-
1
-
-
65949112714
-
Aldehyde dehydrogenase 1 is a marker for normal and malignant human colonic stem cells (SC) and tracks SC overpopulation during colon tumorigenesis
-
COI: 1:CAS:528:DC%2BD1MXksV2hsb0%3D, PID: 19336570
-
Huang EH, Hynes MJ, Zhang T, Ginestier C, Dontu G, Appelman H, et al. Aldehyde dehydrogenase 1 is a marker for normal and malignant human colonic stem cells (SC) and tracks SC overpopulation during colon tumorigenesis. Cancer Res. 2009;69(8):3382–9. doi:10.1158/0008-5472.CAN-08-4418.
-
(2009)
Cancer Res
, vol.69
, Issue.8
, pp. 3382-3389
-
-
Huang, E.H.1
Hynes, M.J.2
Zhang, T.3
Ginestier, C.4
Dontu, G.5
Appelman, H.6
-
2
-
-
0030789242
-
Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
-
COI: 1:CAS:528:DyaK2sXkt1GrtLY%3D, PID: 9212098
-
Bonnet D, Dick JE. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat Med. 1997;3(7):730–7.
-
(1997)
Nat Med
, vol.3
, Issue.7
, pp. 730-737
-
-
Bonnet, D.1
Dick, J.E.2
-
3
-
-
49249091523
-
Identification and characterization of ovarian cancer-initiating cells from primary human tumors
-
COI: 1:CAS:528:DC%2BD1cXmsFKmuro%3D, PID: 18519691
-
Zhang S, Balch C, Chan MW, Lai HC, Matei D, Schilder JM, et al. Identification and characterization of ovarian cancer-initiating cells from primary human tumors. Cancer Res. 2008;68(11):4311–20. doi:10.1158/0008-5472.CAN-08-0364.
-
(2008)
Cancer Res
, vol.68
, Issue.11
, pp. 4311-4320
-
-
Zhang, S.1
Balch, C.2
Chan, M.W.3
Lai, H.C.4
Matei, D.5
Schilder, J.M.6
-
4
-
-
9244241576
-
Identification of human brain tumour initiating cells
-
COI: 1:CAS:528:DC%2BD2cXpvVCjtbY%3D, PID: 15549107
-
Singh SK, Hawkins C, Clarke ID, Squire JA, Bayani J, Hide T, et al. Identification of human brain tumour initiating cells. Nature. 2004;432(7015):396–401. doi:10.1038/nature03128.
-
(2004)
Nature
, vol.432
, Issue.7015
, pp. 396-401
-
-
Singh, S.K.1
Hawkins, C.2
Clarke, I.D.3
Squire, J.A.4
Bayani, J.5
Hide, T.6
-
5
-
-
33847052127
-
Identification of pancreatic cancer stem cells
-
COI: 1:CAS:528:DC%2BD2sXht1yns70%3D, PID: 17283135
-
Li C, Heidt DG, Dalerba P, Burant CF, Zhang L, Adsay V, et al. Identification of pancreatic cancer stem cells. Cancer Res. 2007;67(3):1030–7. doi:10.1158/0008-5472.CAN-06-2030.
-
(2007)
Cancer Res
, vol.67
, Issue.3
, pp. 1030-1037
-
-
Li, C.1
Heidt, D.G.2
Dalerba, P.3
Burant, C.F.4
Zhang, L.5
Adsay, V.6
-
6
-
-
35848955428
-
ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome
-
COI: 1:CAS:528:DC%2BD2sXhsVahtrvF, PID: 18371393
-
Ginestier C, Hur MH, Charafe-Jauffret E, Monville F, Dutcher J, Brown M, et al. ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome. Cell Stem Cell. 2007;1(5):555–67. doi:10.1016/j.stem.2007.08.014.
