-
1
-
-
20044367108
-
Cell-cycle reentry and cell death in transgenic mice expressing nonmutant human tau isoforms
-
Andorfer, C.; Acker, C.M.; Kress, Y.; Hof, P.R.; Duff, K.; Davies, P. Cell-cycle reentry and cell death in transgenic mice expressing nonmutant human tau isoforms. J. Neurosci., 2005, 25(22), 5446-5454.
-
(2005)
J. Neurosci
, vol.25
, Issue.22
, pp. 5446-5454
-
-
Andorfer, C.1
Acker, C.M.2
Kress, Y.3
Hof, P.R.4
Duff, K.5
Davies, P.6
-
2
-
-
1242341923
-
Incipient Alzheimer's disease: Microarray correlation analyses reveal major transcriptional and tumor suppressor responses
-
Blalock, E.M.; Geddes, J.W.; Chen, K.C.; Porter, N.M.; Markesbery, W.R.; Landfield, P.W. Incipient Alzheimer's disease: microarray correlation analyses reveal major transcriptional and tumor suppressor responses. Proc. Natl. Acad. Sci. USA, 2004, 101(7), 2173-2178.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, Issue.7
, pp. 2173-2178
-
-
Blalock, E.M.1
Geddes, J.W.2
Chen, K.C.3
Porter, N.M.4
Markesbery, W.R.5
Landfield, P.W.6
-
3
-
-
67651089766
-
The p21-activated kinase is required for neuronal migration in the cerebral cortex
-
Causeret, F.; Terao, M.; Jacobs, T.; Nishimura, Y.V.; Yanagawa, Y.; Obata, K.; Hoshino, M.; Nikolic, M. The p21-activated kinase is required for neuronal migration in the cerebral cortex. Cereb. Cortex, 2009, 19(4), 861-875.
-
(2009)
Cereb. Cortex
, vol.19
, Issue.4
, pp. 861-875
-
-
Causeret, F.1
Terao, M.2
Jacobs, T.3
Nishimura, Y.V.4
Yanagawa, Y.5
Obata, K.6
Hoshino, M.7
Nikolic, M.8
-
4
-
-
33745684525
-
p21-activated kinases in cancer
-
Kumar, R.; Gururaj, A.E.; Barnes, C.J. p21-activated kinases in cancer. Nat. Rev. Cancer, 2006, 6(6), 459-471.
-
(2006)
Nat. Rev. Cancer
, vol.6
, Issue.6
, pp. 459-471
-
-
Kumar, R.1
Gururaj, A.E.2
Barnes, C.J.3
-
5
-
-
22244449230
-
Abnormal longlasting synaptic plasticity and cognition in mice lacking the mental retardation gene Pak3
-
Meng, J.; Meng, Y.; Hanna, A.; Janus, C.; Jia, Z. Abnormal longlasting synaptic plasticity and cognition in mice lacking the mental retardation gene Pak3. J. Neurosci., 2005, 25(28), 6641-6650.
-
(2005)
J. Neurosci
, vol.25
, Issue.28
, pp. 6641-6650
-
-
Meng, J.1
Meng, Y.2
Hanna, A.3
Janus, C.4
Jia, Z.5
-
6
-
-
60649083945
-
Cell cycle reentry mediated neurodegeneration and its treatment role in the pathogenesis of Alzheimer's disease
-
Lee, H.G.; Casadesus, G.; Zhu, X.; Castellani, R.J.; McShea, A.; Perry, G.; Petersen, R.B.; Bajic, V.; Smith, M.A. Cell cycle reentry mediated neurodegeneration and its treatment role in the pathogenesis of Alzheimer's disease. Neurochem. Int., 2009, 54(2), 84-88.
-
(2009)
Neurochem. Int
, vol.54
, Issue.2
, pp. 84-88
-
-
Lee, H.G.1
Casadesus, G.2
Zhu, X.3
Castellani, R.J.4
McShea, A.5
Perry, G.6
Petersen, R.B.7
Bajic, V.8
Smith, M.A.9
-
7
-
-
49549083587
-
Neuronal binucleation in Alzheimer disease hippocampus
-
Zhu, X.; Siedlak, S.L.; Wang, Y.; Perry, G.; Castellani, R.J.; Cohen, M.L.; Smith, M.A. Neuronal binucleation in Alzheimer disease hippocampus. Neuropathol. Appl. Neurobiol., 2008, 34(4), 457-465.
-
(2008)
Neuropathol. Appl. Neurobiol
, vol.34
, Issue.4
, pp. 457-465
-
-
Zhu, X.1
Siedlak, S.L.2
Wang, Y.3
Perry, G.4
Castellani, R.J.5
Cohen, M.L.6
Smith, M.A.7
-
8
-
-
33947151122
-
The cell cycle hypothesis of Alzheimer's disease: Suggestions for drug development
-
Woods, J.; Snape, M.; Smith, M.A. The cell cycle hypothesis of Alzheimer's disease: suggestions for drug development. Biochim. Biophys. Acta, 2007, 1772(4), 503-508.
-
(2007)
Biochim. Biophys. Acta
, vol.1772
, Issue.4
, pp. 503-508
-
-
Woods, J.1
Snape, M.2
Smith, M.A.3
-
9
-
-
33947181594
-
Neuronal cell cycle re-entry mediates Alzheimer disease-type changes
-
McShea, A.; Lee, H.G.; Petersen, R.B.; Casadesus, G.; Vincent, I.; Linford, N.J.; Funk, J.O.; Shapiro, R.A.; Smith, M.A. Neuronal cell cycle re-entry mediates Alzheimer disease-type changes. Biochim. Biophys. Acta, 2007, 1772(4), 467-472.
