메뉴 건너뛰기




Volumn 136, Issue 2, 2009, Pages 284-295

Age-Dependent Deterioration of Nuclear Pore Complexes Causes a Loss of Nuclear Integrity in Postmitotic Cells

Author keywords

CELLBIO; DEVBIO; HUMDISEASE

Indexed keywords

CYTOPLASM PROTEIN; NUCLEOPORIN; PROTEIN NUP107; PROTEIN NUP153; PROTEIN NUP160; PROTEIN NUP50; SCAFFOLD PROTEIN; UNCLASSIFIED DRUG;

EID: 58249089343     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cell.2008.11.037     Document Type: Article
Times cited : (442)

References (45)
  • 1
    • 0242585476 scopus 로고    scopus 로고
    • Asymmetric inheritance of oxidatively damaged proteins during cytokinesis
    • Aguilaniu H., Gustafsson L., Rigoulet M., and Nystrom T. Asymmetric inheritance of oxidatively damaged proteins during cytokinesis. Science 299 (2003) 1751-1753
    • (2003) Science , vol.299 , pp. 1751-1753
    • Aguilaniu, H.1    Gustafsson, L.2    Rigoulet, M.3    Nystrom, T.4
  • 3
    • 11344290169 scopus 로고    scopus 로고
    • The integral membrane nucleoporin pom121 functionally links nuclear pore complex assembly and nuclear envelope formation
    • Antonin W., Franz C., Haselmann U., Antony C., and Mattaj I.W. The integral membrane nucleoporin pom121 functionally links nuclear pore complex assembly and nuclear envelope formation. Mol. Cell 17 (2005) 83-92
    • (2005) Mol. Cell , vol.17 , pp. 83-92
    • Antonin, W.1    Franz, C.2    Haselmann, U.3    Antony, C.4    Mattaj, I.W.5
  • 4
    • 0026468354 scopus 로고
    • Characterization of a germ-line proliferation mutation in C. elegans
    • Beanan M.J., and Strome S. Characterization of a germ-line proliferation mutation in C. elegans. Development 116 (1992) 755-766
    • (1992) Development , vol.116 , pp. 755-766
    • Beanan, M.J.1    Strome, S.2
  • 7
    • 34247363723 scopus 로고    scopus 로고
    • Oxidative modification of proteins: Age-related changes
    • Chakravarti B., and Chakravarti D.N. Oxidative modification of proteins: Age-related changes. Gerontology 53 (2007) 128-139
    • (2007) Gerontology , vol.53 , pp. 128-139
    • Chakravarti, B.1    Chakravarti, D.N.2
  • 9
    • 33745594822 scopus 로고    scopus 로고
    • Cellular analyses of the mitotic region in the Caenorhabditis elegans adult germ line
    • Crittenden S.L., Leonhard K.A., Byrd D.T., and Kimble J. Cellular analyses of the mitotic region in the Caenorhabditis elegans adult germ line. Mol. Biol. Cell 17 (2006) 3051-3061
    • (2006) Mol. Biol. Cell , vol.17 , pp. 3051-3061
    • Crittenden, S.L.1    Leonhard, K.A.2    Byrd, D.T.3    Kimble, J.4
  • 10
    • 32044433784 scopus 로고    scopus 로고
    • The role of the nuclear envelope in cellular organization
    • D'Angelo M.A., and Hetzer M.W. The role of the nuclear envelope in cellular organization. Cell. Mol. Life Sci. 63 (2006) 316-332
    • (2006) Cell. Mol. Life Sci. , vol.63 , pp. 316-332
    • D'Angelo, M.A.1    Hetzer, M.W.2
  • 11
    • 33645962474 scopus 로고    scopus 로고
    • Nuclear pores form de novo from both sides of the nuclear envelope
    • D'Angelo M.A., Anderson D.J., Richard E., and Hetzer M.W. Nuclear pores form de novo from both sides of the nuclear envelope. Science 312 (2006) 440-443
    • (2006) Science , vol.312 , pp. 440-443
    • D'Angelo, M.A.1    Anderson, D.J.2    Richard, E.3    Hetzer, M.W.4
  • 14
    • 42649144101 scopus 로고    scopus 로고
    • Oxidative and nitrative protein modifications in Parkinson's disease
    • Danielson S.R., and Andersen J.K. Oxidative and nitrative protein modifications in Parkinson's disease. Free Radic. Biol. Med. 44 (2008) 1787-1794
    • (2008) Free Radic. Biol. Med. , vol.44 , pp. 1787-1794
    • Danielson, S.R.1    Andersen, J.K.2
  • 15
    • 0023449881 scopus 로고