-
(2007)
Cell Stem Cell
, vol.1
, Issue.5
, pp. 555-567
-
-
Ginestier, C.1
Hur, M.H.2
Charafe-Jauffret, E.3
Monville, F.4
Dutcher, J.5
Brown, M.6
-
7
-
-
84860642507
-
The PSA(-/lo) prostate cancer cell population harbors self-renewing long-term tumor-propagating cells that resist castration
-
COI: 1:CAS:528:DC%2BC38Xms12ms70%3D, PID: 22560078
-
Qin J, Liu X, Laffin B, Chen X, Choy G, Jeter CR, et al. The PSA(-/lo) prostate cancer cell population harbors self-renewing long-term tumor-propagating cells that resist castration. Cell Stem Cell. 2012;10(5):556–69. doi:10.1016/j.stem.2012.03.009.
-
(2012)
Cell Stem Cell
, vol.10
, Issue.5
, pp. 556-569
-
-
Qin, J.1
Liu, X.2
Laffin, B.3
Chen, X.4
Choy, G.5
Jeter, C.R.6
-
8
-
-
40949160140
-
Identification of local and circulating cancer stem cells in human liver cancer
-
COI: 1:CAS:528:DC%2BD1cXktVOhs7w%3D, PID: 18275073
-
Yang ZF, Ngai P, Ho DW, Yu WC, Ng MN, Lau CK, et al. Identification of local and circulating cancer stem cells in human liver cancer. Hepatology. 2008;47(3):919–28. doi:10.1002/hep.22082.
-
(2008)
Hepatology
, vol.47
, Issue.3
, pp. 919-928
-
-
Yang, Z.F.1
Ngai, P.2
Ho, D.W.3
Yu, W.C.4
Ng, M.N.5
Lau, C.K.6
-
9
-
-
84871265890
-
Different effects of carbon ion beams and X-rays on clonogenic survival and DNA repair in human pancreatic cancer stem-like cells
-
COI: 1:CAS:528:DC%2BC38XhvVCrsr7O, PID: 23017870
-
Oonishi K, Cui X, Hirakawa H, Fujimori A, Kamijo T, Yamada S, et al. Different effects of carbon ion beams and X-rays on clonogenic survival and DNA repair in human pancreatic cancer stem-like cells. Radiother Oncol. 2012;105(2):258–65. doi:10.1016/j.radonc.2012.08.009.
-
(2012)
Radiother Oncol
, vol.105
, Issue.2
, pp. 258-265
-
-
Oonishi, K.1
Cui, X.2
Hirakawa, H.3
Fujimori, A.4
Kamijo, T.5
Yamada, S.6
-
10
-
-
84055222568
-
Identification of cancer stem cells in vincristine preconditioned SGC7901 gastric cancer cell line
-
COI: 1:CAS:528:DC%2BC3MXhs1Cgt73O, PID: 21913215
-
Xue Z, Yan H, Li J, Liang S, Cai X, Chen X, et al. Identification of cancer stem cells in vincristine preconditioned SGC7901 gastric cancer cell line. J Cell Biochem. 2012;113(1):302–12. doi:10.1002/jcb.23356.
-
(2012)
J Cell Biochem
, vol.113
, Issue.1
, pp. 302-312
-
-
Xue, Z.1
Yan, H.2
Li, J.3
Liang, S.4
Cai, X.5
Chen, X.6
-
11
-
-
84862737662
-
Identification of pancreatic cancer stem cells and selective toxicity of chemotherapeutic agents
-
COI: 1:CAS:528:DC%2BC38XptFansbc%3D, PID: 22510202
-
Adikrisna R, Tanaka S, Muramatsu S, Aihara A, Ban D, Ochiai T, et al. Identification of pancreatic cancer stem cells and selective toxicity of chemotherapeutic agents. Gastroenterology. 2012;143(1):234–45. doi:10.1053/j.gastro.2012.03.054.