-
(2007)
Biochim. Biophys. Acta
, vol.1772
, Issue.4
, pp. 467-472
-
-
McShea, A.1
Lee, H.G.2
Petersen, R.B.3
Casadesus, G.4
Vincent, I.5
Linford, N.J.6
Funk, J.O.7
Shapiro, R.A.8
Smith, M.A.9
-
10
-
-
33947317590
-
Conditional neuronal simian virus 40 T antigen expression induces Alzheimer-like tau and amyloid pathology in mice
-
Park, K.H.; Hallows, J.L.; Chakrabarty, P.; Davies, P.; Vincent, I. Conditional neuronal simian virus 40 T antigen expression induces Alzheimer-like tau and amyloid pathology in mice. J. Neurosci., 2007, 27(11), 2969-2978.
-
(2007)
J. Neurosci
, vol.27
, Issue.11
, pp. 2969-2978
-
-
Park, K.H.1
Hallows, J.L.2
Chakrabarty, P.3
Davies, P.4
Vincent, I.5
-
11
-
-
0027246336
-
Amyloid precursor protein in peripheral mononuclear cells is up-regulated with cell activation
-
Ledoux, S.; Rebai, N.; Dagenais, A.; Shaw, I.T.; Nalbantoglu, J.; Sekaly, R.P.; Cashman, N.R. Amyloid precursor protein in peripheral mononuclear cells is up-regulated with cell activation. J. Immunol., 1993, 150(12), 5566-5575.
-
(1993)
J. Immunol
, vol.150
, Issue.12
, pp. 5566-5575
-
-
Ledoux, S.1
Rebai, N.2
Dagenais, A.3
Shaw, I.T.4
Nalbantoglu, J.5
Sekaly, R.P.6
Cashman, N.R.7
-
12
-
-
0028295848
-
Cell cycle-dependent regulation of the phosphorylation and metabolism of the Alzheimer amyloid precursor protein
-
Suzuki, T.; Oishi, M.; Marshak, D.R.; Czernik, A.J.; Nairn, A.C.; Greengard, P. Cell cycle-dependent regulation of the phosphorylation and metabolism of the Alzheimer amyloid precursor protein. EMBO J., 1994, 13(5), 1114-1122.
-
(1994)
EMBO J
, vol.13
, Issue.5
, pp. 1114-1122
-
-
Suzuki, T.1
Oishi, M.2
Marshak, D.R.3
Czernik, A.J.4
Nairn, A.C.5
Greengard, P.6
-
13
-
-
0032526423
-
Beta-Amyloid fibrils activate parallel mitogen-activated protein kinase pathways in microglia and THP1 monocytes
-
McDonald, D.R.; Bamberger, M.E.; Combs, C.K.; Landreth, G.E. beta-Amyloid fibrils activate parallel mitogen-activated protein kinase pathways in microglia and THP1 monocytes. J. Neurosci., 1998, 18(12), 4451-4460.
-
(1998)
J. Neurosci
, vol.18
, Issue.12
, pp. 4451-4460
-
-
McDonald, D.R.1
Bamberger, M.E.2
Combs, C.K.3
Landreth, G.E.4
-
14
-
-
0033516567
-
Involvement of cell cycle elements, cyclin-dependent kinases, pRb, and E2F x DP, in B-amyloid-induced neuronal death
-
Giovanni, A.; Wirtz-Brugger, F.; Keramaris, E.; Slack, R.; Park, D.S. Involvement of cell cycle elements, cyclin-dependent kinases, pRb, and E2F x DP, in B-amyloid-induced neuronal death. J. Biol. Chem., 1999, 274(27), 19011-19016.
-
(1999)
J. Biol. Chem
, vol.274
, Issue.27
, pp. 19011-19016
-
-
Giovanni, A.1
Wirtz-Brugger, F.2
Keramaris, E.3
Slack, R.4
Park, D.S.5
-
15
-
-
0031982670
-
Presenilins, the endoplasmic reticulum, and neuronal apoptosis in Alzheimer's disease
-
Mattson, M.P.; Guo, Q.; Furukawa, K.; Pedersen, W.A. Presenilins, the endoplasmic reticulum, and neuronal apoptosis in Alzheimer's disease. J. Neurochem., 1998, 70(1), 1-14.
-
(1998)
J. Neurochem
, vol.70
, Issue.1
, pp. 1-14
-
-
Mattson, M.P.1
Guo, Q.2
Furukawa, K.3
Pedersen, W.A.4
-
16
-
-
41849118025
-
Loss of neuronal cell cycle control as a mechanism of neurodegeneration in the presenilin-1 Alzheimer's disease brain
-
Malik, B.; Currais, A.; Andres, A.; Towlson, C.; Pitsi, D.; Nunes, A.; Niblock, M.; Cooper, J.; Hortobagyi, T.; Soriano, S. Loss of neuronal cell cycle control as a mechanism of neurodegeneration in the presenilin-1 Alzheimer's disease brain. Cell Cycle, 2008, 7(5), 637-646.
-
(2008)
Cell Cycle
, vol.7
, Issue.5
, pp. 637-646
-
-
Malik, B.1
Currais, A.2
Andres, A.3
Towlson, C.4
Pitsi, D.5
Nunes, A.6
Niblock, M.7
Cooper, J.8
Hortobagyi, T.9
Soriano, S.10
-
17
-
-
33749826587
-
p25/cyclin-dependent kinase 5 induces production and intraneuronal accumulation of amyloid beta in vivo
-
Cruz, J.C.; Kim, D.; Moy, L.Y.; Dobbin, M.M.; Sun, X.; Bronson, R.T.; Tsai, L.H. p25/cyclin-dependent kinase 5 induces production and intraneuronal accumulation of amyloid beta in vivo. J. Neurosci., 2006, 26(41), 10536-10541.