    • Nuclear pore complex contains a family of glycoproteins that includes p62: Glycosylation through a previously unidentified cellular pathway
    • Davis L.I., and Blobel G. Nuclear pore complex contains a family of glycoproteins that includes p62: Glycosylation through a previously unidentified cellular pathway. Proc. Natl. Acad. Sci. USA 84 (1987) 7552-7556
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 7552-7556
    • Davis, L.I.1    Blobel, G.2
  • 16
    • 0037174629 scopus 로고    scopus 로고
    • Timing requirements for insulin/IGF-1 signaling in C. elegans
    • Dillin A., Crawford D.K., and Kenyon C. Timing requirements for insulin/IGF-1 signaling in C. elegans. Science 298 (2002) 830-834
    • (2002) Science , vol.298 , pp. 830-834
    • Dillin, A.1    Crawford, D.K.2    Kenyon, C.3
  • 17
    • 0037128215 scopus 로고    scopus 로고
    • Tpr is localized within the nuclear basket of the pore complex and has a role in nuclear protein export
    • Frosst P., Guan T., Subauste C., Hahn K., and Gerace L. Tpr is localized within the nuclear basket of the pore complex and has a role in nuclear protein export. J. Cell Biol. 156 (2002) 617-630
    • (2002) J. Cell Biol. , vol.156 , pp. 617-630
    • Frosst, P.1    Guan, T.2    Subauste, C.3    Hahn, K.4    Gerace, L.5
  • 18
    • 0344875469 scopus 로고    scopus 로고
    • Caenorhabditis elegans nucleoporins Nup93 and Nup205 determine the limit of nuclear pore complex size exclusion in vivo
    • Galy V., Mattaj I.W., and Askjaer P. Caenorhabditis elegans nucleoporins Nup93 and Nup205 determine the limit of nuclear pore complex size exclusion in vivo. Mol. Biol. Cell 14 (2003) 5104-5115
    • (2003) Mol. Biol. Cell , vol.14 , pp. 5104-5115
    • Galy, V.1    Mattaj, I.W.2    Askjaer, P.3
  • 19
    • 0030824317 scopus 로고    scopus 로고
    • Nup93, a vertebrate homologue of yeast Nic96p, forms a complex with a novel 205-kDa protein and is required for correct nuclear pore assembly
    • Grandi P., Dang T., Pane N., Shevchenko A., Mann M., Forbes D., and Hurt E. Nup93, a vertebrate homologue of yeast Nic96p, forms a complex with a novel 205-kDa protein and is required for correct nuclear pore assembly. Mol. Biol. Cell 8 (1997) 2017-2038
    • (1997) Mol. Biol. Cell , vol.8 , pp. 2017-2038
    • Grandi, P.1    Dang, T.2    Pane, N.3    Shevchenko, A.4    Mann, M.5    Forbes, D.6    Hurt, E.7
  • 22
    • 0032782364 scopus 로고    scopus 로고
    • The daf-2 gene network for longevity regulates oxidative stress resistance and Mn-superoxide dismutase gene expression in Caenorhabditis elegans
    • Honda Y., and Honda S. The daf-2 gene network for longevity regulates oxidative stress resistance and Mn-superoxide dismutase gene expression in Caenorhabditis elegans. FASEB J. 13 (1999) 1385-1393
    • (1999) FASEB J. , vol.13 , pp. 1385-1393
    • Honda, Y.1    Honda, S.2
  • 23
    • 0027771804 scopus 로고
    • A C. elegans mutant that lives twice as long as wild type
    • Kenyon C., Chang J., Gensch E., Rudner A., and Tabtiang R. A C. elegans mutant that lives twice as long as wild type. Nature 366 (1993) 461-464
    • (1993) Nature , vol.366 , pp. 461-464
    • Kenyon, C.1    Chang, J.2    Gensch, E.3    Rudner, A.4    Tabtiang, R.5
  • 24
    • 0035887005 scopus 로고    scopus 로고
    • Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans
    • Ketting R.F., Fischer S.E., Bernstein E., Sijen T., Hannon G.J., and Plasterk R.H. Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans. Genes Dev. 15 (2001) 2654-2659
    • (2001) Genes Dev. , vol.15 , pp. 2654-2659
    • Ketting, R.F.1    Fischer, S.E.2    Bernstein, E.3    Sijen, T.4    Hannon, G.J.5    Plasterk, R.H.6
  • 25
    • 34447636066 scopus 로고    scopus 로고