-
(2012)
Gastroenterology
, vol.143
, Issue.1
, pp. 234-245
-
-
Adikrisna, R.1
Tanaka, S.2
Muramatsu, S.3
Aihara, A.4
Ban, D.5
Ochiai, T.6
-
12
-
-
75349105363
-
NOTCH pathway blockade depletes CD133-positive glioblastoma cells and inhibits growth of tumor neurospheres and xenografts
-
COI: 1:CAS:528:DC%2BC3cXis1WqsLY%3D
-
Fan X, Khaki L, Zhu TS, Soules ME, Talsma CE, Gul N, et al. NOTCH pathway blockade depletes CD133-positive glioblastoma cells and inhibits growth of tumor neurospheres and xenografts. Stem Cells (Dayton, Ohio). 2010;28(1):5–16. doi:10.1002/stem.254.
-
(2010)
Stem Cells (Dayton, Ohio)
, vol.28
, Issue.1
, pp. 5-16
-
-
Fan, X.1
Khaki, L.2
Zhu, T.S.3
Soules, M.E.4
Talsma, C.E.5
Gul, N.6
-
13
-
-
84877280627
-
The expression and significance of insulin-like growth factor-1 receptor and its pathway on breast cancer stemprogenitors
-
COI: 1:CAS:528:DC%2BC3sXhtVGqtb%2FO
-
Chang WW, Lin RJ, Yu J, Chang WY, Fu CH, Lai AC, et al. The expression and significance of insulin-like growth factor-1 receptor and its pathway on breast cancer stemprogenitors. Breast Cancer Res BCR. 2013;15(3):R39. doi:10.1186/bcr3423.
-
(2013)
Breast Cancer Res BCR
, vol.15
, Issue.3
, pp. 39
-
-
Chang, W.W.1
Lin, R.J.2
Yu, J.3
Chang, W.Y.4
Fu, C.H.5
Lai, A.C.6
-
14
-
-
84899524502
-
Reconstructing and reprogramming the tumor-propagating potential of glioblastoma stem-like cells
-
COI: 1:CAS:528:DC%2BC2cXmtVClurw%3D, PID: 24726434
-
Suva ML, Rheinbay E, Gillespie SM, Patel AP, Wakimoto H, Rabkin SD, et al. Reconstructing and reprogramming the tumor-propagating potential of glioblastoma stem-like cells. Cell. 2014;157(3):580–94. doi:10.1016/j.cell.2014.02.030.
-
(2014)
Cell
, vol.157
, Issue.3
, pp. 580-594
-
-
Suva, M.L.1
Rheinbay, E.2
Gillespie, S.M.3
Patel, A.P.4
Wakimoto, H.5
Rabkin, S.D.6
-
15
-
-
84881192827
-
Pharmacological inactivation of Skp2 SCF ubiquitin ligase restricts cancer stem cell traits and cancer progression
-
COI: 1:CAS:528:DC%2BC3sXht1WkurvI, PID: 23911321
-
Chan CH, Morrow JK, Li CF, Gao Y, Jin G, Moten A, et al. Pharmacological inactivation of Skp2 SCF ubiquitin ligase restricts cancer stem cell traits and cancer progression. Cell. 2013;154(3):556–68. doi:10.1016/j.cell.2013.06.048.
-
(2013)
Cell
, vol.154
, Issue.3
, pp. 556-568
-
-
Chan, C.H.1
Morrow, J.K.2
Li, C.F.3
Gao, Y.4
Jin, G.5
Moten, A.6
-
16
-
-
80052709582
-
Prognostic impact of CD133 mRNA expression in 48 glioblastoma patients treated with concomitant radiochemotherapy: a prospective patient cohort at a single institution
-
PID: 21479688
-
Metellus P, Nanni-Metellus I, Delfino C, Colin C, Tchogandjian A, Coulibaly B, et al. Prognostic impact of CD133 mRNA expression in 48 glioblastoma patients treated with concomitant radiochemotherapy: a prospective patient cohort at a single institution. Ann Surg Oncol. 2011;18(10):2937–45. doi:10.1245/s10434-011-1703-6.