-
(2006)
J. Neurosci
, vol.26
, Issue.41
, pp. 10536-10541
-
-
Cruz, J.C.1
Kim, D.2
Moy, L.Y.3
Dobbin, M.M.4
Sun, X.5
Bronson, R.T.6
Tsai, L.H.7
-
18
-
-
58149268892
-
Retinoic acid attenuates beta-amyloid deposition and rescues memory deficits in an Alzheimer's disease transgenic mouse model
-
Ding, Y.; Qiao, A.; Wang, Z.; Goodwin, J.S.; Lee, E.S.; Block, M.L.; Allsbrook, M.; McDonald, M.P.; Fan, G.H. Retinoic acid attenuates beta-amyloid deposition and rescues memory deficits in an Alzheimer's disease transgenic mouse model. J. Neurosci., 2008, 28(45), 11622-11634.
-
(2008)
J. Neurosci
, vol.28
, Issue.45
, pp. 11622-11634
-
-
Ding, Y.1
Qiao, A.2
Wang, Z.3
Goodwin, J.S.4
Lee, E.S.5
Block, M.L.6
Allsbrook, M.7
McDonald, M.P.8
Fan, G.H.9
-
19
-
-
0037443779
-
Tumor suppressor gene BRCA-1 is expressed by embryonic and adult neural stem cells and involved in cell proliferation
-
Korhonen, L.; Brännvall, K.; Skoglösa, Y.; Lindholm, D. Tumor suppressor gene BRCA-1 is expressed by embryonic and adult neural stem cells and involved in cell proliferation. J. Neurosci. Res., 2003, 71(6), 769-776.
-
(2003)
J. Neurosci. Res
, vol.71
, Issue.6
, pp. 769-776
-
-
Korhonen, L.1
Brännvall, K.2
Skoglösa, Y.3
Lindholm, D.4
-
20
-
-
0034661784
-
Cyclin' toward dementia: Cell cycle abnormalities and abortive oncogenesis in Alzheimer disease
-
Raina, A.K.; Zhu, X.; Rottkamp, C.A.; Monteiro, M.; Takeda, A.; Smith, M.A. Cyclin' toward dementia: cell cycle abnormalities and abortive oncogenesis in Alzheimer disease. J. Neurosci. Res., 2000, 61(2), 128-133.
-
(2000)
J. Neurosci. Res
, vol.61
, Issue.2
, pp. 128-133
-
-
Raina, A.K.1
Zhu, X.2
Rottkamp, C.A.3
Monteiro, M.4
Takeda, A.5
Smith, M.A.6
-
21
-
-
33644750447
-
A role for Brca1 in chromosome end maintenance
-
McPherson, J.P.; Hande, M.P.; Poonepalli, A.; Lemmers, B.; Zablocki, E.; Migon, E.; Shehabeldin, A.; Porras, A.; Karaskova, J.; Vukovic, B.; Squire, J.; Hakem, R. A role for Brca1 in chromosome end maintenance. Hum. Mol. Genet., 2006, 15(6), 831-838.
-
(2006)
Hum. Mol. Genet
, vol.15
, Issue.6
, pp. 831-838
-
-
McPherson, J.P.1
Hande, M.P.2
Poonepalli, A.3
Lemmers, B.4
Zablocki, E.5
Migon, E.6
Shehabeldin, A.7
Porras, A.8
Karaskova, J.9
Vukovic, B.10
Squire, J.11
Hakem, R.12
-
22
-
-
33744931650
-
Telomeres and telomerase in Alzheimer's disease: Epiphenomena or a new focus for therapeutic strategy?
-
Franco, S.; Blasco, M.A.; Siedlak, S.L.; Harris, P.L.; Moreira, P.I.; Perry, G.; Smith, M.A. Telomeres and telomerase in Alzheimer's disease: epiphenomena or a new focus for therapeutic strategy? Alzheimers Dement., 2006, 2(3), 164-168.
-
(2006)
Alzheimers Dement
, vol.2
, Issue.3
, pp. 164-168
-
-
Franco, S.1
Blasco, M.A.2
Siedlak, S.L.3
Harris, P.L.4
Moreira, P.I.5
Perry, G.6
Smith, M.A.7
-
23
-
-
34248345577
-
BRCA1 may modulate neuronal cell cycle re-entry in Alzheimer disease
-
Evans, T.A.; Raina, A.K.; Delacourte, A.; Aprelikova, O.; Lee, H.G.; Zhu, X.; Perry, G.; Smith, M.A. BRCA1 may modulate neuronal cell cycle re-entry in Alzheimer disease. Int. J. Med. Sci., 2007, 4(3), 140-145.
-
(2007)
Int. J. Med. Sci
, vol.4
, Issue.3
, pp. 140-145
-
-
Evans, T.A.1
Raina, A.K.2
Delacourte, A.3
Aprelikova, O.4
Lee, H.G.5
Zhu, X.6
Perry, G.7
Smith, M.A.8
-
24
-
-
33750052885
-
DJ-1, a cancer- and Parkinson's disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2
-
Clements, C.M.; McNally, R.S.; Conti, B.J.; Mak, T.W.; Ting, J.P. DJ-1, a cancer- and Parkinson's disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2. Proc. Natl. Acad. Sci. USA, 2006, 103(41), 15091-15096.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, Issue.41
, pp. 15091-15096
-
-
Clements, C.M.1
McNally, R.S.2
Conti, B.J.3
Mak, T.W.4
Ting, J.P.5
-
25
-
-
33644778845
-
Parkin enhances mitochondrial biogenesis in proliferating cells
-
Kuroda, Y.; Mitsui, T.; Kunishige, M.; Shono, M.; Akaike, M.; Azuma, H.; Matsumoto, T. Parkin enhances mitochondrial biogenesis in proliferating cells. Hum. Mol. Genet., 2006, 15(6), 883-895.
