메뉴 건너뛰기




Volumn 383, Issue 3, 2009, Pages 308-313

The juxtamembrane domain in ETV6/FLT3 is critical for PIM-1 up-regulation and cell proliferation

Author keywords

AKT; ETV6 FLT3; MAPK; PIM 1; STAT5

Indexed keywords

CD135 ANTIGEN; INTERLEUKIN 3; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; PROTEIN KINASE PIM 1; PROTEIN TYROSINE KINASE; STAT5 PROTEIN; TRANSCRIPTION FACTOR ETV6;

EID: 67349203576     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2009.03.157     Document Type: Article
Times cited : (9)

References (24)
  • 1
    • 0025998533 scopus 로고
    • A receptor tyrosine kinase cDNA isolated from a population of enriched primitive hematopoietic cells and exhibiting close genetic linkage to c-kit
    • Matthews W., Jordan C.T., Gavin M., Jenkins N.A., Copeland N.G., and Lemischka I.R. A receptor tyrosine kinase cDNA isolated from a population of enriched primitive hematopoietic cells and exhibiting close genetic linkage to c-kit. Proc. Natl. Acad. Sci. USA 88 (1991) 9026-9030
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 9026-9030
    • Matthews, W.1    Jordan, C.T.2    Gavin, M.3    Jenkins, N.A.4    Copeland, N.G.5    Lemischka, I.R.6
  • 2
    • 0025870946 scopus 로고
    • Murine Flt3, a gene encoding a novel tyrosine kinase receptor of the PDGFR/CSF1R family
    • Rosnet O., Marchetto S., deLapeyriere O., and Birnbaum D. Murine Flt3, a gene encoding a novel tyrosine kinase receptor of the PDGFR/CSF1R family. Oncogene 6 (1991) 1641-1650
    • (1991) Oncogene , vol.6 , pp. 1641-1650
    • Rosnet, O.1    Marchetto, S.2    deLapeyriere, O.3    Birnbaum, D.4
  • 4
    • 33748192963 scopus 로고    scopus 로고
    • Identification of Y589 and Y599 in the juxtamembrane domain of Flt3 as ligand-induced autophosphorylation sites involved in binding of Src family kinases and the protein tyrosine phosphatase SHP2
    • Heiss E., Masson K., Sundberg C., Pedersen M., Sun J., Bengtsson S., and Ronnstrand L. Identification of Y589 and Y599 in the juxtamembrane domain of Flt3 as ligand-induced autophosphorylation sites involved in binding of Src family kinases and the protein tyrosine phosphatase SHP2. Blood 108 (2006) 1542-1550
    • (2006) Blood , vol.108 , pp. 1542-1550
    • Heiss, E.1    Masson, K.2    Sundberg, C.3    Pedersen, M.4    Sun, J.5    Bengtsson, S.6    Ronnstrand, L.7
  • 6
    • 0141465061 scopus 로고    scopus 로고
    • The role of FLT3 in haematopoietic malignancies
    • Stirewalt D.L., and Radich J.P. The role of FLT3 in haematopoietic malignancies. Nat. Rev. Cancer 3 (2003) 650-665
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 650-665
    • Stirewalt, D.L.1    Radich, J.P.2
  • 8
    • 0035885955 scopus 로고    scopus 로고
    • The presence of a FLT3 internal tandem duplication in patients with acute myeloid leukemia (AML) adds important prognostic information to cytogenetic risk group and response to the first cycle of chemotherapy: analysis of 854 patients from the United Kingdom Medical Research Council AML 10 and 12 trials
    • Kottaridis P.D., Gale R.E., Frew M.E., Harrison G., Langabeer S.E., Belton A.A., Walker H., Wheatley K., Bowen D.T., Burnett A.K., Goldstone A.H., and Linch D.C. The presence of a FLT3 internal tandem duplication in patients with acute myeloid leukemia (AML) adds important prognostic information to cytogenetic risk group and response to the first cycle of chemotherapy: analysis of 854 patients from the United Kingdom Medical Research Council AML 10 and 12 trials. Blood 98 (2001) 1752-1759