-
(2011)
Ann Surg Oncol
, vol.18
, Issue.10
, pp. 2937-2945
-
-
Metellus, P.1
Nanni-Metellus, I.2
Delfino, C.3
Colin, C.4
Tchogandjian, A.5
Coulibaly, B.6
-
17
-
-
84883424297
-
Cancer stem cell gene profile as predictor of relapse in high risk stage II and stage III, radically resected colon cancer patients
-
COI: 1:CAS:528:DC%2BC3sXhsVCrsrfM, PID: 24023782
-
Giampieri R, Scartozzi M, Loretelli C, Piva F, Mandolesi A, Lezoche G, et al. Cancer stem cell gene profile as predictor of relapse in high risk stage II and stage III, radically resected colon cancer patients. PLoS One. 2013;8(9):e72843. doi:10.1371/journal.pone.0072843.
-
(2013)
PLoS One
, vol.8
, Issue.9
, pp. 72843
-
-
Giampieri, R.1
Scartozzi, M.2
Loretelli, C.3
Piva, F.4
Mandolesi, A.5
Lezoche, G.6
-
18
-
-
75449109041
-
Tumour CD133 mRNA expression and clinical outcome in surgically resected colorectal cancer patients
-
COI: 1:CAS:528:DC%2BC3cXhtlWrs7w%3D, PID: 20005089
-
Artells R, Moreno I, Diaz T, Martinez F, Gel B, Navarro A, et al. Tumour CD133 mRNA expression and clinical outcome in surgically resected colorectal cancer patients. Eur J Cancer. 2010;46(3):642–9. doi:10.1016/j.ejca.2009.11.003.
-
(2010)
Eur J Cancer
, vol.46
, Issue.3
, pp. 642-649
-
-
Artells, R.1
Moreno, I.2
Diaz, T.3
Martinez, F.4
Gel, B.5
Navarro, A.6
-
19
-
-
84875261402
-
Stage-specific embryonic antigen-4 is expressed in basaloid lung cancer and associated with poor prognosis
-
COI: 1:CAS:528:DC%2BC3sXlsVCitLo%3D, PID: 22743677
-
Gottschling S, Jensen K, Warth A, Herth FJ, Thomas M, Schnabel PA, et al. Stage-specific embryonic antigen-4 is expressed in basaloid lung cancer and associated with poor prognosis. Eur Respir J. 2013;41(3):656–63. doi:10.1183/09031936.00225711.
-
(2013)
Eur Respir J
, vol.41
, Issue.3
, pp. 656-663
-
-
Gottschling, S.1
Jensen, K.2
Warth, A.3
Herth, F.J.4
Thomas, M.5
Schnabel, P.A.6
-
20
-
-
84883743387
-
Telomerase reverse transcriptase promotes epithelial-mesenchymal transition and stem cell-like traits in cancer cells
-
COI: 1:CAS:528:DC%2BC38XhsVKks7bP, PID: 23045275
-
Liu Z, Li Q, Li K, Chen L, Li W, Hou M, et al. Telomerase reverse transcriptase promotes epithelial-mesenchymal transition and stem cell-like traits in cancer cells. Oncogene. 2013;32(36):4203–13. doi:10.1038/onc.2012.441.
-
(2013)
Oncogene
, vol.32
, Issue.36
, pp. 4203-4213
-
-
Liu, Z.1
Li, Q.2
Li, K.3
Chen, L.4
Li, W.5
Hou, M.6
-
21
-
-
84880267713
-
Impact of malignant stem cell burden on therapy outcome in newly diagnosed chronic myeloid leukemia patients
-
COI: 1:CAS:528:DC%2BC3sXhtFSiu7vE, PID: 23328954
-
Mustjoki S, Richter J, Barbany G, Ehrencrona H, Fioretos T, Gedde-Dahl T, et al. Impact of malignant stem cell burden on therapy outcome in newly diagnosed chronic myeloid leukemia patients. Leukemia. 2013;27(7):1520–6. doi:10.1038/leu.2013.19.
