SCOPUS 정보 검색 플랫폼

Macromolecular Bioscience

Volumn 15, Issue 5, 2015, Pages 589-599

The role of matrix compliance on cell responses to drugs and toxins: Towards predictive drug screening platforms

(1) Zustiak, Silviya Petrova a

a Saint Louis University (United States)

Author keywords

compliance; drug screening; matrix; substrate stiffness; therapeutics

Indexed keywords

BIOLOGICAL MATERIALS; CELLS; CYTOLOGY; DRUG INTERACTIONS; INTERFACES (MATERIALS); MATRIX ALGEBRA; METABOLITES; STIFFNESS; STIFFNESS MATRIX; SUBSTRATES; TISSUE ENGINEERING;

CELL RESPONSE; COMPLIANCE; DRUG SCREENING; HIGH THROUGHPUT; IN-VITRO MODELS; SUBSTRATE STIFFNESS; THERAPEUTICS; TISSUE MODELS;

TISSUE;

BIOMATERIAL; DRUG; TOXIN;

ASSAY; BIOMECHANICS; CANCER SUSCEPTIBILITY; CELL ADHESION; CELL CYCLE G2 PHASE; CELL CYCLE PROGRESSION; CELL FATE; CELL FUNCTION; CELL MEMBRANE PERMEABILITY; CELLULAR PARAMETERS; CYTOTOXICITY; DRUG DEVELOPMENT; DRUG SCREENING; ENDOPLASMIC RETICULUM STRESS; EXTRACELLULAR MATRIX; HIGH THROUGHPUT SCREENING; HUMAN; MORTALITY; NONHUMAN; REPRODUCIBILITY; REVIEW; STIFFNESS ASSAY; STUDY; SUBSTRATE COMPLIANCE; TUMOR INVASION; YOUNG MODULUS; ANIMAL; MATERIALS TESTING; METABOLISM;

ANIMALS; BIOCOMPATIBLE MATERIALS; DRUG EVALUATION, PRECLINICAL; EXTRACELLULAR MATRIX; HUMANS; MATERIALS TESTING; PHARMACEUTICAL PREPARATIONS; TOXINS, BIOLOGICAL;

EID: 84929078855 PISSN: 16165187 EISSN: 16165195 Source Type: Journal
DOI: 10.1002/mabi.201400507 Document Type: Review

Times cited : (12)

References (101)

1
- 18244366662
- L. G. Griffith, G. Naughton, Science 2002, 295, 1009.
- (2002) Science , vol.295 , pp. 1009
- Griffith, L.G.¹ Naughton, G.²

2
- 77951672406
- J. Giacomotto, L. Segalat, Br. J. Pharmacol. 2010, 160, 204.
- (2010) Br. J. Pharmacol. , vol.160 , pp. 204
- Giacomotto, J.¹ Segalat, L.²

3
- 34648834682
- F. Pampaloni, E. G. Reynaud, E. H. Stelzer, Nat. Rev. Mol. Cell Biol. 2007, 8, 839.
- (2007) Nat. Rev. Mol. Cell Biol. , vol.8 , pp. 839
- Pampaloni, F.¹ Reynaud, E.G.² Stelzer, E.H.³

4
- 43549114744
- W. Lilienblum, W. Dekant, H. Foth, T. Gebel, J. G. Hengstler, R. Kahl, P. J. Kramer, H. Schweinfurth, K. M. Wollin, Arch. Toxicol. 2008, 82, 211.
- (2008) Arch. Toxicol. , vol.82 , pp. 211
- Lilienblum, W.¹ Dekant, W.² Foth, H.³ Gebel, T.⁴ Hengstler, J.G.⁵ Kahl, R.⁶ Kramer, P.J.⁷ Schweinfurth, H.⁸ Wollin, K.M.⁹

5
- 84907411288
- F. S. Collins, Sci. Translat. Med. 2011, 3, 90cm17.
- (2011) Sci. Translat. Med. , vol.3 , pp. 90cm17
- Collins, F.S.¹

6
- 0344912596
- R. J. Pelham, Jr., Y.-L. Wang, Proc. Natl. Acad. Sci. USA 1997, 94, 13661.
- (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 13661
- Pelham, R.J.¹ Wang, Y.-L.²

7
- 27944497333
- D. E. Discher, P. Janmey, Y.-L. Wang, Science 2005, 310, 1139.
- (2005) Science , vol.310 , pp. 1139
- Discher, D.E.¹ Janmey, P.² Wang, Y.-L.³

8
- 33747152561
- A. J. Engler, S. Sen, H. L. Sweeney, D. E. Discher, Cell 2006, 126, 677.
- (2006) Cell , vol.126 , pp. 677
- Engler, A.J.¹ Sen, S.² Sweeney, H.L.³ Discher, D.E.⁴

