 scopus 로고    scopus 로고
    • Protective effects of the key compounds isolated from Corni fructus against b-Amyloid-induced neurotoxicity in PC12 cells
    • Hong SY, Jeong WS, Jun M (2012) Protective effects of the key compounds isolated from Corni fructus against b-Amyloid-induced neurotoxicity in PC12 cells. Molecules 17(9):10831-10845
    • (2012) Molecules , vol.17 , Issue.9 , pp. 10831-10845
    • Hong, S.Y.1    Jeong, W.S.2    Jun, M.3
  • 29
    • 22144465488 scopus 로고    scopus 로고
    • Interaction of DJ-1 with Daxx inhibits apoptosis signal-regulating kinase 1 activity and cell death
    • Junn E, Taniguchi H, Jeong BS, Zhao X, Ichijo H, MouradianMM(2005) Interaction of DJ-1 with Daxx inhibits apoptosis signal-regulating kinase 1 activity and cell death. Proc Natl Acad Sci USA 102(27):9691-9696. doi:10.1073/pnas.0409635102
    • (2005) Proc Natl Acad Sci USA , vol.102 , Issue.27 , pp. 9691-9696
    • Junn, E.1    Taniguchi, H.2    Jeong, B.S.3    Zhao, X.4    Ichijo, H.5    Mouradian, M.M.6
  • 30
    • 33644834046 scopus 로고    scopus 로고
    • Tumours and tremors: How PTEN regulation underlies both
    • Kim RH, Mak TW (2006) Tumours and tremors: how PTEN regulation underlies both. Br J Cancer 94(5):620-624. doi:10.1038/sj.bjc.6602994
    • (2006) Br J Cancer , vol.94 , Issue.5 , pp. 620-624
    • Kim, R.H.1    Mak, T.W.2
  • 32
    • 1842740232 scopus 로고    scopus 로고
    • Cysteine-106 of DJ-1 is themost sensitive cysteine residue to hydrogen peroxide-mediated oxidation in vivo in human umbilical vein endothelial cells
    • Kinumi T,Kimata J, Taira T, ArigaH,Niki E (2004)Cysteine-106 of DJ-1 is themost sensitive cysteine residue to hydrogen peroxide-mediated oxidation in vivo in human umbilical vein endothelial cells. Biochem Biophys Res Commun 317(3):722-728. doi:10.1016/j.bbrc.2004.03.110
    • (2004) Biochem Biophys Res Commun , vol.317 , Issue.3 , pp. 722-728
    • Kinumi, T.1    Kimata, J.2    Taira, T.3    Ariga, H.4    Niki, E.5
  • 33
    • 0037366104 scopus 로고    scopus 로고
    • Oxidative stress, cell cycle, and neurodegeneration
    • Klein JA, Ackerman SL (2003) Oxidative stress, cell cycle, and neurodegeneration. J Clin Invest 111(6):785-793. doi:10.1172/jci18182
    • (2003) J Clin Invest , vol.111 , Issue.6 , pp. 785-793
    • Klein, J.A.1    Ackerman, S.L.2
  • 34
    • 0036282745 scopus 로고    scopus 로고
    • Cdc2 phosphorylation of BAD links the cell cycle to the cell death machinery
    • Konishi Y, Lehtinen M, Donovan N, Bonni A (2002) Cdc2 phosphorylation of BAD links the cell cycle to the cell death machinery. Mol Cell 9(5):1005-1016
    • (2002) Mol Cell , vol.9 , Issue.5 , pp. 1005-1016
    • Konishi, Y.1    Lehtinen, M.2    Donovan, N.3    Bonni, A.4
  • 35
    • 0037443779 scopus 로고    scopus 로고
    • Tumor suppressor gene BRCA-1 is expressed by embryonic and adult neural stem cells and involved in cell proliferation