-
(2013)
Leukemia
, vol.27
, Issue.7
, pp. 1520-1526
-
-
Mustjoki, S.1
Richter, J.2
Barbany, G.3
Ehrencrona, H.4
Fioretos, T.5
Gedde-Dahl, T.6
-
22
-
-
66049085403
-
Glioma stem cell lines expanded in adherent culture have tumor-specific phenotypes and are suitable for chemical and genetic screens
-
COI: 1:CAS:528:DC%2BD1MXnt1Ggtbg%3D, PID: 19497285
-
Pollard SM, Yoshikawa K, Clarke ID, Danovi D, Stricker S, Russell R, et al. Glioma stem cell lines expanded in adherent culture have tumor-specific phenotypes and are suitable for chemical and genetic screens. Cell Stem Cell. 2009;4(6):568–80. doi:10.1016/j.stem.2009.03.014.
-
(2009)
Cell Stem Cell
, vol.4
, Issue.6
, pp. 568-580
-
-
Pollard, S.M.1
Yoshikawa, K.2
Clarke, I.D.3
Danovi, D.4
Stricker, S.5
Russell, R.6
-
23
-
-
84936746072
-
Cytogenetic landscape of paired neurospheres and traditional monolayer cultures in pediatric malignant brain tumors
-
Zhao X, Zhao YJ, Lin Q, Yu L, Liu Z, Lindsay H, et al. Cytogenetic landscape of paired neurospheres and traditional monolayer cultures in pediatric malignant brain tumors. Neuro-oncology. 2014;. doi:10.1093/neuonc/nou337.
-
(2014)
Neuro-oncology
-
-
Zhao, X.1
Zhao, Y.J.2
Lin, Q.3
Yu, L.4
Liu, Z.5
Lindsay, H.6
-
24
-
-
73149110562
-
Biological and molecular heterogeneity of breast cancers correlates with their cancer stem cell content
-
COI: 1:CAS:528:DC%2BC3cXkvVWiur0%3D, PID: 20074520
-
Pece S, Tosoni D, Confalonieri S, Mazzarol G, Vecchi M, Ronzoni S, et al. Biological and molecular heterogeneity of breast cancers correlates with their cancer stem cell content. Cell. 2010;140(1):62–73. doi:10.1016/j.cell.2009.12.007.
-
(2010)
Cell
, vol.140
, Issue.1
, pp. 62-73
-
-
Pece, S.1
Tosoni, D.2
Confalonieri, S.3
Mazzarol, G.4
Vecchi, M.5
Ronzoni, S.6
-
25
-
-
84913596527
-
In vivo imaging of Lgr5-positive cell populations using confocal laser endomicroscopy during early colon tumorigenesis
-
PID: 25216325
-
Choi JW, Kim JK, Choi M, Kim YR, Yun SH. In vivo imaging of Lgr5-positive cell populations using confocal laser endomicroscopy during early colon tumorigenesis. Endoscopy. 2014;46(12):1110–6. doi:10.1055/s-0034-1377631.
-
(2014)
Endoscopy
, vol.46
, Issue.12
, pp. 1110-1116
-
-
Choi, J.W.1
Kim, J.K.2
Choi, M.3
Kim, Y.R.4
Yun, S.H.5
-
26
-
-
33646376411
-
Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells
-
COI: 1:CAS:528:DC%2BD28XkvVykurY%3D, PID: 16598206
-
Yilmaz OH, Valdez R, Theisen BK, Guo W, Ferguson DO, Wu H, et al. Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells. Nature. 2006;441(7092):475–82. doi:10.1038/nature04703.