9
- 19944428596
- T. Yeung, P. C. Georges, L. A. Flanagan, B. Marg, M. Ortiz, M. Funaki, N. Zahir, W. Ming, V. Weaver, P. A. Janmey, Cell Motil. Cytoskel. 2005, 60, 24.
- (2005) Cell Motil. Cytoskel. , vol.60 , pp. 24
- Yeung, T.¹ Georges, P.C.² Flanagan, L.A.³ Marg, B.⁴ Ortiz, M.⁵ Funaki, M.⁶ Zahir, N.⁷ Ming, W.⁸ Weaver, V.⁹ Janmey, P.A.¹⁰

10
- 78650062139
- N. T. Elliott, F. Yuan, J. Pharm. Sci. 2011, 100, 59.
- (2011) J. Pharm. Sci. , vol.100 , pp. 59
- Elliott, N.T.¹ Yuan, F.²

11
- 81355146382
- D. Huh, G. A. Hamilton, D. E. Ingber, Trends Cell Biol. 2011, 21, 745.
- (2011) Trends Cell Biol. , vol.21 , pp. 745
- Huh, D.¹ Hamilton, G.A.² Ingber, D.E.³

12
- 84856441579
- A. M. Ghaemmaghami, M. J. Hancock, H. Harrington, H. Kaji, A. Khademhosseini, Drug Discov. Today 2012, 17, 173.
- (2012) Drug Discov. Today , vol.17 , pp. 173
- Ghaemmaghami, A.M.¹ Hancock, M.J.² Harrington, H.³ Kaji, H.⁴ Khademhosseini, A.⁵

13
- 38349143408
- G. D. Prestwich, Acc. Chem. Res. 2007, 41, 139.
- (2007) Acc. Chem. Res. , vol.41 , pp. 139
- Prestwich, G.D.¹

14
- 79957778562
- W. L. Chen, C. A. Simmons, Adv. Drug Deliv. Rev. 2011, 63, 269.
- (2011) Adv. Drug Deliv. Rev. , vol.63 , pp. 269
- Chen, W.L.¹ Simmons, C.A.²

15
- 33749011163
- R. H. Shoemaker, Nat. Rev. Cancer 2006, 6, 813.
- (2006) Nat. Rev. Cancer , vol.6 , pp. 813
- Shoemaker, R.H.¹

16
- 34347230544
- V. Vichai, K. Kirtikara, Nat. Protocols 2006, 1, 1112.
- (2006) Nat. Protocols , vol.1 , pp. 1112
- Vichai, V.¹ Kirtikara, K.²

17
- 3042820950
- J. A. Hubbell, Nat. Biotechnol. 2004, 22, 828.
- (2004) Nat. Biotechnol. , vol.22 , pp. 828
- Hubbell, J.A.¹

18
- 50449110852
- M. Yliperttula, B. G. Chung, A. Navaladi, A. Manbachi, A. Urtti, Eur. J. Pharm. Sci. 2008, 35, 151.
- (2008) Eur. J. Pharm. Sci. , vol.35 , pp. 151
- Yliperttula, M.¹ Chung, B.G.² Navaladi, A.³ Manbachi, A.⁴ Urtti, A.⁵

19
- 84899994032
- M. B. Esch, A. S. Smith, J.-M. Prot, C. Oleaga, J. J. Hickman, M. L. Shuler, Adv. Drug Deliv. Rev. 2014, 69, 158.
- (2014) Adv. Drug Deliv. Rev. , vol.69 , pp. 158
- Esch, M.B.¹ Smith, A.S.² Prot, J.-M.³ Oleaga, C.⁴ Hickman, J.J.⁵ Shuler, M.L.⁶

20
- 0000463651
- S. Huang, D. E. Ingber, Nat. Cell Biol. 1999, 1, E131.
- (1999) Nat. Cell Biol. , vol.1 , pp. E131
- Huang, S.¹ Ingber, D.E.²

21
- 67650169752
- M. W. Tibbitt, K. S. Anseth, Biotechnol. Bioeng. 2009, 103, 655.
- (2009) Biotechnol. Bioeng. , vol.103 , pp. 655
- Tibbitt, M.W.¹ Anseth, K.S.²

22
- 77951218278
- H. Geckil, F. Xu, X. Zhang, S. Moon, U. Demirci, Nanomedicine 2010, 5, 469.
- (2010) Nanomedicine , vol.5 , pp. 469
- Geckil, H.¹ Xu, F.² Zhang, X.³ Moon, S.⁴ Demirci, U.⁵

23
- 66249146049
- E. S. Place, N. D. Evans, M. M. Stevens, Nat. Mater. 2009, 8, 457.
- (2009) Nat. Mater. , vol.8 , pp. 457
- Place, E.S.¹ Evans, N.D.² Stevens, M.M.³

24
- 80155205233
- S. Gobaa, S. Hoehnel, M. Roccio, A. Negro, S. Kobel, M. P. Lutolf, Nat. Methods 2011, 8, 949.
- (2011) Nat. Methods , vol.8 , pp. 949
- Gobaa, S.¹ Hoehnel, S.² Roccio, M.³ Negro, A.⁴ Kobel, S.⁵ Lutolf, M.P.⁶