-
(2006)
Hum. Mol. Genet
, vol.15
, Issue.6
, pp. 883-895
-
-
Kuroda, Y.1
Mitsui, T.2
Kunishige, M.3
Shono, M.4
Akaike, M.5
Azuma, H.6
Matsumoto, T.7
-
26
-
-
20144389422
-
Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine(MPTP) and oxidative stress
-
Kim, R.H.; Smith, P.D.; Aleyasin, H.; Hayley, S.; Mount, M.P.; Pownall, S.; Wakeham, A.; You-Ten, A.J.; Kalia, S.K.; Horne, P.; Westaway, D.; Lozano, A.M.; Anisman, H.; Park, D.S.; Mak, T.W. Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine(MPTP) and oxidative stress. Proc. Natl. Acad. Sci. USA, 2005, 102(14), 5215-5220.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, Issue.14
, pp. 5215-5220
-
-
Kim, R.H.1
Smith, P.D.2
Aleyasin, H.3
Hayley, S.4
Mount, M.P.5
Pownall, S.6
Wakeham, A.7
You-Ten, A.J.8
Kalia, S.K.9
Horne, P.10
Westaway, D.11
Lozano, A.M.12
Anisman, H.13
Park, D.S.14
Mak, T.W.15
-
27
-
-
33747611218
-
Mutational analysis of DJ-1 in Drosophila implicates functional inactivation by oxidative damage and aging
-
Meulener, M.C.; Xu, K.; Thomson, L.; Ischiropoulos, H.; Bonini, N.M. Mutational analysis of DJ-1 in Drosophila implicates functional inactivation by oxidative damage and aging. Proc. Natl. Acad. Sci. USA, 2006, 103(33), 12517-12522.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, Issue.33
, pp. 12517-12522
-
-
Meulener, M.C.1
Xu, K.2
Thomson, L.3
Ischiropoulos, H.4
Bonini, N.M.5
-
28
-
-
77449156069
-
Loss of function of DJ-1 triggered by Parkinson's disease-associated mutation is due to proteolytic resistance to caspase-6
-
Giaime, E.; Sunyach, C.; Druon, C.; Scarzello, S.; Robert, G.; Grosso, S.; Auberger, P.; Goldberg, M.S.; Shen, J.; Heutink, P.; Pouyssegur, J.; Pages, G.; Checler, F.; Alves da Costa, C. Loss of function of DJ-1 triggered by Parkinson's disease-associated mutation is due to proteolytic resistance to caspase-6. Cell Death Differ., 2010, 17(1), 158-169.
-
(2010)
Cell Death Differ
, vol.17
, Issue.1
, pp. 158-169
-
-
Giaime, E.1
Sunyach, C.2
Druon, C.3
Scarzello, S.4
Robert, G.5
Grosso, S.6
Auberger, P.7
Goldberg, M.S.8
Shen, J.9
Heutink, P.10
Pouyssegur, J.11
Pages, G.12
Checler, F.13
da Costa, A.C.14
-
29
-
-
1842740232
-
Cysteine-106 of DJ-1 is the most sensitive cysteine residue to hydrogen peroxidemediated oxidation in vivo in human umbilical vein endothelial cells
-
Kinumi, T.; Kimata, J.; Taira, T.; Ariga, H.; Niki, E. Cysteine-106 of DJ-1 is the most sensitive cysteine residue to hydrogen peroxidemediated oxidation in vivo in human umbilical vein endothelial cells. Biochem. Biophys. Res. Commun., 2004, 317(3), 722-728.
-
(2004)
Biochem. Biophys. Res. Commun
, vol.317
, Issue.3
, pp. 722-728
-
-
Kinumi, T.1
Kimata, J.2
Taira, T.3
Ariga, H.4
Niki, E.5
-
30
-
-
33748765225
-
PARK7 DJ-1 protects against degeneration of nigral dopaminergic neurons in Parkinson's disease rat model
-
Inden, M.; Taira, T.; Kitamura, Y.; Yanagida, T.; Tsuchiya, D.; Takata, K.; Yanagisawa, D.; Nishimura, K.; Taniguchi, T.; Kiso, Y.; Yoshimoto, K.; Agatsuma, T.; Koide-Yoshida, S.; Iguchi-Ariga, S.M.; Shimohama, S.; Ariga, H. PARK7 DJ-1 protects against degeneration of nigral dopaminergic neurons in Parkinson's disease rat model. Neurobiol. Dis., 2006, 24(1), 144-158.
-
(2006)
Neurobiol. Dis
, vol.24
, Issue.1
, pp. 144-158
-
-
Inden, M.1
Taira, T.2
Kitamura, Y.3
Yanagida, T.4
Tsuchiya, D.5
Takata, K.6
Yanagisawa, D.7
Nishimura, K.8
Taniguchi, T.9
Kiso, Y.10
Yoshimoto, K.11
Agatsuma, T.12
Koide-Yoshida, S.13
Iguchi-Ariga, S.M.14
Shimohama, S.15
Ariga, H.16
-
31
-
-
31344464179
-
The oxidation state of DJ-1 regulates its chaperone activity toward alpha-synuclein
-
Zhou, W.; Zhu, M.; Wilson, M.A.; Petsko, G.A.; Fink, A.L. The oxidation state of DJ-1 regulates its chaperone activity toward alpha-synuclein. J. Mol. Biol., 2006, 356(4), 1036-1048.
-
(2006)
J. Mol. Biol
, vol.356
, Issue.4
, pp. 1036-1048
-
-
Zhou, W.1
Zhu, M.2
Wilson, M.A.3
Petsko, G.A.4
Fink, A.L.5
-
32
-
-
59049105937
-
DJ-1/PARK7 is an important mediator of hypoxiainduced cellular responses
-
Vasseur, S.; Afzal, S.; Tardivel-Lacombe, J.; Park, D.S.; Iovanna, J.L.; Mak, T.W. DJ-1/PARK7 is an important mediator of hypoxiainduced cellular responses. Proc. Natl. Acad. Sci. USA, 2009, 106(4), 1111-1116.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, Issue.4
, pp. 1111-1116
-
-
Vasseur, S.1
Afzal, S.2
Tardivel-Lacombe, J.3
Park, D.S.4
Iovanna, J.L.5
Mak, T.W.6
-
33
-
-
34250361915
-
Structural determinants of the C-terminal helix-kink-helix motif essential for protein stability and survival promoting activity of DJ-1
-
Gorner, K.; Holtorf, E.; Waak, J.; Pham, T.T.; Vogt-Weisenhorn, D.M.; Wurst, W.; Haass, C.; Kahle, P.J. Structural determinants of the C-terminal helix-kink-helix motif essential for protein stability and survival promoting activity of DJ-1. J. Biol. Chem., 2007, 282(18), 13680-13691.
