-
1
-
-
70350433490
-
Mitochondrial integrity: preservation through Akt/Pim-1 kinase signaling in the cardiomyocyte
-
Sussman M.A. Mitochondrial integrity: preservation through Akt/Pim-1 kinase signaling in the cardiomyocyte. Expert Rev Cardiovasc Ther 2009 Aug, 7(8):929-938.
-
(2009)
Expert Rev Cardiovasc Ther
, vol.7
, Issue.8
, pp. 929-938
-
-
Sussman, M.A.1
-
2
-
-
67449156064
-
Nuclear and mitochondrial signalling Akts in cardiomyocytes
-
Miyamoto S., Rubio M., Sussman M.A. Nuclear and mitochondrial signalling Akts in cardiomyocytes. Cardiovasc Res 2009 May 1, 82(2):272-285.
-
(2009)
Cardiovasc Res
, vol.82
, Issue.2
, pp. 272-285
-
-
Miyamoto, S.1
Rubio, M.2
Sussman, M.A.3
-
3
-
-
0021233675
-
Murine leukemia virus-induced T-cell lymphomagenesis: integration of proviruses in a distinct chromosomal region
-
Cuypers H.T., Selten G., Quint W., Zijlstra M., Maandag E.R., Boelens W., et al. Murine leukemia virus-induced T-cell lymphomagenesis: integration of proviruses in a distinct chromosomal region. Cell 1984 May, 37(1):141-150.
-
(1984)
Cell
, vol.37
, Issue.1
, pp. 141-150
-
-
Cuypers, H.T.1
Selten, G.2
Quint, W.3
Zijlstra, M.4
Maandag, E.R.5
Boelens, W.6
-
4
-
-
2942700011
-
Mice deficient for all PIM kinases display reduced body size and impaired responses to hematopoietic growth factors
-
Mikkers H., Nawijn M., Allen J., Brouwers C., Verhoeven E., Jonkers J., et al. Mice deficient for all PIM kinases display reduced body size and impaired responses to hematopoietic growth factors. Mol Cell Biol 2004 Jul, 24(13):6104-6115.
-
(2004)
Mol Cell Biol
, vol.24
, Issue.13
, pp. 6104-6115
-
-
Mikkers, H.1
Nawijn, M.2
Allen, J.3
Brouwers, C.4
Verhoeven, E.5
Jonkers, J.6
-
5
-
-
0025806308
-
The human PIM-1 gene product is a protein serine kinase
-
Padma R., Nagarajan L. The human PIM-1 gene product is a protein serine kinase. Cancer Res 1991 May 1, 51(9):2486-2489.
-
(1991)
Cancer Res
, vol.51
, Issue.9
, pp. 2486-2489
-
-
Padma, R.1
Nagarajan, L.2
-
6
-
-
0030932844
-
Identification of the autophosphorylation sites of the Xenopus laevis Pim-1 proto-oncogene-encoded protein kinase
-
Palaty C.K., Kalmar G., Tai G., Oh S., Amankawa L., Affolter M., et al. Identification of the autophosphorylation sites of the Xenopus laevis Pim-1 proto-oncogene-encoded protein kinase. J Biol Chem 1997 Apr 18, 272(16):10514-10521.
-
(1997)
J Biol Chem
, vol.272
, Issue.16
, pp. 10514-10521
-
-
Palaty, C.K.1
Kalmar, G.2
Tai, G.3
Oh, S.4
Amankawa, L.5
Affolter, M.6
-
7
-
-
20044379405
-
Structural basis of constitutive activity and a unique nucleotide binding mode of human Pim-1 kinase
-
Qian K.C., Wang L., Hickey E.R., Studts J., Barringer K., Peng C., et al. Structural basis of constitutive activity and a unique nucleotide binding mode of human Pim-1 kinase. J Biol Chem 2005 Feb 18, 280(7):6130-6137.