-
(2006)
Nature
, vol.441
, Issue.7092
, pp. 475-482
-
-
Yilmaz, O.H.1
Valdez, R.2
Theisen, B.K.3
Guo, W.4
Ferguson, D.O.5
Wu, H.6
-
27
-
-
84861995326
-
Identification of drugs including a dopamine receptor antagonist that selectively target cancer stem cells
-
COI: 1:CAS:528:DC%2BC38XnslSisb0%3D, PID: 22632761
-
Sachlos E, Risueno RM, Laronde S, Shapovalova Z, Lee JH, Russell J, et al. Identification of drugs including a dopamine receptor antagonist that selectively target cancer stem cells. Cell. 2012;149(6):1284–97. doi:10.1016/j.cell.2012.03.049.
-
(2012)
Cell
, vol.149
, Issue.6
, pp. 1284-1297
-
-
Sachlos, E.1
Risueno, R.M.2
Laronde, S.3
Shapovalova, Z.4
Lee, J.H.5
Russell, J.6
-
28
-
-
84868201589
-
ABCB5 expression and cancer stem cell hypothesis in oral squamous cell carcinoma
-
COI: 1:CAS:528:DC%2BC38XpvFOqtr0%3D, PID: 22784549
-
Grimm M, Krimmel M, Polligkeit J, Alexander D, Munz A, Kluba S, et al. ABCB5 expression and cancer stem cell hypothesis in oral squamous cell carcinoma. Eur J Cancer. 2012;48(17):3186–97. doi:10.1016/j.ejca.2012.05.027.
-
(2012)
Eur J Cancer
, vol.48
, Issue.17
, pp. 3186-3197
-
-
Grimm, M.1
Krimmel, M.2
Polligkeit, J.3
Alexander, D.4
Munz, A.5
Kluba, S.6
-
29
-
-
20144364789
-
ABCB5-mediated doxorubicin transport and chemoresistance in human malignant melanoma
-
COI: 1:CAS:528:DC%2BD2MXktlSmt7Y%3D, PID: 15899824
-
Frank NY, Margaryan A, Huang Y, Schatton T, Waaga-Gasser AM, Gasser M, et al. ABCB5-mediated doxorubicin transport and chemoresistance in human malignant melanoma. Cancer Res. 2005;65(10):4320–33. doi:10.1158/0008-5472.CAN-04-3327.
-
(2005)
Cancer Res
, vol.65
, Issue.10
, pp. 4320-4333
-
-
Frank, N.Y.1
Margaryan, A.2
Huang, Y.3
Schatton, T.4
Waaga-Gasser, A.M.5
Gasser, M.6
-
30
-
-
84872294586
-
Metformin selectively affects human glioblastoma tumor-initiating cell viability: a role for metformin-induced inhibition of Akt
-
COI: 1:CAS:528:DC%2BC3sXisVKrsbo%3D
-
Wurth R, Pattarozzi A, Gatti M, Bajetto A, Corsaro A, Parodi A, et al. Metformin selectively affects human glioblastoma tumor-initiating cell viability: a role for metformin-induced inhibition of Akt. Cell Cycle (Georgetown, Tex). 2013;12(1):145–56. doi:10.4161/cc.23050.
-
(2013)
Cell Cycle (Georgetown, Tex)
, vol.12
, Issue.1
, pp. 145-156
-
-
Wurth, R.1
Pattarozzi, A.2
Gatti, M.3
Bajetto, A.4
Corsaro, A.5
Parodi, A.6
-
31
-
-
39649085170
-
Rapid and selective death of leukemia stem and progenitor cells induced by the compound 4-benzyl, 2-methyl, 1,2,4-thiadiazolidine, 3,5 dione (TDZD-8)
-
COI: 1:CAS:528:DC%2BD1cXot1Wn, PID: 17785584
-
Guzman ML, Li X, Corbett CA, Rossi RM, Bushnell T, Liesveld JL, et al. Rapid and selective death of leukemia stem and progenitor cells induced by the compound 4-benzyl, 2-methyl, 1,2,4-thiadiazolidine, 3,5 dione (TDZD-8). Blood. 2007;110(13):4436–44. doi:10.1182/blood-2007-05-088815.