25
- 78650271558
- A. Kumachev, J. Greener, E. Tumarkin, E. Eiser, P. W. Zandstra, E. Kumacheva, Biomaterials 2011, 32, 1477.
- (2011) Biomaterials , vol.32 , pp. 1477
- Kumachev, A.¹ Greener, J.² Tumarkin, E.³ Eiser, E.⁴ Zandstra, P.W.⁵ Kumacheva, E.⁶

26
- 84858251023
- T. Rossow, J. A. Heyman, A. J. Ehrlicher, A. Langhoff, D. A. Weitz, R. Haag, S. Seiffert, J. Am. Chem. Soc. 2012, 134, 4983.
- (2012) J. Am. Chem. Soc. , vol.134 , pp. 4983
- Rossow, T.¹ Heyman, J.A.² Ehrlicher, A.J.³ Langhoff, A.⁴ Weitz, D.A.⁵ Haag, R.⁶ Seiffert, S.⁷

27
- 79952200356
- (Eds: A. Khademhosseini, K.-Y. Suh, M. Zourob), Springer, Berlin/New York, Ch. 13
- R. C. Chang, K. Emami, A. Jeevarajan, H. Wu, W. Sun, in Biological Microarrays (Eds:, A. Khademhosseini, K.-Y. Suh, M. Zourob,), Springer, Berlin/New York 2011, Ch. 13, p. 219.
- (2011) Biological Microarrays , pp. 219
- Chang, R.C.¹ Emami, K.² Jeevarajan, A.³ Wu, H.⁴ Sun, W.⁵

28
- 77954962994
- 2019
- K. Gupta, D.-H. Kim, D. Ellison, C. Smith, A. Kundu, J. Tuan, K.-Y. Suh, A. Levchenko, Lab Chip 2010, 10, 2019.
- (2010) Lab Chip , vol.10
- Gupta, K.¹ Kim, D.-H.² Ellison, D.³ Smith, C.⁴ Kundu, A.⁵ Tuan, J.⁶ Suh, K.-Y.⁷ Levchenko, A.⁸

29
- 84887561836
- C. Y. Chan, P.-H. Huang, F. Guo, X. Ding, V. Kapur, J. D. Mai, P. K. Yuen, T. J. Huang, Lab Chip 2013, 13, 4697.
- (2013) Lab Chip , vol.13 , pp. 4697
- Chan, C.Y.¹ Huang, P.-H.² Guo, F.³ Ding, X.⁴ Kapur, V.⁵ Mai, J.D.⁶ Yuen, P.K.⁷ Huang, T.J.⁸

30
- 84890803299
- S. Zustiak, R. Nossal, D. L. Sackett, Biotechnol. Bioeng. 2014, 111, 396.
- (2014) Biotechnol. Bioeng. , vol.111 , pp. 396
- Zustiak, S.¹ Nossal, R.² Sackett, D.L.³

31
- 79957586828
- J. D. Mih, A. S. Sharif, F. Liu, A. Marinkovic, M. M. Symer, D. J. Tschumperlin, PloS ONE 2011, 6, e19929.
- (2011) PloS ONE , vol.6 , pp. e19929
- Mih, J.D.¹ Sharif, A.S.² Liu, F.³ Marinkovic, A.⁴ Symer, M.M.⁵ Tschumperlin, D.J.⁶

32
- 82955194744
- J. A. Wood, C. T. McKee, S. M. Thomasy, M. E. Fischer, N. M. Shah, C. J. Murphy, P. Russell, Invest. Ophthalm. Vis. Sci. 2011, 52, 9298.
- (2011) Invest. Ophthalm. Vis. Sci. , vol.52 , pp. 9298
- Wood, J.A.¹ McKee, C.T.² Thomasy, S.M.³ Fischer, M.E.⁴ Shah, N.M.⁵ Murphy, C.J.⁶ Russell, P.⁷

33
- 84880081017
- W. G. Herrick, T. V. Nguyen, M. Sleiman, S. McRae, T. S. Emrick, S. R. Peyton, Biomacromolecules 2013, 14, 2294.
- (2013) Biomacromolecules , vol.14 , pp. 2294
- Herrick, W.G.¹ Nguyen, T.V.² Sleiman, M.³ McRae, S.⁴ Emrick, T.S.⁵ Peyton, S.R.⁶

34
- 84896694541
- E. Y. Tokuda, J. L. Leight, K. S. Anseth, Biomaterials 2014, 35, 4310.
- (2014) Biomaterials , vol.35 , pp. 4310
- Tokuda, E.Y.¹ Leight, J.L.² Anseth, K.S.³

35
- 84887857597
- J. Feng, Y. Tang, Y. Xu, Q. Sun, F. Liao, D. Han, Clin. Hemorheol. Microcirc. 2013, 55, 121.
- (2013) Clin. Hemorheol. Microcirc. , vol.55 , pp. 121
- Feng, J.¹ Tang, Y.² Xu, Y.³ Sun, Q.⁴ Liao, F.⁵ Han, D.⁶