-
(2005)
J Biol Chem
, vol.280
, Issue.7
, pp. 6130-6137
-
-
Qian, K.C.1
Wang, L.2
Hickey, E.R.3
Studts, J.4
Barringer, K.5
Peng, C.6
-
8
-
-
13444251304
-
The serine/threonine kinase Pim-1
-
Bachmann M., Moroy T. The serine/threonine kinase Pim-1. Int J Biochem Cell Biol 2005 Apr, 37(4):726-730.
-
(2005)
Int J Biochem Cell Biol
, vol.37
, Issue.4
, pp. 726-730
-
-
Bachmann, M.1
Moroy, T.2
-
9
-
-
26444448463
-
The survival kinases Akt and Pim as potential pharmacological targets
-
Amaravadi R., Thompson C.B. The survival kinases Akt and Pim as potential pharmacological targets. J Clin Invest 2005 Oct, 115(10):2618-2624.
-
(2005)
J Clin Invest
, vol.115
, Issue.10
, pp. 2618-2624
-
-
Amaravadi, R.1
Thompson, C.B.2
-
11
-
-
0025073090
-
Rearrangements of the Pim-1, c-myc, and p53 genes in Friend helper virus-induced mouse erythroleukemias
-
Dreyfus F., Sola B., Fichelson S., Varlet P., Charon M., Tambourin P., et al. Rearrangements of the Pim-1, c-myc, and p53 genes in Friend helper virus-induced mouse erythroleukemias. Leukemia 1990 Aug, 4(8):590-594.
-
(1990)
Leukemia
, vol.4
, Issue.8
, pp. 590-594
-
-
Dreyfus, F.1
Sola, B.2
Fichelson, S.3
Varlet, P.4
Charon, M.5
Tambourin, P.6
-
12
-
-
77949319044
-
A small molecule inhibitor of Pim protein kinases blocks the growth of precursor T-cell lymphoblastic leukemia/lymphoma
-
Jan 28
-
Lin YW, Beharry ZM, Hill EG, Song JH, Wang W, Xia Z, et al. A small molecule inhibitor of Pim protein kinases blocks the growth of precursor T-cell lymphoblastic leukemia/lymphoma. Blood. Jan 28; 115(4): 824-33.
-
Blood.
, vol.115
, Issue.4
, pp. 824-33
-
-
Lin, Y.W.1
Beharry, Z.M.2
Hill, E.G.3
Song, J.H.4
Wang, W.5
Xia, Z.6
-
13
-
-
52049122136
-
Isoxazolo[3, 4-b]quinoline-3, 4(1H, 9)-diones as unique, potent and selective inhibitors for Pim-1 and Pim-2 kinases: chemistry, biological activities, and molecular modeling
-
Tong Y., Stewart K.D., Thomas S., Przytulinska M., Johnson E.F., Klinghofer V., et al. Isoxazolo[3, 4-b]quinoline-3, 4(1H, 9)-diones as unique, potent and selective inhibitors for Pim-1 and Pim-2 kinases: chemistry, biological activities, and molecular modeling. Bioorg Med Chem Lett 2008 Oct 1, 18(19):5206-5208.
-
(2008)
Bioorg Med Chem Lett
, vol.18
, Issue.19
, pp. 5206-5208
-
-
Tong, Y.1
Stewart, K.D.2
Thomas, S.3
Przytulinska, M.4
Johnson, E.F.5
Klinghofer, V.6
-
14
-
-
0034708236
-
Developmental expression of pim kinases suggests functions also outside of the hematopoietic system
-
Eichmann A., Yuan L., Breant C., Alitalo K., Koskinen P.J. Developmental expression of pim kinases suggests functions also outside of the hematopoietic system. Oncogene 2000 Feb 24, 19(9):1215-1224.
