PIM kinases in hematological malignancies: Where are we now and where are we going?

Journal of Hematology and Oncology

Volumn 7, Issue 1, 2014, Pages

  Mondello, Patrizia ^a   Cuzzocrea, Salvatore ^a   Mian, Michael ^b,c  

^a UNIVERSITY OF MESSINA   (Italy)

^b Hospital S Maurizio   (Italy)

^c INNSBRUCK MEDICAL UNIVERSITY   (Austria)

Author keywords

Hematologic malignancies; Pim inhibitors; Pim kinases; Target therapy

Indexed keywords

3 AMINO PIPERIDINE PYRIDYL CARBOXAMIDE; ANTINEOPLASTIC AGENT; AZD 1208; AZD 1897; BENZYLIDENE THIAZOLIDENE 2,4 DIONE; ENZYME INHIBITOR; LGB 321; PIM KINASE INHIBITOR; PROTEIN KINASE PIM 1; PROTEIN KINASE PIM 2; PROTEIN KINASE PIM 3; PROTEIN SERINE THREONINE KINASE; PYRIDAZINE DERIVATIVE; RAPAMYCIN; SEL 24B 58; SGI 1776; SMI 4A; UNCLASSIFIED DRUG;

ACUTE MYELOBLASTIC LEUKEMIA; APOPTOSIS; CANCER CHEMOTHERAPY; CARCINOGENESIS; CARDIOTOXICITY; CELL CYCLE REGULATION; CELL MIGRATION; CELL PROLIFERATION; CLINICAL TRIAL (TOPIC); DRUG TARGETING; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HEMATOLOGIC MALIGNANCY; HUMAN; LYMPHOMA; MOLECULARLY TARGETED THERAPY; MULTIPLE MYELOMA; NONHODGKIN LYMPHOMA; NONHUMAN; PHASE 1 CLINICAL TRIAL (TOPIC); PROTEIN EXPRESSION; REVIEW; TUMOR GROWTH;

EID: 84928692826     PISSN: None     EISSN: 17568722     Source Type: Journal    
DOI: 10.1186/s13045-014-0095-z     Document Type: Review

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