    • (2001) Blood , vol.98 , pp. 1752-1759
    • Kottaridis, P.D.1    Gale, R.E.2    Frew, M.E.3    Harrison, G.4    Langabeer, S.E.5    Belton, A.A.6    Walker, H.7    Wheatley, K.8    Bowen, D.T.9    Burnett, A.K.10    Goldstone, A.H.11    Linch, D.C.12
  • 9
    • 0036659931 scopus 로고    scopus 로고
    • Analysis of FLT3 length mutations in 1003 patients with acute myeloid leukemia: correlation to cytogenetics, FAB subtype, and prognosis in the AMLCG study and usefulness as a marker for the detection of minimal residual disease
    • Schnittger S., Schoch C., Dugas M., Kern W., Staib P., Wuchter C., Loffler H., Sauerland C.M., Serve H., Buchner T., Haferlach T., and Hiddemann W. Analysis of FLT3 length mutations in 1003 patients with acute myeloid leukemia: correlation to cytogenetics, FAB subtype, and prognosis in the AMLCG study and usefulness as a marker for the detection of minimal residual disease. Blood 100 (2002) 59-66
    • (2002) Blood , vol.100 , pp. 59-66
    • Schnittger, S.1    Schoch, C.2    Dugas, M.3    Kern, W.4    Staib, P.5    Wuchter, C.6    Loffler, H.7    Sauerland, C.M.8    Serve, H.9    Buchner, T.10    Haferlach, T.11    Hiddemann, W.12
  • 10
    • 0037097716 scopus 로고    scopus 로고
    • Analysis of FLT3-activating mutations in 979 patients with acute myelogenous leukemia: association with FAB subtypes and identification of subgroups with poor prognosis
    • Thiede C., Steudel C., Mohr B., Schaich M., Schakel U., Platzbecker U., Wermke M., Bornhauser M., Ritter M., Neubauer A., Ehninger G., and Illmer T. Analysis of FLT3-activating mutations in 979 patients with acute myelogenous leukemia: association with FAB subtypes and identification of subgroups with poor prognosis. Blood 99 (2002) 4326-4335
    • (2002) Blood , vol.99 , pp. 4326-4335
    • Thiede, C.1    Steudel, C.2    Mohr, B.3    Schaich, M.4    Schakel, U.5    Platzbecker, U.6    Wermke, M.7    Bornhauser, M.8    Ritter, M.9    Neubauer, A.10    Ehninger, G.11    Illmer, T.12
  • 13
    • 33747189188 scopus 로고    scopus 로고
    • Roles of tyrosine 589 and 591 in STAT5 activation and transformation mediated by FLT3-ITD
    • Rocnik J.L., Okabe R., Yu J.C., Lee B.H., Giese N., Schenkein D.P., and Gilliland D.G. Roles of tyrosine 589 and 591 in STAT5 activation and transformation mediated by FLT3-ITD. Blood 108 (2006) 1339-1345
    • (2006) Blood , vol.108 , pp. 1339-1345
    • Rocnik, J.L.1    Okabe, R.2    Yu, J.C.3    Lee, B.H.4    Giese, N.5    Schenkein, D.P.6    Gilliland, D.G.7
  • 14
    • 18244362065 scopus 로고    scopus 로고
    • FLT3-ITD-TKD dual mutants associated with AML confer resistance to FLT3 PTK inhibitors and cytotoxic agents by overexpression of Bcl-x(L)
    • Bagrintseva K., Geisenhof S., Kern R., Eichenlaub S., Reindl C., Ellwart J.W., Hiddemann W., and Spiekermann K. FLT3-ITD-TKD dual mutants associated with AML confer resistance to FLT3 PTK inhibitors and cytotoxic agents by overexpression of Bcl-x(L). Blood 105 (2005) 3679-3685
    • (2005) Blood , vol.105 , pp. 3679-3685
    • Bagrintseva, K.1    Geisenhof, S.2    Kern, R.3    Eichenlaub, S.4    Reindl, C.5    Ellwart, J.W.6    Hiddemann, W.7    Spiekermann, K.8