-
(2000)
Oncogene
, vol.19
, Issue.9
, pp. 1215-1224
-
-
Eichmann, A.1
Yuan, L.2
Breant, C.3
Alitalo, K.4
Koskinen, P.J.5
-
15
-
-
0035754569
-
Pim-1: a serine/threonine kinase with a role in cell survival, proliferation, differentiation and tumorigenesis
-
Wang Z., Bhattacharya N., Weaver M., Petersen K., Meyer M., Gapter L., et al. Pim-1: a serine/threonine kinase with a role in cell survival, proliferation, differentiation and tumorigenesis. J Vet Sci 2001 Dec, 2(3):167-179.
-
(2001)
J Vet Sci
, vol.2
, Issue.3
, pp. 167-179
-
-
Wang, Z.1
Bhattacharya, N.2
Weaver, M.3
Petersen, K.4
Meyer, M.5
Gapter, L.6
-
16
-
-
0036847027
-
The Src family kinase Hck couples BCR/ABL to STAT5 activation in myeloid leukemia cells
-
Klejman A., Schreiner S.J., Nieborowska-Skorska M., Slupianek A., Wilson M., Smithgall T.E., et al. The Src family kinase Hck couples BCR/ABL to STAT5 activation in myeloid leukemia cells. EMBO J 2002 Nov 1, 21(21):5766-5774.
-
(2002)
EMBO J
, vol.21
, Issue.21
, pp. 5766-5774
-
-
Klejman, A.1
Schreiner, S.J.2
Nieborowska-Skorska, M.3
Slupianek, A.4
Wilson, M.5
Smithgall, T.E.6
-
17
-
-
0024595556
-
Predisposition to lymphomagenesis in pim-1 transgenic mice: cooperation with c-myc and N-myc in murine leukemia virus-induced tumors
-
van Lohuizen M., Verbeek S., Krimpenfort P., Domen J., Saris C., Radaszkiewicz T., et al. Predisposition to lymphomagenesis in pim-1 transgenic mice: cooperation with c-myc and N-myc in murine leukemia virus-induced tumors. Cell 1989 Feb 24, 56(4):673-682.
-
(1989)
Cell
, vol.56
, Issue.4
, pp. 673-682
-
-
van Lohuizen, M.1
Verbeek, S.2
Krimpenfort, P.3
Domen, J.4
Saris, C.5
Radaszkiewicz, T.6
-
18
-
-
0025863346
-
Identification of cooperating oncogenes in E mu-myc transgenic mice by provirus tagging
-
van Lohuizen M., Verbeek S., Scheijen B., Wientjens E., van der Gulden H., Berns A. Identification of cooperating oncogenes in E mu-myc transgenic mice by provirus tagging. Cell 1991 May 31, 65(5):737-752.
-
(1991)
Cell
, vol.65
, Issue.5
, pp. 737-752
-
-
van Lohuizen, M.1
Verbeek, S.2
Scheijen, B.3
Wientjens, E.4
van der Gulden, H.5
Berns, A.6
-
19
-
-
0024408829
-
The human protooncogene product p33pim is expressed during fetal hematopoiesis and in diverse leukemias
-
Amson R., Sigaux F., Przedborski S., Flandrin G., Givol D., Telerman A. The human protooncogene product p33pim is expressed during fetal hematopoiesis and in diverse leukemias. Proc Natl Acad Sci USA 1989 Nov, 86(22):8857-8861.
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, Issue.22
, pp. 8857-8861
-
-
Amson, R.1
Sigaux, F.2
Przedborski, S.3
Flandrin, G.4
Givol, D.5
Telerman, A.6
-
20
-
-
36849037512
-
Pim-1 regulates cardiomyocyte survival downstream of Akt
-
Muraski J.A., Rota M., Misao Y., Fransioli J., Cottage C., Gude N., et al. Pim-1 regulates cardiomyocyte survival downstream of Akt. Nat Med 2007 Dec, 13(12):1467-1475.