    • Korhonen L, Brännvall K, Skoglösa Y, Lindholm D (2003) Tumor suppressor gene BRCA-1 is expressed by embryonic and adult neural stem cells and involved in cell proliferation. J Neurosci Res 71(6):769-776
    • (2003) J Neurosci Res , vol.71 , Issue.6 , pp. 769-776
    • Korhonen, L.1    Brännvall, K.2    Skoglösa, Y.3    Lindholm, D.4
  • 36
    • 58249089339 scopus 로고    scopus 로고
    • Old nuclei spring new leaks
    • Kotwaliwale CV, Dernburg AF (2009) Old nuclei spring new leaks. Cell 136(2):211-212. doi:10.1016/j.cell.2009.01.004
    • (2009) Cell , vol.136 , Issue.2 , pp. 211-212
    • Kotwaliwale, C.V.1    Dernburg, A.F.2
  • 39
    • 0027246336 scopus 로고
    • Amyloid precursor protein in peripheral mononuclear cells is up-regulated with cell activation
    • Ledoux S, Rebai N, Dagenais A, Shaw IT, Nalbantoglu J, Sekaly RP, Cashman NR (1993) Amyloid precursor protein in peripheral mononuclear cells is up-regulated with cell activation. J Immunol 150(12):5566-5575
    • (1993) J Immunol , vol.150 , Issue.12 , pp. 5566-5575
    • Ledoux, S.1    Rebai, N.2    Dagenais, A.3    Shaw, I.T.4    Nalbantoglu, J.5    Sekaly, R.P.6    Cashman, N.R.7
  • 40
    • 0034912744 scopus 로고    scopus 로고
    • PTEN and myotubularin: Novel phosphoinositide phosphatases
    • Maehama T, Taylor GS, Dixon JE (2001) PTEN and myotubularin: novel phosphoinositide phosphatases. Annu Rev Biochem 70:247-279. doi:10.1146/annurev.biochem.70.1.247
    • (2001) Annu Rev Biochem , vol.70 , pp. 247-279
    • Maehama, T.1    Taylor, G.S.2    Dixon, J.E.3
  • 42
    • 0031982670 scopus 로고    scopus 로고
    • Presenilins, the endoplasmic reticulum, and neuronal apoptosis in Alzheimer's disease
    • Mattson MP, Guo Q, Furukawa K, Pedersen WA (1998) Presenilins, the endoplasmic reticulum, and neuronal apoptosis in Alzheimer's disease. J Neurochem 70(1):1-14
    • (1998) J Neurochem , vol.70 , Issue.1 , pp. 1-14
    • Mattson, M.P.1    Guo, Q.2    Furukawa, K.3    Pedersen, W.A.4
  • 43
    • 0032526423 scopus 로고    scopus 로고
    • B-Amyloid fibrils activate parallel mitogen-Activated protein kinase pathways in Microglia and THP1 monocytes
    • McDonald DR, Bamberger ME, Combs CK, Landreth GE (1998) b-Amyloid fibrils activate parallel mitogen-Activated protein kinase pathways in Microglia and THP1 monocytes. J Neurosci 18(12):4451-4460
    • (1998) J Neurosci , vol.18 , Issue.12 , pp. 4451-4460
    • McDonald, D.R.1    Bamberger, M.E.2    Combs, C.K.3    Landreth, G.E.4
  • 46
    • 22244449230 scopus 로고    scopus 로고
    • Abnormal long-lasting synaptic plasticity and cognition in mice lacking the mental retardation gene Pak3
    • Meng J, Meng Y, Hanna A, Janus C, Jia Z (2005) Abnormal long-lasting synaptic plasticity and cognition in mice lacking the mental retardation gene Pak3. J Neurosci 25(28):6641-6650
    • (2005) J Neurosci , vol.25 , Issue.28 , pp. 6641-6650
    • Meng, J.1    Meng, Y.2    Hanna, A.3    Janus, C.4    Jia, Z.5
  • 47
    • 33747611218 scopus 로고    scopus 로고
    • Mutational analysis of DJ-1 in Drosophila implicates functional inactivation by oxidative damage and aging
