Developments in three-dimensional cell culture technology aimed at improving the accuracy of in vitro analyses

Biochemical Society Transactions

Volumn 38, Issue 4, 2010, Pages 1072-1075

  Maltman, Daniel J ^a,b   Przyborski, Stefan A ^a,b  

^a DURHAM UNIVERSITY   (United Kingdom)

^b ReproCELL Inc   (Japan)

Author keywords

Cell culture; Drug discovery; In vitro model; Polystyrene scaffold; Three dimensional cell culture

Indexed keywords

POLYGLACTIN; POLYGLYCOLIC ACID; POLYLACTIC ACID; POLYSTYRENE;

ACCURACY; BIODEGRADABILITY; CELL CULTURE; CELL DIFFERENTIATION; CELL GROWTH; CELL PROLIFERATION; CULTURE TECHNIQUE; HUMAN; HYDROGEL; IN VITRO STUDY; PRIORITY JOURNAL; REVIEW; STEM CELL; STEM CELL EXPANSION;

ANIMALS; CELL CULTURE TECHNIQUES; CELL PROLIFERATION; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; REPRODUCIBILITY OF RESULTS; STEM CELLS; TISSUE ENGINEERING; TISSUE SCAFFOLDS;

EID: 77955968267     PISSN: 03005127     EISSN: 14708752     Source Type: Journal    
DOI: 10.1042/BST0381072     Document Type: Review

References (25)

1. Bhadriraju, K. and Chen, C.S. (2002) Engineering cellular microenvironments to improve cell-based drug testing. Drug Discov. Today 7, 612-620
2. Schmeichel, K.L. and Bissell, M.J. (2003) Modeling tissue-specific signaling and organ function in three dimensions. J. Cell Sci. 116, 2377-2388
3. Sun, T., Jackson, S., Haycock, J.W. and MacNeil, S. (2006) Culture of skin cells in 3D rather than 2D improves their ability to survive exposure to cytotoxic agents. J. Biotechnol. 122, 372-381
4. Zimmermann, H., Shirley, S.G. and Zimmermann, U. (2007) Alginate-based encapsulation of cells: past, present, and future. Curr. Diabetes Rep. 7, 314-320
5. Dvir-Ginzberg, M., Elkayam, T. and Cohen, S. (2008) Induced differentiation and maturation of newborn liver cells into functional hepatic tissue in macroporous alginate scaffolds. FASEB J. 22, 1440-1449
6. Mikos, A.G., Sarakinos, G., Leite, S.M., Vacanti, J.P. and Langer, R. (1993) Laminated three-dimensional biodegradable foams for use in tissue engineering. Biomaterials 14, 323-330
7. Temenoff, J.S. and Mikos, A.G. (2000) Injectable biodegradable materials for orthopedic tissue engineering. Biomaterials 21, 2405-2412
8. Blackshaw, S.E., Arkison, S., Cameron, C. and Davies, J.A. (1997) Promotion of regeneration and axon growth following injury in an invertebrate nervous system by the use of three-dimensional collagen gels. Proc. Biol. Sci. 264, 657-661
9. Fisher, J.P., Jo, S., Mikos, A.G. and Reddi, A.H. (2004) Thermoreversible hydrogel scaffolds for articular cartilage engineering. J. Biomed. Mater. Res. A 71, 268-274
10. Park, Y., Sugimoto, M., Watrin, A., Chiquet, M. and Hunziker, E.B. (2005) BMP-2 induces the expression of chondrocyte-specific genes in bovine synovium-derived progenitor cells cultured in three-dimensional alginate hydrogel. Osteoarthritis Cartilage 13, 527-536
11. Sakiyama, S.E., Schense, J.C. and Hubbell, J.A. (1999) Incorporation of heparin-binding peptides into fibrin gels enhances neurite extension: an example of designer matrices in tissue engineering. FASEB J. 13, 2214-2224
12. Yu, X., Dillon, G.P. and Bellamkonda, R.B. (1999) A laminin and nerve growth factor-laden three-dimensional scaffold for enhanced neurite extension. Tissue Eng. 5, 291-304
13. Dillon, G.P., Yu, X., Sridharan, A., Ranieri, J.P. and Bellamkonda, R.V. (1998) The influence of physical structure and charge on neurite extension in a 3D hydrogel scaffold. J. Biomater. Sci. Polym. Ed. 9, 1049-1069
14. Bokhari, M., Carnachan, R.J., Przyborski, S.A. and Cameron, N.R. (2007) Emulsion-templated porous polymers as scaffolds for three dimensional cell culture: effect of synthesis parameters on scaffold formation and homogeneity. J. Mater. Chem. 17, 4088-4094
15. Carnachan, R.J., Bokhari, M., Przyborski, S.A. and Cameron, N.R. (2006) Tailoring the morphology of emulsion-templated porous polymers. Soft Matter 2, 608-616
16. Aydin, H.M., El Haj, A.J., Piskin, E. and Yang, Y. (2009) Improving pore interconnectivity in polymeric scaffolds for tissue engineering. J. Tissue Eng. Regen. Med. 3, 470-476
17. Salerno, A., Oliviero, M., Di Maio, E., Iannace, S. and Netti, P.A. (2009) Design of porous polymeric scaffolds by gas foaming of heterogeneous blends. J. Mater. Sci. Mater. Med. 20, 2043-2051
18. Barbetta, A., Gumiero, A., Pecci, R., Bedini, R. and Dentini, M. (2009) Gas-in-liquid foam templating as a method for the production of highly porous scaffolds. Biomacromolecules 10, 3188-3192
19. Sun, T., Norton, D., McKean, R.J., Haycock, J.W., Ryan, A.J. and MacNeil, S. (2007) Development of a 3D cell culture system for investigating cell interactions with electrospun fibers. Biotechnol. Bioeng. 97, 1318-1328
20. Barbetta, A., Cameron, N.R. and Cooper, S.J. (2000) High internal phase emulsions (HIPEs) containing divinylbenzene and 4-vinylbenzyl chloride and the morphology of the resulting PolyHIPE materials, Chem. Commun., 221-222
21. Dash, A., Inman, W., Hoffmaster, K., Sevidal, S., Kelly, J., Obach, R.S., Griffith, L.G. and Tannenbaum, S.R. (2009) Liver tissue engineering in the evaluation of drug safety. Exp. Opin. Drug Metab. Toxicol. 5, 1159-1174
22. Bokhari, M., Carnachan, R.J., Cameron, N.R. and Przyborski, S.A. (2007) Culture of HepG2 liver cells on three dimensional polystyrene scaffolds enhances cell structure and function during toxicological challenge. J. Anat. 211, 567-576
23. Bokhari, M., Carnachan, R.J., Cameron, N.R. and Przyborski, S.A. (2007) Novel cell culture device enabling three-dimensional cell growth and improved cell function. Biochem. Biophys. Res. Commun. 354, 1095-1100
24. Ochiya, T., Yamamoto, Y. and Banas, A. (2010) Commitment of stem cells into functional hepatocytes. Differentiation 79, 65-73
25. Safinia, N. and Minger, S.L. (2009) Generation of hepatocytes from human embryonic stem cells. Methods Mol. Biol. 481, 169-180