-
(2007)
J. Biol. Chem
, vol.282
, Issue.18
, pp. 13680-13691
-
-
Gorner, K.1
Holtorf, E.2
Waak, J.3
Pham, T.T.4
Vogt-Weisenhorn, D.M.5
Wurst, W.6
Haass, C.7
Kahle, P.J.8
-
34
-
-
33847723997
-
p53-dependent neuronal cell death in a DJ-1-deficient zebrafish model of Parkinson's disease
-
Bretaud, S.; Allen, C.; Ingham, P.W.; Bandmann, O. p53-dependent neuronal cell death in a DJ-1-deficient zebrafish model of Parkinson's disease. J. Neurochem., 2007, 100(6), 1626-1635.
-
(2007)
J. Neurochem
, vol.100
, Issue.6
, pp. 1626-1635
-
-
Bretaud, S.1
Allen, C.2
Ingham, P.W.3
Bandmann, O.4
-
35
-
-
33745163261
-
Enhanced sensitivity of DJ-1-deficient dopaminergic neurons to energy metabolism impairment: Role of Na+/K+ ATPase
-
Pisani, A.; Martella, G.; Tscherter, A.; Costa, C.; Mercuri, N.B.; Bernardi, G.; Shen, J.; Calabresi, P. Enhanced sensitivity of DJ-1-deficient dopaminergic neurons to energy metabolism impairment: role of Na+/K+ ATPase. Neurobiol. Dis., 2006, 23(1), 54-60.
-
(2006)
Neurobiol. Dis
, vol.23
, Issue.1
, pp. 54-60
-
-
Pisani, A.1
Martella, G.2
Tscherter, A.3
Costa, C.4
Mercuri, N.B.5
Bernardi, G.6
Shen, J.7
Calabresi, P.8
-
36
-
-
26444489693
-
Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling
-
Yang, Y.; Gehrke, S.; Haque, M.E.; Imai, Y.; Kosek, J.; Yang, L.; Beal, M.F.; Nishimura, I.; Wakamatsu, K.; Ito, S.; Takahashi, R.; Lu, B. Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling. Proc. Natl. Acad. Sci. USA, 2005, 102(38), 13670-13675.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, Issue.38
, pp. 13670-13675
-
-
Yang, Y.1
Gehrke, S.2
Haque, M.E.3
Imai, Y.4
Kosek, J.5
Yang, L.6
Beal, M.F.7
Nishimura, I.8
Wakamatsu, K.9
Ito, S.10
Takahashi, R.11
Lu, B.12
-
37
-
-
22144465488
-
Interaction of dj-1 with daxx inhibits apoptosis signal-regulating kinase 1 activity and cell death
-
Junn, E.; Taniguchi, H.; Jeong, B.S.; Zhao, X.; Ichijo, H.; Mouradian, M.M. Interaction of DJ-1 with Daxx inhibits apoptosis signal-regulating kinase 1 activity and cell death. Proc. Natl. Acad. Sci. USA, 2005, 102(27), 9691-9696.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, Issue.27
, pp. 9691-9696
-
-
Junn, E.1
Taniguchi, H.2
Jeong, B.S.3
Zhao, X.4
Ichijo, H.5
Mouradian, M.M.6
-
38
-
-
33746355607
-
DJ-1 transcriptionally upregulates the human tyrosine hydroxylase by inhibiting the sumoylation of pyrimidine tract-binding protein-associated splicing factor
-
Zhong, N.; Kim, C.Y.; Rizzu, P.; Geula, C.; Porter, D.R.; Pothos, E.N.; Squitieri, F.; Heutink, P.; Xu, J. DJ-1 transcriptionally upregulates the human tyrosine hydroxylase by inhibiting the sumoylation of pyrimidine tract-binding protein-associated splicing factor. J. Biol. Chem., 2006, 281(30), 20940-20948.
-
(2006)
J. Biol. Chem
, vol.281
, Issue.30
, pp. 20940-20948
-
-
Zhong, N.1
Kim, C.Y.2
Rizzu, P.3
Geula, C.4
Porter, D.R.5
Pothos, E.N.6
Squitieri, F.7
Heutink, P.8
Xu, J.9
-
39
-
-
33644513730
-
Beyond PTEN mutations: The PI3K pathway as an integrator of multiple inputs during tumorigenesis
-
Cully, M.; You, H.; Levine, A.J.; Mak, T.W. Beyond PTEN mutations: the PI3K pathway as an integrator of multiple inputs during tumorigenesis. Nat. Rev. Cancer, 2006, 6(3), 184-192.
-
(2006)
Nat. Rev. Cancer
, vol.6
, Issue.3
, pp. 184-192
-
-
Cully, M.1
You, H.2
Levine, A.J.3
Mak, T.W.4
-
40
-
-
77953801296
-
Genetic determinants at the interface of cancer and neurodegenerative disease
-
Morris, L.G.; Veeriah, S.; Chan, T.A. Genetic determinants at the interface of cancer and neurodegenerative disease. Oncogene, 2010, 29(24), 3453-3464.
-
(2010)
Oncogene
, vol.29
, Issue.24
, pp. 3453-3464
-
-
Morris, L.G.1
Veeriah, S.2
Chan, T.A.3
-
41
-
-
33344476774
-
PTEN: A crucial mediator of mitochondria-dependent apoptosis
-
Zhu, Y.; Hoell, P.; Ahlemeyer, B.; Krieglstein, J. PTEN: a crucial mediator of mitochondria-dependent apoptosis. Apoptosis, 2006, 11(2), 197-207.