36
- 84903794962
- K. Ramamoorthi, J. Hara, C. Ito, P. Asuri, Cell. Mol. Bioeng. 2014, 7, 278.
- (2014) Cell. Mol. Bioeng. , vol.7 , pp. 278
- Ramamoorthi, K.¹ Hara, J.² Ito, C.³ Asuri, P.⁴

37
- 33847036735
- I. Levental, P. C. Georges, P. A. Janmey, Soft Matter 2007, 3, 299.
- (2007) Soft Matter , vol.3 , pp. 299
- Levental, I.¹ Georges, P.C.² Janmey, P.A.³

38
- 77953816876
- Suppl. 10.16.1-10.16.16
- J. R. Tse, A. J. Engler, Curr. Protocols Cell Biol. 2010, Suppl. 47, 10.16.1-10.16.16.
- (2010) Curr. Protocols Cell Biol. , vol.47
- Tse, J.R.¹ Engler, A.J.²

39
- 79251540221
- R. T. Justin, A. J. Engler, PloS ONE 2011, 6, e15978.
- (2011) PloS ONE , vol.6 , pp. e15978
- Justin, R.T.¹ Engler, A.J.²

40
- 84929121550
- In Press
- S. Syed, A. Karadaghy, S. Zustiak, J. Vis. Experiments In Press.
- J. Vis. Experiments
- Syed, S.¹ Karadaghy, A.² Zustiak, S.³

41
- 84860526569
- D. A. Patel, A. C. Patel, W. C. Nolan, Y. Zhang, M. J. Holtzman, PloS ONE 2012, 7, e36594.
- (2012) PloS ONE , vol.7 , pp. e36594
- Patel, D.A.¹ Patel, A.C.² Nolan, W.C.³ Zhang, Y.⁴ Holtzman, M.J.⁵

42
- 77956318381
- J. Fu, Y. K. Wang, M. T. Yang, R. A. Desai, X. Yu, Z. Liu, C. S. Chen, Nat. Methods 2010, 7, 733.
- (2010) Nat. Methods , vol.7 , pp. 733
- Fu, J.¹ Wang, Y.K.² Yang, M.T.³ Desai, R.A.⁴ Yu, X.⁵ Liu, Z.⁶ Chen, C.S.⁷

43
- 0037452695
- J. L. Tan, J. Tien, D. M. Pirone, D. S. Gray, K. Bhadriraju, C. S. Chen, Proc. Natl. Acad. Sci. USA 2003, 100, 1484.
- (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 1484
- Tan, J.L.¹ Tien, J.² Pirone, D.M.³ Gray, D.S.⁴ Bhadriraju, K.⁵ Chen, C.S.⁶

44
- 84860917121
- M. Nikkhah, F. Edalat, S. Manoucheri, A. Khademhosseini, Biomaterials 2012, 33, 5230.
- (2012) Biomaterials , vol.33 , pp. 5230
- Nikkhah, M.¹ Edalat, F.² Manoucheri, S.³ Khademhosseini, A.⁴

45
- 77956075225
- P. Ayala, J. I. Lopez, T. A. Desai, Tissue Eng., Part A 2010, 16, 2519.
- (2010) Tissue Eng., Part A , vol.16 , pp. 2519
- Ayala, P.¹ Lopez, J.I.² Desai, T.A.³

46
- 77950419650
- S. Grimm, J. Martín, G. Rodriguez, M. Fernández-Gutierrez, K. Mathwig, R. B. Wehrspohn, U. Gösele, J. San Roman, C. Mijangosn, M. Steinhart, J. Mater. Chem. 2010, 20, 3171.
- (2010) J. Mater. Chem. , vol.20 , pp. 3171
- Grimm, S.¹ Martín, J.² Rodriguez, G.³ Fernández-Gutierrez, M.⁴ Mathwig, K.⁵ Wehrspohn, R.B.⁶ Gösele, U.⁷ San Roman, J.⁸ Mijangosn, C.⁹ Steinhart, M.¹⁰

47
- 77956335155
- A. Buxboim, D. E. Discher, Nat. Methods 2010, 7, 695.
- (2010) Nat. Methods , vol.7 , pp. 695
- Buxboim, A.¹ Discher, D.E.²

48
- 79551661682
- M. T. Yang, J. Fu, Y.-K. Wang, R. A. Desai, C. S. Chen, Nat. Protocols 2011, 6, 187.
- (2011) Nat. Protocols , vol.6 , pp. 187
- Yang, M.T.¹ Fu, J.² Wang, Y.-K.³ Desai, R.A.⁴ Chen, C.S.⁵

49
- 21844439727
- C. A. Lemmon, N. J. Sniadecki, S. A. Ruiz, J. L. Tan, L. H. Romer, C. S. Chen, Mechanics Chem. Biosyst.: MCB 2005, 2, 1.
- (2005) Mechanics Chem. Biosyst.: MCB , vol.2 , pp. 1
- Lemmon, C.A.¹ Sniadecki, N.J.² Ruiz, S.A.³ Tan, J.L.⁴ Romer, L.H.⁵ Chen, C.S.⁶