    • Meulener MC, Xu K, Thomson L, Ischiropoulos H, Bonini NM (2006) Mutational analysis of DJ-1 in Drosophila implicates functional inactivation by oxidative damage and aging. PNAS 103(33):12517-12522. doi:10.1073/pnas.0601891103
    • (2006) PNAS , vol.103 , Issue.33 , pp. 12517-12522
    • Meulener, M.C.1    Xu, K.2    Thomson, L.3    Ischiropoulos, H.4    Bonini, N.M.5
  • 48
    • 77953801296 scopus 로고    scopus 로고
    • Genetic determinants at the interface of cancer and neurodegenerative disease
    • Morris LGT, Veeriah S, Chan TA (2010) Genetic determinants at the interface of cancer and neurodegenerative disease. Oncogene 29(24):3453-3464. doi:10.1038/onc.2010.127
    • (2010) Oncogene , vol.29 , Issue.24 , pp. 3453-3464
    • Morris, L.G.T.1    Veeriah, S.2    Chan, T.A.3
  • 51
    • 33947317590 scopus 로고    scopus 로고
    • Conditional neuronal Simian Virus 40 T antigen expression induces Alzheimer-Like Tau and Amyloid pathology in mice
    • Park KHJ, Hallows JL, Chakrabarty P, Davies P, Vincent I (2007) Conditional neuronal Simian Virus 40 T antigen expression induces Alzheimer-Like Tau and Amyloid pathology in mice. J Neurosci 27(11):2969-2978. doi:10.1523/jneurosci.0186-07.2007
    • (2007) J Neurosci , vol.27 , Issue.11 , pp. 2969-2978
    • Park, K.H.J.1    Hallows, J.L.2    Chakrabarty, P.3    Davies, P.4    Vincent, I.5
  • 52
    • 33745163261 scopus 로고    scopus 로고
    • Enhanced sensitivity of DJ-1-deficient dopaminergic neurons to energy metabolism impairment: Role of Na+/K + ATPase
    • Pisani A, Martella G, Tscherter A, Costa C, Mercuri NB, Bernardi G, Shen J, Calabresi P (2006) Enhanced sensitivity of DJ-1-deficient dopaminergic neurons to energy metabolism impairment: role of Na+/K + ATPase. Neurobiol Dis 23(1):54-60. doi:10.1016/j.nbd.2006.02.001
    • (2006) Neurobiol Dis , vol.23 , Issue.1 , pp. 54-60
    • Pisani, A.1    Martella, G.2    Tscherter, A.3    Costa, C.4    Mercuri, N.B.5    Bernardi, G.6    Shen, J.7    Calabresi, P.8
  • 56
    • 79957952408 scopus 로고    scopus 로고
    • Can dietary antioxidants reduce the incidence of brain tumors
    • Sheweita SA, Sheikh BY (2011) Can dietary antioxidants reduce the incidence of brain tumors? Curr Drug Metab 12(6):587-593
    • (2011) Curr Drug Metab , vol.12 , Issue.6 , pp. 587-593
    • Sheweita, S.A.1    Sheikh, B.Y.2
  • 58
    • 84875282051 scopus 로고    scopus 로고
    • Melatonin and synthetic analogs as antioxidants
    • Suzen S (2013) Melatonin and synthetic analogs as antioxidants. Curr Drug Deliv 10(1):71-75
    • (2013) Curr Drug Deliv , vol.10 , Issue.1 , pp. 71-75
    • Suzen, S.1
  • 59
    • 0028295848 scopus 로고
    • Cell cycle-dependent regulation of the phosphorylation and metabolism of the Alzheimer amyloid precursor protein
    • Suzuki T, Oishi M, Marshak DR, Czernik AJ, Nairn AC, Greengard P (1994) Cell cycle-dependent regulation of the phosphorylation and metabolism of the Alzheimer amyloid precursor protein. EMBO J 13(5):1114-1122