-
(2007)
Blood
, vol.110
, Issue.13
, pp. 4436-4444
-
-
Guzman, M.L.1
Li, X.2
Corbett, C.A.3
Rossi, R.M.4
Bushnell, T.5
Liesveld, J.L.6
-
32
-
-
33845317573
-
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
-
COI: 1:CAS:528:DC%2BD28Xht1OntbzP, PID: 17051156
-
Bao S, Wu Q, McLendon RE, Hao Y, Shi Q, Hjelmeland AB, et al. Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature. 2006;444(7120):756–60. doi:10.1038/nature05236.
-
(2006)
Nature
, vol.444
, Issue.7120
, pp. 756-760
-
-
Bao, S.1
Wu, Q.2
McLendon, R.E.3
Hao, Y.4
Shi, Q.5
Hjelmeland, A.B.6
-
33
-
-
77950231070
-
CD44 attenuates activation of the hippo signaling pathway and is a prime therapeutic target for glioblastoma
-
COI: 1:CAS:528:DC%2BC3cXjtFygtb0%3D, PID: 20197461
-
Xu Y, Stamenkovic I, Yu Q. CD44 attenuates activation of the hippo signaling pathway and is a prime therapeutic target for glioblastoma. Cancer Res. 2010;70(6):2455–64. doi:10.1158/0008-5472.CAN-09-2505.
-
(2010)
Cancer Res
, vol.70
, Issue.6
, pp. 2455-2464
-
-
Xu, Y.1
Stamenkovic, I.2
Yu, Q.3
-
34
-
-
33747513134
-
Notch signalling regulates stem cell numbers in vitro and in vivo
-
COI: 1:CAS:528:DC%2BD28XotFKmsLs%3D, PID: 16799564
-
Androutsellis-Theotokis A, Leker RR, Soldner F, Hoeppner DJ, Ravin R, Poser SW, et al. Notch signalling regulates stem cell numbers in vitro and in vivo. Nature. 2006;442(7104):823–6. doi:10.1038/nature04940.
-
(2006)
Nature
, vol.442
, Issue.7104
, pp. 823-826
-
-
Androutsellis-Theotokis, A.1
Leker, R.R.2
Soldner, F.3
Hoeppner, D.J.4
Ravin, R.5
Poser, S.W.6
-
35
-
-
80053568372
-
Notch post-translationally regulates beta-catenin protein in stem and progenitor cells
-
COI: 1:CAS:528:DC%2BC3MXhtFylsLvO, PID: 21841793
-
Kwon C, Cheng P, King IN, Andersen P, Shenje L, Nigam V, et al. Notch post-translationally regulates beta-catenin protein in stem and progenitor cells. Nat Cell Biol. 2011;13(10):1244–51. doi:10.1038/ncb2313.
-
(2011)
Nat Cell Biol
, vol.13
, Issue.10
, pp. 1244-1251
-
-
Kwon, C.1
Cheng, P.2
King, I.N.3
Andersen, P.4
Shenje, L.5
Nigam, V.6
-
36
-
-
0032126751
-
Notch receptor activation inhibits oligodendrocyte differentiation
-
PID: 9697852
-
Wang S, Sdrulla AD, diSibio G, Bush G, Nofziger D, Hicks C, et al. Notch receptor activation inhibits oligodendrocyte differentiation. Neuron. 1998;21(1):63–75.