50
- 57249086295
- S. Ghassemi, N. Biais, K. Maniura, S. Wind, M. Sheetz, J. Hone, J. Vac. Sci. Technol. B 2008, 26, 2549.
- (2008) J. Vac. Sci. Technol. B , vol.26 , pp. 2549
- Ghassemi, S.¹ Biais, N.² Maniura, K.³ Wind, S.⁴ Sheetz, M.⁵ Hone, J.⁶

51
- 67651149786
- D.-H. Kim, P. K. Wong, J. Park, A. Levchenko, Y. Sun, Annu. Rev. Biomed. Eng. 2009, 11, 203.
- (2009) Annu. Rev. Biomed. Eng. , vol.11 , pp. 203
- Kim, D.-H.¹ Wong, P.K.² Park, J.³ Levchenko, A.⁴ Sun, Y.⁵

52
- 77955968267
- D. Maltman, S. Przyborski, Biochem. Soc. Trans. 2010, 38, 1072.
- (2010) Biochem. Soc. Trans. , vol.38 , pp. 1072
- Maltman, D.¹ Przyborski, S.²

53
- 81355146382
- D. Huh, G. A. Hamilton, D. E. Ingber, Trends Cell Biol. 2011, 21, 745.
- (2011) Trends Cell Biol. , vol.21 , pp. 745
- Huh, D.¹ Hamilton, G.A.² Ingber, D.E.³

54
- 77955914547
- F. Liu, J. D. Mih, B. S. Shea, A. T. Kho, A. S. Sharif, A. M. Tager, D. J. Tschumperlin, J. Cell Biol. 2010, 190, 693.
- (2010) J. Cell Biol. , vol.190 , pp. 693
- Liu, F.¹ Mih, J.D.² Shea, B.S.³ Kho, A.T.⁴ Sharif, A.S.⁵ Tager, A.M.⁶ Tschumperlin, D.J.⁷

55
- 0037452695
- J. L. Tan, J. Tien, D. M. Pirone, D. S. Gray, K. Bhadriraju, C. S. Chen, Proc. Natl. Acad. Sci. USA 2003, 100, 1484.
- (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 1484
- Tan, J.L.¹ Tien, J.² Pirone, D.M.³ Gray, D.S.⁴ Bhadriraju, K.⁵ Chen, C.S.⁶

56
- 36148930613
- K. Ghosh, D. E. Ingber, Adv. Drug Delivery Rev. 2007, 59, 1306.
- (2007) Adv. Drug Delivery Rev. , vol.59 , pp. 1306
- Ghosh, K.¹ Ingber, D.E.²

57
- 34648834682
- F. Pampaloni, E. G. Reynaud, E. H. Stelzer, Nat. Rev. Mol. Cell Biol. 2007, 8, 839.
- (2007) Nat. Rev. Mol. Cell Biol. , vol.8 , pp. 839
- Pampaloni, F.¹ Reynaud, E.G.² Stelzer, E.H.³

58
- 70349329669
- D. W. Hutmacher, R. E. Horch, D. Loessner, S. Rizzi, S. Sieh, J. C. Reichert, J. A. Clements, J. P. Beier, A. Arkudas, O. Bleiziffer, J. Cell. Mol. Med. 2009, 13, 1417.
- (2009) J. Cell. Mol. Med. , vol.13 , pp. 1417
- Hutmacher, D.W.¹ Horch, R.E.² Loessner, D.³ Rizzi, S.⁴ Sieh, S.⁵ Reichert, J.C.⁶ Clements, J.A.⁷ Beier, J.P.⁸ Arkudas, A.⁹ Bleiziffer, O.¹⁰

59
- 77952124277
- S. P. Zustiak, J. B. Leach, Biomacromolecules 2010, 11, 1348.
- (2010) Biomacromolecules , vol.11 , pp. 1348
- Zustiak, S.P.¹ Leach, J.B.²

60
- 0034696350
- M. D. Sternlicht, M. J. Bissell, Z. Werb, Oncogene 2000, 19, 1102.
- (2000) Oncogene , vol.19 , pp. 1102
- Sternlicht, M.D.¹ Bissell, M.J.² Werb, Z.³

61
- 0033597726
- M. D. Sternlicht, A. Lochter, C. J. Sympson, B. Huey, J. P. Rougier, J. W. Gray, D. Pinkel, M. J. Bissell, Z. Werb, Cell 1999, 98, 137.
- (1999) Cell , vol.98 , pp. 137
- Sternlicht, M.D.¹ Lochter, A.² Sympson, C.J.³ Huey, B.⁴ Rougier, J.P.⁵ Gray, J.W.⁶ Pinkel, D.⁷ Bissell, M.J.⁸ Werb, Z.⁹