-
(2006)
Apoptosis
, vol.11
, Issue.2
, pp. 197-207
-
-
Zhu, Y.1
Hoell, P.2
Ahlemeyer, B.3
Krieglstein, J.4
-
42
-
-
0034912744
-
PTEN and myotubularin: Novel phosphoinositide phosphatases
-
Maehama, T.; Taylor, G.S.; Dixon, J.E. PTEN and myotubularin: novel phosphoinositide phosphatases. Annu. Rev. Biochem., 2001, 70, 247-279.
-
(2001)
Annu. Rev. Biochem
, vol.70
, pp. 247-279
-
-
Maehama, T.1
Taylor, G.S.2
Dixon, J.E.3
-
43
-
-
34250190649
-
Inhibition of PTEN by peroxynitrite activates the phosphoinositide-3-kinase/Akt neuroprotective signaling pathway
-
Delgado-Esteban, M.; Martin-Zanca, D.; Andres-Martin, L.; Almeida, A.; Bolanos, J.P. Inhibition of PTEN by peroxynitrite activates the phosphoinositide-3-kinase/Akt neuroprotective signaling pathway. J. Neurochem., 2007, 102(1), 194-205.
-
(2007)
J. Neurochem
, vol.102
, Issue.1
, pp. 194-205
-
-
Delgado-Esteban, M.1
Martin-Zanca, D.2
Andres-Martin, L.3
Almeida, A.4
Bolanos, J.P.5
-
44
-
-
33644834046
-
Tumours and tremors: How PTEN regulation underlies both
-
Kim, R.H.; Mak, T.W. Tumours and tremors: how PTEN regulation underlies both. Br. J. Cancer, 2006, 94(5), 620-624.
-
(2006)
Br. J. Cancer
, vol.94
, Issue.5
, pp. 620-624
-
-
Kim, R.H.1
Mak, T.W.2
-
45
-
-
49649097747
-
Loss of PINK1 causes mitochondrial functional defects and increased sensitivity to oxidative stress
-
Gautier, C.A.; Kitada, T.; Shen, J. Loss of PINK1 causes mitochondrial functional defects and increased sensitivity to oxidative stress. Proc. Natl. Acad. Sci. USA, 2008, 105(32), 11364-11369.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, Issue.32
, pp. 11364-11369
-
-
Gautier, C.A.1
Kitada, T.2
Shen, J.3
-
46
-
-
0037124108
-
Signaling events in amyloid betapeptide- induced neuronal death and insulin-like growth factor I protection
-
Wei, W.; Wang, X.; Kusiak, J.W. Signaling events in amyloid betapeptide- induced neuronal death and insulin-like growth factor I protection. J. Biol. Chem., 2002, 277(20), 17649-17656.
-
(2002)
J. Biol. Chem
, vol.277
, Issue.20
, pp. 17649-17656
-
-
Wei, W.1
Wang, X.2
Kusiak, J.W.3
-
47
-
-
33845507061
-
Oncoprotein Akt/PKB induces trophic effects in murine models of Parkinson's disease
-
Ries, V.; Henchcliffe, C.; Kareva, T.; Rzhetskaya, M.; Bland, R.; During, M.J.; Kholodilov, N.; Burke, R.E. Oncoprotein Akt/PKB induces trophic effects in murine models of Parkinson's disease. Proc. Natl. Acad. Sci. USA, 2006, 103(49), 18757-18762.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, Issue.49
, pp. 18757-18762
-
-
Ries, V.1
Henchcliffe, C.2
Kareva, T.3
Rzhetskaya, M.4
Bland, R.5
During, M.J.6
Kholodilov, N.7
Burke, R.E.8
-
48
-
-
37349004102
-
Parkinson's disease
-
Thomas, B.; Beal, M.F. Parkinson's disease. Hum. Mol. Genet., 2007, 16(Spec No.2), R183-R194.
-
(2007)
Hum. Mol. Genet
, vol.16
, Issue.Spec No.2
-
-
Thomas, B.1
Beal, M.F.2
-
49
-
-
33746594215
-
A regulated interaction with the UIM protein Eps15 implicates parkin in EGF receptor trafficking and PI(3)KAkt signalling
-
Fallon, L.; Belanger, C.M.; Corera, A.T.; Kontogiannea, M.; Regan-Klapisz, E.; Moreau, F.; Voortman, J.; Haber, M.; Rouleau, G.; Thorarinsdottir, T.; Brice, A.; van Bergen En Henegouwen, P.M.; Fon, E.A. A regulated interaction with the UIM protein Eps15 implicates parkin in EGF receptor trafficking and PI(3)KAkt signalling. Nat. Cell Biol., 2006, 8(8), 834-842.
-
(2006)
Nat. Cell Biol
, vol.8
, Issue.8
, pp. 834-842
-
-
Fallon, L.1
Belanger, C.M.2
Corera, A.T.3
Kontogiannea, M.4
Regan-Klapisz, E.5
Moreau, F.6
Voortman, J.7
Haber, M.8
Rouleau, G.9
Thorarinsdottir, T.10
Brice, A.11
van Bergen, H.P.M.12
Fon, E.A.13
-
50
-
-
2442668926
-
Hereditary early-onset Parkinson's disease caused by mutations in PINK1
-
Valente, E.M.; Abou-Sleiman, P.M.; Caputo, V.; Muqit, M.M.; Harvey, K.; Gispert, S.; Ali, Z.; Del Turco, D.; Bentivoglio, A.R.; Healy, D.G.; Albanese, A.; Nussbaum, R.; Gonzalez-Maldonado, R.; Deller, T.; Salvi, S.; Cortelli, P.; Gilks, W.P.; Latchman, D.S.; Harvey, R.J.; Dallapiccola, B.; Auburger, G.; Wood, N.W. Hereditary early-onset Parkinson's disease caused by mutations in PINK1. Science, 2004, 304(5674), 1158-160.