-
(2007)
Nat Med
, vol.13
, Issue.12
, pp. 1467-1475
-
-
Muraski, J.A.1
Rota, M.2
Misao, Y.3
Fransioli, J.4
Cottage, C.5
Gude, N.6
-
21
-
-
0345268731
-
Pim-1 protein kinase is nuclear in Burkitt's lymphoma: nuclear localization is necessary for its biologic effects
-
Ionov Y., Le X., Tunquist B.J., Sweetenham J., Sachs T., Ryder J., et al. Pim-1 protein kinase is nuclear in Burkitt's lymphoma: nuclear localization is necessary for its biologic effects. Anticancer Res 2003 Jan-Feb, 23(1A):167-178.
-
Anticancer Res
-
-
Ionov, Y.1
Le, X.2
Tunquist, B.J.3
Sweetenham, J.4
Sachs, T.5
Ryder, J.6
-
22
-
-
77951299101
-
Pim-1 kinase protects mitochondrial integrity in cardiomyocytes
-
Apr 16
-
Borillo GA, Mason M, Quijada P, Volkers M, Cottage C, McGregor M, et al. Pim-1 kinase protects mitochondrial integrity in cardiomyocytes. Circ Res. Apr 16; 106(7): 1265-74.
-
Circ Res.
, vol.106
, Issue.7
, pp. 1265-74
-
-
Borillo, G.A.1
Mason, M.2
Quijada, P.3
Volkers, M.4
Cottage, C.5
McGregor, M.6
-
23
-
-
77950877955
-
Cardiac progenitor cell cycling stimulated by pim-1 kinase
-
Mar 19
-
Cottage CT, Bailey B, Fischer KM, Avitable D, Collins B, Tuck S, et al. Cardiac progenitor cell cycling stimulated by pim-1 kinase. Circ Res. Mar 19; 106(5): 891-901.
-
Circ Res.
, vol.106
, Issue.5
, pp. 891-901
-
-
Cottage, C.T.1
Bailey, B.2
Fischer, K.M.3
Avitable, D.4
Collins, B.5
Tuck, S.6
-
24
-
-
73449130151
-
Enhancement of myocardial regeneration through genetic engineering of cardiac progenitor cells expressing Pim-1 kinase
-
Fischer K.M., Cottage C.T., Wu W., Din S., Gude N.A., Avitabile D., et al. Enhancement of myocardial regeneration through genetic engineering of cardiac progenitor cells expressing Pim-1 kinase. Circulation 2009, 120(21):2077-2087.
-
(2009)
Circulation
, vol.120
, Issue.21
, pp. 2077-2087
-
-
Fischer, K.M.1
Cottage, C.T.2
Wu, W.3
Din, S.4
Gude, N.A.5
Avitabile, D.6
-
25
-
-
52949116043
-
Pim-1 kinase antagonizes aspects of myocardial hypertrophy and compensation to pathological pressure overload
-
Muraski J.A., Fischer K.M., Wu W., Cottage C.T., Quijada P., Mason M., et al. Pim-1 kinase antagonizes aspects of myocardial hypertrophy and compensation to pathological pressure overload. Proc Natl Acad Sci USA 2008, 105(37):13889-13894.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, Issue.37
, pp. 13889-13894
-
-
Muraski, J.A.1
Fischer, K.M.2
Wu, W.3
Cottage, C.T.4
Quijada, P.5
Mason, M.6
-
26
-
-
77950343957
-
Transcriptional regulation of Pim-1 kinase in vascular smooth muscle cells and its role for proliferation
-
Mar
-
Willert M, Augstein A, Poitz DM, Schmeisser A, Strasser RH, Braun-Dullaeus RC. Transcriptional regulation of Pim-1 kinase in vascular smooth muscle cells and its role for proliferation. Basic Res Cardiol. Mar; 105(2): 267-77.
-
Basic Res Cardiol.
, vol.105
, Issue.2
, pp. 267-77
-
-
Willert, M.1
Augstein, A.2
Poitz, D.M.3
Schmeisser, A.4
Strasser, R.H.5
Braun-Dullaeus, R.C.6
-
27
-
-
0036664907
-
Pim-1 associates with protein complexes necessary for mitosis
-
Bhattacharya N., Wang Z., Davitt C., McKenzie I.F., Xing P.X., Magnuson N.S. Pim-1 associates with protein complexes necessary for mitosis. Chromosoma 2002, 111(2):80-95.