62
- 24944547482
- M. J. Paszek, N. Zahir, K. R. Johnson, J. N. Lakins, G. I. Rozenberg, A. Gefen, C. A. Reinhart-King, S. S. Margulies, M. Dembo, D. Boettiger, D. A. Hammer, V. M. Weaver, Cancer Cell 2005, 8, 241.
- (2005) Cancer Cell , vol.8 , pp. 241
- Paszek, M.J.¹ Zahir, N.² Johnson, K.R.³ Lakins, J.N.⁴ Rozenberg, G.I.⁵ Gefen, A.⁶ Reinhart-King, C.A.⁷ Margulies, S.S.⁸ Dembo, M.⁹ Boettiger, D.¹⁰ Hammer, D.A.¹¹ Weaver, V.M.¹²

63
- 24944436269
- S. Huang, D. E. Ingber, Cancer Cell 2005, 8, 175.
- (2005) Cancer Cell , vol.8 , pp. 175
- Huang, S.¹ Ingber, D.E.²

64
- 70450222098
- K. R. Levental, H. Yu, L. Kass, J. N. Lakins, M. Egeblad, J. T. Erler, S. F. Fong, K. Csiszar, A. Giaccia, W. Weninger, M. Yamauchi, D. L. Gasser, V. M. Weaver, Cell 2009, 139, 891.
- (2009) Cell , vol.139 , pp. 891
- Levental, K.R.¹ Yu, H.² Kass, L.³ Lakins, J.N.⁴ Egeblad, M.⁵ Erler, J.T.⁶ Fong, S.F.⁷ Csiszar, K.⁸ Giaccia, A.⁹ Weninger, W.¹⁰ Yamauchi, M.¹¹ Gasser, D.L.¹² Weaver, V.M.¹³

65
- 0028708677
- S. Horwitz, Ann. Oncol. 1993, 5, S3.
- (1993) Ann. Oncol. , vol.5 , pp. S3
- Horwitz, S.¹

66
- 0038216623
- M. Abal, J. Andreu, I. Barasoain, Curr. Cancer Drug Targets 2003, 3, 193.
- (2003) Curr. Cancer Drug Targets , vol.3 , pp. 193
- Abal, M.¹ Andreu, J.² Barasoain, I.³

67
- 0025273308
- C. M. Sorenson, M. A. Barry, A. Eastman, J. Natl. Cancer Inst. 1990, 82, 749.
- (1990) J. Natl. Cancer Inst. , vol.82 , pp. 749
- Sorenson, C.M.¹ Barry, M.A.² Eastman, A.³

68
- 84899979596
- T. V. Nguyen, M. Sleiman, T. Moriarty, W. G. Herrick, S. R. Peyton, Biomaterials 2014, 35, 5749.
- (2014) Biomaterials , vol.35 , pp. 5749
- Nguyen, T.V.¹ Sleiman, M.² Moriarty, T.³ Herrick, W.G.⁴ Peyton, S.R.⁵

69
- 0035525733
- I. Herr, K.-M. Debatin, Blood 2001, 98, 2603.
- (2001) Blood , vol.98 , pp. 2603
- Herr, I.¹ Debatin, K.-M.²

70
- 79953736762
- J. Schrader, T. T. Gordon-Walker, R. L. Aucott, M. van Deemter, A. Quaas, S. Walsh, D. Benten, S. J. Forbes, R. G. Wells, J. P. Iredale, Hepatology 2011, 53, 1192.
- (2011) Hepatology , vol.53 , pp. 1192
- Schrader, J.¹ Gordon-Walker, T.T.² Aucott, R.L.³ Van Deemter, M.⁴ Quaas, A.⁵ Walsh, S.⁶ Benten, D.⁷ Forbes, S.J.⁸ Wells, R.G.⁹ Iredale, J.P.¹⁰

71
- 1642617693
- J. Á.F. Vara, E. Casado, J. de Castro, P. Cejas, C. Belda-Iniesta, M. González-Barõn, Cancer Treat. Rev. 2004, 30, 193.
- (2004) Cancer Treat. Rev. , vol.30 , pp. 193
- Vara J.Á., F.¹ Casado, E.² De Castro, J.³ Cejas, P.⁴ Belda-Iniesta, C.⁵ González-Barõn, M.⁶

72
- 33745075558
- K. S. Smalley, N. K. Haass, P. A. Brafford, M. Lioni, K. T. Flaherty, M. Herlyn, Mol. Cancer Ther. 2006, 5, 1136.
- (2006) Mol. Cancer Ther. , vol.5 , pp. 1136
- Smalley, K.S.¹ Haass, N.K.² Brafford, P.A.³ Lioni, M.⁴ Flaherty, K.T.⁵ Herlyn, M.⁶

73
- 78751705159
- C. T. McKee, J. A. Wood, N. M. Shah, M. E. Fischer, C. M. Reilly, C. J. Murphy, P. Russell, Biomaterials 2011, 32, 2417.
- (2011) Biomaterials , vol.32 , pp. 2417
- McKee, C.T.¹ Wood, J.A.² Shah, N.M.³ Fischer, M.E.⁴ Reilly, C.M.⁵ Murphy, C.J.⁶ Russell, P.⁷