-
(2004)
Science
, vol.304
, Issue.5674
, pp. 1158-1160
-
-
Valente, E.M.1
Abou-Sleiman, P.M.2
Caputo, V.3
Muqit, M.M.4
Harvey, K.5
Gispert, S.6
Ali, Z.7
del Turco, D.8
Bentivoglio, A.R.9
Healy, D.G.10
Albanese, A.11
Nussbaum, R.12
Gonzalez-Maldonado, R.13
Deller, T.14
Salvi, S.15
Cortelli, P.16
Gilks, W.P.17
Latchman, D.S.18
Harvey, R.J.19
Dallapiccola, B.20
Auburger, G.21
Wood, N.W.22
more..
-
51
-
-
0037726598
-
Interaction of Akt-phosphorylated ataxin-1 with 14-3-3 mediates neurodegeneration in spinocerebellar ataxia type 1
-
Chen, H.K.; Fernandez-Funez, P.; Acevedo, S.F.; Lam, Y.C.; Kaytor, M.D.; Fernandez, M.H.; Aitken, A.; Skoulakis, E.M.; Orr, H.T.; Botas, J.; Zoghbi, H.Y. Interaction of Akt-phosphorylated ataxin-1 with 14-3-3 mediates neurodegeneration in spinocerebellar ataxia type 1. Cell, 2003, 113(4), 457-468.
-
(2003)
Cell
, vol.113
, Issue.4
, pp. 457-468
-
-
Chen, H.K.1
Fernandez-Funez, P.2
Acevedo, S.F.3
Lam, Y.C.4
Kaytor, M.D.5
Fernandez, M.H.6
Aitken, A.7
Skoulakis, E.M.8
Orr, H.T.9
Botas, J.10
Zoghbi, H.Y.11
-
52
-
-
29244482770
-
PTEN levels in Alzheimer's disease medial temporal cortex
-
Rickle, A.; Bogdanovic, N.; Volkmann, I.; Zhou, X.; Pei, J.J.; Winblad, B.; Cowburn, R.F. PTEN levels in Alzheimer's disease medial temporal cortex. Neurochem. Int., 2006, 48(2), 114-123.
-
(2006)
Neurochem. Int
, vol.48
, Issue.2
, pp. 114-123
-
-
Rickle, A.1
Bogdanovic, N.2
Volkmann, I.3
Zhou, X.4
Pei, J.J.5
Winblad, B.6
Cowburn, R.F.7
-
53
-
-
16244391770
-
Activation of Akt/PKB, increased phosphorylation of Akt substrates and loss and altered distribution of Akt and PTEN are features of Alzheimer's disease pathology
-
Griffin, R.J.; Moloney, A.; Kelliher, M.; Johnston, J.A.; Ravid, R.; Dockery, P.; O'Connor, R.; O'Neill, C. Activation of Akt/PKB, increased phosphorylation of Akt substrates and loss and altered distribution of Akt and PTEN are features of Alzheimer's disease pathology. J. Neurochem., 2005, 93(1), 105-117.
-
(2005)
J. Neurochem
, vol.93
, Issue.1
, pp. 105-117
-
-
Griffin, R.J.1
Moloney, A.2
Kelliher, M.3
Johnston, J.A.4
Ravid, R.5
Dockery, P.6
O'Connor, R.7
O'Neill, C.8
-
54
-
-
58249089343
-
Agedependent deterioration of nuclear pore complexes causes a loss of nuclear integrity in postmitotic cells
-
D'Angelo, M.A.; Raices, M.; Panowski, S.H.; Hetzer, M.W. Agedependent deterioration of nuclear pore complexes causes a loss of nuclear integrity in postmitotic cells. Cell, 2009, 136(2), 284-295.
-
(2009)
Cell
, vol.136
, Issue.2
, pp. 284-295
-
-
D'Angelo, M.A.1
Raices, M.2
Panowski, S.H.3
Hetzer, M.W.4
-
55
-
-
58249089339
-
Old nuclei spring new leaks
-
Kotwaliwale, C.V.; Dernburg, A.F. Old nuclei spring new leaks. Cell, 2009, 136(2), 211-212.
-
(2009)
Cell
, vol.136
, Issue.2
, pp. 211-212
-
-
Kotwaliwale, C.V.1
Dernburg, A.F.2
-
56
-
-
73849122773
-
Oxidative stress inhibits nuclear protein export by multiple mechanisms that target FG nucleoporins and Crm1
-
Crampton, N.; Kodiha, M.; Shrivastava, S.; Umar, R.; Stochaj, U. Oxidative stress inhibits nuclear protein export by multiple mechanisms that target FG nucleoporins and Crm1. Mol. Biol. Cell, 2009, 20(24), 5106-5116.
-
(2009)
Mol. Biol. Cell
, vol.20
, Issue.24
, pp. 5106-5116
-
-
Crampton, N.1
Kodiha, M.2
Shrivastava, S.3
Umar, R.4
Stochaj, U.5
-
57
-
-
33947178563
-
Alzheimer disease, the two-hit hypothesis: An update
-
Zhu, X.; Lee, H.G.; Perry, G.; Smith, M.A. Alzheimer disease, the two-hit hypothesis: an update. Biochim. Biophys. Acta, 2007, 1772(4), 494-502.
-
(2007)
Biochim. Biophys. Acta
, vol.1772
, Issue.4
, pp. 494-502
-
-
Zhu, X.1
Lee, H.G.2
Perry, G.3
Smith, M.A.4
-
58
-
-
68749118423
-
Neural cell cycle dysregulation and central nervous system diseases
-
Wang, W.; Bu, B.; Xie, M.; Zhang, M.; Yu, Z.; Tao, D. Neural cell cycle dysregulation and central nervous system diseases. Prog. Neurobiol., 2009, 89(1), 1-17.
-
(2009)
Prog. Neurobiol
, vol.89
, Issue.1
, pp. 1-17
-
-
Wang, W.1
Bu, B.2
Xie, M.3
Zhang, M.4
Yu, Z.5
Tao, D.6
-
59
-
-
0037366104
-
Oxidative stress, cell cycle, and neurodegeneration
-
Klein, J.A.; Ackerman, S.L. Oxidative stress, cell cycle, and neurodegeneration. J. Clin. Invest., 2003, 111(6), 785-793.