  • 15
    • 0038156174 scopus 로고    scopus 로고
    • Sensitivity toward tyrosine kinase inhibitors varies between different activating mutations of the FLT3 receptor
    • Grundler R., Thiede C., Miething C., Steudel C., Peschel C., and Duyster J. Sensitivity toward tyrosine kinase inhibitors varies between different activating mutations of the FLT3 receptor. Blood 102 (2003) 646-651
    • (2003) Blood , vol.102 , pp. 646-651
    • Grundler, R.1    Thiede, C.2    Miething, C.3    Steudel, C.4    Peschel, C.5    Duyster, J.6
  • 17
    • 33746169020 scopus 로고    scopus 로고
    • FLT3 is fused to ETV6 in a myeloproliferative disorder with hypereosinophilia and a t(12;13)(p13;q12) translocation
    • Vu H.A., Xinh P.T., Masuda M., Motoji T., Toyoda A., Sakaki Y., Tokunaga K., and Sato Y. FLT3 is fused to ETV6 in a myeloproliferative disorder with hypereosinophilia and a t(12;13)(p13;q12) translocation. Leukemia 20 (2006) 1414-1421
    • (2006) Leukemia , vol.20 , pp. 1414-1421
    • Vu, H.A.1    Xinh, P.T.2    Masuda, M.3    Motoji, T.4    Toyoda, A.5    Sakaki, Y.6    Tokunaga, K.7    Sato, Y.8
  • 18
    • 0038820386 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription proteins in leukemias
    • Benekli M., Baer M.R., Baumann H., and Wetzler M. Signal transducer and activator of transcription proteins in leukemias. Blood 101 (2003) 2940-2954
    • (2003) Blood , vol.101 , pp. 2940-2954
    • Benekli, M.1    Baer, M.R.2    Baumann, H.3    Wetzler, M.4
  • 19
  • 20
    • 0037061747 scopus 로고    scopus 로고
    • Mechanism of constitutive activation of FLT3 with internal tandem duplication in the juxtamembrane domain
    • Kiyoi H., Ohno R., Ueda R., Saito H., and Naoe T. Mechanism of constitutive activation of FLT3 with internal tandem duplication in the juxtamembrane domain. Oncogene 21 (2002) 2555-2563
    • (2002) Oncogene , vol.21 , pp. 2555-2563
    • Kiyoi, H.1    Ohno, R.2    Ueda, R.3    Saito, H.4    Naoe, T.5
  • 21
    • 13544268345 scopus 로고    scopus 로고
    • Pim-1 is up-regulated by constitutively activated FLT3 and plays a role in FLT3-mediated cell survival
    • Kim K.T., Baird K., Ahn J.Y., Meltzer P., Lilly M., Levis M., and Small D. Pim-1 is up-regulated by constitutively activated FLT3 and plays a role in FLT3-mediated cell survival. Blood 105 (2005) 1759-1767
    • (2005) Blood , vol.105 , pp. 1759-1767
    • Kim, K.T.1    Baird, K.2    Ahn, J.Y.3    Meltzer, P.4    Lilly, M.5    Levis, M.6    Small, D.7
  • 22
    • 33746471790 scopus 로고    scopus 로고
    • Constitutively activated FLT3 phosphorylates BAD partially through Pim-1
    • Kim K.T., Levis M., and Small D. Constitutively activated FLT3 phosphorylates BAD partially through Pim-1. Br. J. Haematol. 134 (2009) 500-509
    • (2009) Br. J. Haematol. , vol.134 , pp. 500-509
    • Kim, K.T.1    Levis, M.2    Small, D.3
  • 24
    • 0035865960 scopus 로고    scopus 로고
    • Prolactin signaling to pim-1 expression: a role for phosphatidylinositol 3-kinase
    • Krumenacker J.S., Narang V.S., Buckley D.J., and Buckley A.R. Prolactin signaling to pim-1 expression: a role for phosphatidylinositol 3-kinase. J. Neuroimmunol. 113 (2001) 249-259
    • (2001) J. Neuroimmunol. , vol.113 , pp. 249-259
    • Krumenacker, J.S.1    Narang, V.S.2    Buckley, D.J.3    Buckley, A.R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.