74
- 58149178486
- B. A. Justice, N. A. Badr, R. A. Felder, Drug Discov. Today 2009, 14, 102.
- (2009) Drug Discov. Today , vol.14 , pp. 102
- Justice, B.A.¹ Badr, N.A.² Felder, R.A.³

75
- 84919691161
- M. Alemany-Ribes, C. E. Semino, Adv. Drug Deliv. Rev. 2014, 79-80C, 40.
- (2014) Adv. Drug Deliv. Rev. , vol.7980 , pp. 40
- Alemany-Ribes, M.¹ Semino, C.E.²

76
- 84874700631
- S. Breslin, L. O'Driscoll, Drug Discov. Today 2013, 18, 240.
- (2013) Drug Discov. Today , vol.18 , pp. 240
- Breslin, S.¹ O'Driscoll, L.²

77
- 84899945356
- C. R. Thoma, M. Zimmermann, I. Agarkova, J. M. Kelm, W. Krek, Adv. Drug Deliv. Rev. 2014, 69-70, 29.
- (2014) Adv. Drug Deliv. Rev. , vol.6970 , pp. 29
- Thoma, C.R.¹ Zimmermann, M.² Agarkova, I.³ Kelm, J.M.⁴ Krek, W.⁵

78
- 84886952145
- D. Cigognini, A. Lomas, P. Kumar, A. Satyam, A. English, A. Azeem, A. Pandit, D. Zeugolis, Drug Discov. Today 2013, 18, 1099.
- (2013) Drug Discov. Today , vol.18 , pp. 1099
- Cigognini, D.¹ Lomas, A.² Kumar, P.³ Satyam, A.⁴ English, A.⁵ Azeem, A.⁶ Pandit, A.⁷ Zeugolis, D.⁸

79
- 79956337423
- M. A. Kotlarchyk, S. G. Shreim, M. B. Alvarez-Elizondo, L. C. Estrada, R. Singh, L. Valdevit, E. Kniazeva, E. Gratton, A. J. Putnam, E. L. Botvinick, PloS ONE 2011, 6, e20201.
- (2011) PloS ONE , vol.6 , pp. e20201
- Kotlarchyk, M.A.¹ Shreim, S.G.² Alvarez-Elizondo, M.B.³ Estrada, L.C.⁴ Singh, R.⁵ Valdevit, L.⁶ Kniazeva, E.⁷ Gratton, E.⁸ Putnam, A.J.⁹ Botvinick, E.L.¹⁰

80
- 80052266986
- C. Cha, J. H. Jeong, J. Shim, H. Kong, Acta Biomater. 2011, 7, 3719.
- (2011) Acta Biomater. , vol.7 , pp. 3719
- Cha, C.¹ Jeong, J.H.² Shim, J.³ Kong, H.⁴

81
- 84870237106
- B. N. Mason, A. Starchenko, R. M. Williams, L. J. Bonassar, C. A. Reinhart-King, Acta Biomater. 2013, 9, 4635.
- (2013) Acta Biomater. , vol.9 , pp. 4635
- Mason, B.N.¹ Starchenko, A.² Williams, R.M.³ Bonassar, L.J.⁴ Reinhart-King, C.A.⁵

82
- 80053603679
- Y. Liang, J. Jeong, R. J. DeVolder, C. Cha, F. Wang, Y. W. Tong, H. Kong, Biomaterials 2011, 32, 9308.
- (2011) Biomaterials , vol.32 , pp. 9308
- Liang, Y.¹ Jeong, J.² Devolder, R.J.³ Cha, C.⁴ Wang, F.⁵ Tong, Y.W.⁶ Kong, H.⁷

83
- 70450222098
- K. R. Levental, H. Yu, L. Kass, J. N. Lakins, M. Egeblad, J. T. Erler, S. F. Fong, K. Csiszar, A. Giaccia, W. Weninger, Cell 2009, 139, 891.
- (2009) Cell , vol.139 , pp. 891
- Levental, K.R.¹ Yu, H.² Kass, L.³ Lakins, J.N.⁴ Egeblad, M.⁵ Erler, J.T.⁶ Fong, S.F.⁷ Csiszar, K.⁸ Giaccia, A.⁹ Weninger, W.¹⁰

84
- 80052325855
- S. F. Lan, B. Starly, Toxicol. Appl. Pharmacol. 2011, 256, 62.
- (2011) Toxicol. Appl. Pharmacol. , vol.256 , pp. 62
- Lan, S.F.¹ Starly, B.²

85
- 69249230753
- L. A. Gurski, A. K. Jha, C. Zhang, X. Jia, M. C. Farach-Carson, Biomaterials 2009, 30, 6076.
- (2009) Biomaterials , vol.30 , pp. 6076
- Gurski, L.A.¹ Jha, A.K.² Zhang, C.³ Jia, X.⁴ Farach-Carson, M.C.⁵