-
(2002)
Chromosoma
, vol.111
, Issue.2
, pp. 80-95
-
-
Bhattacharya, N.1
Wang, Z.2
Davitt, C.3
McKenzie, I.F.4
Xing, P.X.5
Magnuson, N.S.6
-
28
-
-
2942525073
-
Identification of Flk-1 target genes in vasculogenesis: Pim-1 is required for endothelial and mural cell differentiation in vitro
-
Zippo A., De Robertis A., Bardelli M., Galvagni F., Oliviero S. Identification of Flk-1 target genes in vasculogenesis: Pim-1 is required for endothelial and mural cell differentiation in vitro. Blood 2004, 103(12):4536-4544.
-
(2004)
Blood
, vol.103
, Issue.12
, pp. 4536-4544
-
-
Zippo, A.1
De Robertis, A.2
Bardelli, M.3
Galvagni, F.4
Oliviero, S.5
-
29
-
-
30044433786
-
The 44kDa Pim-1 kinase directly interacts with tyrosine kinase Etk/BMX and protects human prostate cancer cells from apoptosis induced by chemotherapeutic drugs
-
Xie Y., Xu K., Dai B., Guo Z., Jiang T., Chen H., et al. The 44kDa Pim-1 kinase directly interacts with tyrosine kinase Etk/BMX and protects human prostate cancer cells from apoptosis induced by chemotherapeutic drugs. Oncogene 2006, 25(1):70-78.
-
(2006)
Oncogene
, vol.25
, Issue.1
, pp. 70-78
-
-
Xie, Y.1
Xu, K.2
Dai, B.3
Guo, Z.4
Jiang, T.5
Chen, H.6
-
30
-
-
75649112672
-
Cardiac stem cell genetic engineering using the alphaMHC promoter
-
Bailey B., Izarra A., Alvarez R., Fischer K.M., Cottage C.T., Quijada P., et al. Cardiac stem cell genetic engineering using the alphaMHC promoter. Regen Med 2009, 4(6):823-833.
-
(2009)
Regen Med
, vol.4
, Issue.6
, pp. 823-833
-
-
Bailey, B.1
Izarra, A.2
Alvarez, R.3
Fischer, K.M.4
Cottage, C.T.5
Quijada, P.6
-
31
-
-
34547642807
-
Negative regulation of Pim-1 protein kinase levels by the B56beta subunit of PP2A
-
Ma J., Arnold H.K., Lilly M.B., Sears R.C., Kraft A.S. Negative regulation of Pim-1 protein kinase levels by the B56beta subunit of PP2A. Oncogene 2007, 26(35):5145-5153.
-
(2007)
Oncogene
, vol.26
, Issue.35
, pp. 5145-5153
-
-
Ma, J.1
Arnold, H.K.2
Lilly, M.B.3
Sears, R.C.4
Kraft, A.S.5
-
32
-
-
0032531041
-
Evidence implicating Gfi-1 and Pim-1 in pre-T-cell differentiation steps associated with beta-selection
-
Schmidt T., Karsunky H., Rodel B., Zevnik B., Elsasser H.P., Moroy T. Evidence implicating Gfi-1 and Pim-1 in pre-T-cell differentiation steps associated with beta-selection. EMBO J 1998, 17(18):5349-5359.
-
(1998)
EMBO J
, vol.17
, Issue.18
, pp. 5349-5359
-
-
Schmidt, T.1
Karsunky, H.2
Rodel, B.3
Zevnik, B.4
Elsasser, H.P.5
Moroy, T.6
-
33
-
-
0033536203
-
The PIM-1 serine kinase prolongs survival and inhibits apoptosis-related mitochondrial dysfunction in part through a bcl-2-dependent pathway
-
Lilly M., Sandholm J., Cooper J.J., Koskinen P.J., Kraft A. The PIM-1 serine kinase prolongs survival and inhibits apoptosis-related mitochondrial dysfunction in part through a bcl-2-dependent pathway. Oncogene 1999, 18(27):4022-4031.