    • (1994) EMBO J , vol.13 , Issue.5 , pp. 1114-1122
    • Suzuki, T.1    Oishi, M.2    Marshak, D.R.3    Czernik, A.J.4    Nairn, A.C.5    Greengard, P.6
  • 60
    • 84880283997 scopus 로고    scopus 로고
    • Alzheimer disease and antioxidant therapy: How long how far
    • Teixeira J, Silva T, Andrade PB, Borges F (2013) Alzheimer disease and antioxidant therapy: how long how far? Curr Med Chem 20(24):2939-2952
    • (2013) Curr Med Chem , vol.20 , Issue.24 , pp. 2939-2952
    • Teixeira, J.1    Silva, T.2    Andrade, P.B.3    Borges, F.4
  • 61
    • 37349004102 scopus 로고    scopus 로고
    • Parkinson's disease
    • Thomas B, Beal MF (2007) Parkinson's disease. Hum Mol Genet 16 Spec No. 2:R183-194. doi:10.1093/hmg/ddm159
    • (2007) Hum Mol Genet , vol.16 , Issue.2 , pp. R183-194
    • Thomas, B.1    Beal, M.F.2
  • 64
    • 0031006939 scopus 로고    scopus 로고
    • Aberrant expression of mitotic cdc2/cyclin B1 kinase in degenerating neurons of Alzheimer's disease brain
    • Vincent I, Jicha G, Rosado M, Dickson DW (1997) Aberrant expression of mitotic cdc2/cyclin B1 kinase in degenerating neurons of Alzheimer's disease brain. J Neurosci Off J Soc Neurosci 17(10):3588-3598
    • (1997) J Neurosci off J Soc Neurosci , vol.17 , Issue.10 , pp. 3588-3598
    • Vincent, I.1    Jicha, G.2    Rosado, M.3    Dickson, D.W.4
  • 65
    • 68749118423 scopus 로고    scopus 로고
    • Neural cell cycle dysregulation and central nervous system diseases
    • Wang W, Bu B, Xie M, Zhang M, Yu Z, Tao D (2009) Neural cell cycle dysregulation and central nervous system diseases. Prog Neurobiol 89(1):1-17. doi:10.1016/j.pneurobio.2009.01.007
    • (2009) Prog Neurobiol , vol.89 , Issue.1 , pp. 1-17
    • Wang, W.1    Bu, B.2    Xie, M.3    Zhang, M.4    Yu, Z.5    Tao, D.6
  • 66
    • 48749085779 scopus 로고    scopus 로고
    • Dynamin-like protein 1 reduction underlies mitochondrial morphology and distribution abnormalities in fibroblasts from sporadic Alzheimer's disease patients
    • Wang X, Su B, Fujioka H, Zhu X (2008) Dynamin-like protein 1 reduction underlies mitochondrial morphology and distribution abnormalities in fibroblasts from sporadic Alzheimer's disease patients. Am J Pathol 173(2):470-482. doi:10.2353/ajpath.2008.071208
    • (2008) Am J Pathol , vol.173 , Issue.2 , pp. 470-482
    • Wang, X.1    Su, B.2    Fujioka, H.3    Zhu, X.4
  • 67
    • 0037124108 scopus 로고    scopus 로고
    • Signaling events in amyloid beta-peptide-induced neuronal death and insulin-like growth factor i protection
    • Wei W, Wang X, Kusiak JW (2002) Signaling events in amyloid beta-peptide-induced neuronal death and insulin-like growth factor I protection. J Biol Chem 277(20):17649-17656. doi:10.1074/jbc.M111704200
    • (2002) J Biol Chem , vol.277 , Issue.20 , pp. 17649-17656
    • Wei, W.1    Wang, X.2    Kusiak, J.W.3
  • 68
    • 33947151122 scopus 로고    scopus 로고
    • The cell cycle hypothesis of Alzheimer's disease: Suggestions for drug development