86
- 84903973472
- C. R. Lam, H. K. Wong, S. Nai, C. K. Chua, N. S. Tan, L. P. Tan, Mol. Pharm. 2014, 11.
- (2014) Mol. Pharm. , vol.11
- Lam, C.R.¹ Wong, H.K.² Nai, S.³ Chua, C.K.⁴ Tan, N.S.⁵ Tan, L.P.⁶

87
- 84902667413
- G. Fernandez-Fuente, P. Mollinedo, L. Grande, A. Vazquez-Barquero, J. L. Fernandez-Luna, Mol. Cancer Ther. 2014, 13, 1664.
- (2014) Mol. Cancer Ther. , vol.13 , pp. 1664
- Fernandez-Fuente, G.¹ Mollinedo, P.² Grande, L.³ Vazquez-Barquero, A.⁴ Fernandez-Luna, J.L.⁵

88
- 78650845707
- R. Lappano, M. Maggiolini, Nat. Rev. Drug Discov. 2011, 10, 47.
- (2011) Nat. Rev. Drug Discov. , vol.10 , pp. 47
- Lappano, R.¹ Maggiolini, M.²

89
- 77956178360
- A. Singh, J. Settleman, Oncogene 2010, 29, 4741.
- (2010) Oncogene , vol.29 , pp. 4741
- Singh, A.¹ Settleman, J.²

90
- 84929085864
- DOI: 10.1002/bab.1302
- C. Liu, Y. Liu, H. G. Xie, S. Zhao, X. X. Xu, L. X. Fan, X. Guo, T. Lu, G. W. Sun, X. J. Ma, Biotechnol. Appl. Biochem. 2014, DOI: 10.1002/bab.1302
- (2014) Biotechnol. Appl. Biochem.
- Liu, C.¹ Liu, Y.² Xie, H.G.³ Zhao, S.⁴ Xu, X.X.⁵ Fan, L.X.⁶ Guo, X.⁷ Lu, T.⁸ Sun, G.W.⁹ Ma, X.J.¹⁰

91
- 79953670987
- A. Pathak, S. Kumar, Integrat. Biol. 2011, 3, 267.
- (2011) Integrat. Biol. , vol.3 , pp. 267
- Pathak, A.¹ Kumar, S.²

92
- 33746851956
- P. S. Steeg, Nat. Med. 2006, 12, 895.
- (2006) Nat. Med. , vol.12 , pp. 895
- Steeg, P.S.¹

93
- 84929069587
- Atlanta, GA
- K. Ramamoorthi, Y. Chehreghanianzabi, S. Zustiak, P. Asuri, AIChE Annual Meeting Conference Proceedings, Atlanta, GA, 112b, 2014.
- (2014) AIChE Annual Meeting Conference Proceedings , pp. 112b
- Ramamoorthi, K.¹ Chehreghanianzabi, Y.² Zustiak, S.³ Asuri, P.⁴

94
- 0036176510
- M. M. Gottesman, Ann. Rev. Med. 2002, 53, 615.
- (2002) Ann. Rev. Med. , vol.53 , pp. 615
- Gottesman, M.M.¹

95
- 0034680167
- C. Walsh, Nature 2000, 406, 775.
- (2000) Nature , vol.406 , pp. 775
- Walsh, C.¹

96
- 33646568511
- T. Ozben, FEBS Lett. 2006, 580, 2903.
- (2006) FEBS Lett. , vol.580 , pp. 2903
- Ozben, T.¹

97
- 13644254794
- D. Longley, P. Johnston, J. Pathol. 2005, 205, 275.
- (2005) J. Pathol. , vol.205 , pp. 275
- Longley, D.¹ Johnston, P.²

98
- 84884535896
- C. Holohan, S. Van Schaeybroeck, D. B. Longley, P. G. Johnston, Nat. Rev. Cancer 2013, 13, 714.
- (2013) Nat. Rev. Cancer , vol.13 , pp. 714
- Holohan, C.¹ Van Schaeybroeck, S.² Longley, D.B.³ Johnston, P.G.⁴

99
- 84905513547
- M. Ivanov, I. Barragan, M. Ingelman-Sundberg, Trends Pharmacol. Sci. 2014, 35, 384.
- (2014) Trends Pharmacol. Sci. , vol.35 , pp. 384
- Ivanov, M.¹ Barragan, I.² Ingelman-Sundberg, M.³

100
- 84924402378
- DOI: 10.1002/adhm.201400410
- J. Lam, S. T. Carmichael, W. E. Lowry, T. Segura, Adv. Healthcare Mater. 2015, DOI: 10.1002/adhm.201400410
- (2015) Adv. Healthcare Mater.
- Lam, J.¹ Carmichael, S.T.² Lowry, W.E.³ Segura, T.⁴

101
- 84864258391
- A. A. Cheng, T. K. Lu, Ann. Rev. Biomed. Eng. 2012, 14, 155.
- (2012) Ann. Rev. Biomed. Eng. , vol.14 , pp. 155
- Cheng, A.A.¹ Lu, T.K.²

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.