-
(1999)
Oncogene
, vol.18
, Issue.27
, pp. 4022-4031
-
-
Lilly, M.1
Sandholm, J.2
Cooper, J.J.3
Koskinen, P.J.4
Kraft, A.5
-
34
-
-
29244464759
-
The oncogenic serine/threonine kinase Pim-1 directly phosphorylates and activates the G2/M specific phosphatase Cdc25C
-
Bachmann M., Kosan C., Xing P.X., Montenarh M., Hoffmann I., Moroy T. The oncogenic serine/threonine kinase Pim-1 directly phosphorylates and activates the G2/M specific phosphatase Cdc25C. Int J Biochem Cell Biol 2006, 38(3):430-443.
-
(2006)
Int J Biochem Cell Biol
, vol.38
, Issue.3
, pp. 430-443
-
-
Bachmann, M.1
Kosan, C.2
Xing, P.X.3
Montenarh, M.4
Hoffmann, I.5
Moroy, T.6
-
35
-
-
0033603454
-
Physical and functional interactions between Pim-1 kinase and Cdc25A phosphatase. Implications for the Pim-1-mediated activation of the c-Myc signaling pathway
-
Mochizuki T., Kitanaka C., Noguchi K., Muramatsu T., Asai A., Kuchino Y. Physical and functional interactions between Pim-1 kinase and Cdc25A phosphatase. Implications for the Pim-1-mediated activation of the c-Myc signaling pathway. J Biol Chem 1999, 274(26):18659-18666.
-
(1999)
J Biol Chem
, vol.274
, Issue.26
, pp. 18659-18666
-
-
Mochizuki, T.1
Kitanaka, C.2
Noguchi, K.3
Muramatsu, T.4
Asai, A.5
Kuchino, Y.6
-
36
-
-
0037121534
-
Phosphorylation of the cell cycle inhibitor p21Cip1/WAF1 by Pim-1 kinase
-
Wang Z., Bhattacharya N., Mixter P.F., Wei W., Sedivy J., Magnuson N.S. Phosphorylation of the cell cycle inhibitor p21Cip1/WAF1 by Pim-1 kinase. Biochim Biophys Acta 2002, 1593(1):45-55.
-
(2002)
Biochim Biophys Acta
, vol.1593
, Issue.1
, pp. 45-55
-
-
Wang, Z.1
Bhattacharya, N.2
Mixter, P.F.3
Wei, W.4
Sedivy, J.5
Magnuson, N.S.6
-
37
-
-
0035821988
-
Evidence that human cardiac myocytes divide after myocardial infarction
-
Beltrami A.P., Urbanek K., Kajstura J., Yan S.M., Finato N., Bussani R., et al. Evidence that human cardiac myocytes divide after myocardial infarction. N Engl J Med 2001, 344(23):1750-1757.
-
(2001)
N Engl J Med
, vol.344
, Issue.23
, pp. 1750-1757
-
-
Beltrami, A.P.1
Urbanek, K.2
Kajstura, J.3
Yan, S.M.4
Finato, N.5
Bussani, R.6
-
38
-
-
67649969176
-
Hypoxia-mediated up-regulation of Pim-1 contributes to solid tumor formation
-
Chen J., Kobayashi M., Darmanin S., Qiao Y., Gully C., Zhao R., et al. Hypoxia-mediated up-regulation of Pim-1 contributes to solid tumor formation. Am J Pathol 2009, 175(1):400-411.
-
(2009)
Am J Pathol
, vol.175
, Issue.1
, pp. 400-411
-
-
Chen, J.1
Kobayashi, M.2
Darmanin, S.3
Qiao, Y.4
Gully, C.5
Zhao, R.6
|