-
(2003)
J. Clin. Invest
, vol.111
, Issue.6
, pp. 785-793
-
-
Klein, J.A.1
Ackerman, S.L.2
-
60
-
-
0031006939
-
Aberrant expression of mitotic cdc2/cyclin B1 kinase in degenerating neurons of Alzheimer's disease brain
-
Vincent, I.; Jicha, G.; Rosado, M.; Dickson, D.W. Aberrant expression of mitotic cdc2/cyclin B1 kinase in degenerating neurons of Alzheimer's disease brain. J. Neurosci., 1997, 17(10), 3588-3598.
-
(1997)
J. Neurosci
, vol.17
, Issue.10
, pp. 3588-3598
-
-
Vincent, I.1
Jicha, G.2
Rosado, M.3
Dickson, D.W.4
-
61
-
-
77949897817
-
Review: Cell cycle aberrations and neurodegeneration
-
Bonda, D.J.; Bajic, V.P.; Spremo-Potparevic, B.; Casadesus, G.; Zhu, X.; Smith, M.A.; Lee, H.G. Review: cell cycle aberrations and neurodegeneration. Neuropathol. Appl. Neurobiol., 2010, 36(2), 157-163.
-
(2010)
Neuropathol. Appl. Neurobiol
, vol.36
, Issue.2
, pp. 157-163
-
-
Bonda, D.J.1
Bajic, V.P.2
Spremo-Potparevic, B.3
Casadesus, G.4
Zhu, X.5
Smith, M.A.6
Lee, H.G.7
-
62
-
-
0036282745
-
Cdc2 phosphorylation of BAD links the cell cycle to the cell death machinery
-
Konishi, Y.; Lehtinen, M.; Donovan, N.; Bonni, A. Cdc2 phosphorylation of BAD links the cell cycle to the cell death machinery. Mol. Cell, 2002, 9(5), 1005-1016.
-
(2002)
Mol. Cell
, vol.9
, Issue.5
, pp. 1005-1016
-
-
Konishi, Y.1
Lehtinen, M.2
Donovan, N.3
Bonni, A.4
-
63
-
-
48749085779
-
Dynamin-like protein 1 reduction underlies mitochondrial morphology and distribution abnormalities in fibroblasts from sporadic Alzheimer's disease patients
-
Wang, X.; Su, B.; Fujioka, H.; Zhu, X. Dynamin-like protein 1 reduction underlies mitochondrial morphology and distribution abnormalities in fibroblasts from sporadic Alzheimer's disease patients. Am. J. Pathol., 2008, 173(2), 470-482.
-
(2008)
Am. J. Pathol
, vol.173
, Issue.2
, pp. 470-482
-
-
Wang, X.1
Su, B.2
Fujioka, H.3
Zhu, X.4
-
64
-
-
0034923434
-
Oxidative damage is the earliest event in Alzheimer disease
-
Nunomura, A.; Perry, G.; Aliev, G.; Hirai, K.; Takeda, A.; Balraj, E.K.; Jones, P.K.; Ghanbari, H.; Wataya, T.; Shimohama, S.; Chiba, S.; Atwood, C.S.; Petersen, R.B.; Smith, M.A. Oxidative damage is the earliest event in Alzheimer disease. J. Neuropathol. Exp. Neurol., 2001, 60(8), 759-767.
-
(2001)
J. Neuropathol. Exp. Neurol
, vol.60
, Issue.8
, pp. 759-767
-
-
Nunomura, A.1
Perry, G.2
Aliev, G.3
Hirai, K.4
Takeda, A.5
Balraj, E.K.6
Jones, P.K.7
Ghanbari, H.8
Wataya, T.9
Shimohama, S.10
Chiba, S.11
Atwood, C.S.12
Petersen, R.B.13
Smith, M.A.14
-
65
-
-
0035341254
-
Mitochondrial abnormalities in Alzheimer's disease
-
Hirai, K.; Aliev, G.; Nunomura, A.; Fujioka, H.; Russell, R.L.; Atwood, C.S.; Johnson, A.B.; Kress, Y.; Vinters, H.V.; Tabaton, M.; Shimohama, S.; Cash, A.D.; Siedlak, S.L.; Harris, P.L.; Jones, P.K.; Petersen, R.B.; Perry, G.; Smith, M.A. Mitochondrial abnormalities in Alzheimer's disease. J. Neurosci., 2001, 21(9), 3017-3023.
-
(2001)
J. Neurosci
, vol.21
, Issue.9
, pp. 3017-3023
-
-
Hirai, K.1
Aliev, G.2
Nunomura, A.3
Fujioka, H.4
Russell, R.L.5
Atwood, C.S.6
Johnson, A.B.7
Kress, Y.8
Vinters, H.V.9
Tabaton, M.10
Shimohama, S.11
Cash, A.D.12
Siedlak, S.L.13
Harris, P.L.14
Jones, P.K.15
Petersen, R.B.16
Perry, G.17
Smith, M.A.18
-
66
-
-
0035142804
-
Activation and redistribution of c-jun N-terminal kinase/stress activated protein kinase in degenerating neurons in Alzheimer's disease
-
Zhu, X.; Raina, A.K.; Rottkamp, C.A.; Aliev, G.; Perry, G.; Boux, H.; Smith, M.A. Activation and redistribution of c-jun N-terminal kinase/stress activated protein kinase in degenerating neurons in Alzheimer's disease. J. Neurochem., 2001, 76(2), 435-441.
-
(2001)
J. Neurochem
, vol.76
, Issue.2
, pp. 435-441
-
-
Zhu, X.1
Raina, A.K.2
Rottkamp, C.A.3
Aliev, G.4
Perry, G.5
Boux, H.6
Smith, M.A.7
|