    • Functional genomic approach to identify novel genes involved in the regulation of oxidative stress resistance and animal lifespan
    • Kim Y., and Sun H. Functional genomic approach to identify novel genes involved in the regulation of oxidative stress resistance and animal lifespan. Aging Cell 6 (2007) 489-503
    • (2007) Aging Cell , vol.6 , pp. 489-503
    • Kim, Y.1    Sun, H.2
  • 26
    • 0030813398 scopus 로고    scopus 로고
    • daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans
    • Kimura K.D., Tissenbaum H.A., Liu Y., and Ruvkun G. daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans. Science 277 (1997) 942-946
    • (1997) Science , vol.277 , pp. 942-946
    • Kimura, K.D.1    Tissenbaum, H.A.2    Liu, Y.3    Ruvkun, G.4
  • 28
    • 4344700329 scopus 로고    scopus 로고
    • Nucleoporins as components of the nuclear pore complex core structure and tpr as the architectural element of the nuclear basket
    • Krull S., Thyberg J., Bjorkroth B., Rackwitz H.R., and Cordes V.C. Nucleoporins as components of the nuclear pore complex core structure and tpr as the architectural element of the nuclear basket. Mol. Biol. Cell 15 (2004) 4261-4277
    • (2004) Mol. Biol. Cell , vol.15 , pp. 4261-4277
    • Krull, S.1    Thyberg, J.2    Bjorkroth, B.3    Rackwitz, H.R.4    Cordes, V.C.5
  • 29
    • 29044436414 scopus 로고    scopus 로고
    • Monitoring the permeability of the nuclear envelope during the cell cycle
    • Lenart P., and Ellenberg J. Monitoring the permeability of the nuclear envelope during the cell cycle. Methods 38 (2006) 17-24
    • (2006) Methods , vol.38 , pp. 17-24
    • Lenart, P.1    Ellenberg, J.2
  • 30
    • 0344835675 scopus 로고    scopus 로고
    • Nuclear envelope breakdown in starfish oocytes proceeds by partial NPC disassembly followed by a rapidly spreading fenestration of nuclear membranes
    • Lenart P., Rabut G., Daigle N., Hand A.R., Terasaki M., and Ellenberg J. Nuclear envelope breakdown in starfish oocytes proceeds by partial NPC disassembly followed by a rapidly spreading fenestration of nuclear membranes. J. Cell Biol. 160 (2003) 1055-1068
    • (2003) J. Cell Biol. , vol.160 , pp. 1055-1068
    • Lenart, P.1    Rabut, G.2    Daigle, N.3    Hand, A.R.4    Terasaki, M.5    Ellenberg, J.6
  • 31
    • 0013936110 scopus 로고
    • Isolation and fractionation of rat brain nuclei
    • Lovtrup-Rein H., and McEwen B.S. Isolation and fractionation of rat brain nuclei. J. Cell Biol. 30 (1966) 405-415
    • (1966) J. Cell Biol. , vol.30 , pp. 405-415
    • Lovtrup-Rein, H.1    McEwen, B.S.2
  • 32
    • 0015433823 scopus 로고
    • Time sequence of nuclear pore formation in phytohemagglutinin-stimulated lymphocytes and in HeLa cells during the cell cycle
    • Maul G.G., Maul H.M., Scogna J.E., Lieberman M.W., Stein G.S., Hsu B.Y., and Borun T.W. Time sequence of nuclear pore formation in phytohemagglutinin-stimulated lymphocytes and in HeLa cells during the cell cycle. J. Cell Biol. 55 (1972) 433-447
    • (1972) J. Cell Biol. , vol.55 , pp. 433-447
    • Maul, G.G.1    Maul, H.M.2    Scogna, J.E.3    Lieberman, M.W.4    Stein, G.S.5    Hsu, B.Y.6    Borun, T.W.7
  • 33
    • 0034772838 scopus 로고    scopus 로고
    • Oxidative stress causes abnormal accumulation of familial amyotrophic lateral sclerosis-related mutant SOD1 in transgenic Caenorhabditis elegans
    • Oeda T., Shimohama S., Kitagawa N., Kohno R., Imura T., Shibasaki H., and Ishii N. Oxidative stress causes abnormal accumulation of familial amyotrophic lateral sclerosis-related mutant SOD1 in transgenic Caenorhabditis elegans. Hum. Mol. Genet. 10 (2001) 2013-2023
    • (2001) Hum. Mol. Genet. , vol.10 , pp. 2013-2023