    • Woods J, Snape M, Smith MA (2007) The cell cycle hypothesis of Alzheimer's disease: suggestions for drug development. Biochim Biophys Acta 1772(4):503-508. doi:10.1016/j. bbadis.2006.12.004
    • (2007) Biochim Biophys Acta , vol.1772 , Issue.4 , pp. 503-508
    • Woods, J.1    Snape, M.2    Smith, M.A.3
  • 70
    • 33746355607 scopus 로고    scopus 로고
    • DJ-1 transcriptionally up-regulates the human tyrosine hydroxylase by inhibiting the sumoylation of pyrimidine tract-binding protein-Associated splicing factor
    • Zhong N, Kim CY, Rizzu P, Geula C, Porter DR, Pothos EN, Squitieri F, Heutink P, Xu J (2006) DJ-1 transcriptionally up-regulates the human tyrosine hydroxylase by inhibiting the sumoylation of pyrimidine tract-binding protein-Associated splicing factor. J Biol Chem 281(30):20940-20948. doi:10.1074/jbc.M601935200
    • (2006) J Biol Chem , vol.281 , Issue.30 , pp. 20940-20948
    • Zhong, N.1    Kim, C.Y.2    Rizzu, P.3    Geula, C.4    Porter, D.R.5    Pothos, E.N.6    Squitieri, F.7    Heutink, P.8    Xu, J.9
  • 71
    • 31344464179 scopus 로고    scopus 로고
    • The oxidation state of DJ-1 regulates its chaperone activity toward alpha-synuclein
    • Zhou W, Zhu M, Wilson MA, Petsko GA, Fink AL (2006) The oxidation state of DJ-1 regulates its chaperone activity toward alpha-synuclein. J Mol Biol 356(4):1036-1048. doi:10.1016/j. jmb.2005.12.030
    • (2006) J Mol Biol , vol.356 , Issue.4 , pp. 1036-1048
    • Zhou, W.1    Zhu, M.2    Wilson, M.A.3    Petsko, G.A.4    Fink, A.L.5
  • 72
    • 33947178563 scopus 로고    scopus 로고
    • Alzheimer disease, the two-hit hypothesis: An update
    • Zhu X, H-g L, Perry G, Smith MA (2007) Alzheimer disease, the two-hit hypothesis: an update. Biochim Biophys Acta 1772(4):494-502. doi:10.1016/j.bbadis.2006.10.014
    • (2007) Biochim Biophys Acta , vol.1772 , Issue.4 , pp. 494-502
    • Zhu, X.1    H-G, L.2    Perry, G.3    Smith, M.A.4
  • 73
    • 0035142804 scopus 로고    scopus 로고
    • Activation and redistribution of c-jun N-terminal kinase/stress activated protein kinase in degenerating neurons in Alzheimer's disease
    • Zhu X, Raina AK, Rottkamp CA, Aliev G, Perry G, Boux H, Smith MA (2001) Activation and redistribution of c-jun N-terminal kinase/stress activated protein kinase in degenerating neurons in Alzheimer's disease. J Neurochem 76(2):435-441
    • (2001) J Neurochem , vol.76 , Issue.2 , pp. 435-441
    • Zhu, X.1    Raina, A.K.2    Rottkamp, C.A.3    Aliev, G.4    Perry, G.5    Boux, H.6    Smith, M.A.7
  • 75
    • 33344476774 scopus 로고    scopus 로고
    • PTEN: A crucial mediator of mitochondriadependent apoptosis
    • Zhu Y, Hoell P, Ahlemeyer B, Krieglstein J (2006) PTEN: A crucial mediator of mitochondriadependent apoptosis. Apoptosis 11(2):197-207. doi:10.1007/s10495-006-3714-5
    • (2006) Apoptosis , vol.11 , Issue.2 , pp. 197-207
    • Zhu, Y.1    Hoell, P.2    Ahlemeyer, B.3    Krieglstein, J.4


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