    • Oeda, T.1    Shimohama, S.2    Kitagawa, N.3    Kohno, R.4    Imura, T.5    Shibasaki, H.6    Ishii, N.7
  • 34
    • 34249888736 scopus 로고    scopus 로고
    • PHA-4/Foxa mediates diet-restriction-induced longevity of C. elegans
    • Panowski S.H., Wolff S., Aguilaniu H., Durieux J., and Dillin A. PHA-4/Foxa mediates diet-restriction-induced longevity of C. elegans. Nature 447 (2007) 550-555
    • (2007) Nature , vol.447 , pp. 550-555
    • Panowski, S.H.1    Wolff, S.2    Aguilaniu, H.3    Durieux, J.4    Dillin, A.5
  • 35
    • 7944236264 scopus 로고    scopus 로고
    • Mapping the dynamic organization of the nuclear pore complex inside single living cells
    • Rabut G., Doye V., and Ellenberg J. Mapping the dynamic organization of the nuclear pore complex inside single living cells. Nat. Cell Biol. 6 (2004) 1114-1121
    • (2004) Nat. Cell Biol. , vol.6 , pp. 1114-1121
    • Rabut, G.1    Doye, V.2    Ellenberg, J.3
  • 36
    • 2342513330 scopus 로고    scopus 로고
    • Dynamics of nuclear pore complex organization through the cell cycle
    • Rabut G., Lenart P., and Ellenberg J. Dynamics of nuclear pore complex organization through the cell cycle. Curr. Opin. Cell Biol. 16 (2004) 314-321
    • (2004) Curr. Opin. Cell Biol. , vol.16 , pp. 314-321
    • Rabut, G.1    Lenart, P.2    Ellenberg, J.3
  • 37
  • 38
    • 0025247954 scopus 로고
    • Correlation between structure and mass distribution of the nuclear pore complex and of distinct pore complex components
    • Reichelt R., Holzenburg A., Buhle Jr. E.L., Jarnik M., Engel A., and Aebi U. Correlation between structure and mass distribution of the nuclear pore complex and of distinct pore complex components. J. Cell Biol. 110 (1990) 883-894
    • (1990) J. Cell Biol. , vol.110 , pp. 883-894
    • Reichelt, R.1    Holzenburg, A.2    Buhle Jr., E.L.3    Jarnik, M.4    Engel, A.5    Aebi, U.6
  • 39
    • 0027454503 scopus 로고
    • The Sec13p complex and reconstitution of vesicle budding from the ER with purified cytosolic proteins
    • Salama N.R., Yeung T., and Schekman R.W. The Sec13p complex and reconstitution of vesicle budding from the ER with purified cytosolic proteins. EMBO J. 12 (1993) 4073-4082
    • (1993) EMBO J. , vol.12 , pp. 4073-4082
    • Salama, N.R.1    Yeung, T.2    Schekman, R.W.3
  • 40
    • 33646745137 scopus 로고    scopus 로고
    • Lamin A-dependent nuclear defects in human aging
    • Scaffidi P., and Misteli T. Lamin A-dependent nuclear defects in human aging. Science 312 (2006) 1059-1063
    • (2006) Science , vol.312 , pp. 1059-1063
    • Scaffidi, P.1    Misteli, T.2
  • 41
    • 49649106438 scopus 로고    scopus 로고
    • A mechanism for asymmetric segregation of age during yeast budding
    • Shcheprova Z., Baldi S., Frei S.B., Gonnet G., and Barral Y. A mechanism for asymmetric segregation of age during yeast budding. Nature 454 (2008) 728-734
    • (2008) Nature , vol.454 , pp. 728-734
    • Shcheprova, Z.1    Baldi, S.2    Frei, S.B.3    Gonnet, G.4    Barral, Y.5
  • 43
    • 0037459085 scopus 로고    scopus 로고
    • Regulating access to the genome: Nucleocytoplasmic transport throughout the cell cycle
    • Weis K. Regulating access to the genome: Nucleocytoplasmic transport throughout the cell cycle. Cell 112 (2003) 441-451
    • (2003) Cell , vol.112 , pp. 441-451
    • Weis, K.1
  • 44
    • 33846262456 scopus 로고    scopus 로고
    • Abnormalities of the nucleus and nuclear inclusions in neurodegenerative disease: A work in progress
    • Woulfe J.M. Abnormalities of the nucleus and nuclear inclusions in neurodegenerative disease: A work in progress. Neuropathol. Appl. Neurobiol. 33 (2007) 2-42
    • (2007) Neuropathol. Appl. Neurobiol. , vol.33 , pp. 2-42
    • Woulfe, J.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.