-
(1998)
Neuron
, vol.21
, Issue.1
, pp. 63-75
-
-
Wang, S.1
Sdrulla, A.D.2
diSibio, G.3
Bush, G.4
Nofziger, D.5
Hicks, C.6
-
37
-
-
0037370310
-
Notch1 functions as a tumor suppressor in mouse skin
-
COI: 1:CAS:528:DC%2BD3sXhsV2kurs%3D, PID: 12590261
-
Nicolas M, Wolfer A, Raj K, Kummer JA, Mill P, van Noort M, et al. Notch1 functions as a tumor suppressor in mouse skin. Nat Genet. 2003;33(3):416–21. doi:10.1038/ng1099.
-
(2003)
Nat Genet
, vol.33
, Issue.3
, pp. 416-421
-
-
Nicolas, M.1
Wolfer, A.2
Raj, K.3
Kummer, J.A.4
Mill, P.5
van Noort, M.6
-
38
-
-
0037313331
-
t(11;19)(q21;p13) translocation in mucoepidermoid carcinoma creates a novel fusion product that disrupts a Notch signaling pathway
-
COI: 1:CAS:528:DC%2BD3sXnsFSkug%3D%3D, PID: 12539049
-
Tonon G, Modi S, Wu L, Kubo A, Coxon AB, Komiya T, et al. t(11;19)(q21;p13) translocation in mucoepidermoid carcinoma creates a novel fusion product that disrupts a Notch signaling pathway. Nat Genet. 2003;33(2):208–13. doi:10.1038/ng1083.
-
(2003)
Nat Genet
, vol.33
, Issue.2
, pp. 208-213
-
-
Tonon, G.1
Modi, S.2
Wu, L.3
Kubo, A.4
Coxon, A.B.5
Komiya, T.6
-
39
-
-
77953700950
-
Targeting notch to target cancer stem cells
-
COI: 1:CAS:528:DC%2BC3cXntlKru70%3D, PID: 20530696
-
Pannuti A, Foreman K, Rizzo P, Osipo C, Golde T, Osborne B, et al. Targeting notch to target cancer stem cells. Clin Cancer Res. 2010;16(12):3141–52. doi:10.1158/1078-0432.CCR-09-2823.
-
(2010)
Clin Cancer Res
, vol.16
, Issue.12
, pp. 3141-3152
-
-
Pannuti, A.1
Foreman, K.2
Rizzo, P.3
Osipo, C.4
Golde, T.5
Osborne, B.6
-
40
-
-
77956623598
-
Inhibition of notch signaling in glioblastoma targets cancer stem cells via an endothelial cell intermediate
-
COI: 1:CAS:528:DC%2BC3cXptlWlt70%3D
-
Hovinga KE, Shimizu F, Wang R, Panagiotakos G, Van Der Heijden M, Moayedpardazi H, et al. Inhibition of notch signaling in glioblastoma targets cancer stem cells via an endothelial cell intermediate. Stem Cells (Dayton, Ohio). 2010;28(6):1019–29. doi:10.1002/stem.429.
-
(2010)
Stem Cells (Dayton, Ohio)
, vol.28
, Issue.6
, pp. 1019-1029
-
-
Hovinga, K.E.1
Shimizu, F.2
Wang, R.3
Panagiotakos, G.4
Van Der Heijden, M.5
Moayedpardazi, H.6
-
41
-
-
75349108271
-
Notch promotes radioresistance of glioma stem cells
-
COI: 1:CAS:528:DC%2BC3cXis1Wqsb8%3D
-
Wang J, Wakeman TP, Lathia JD, Hjelmeland AB, Wang XF, White RR, et al. Notch promotes radioresistance of glioma stem cells. Stem Cells (Dayton, Ohio). 2010;28(1):17–28. doi:10.1002/stem.261.
-
(2010)
Stem Cells (Dayton, Ohio)
, vol.28
, Issue.1
, pp. 17-28
-
-
Wang, J.1
Wakeman, T.P.2
Lathia, J.D.3
Hjelmeland, A.B.4
Wang, X.F.5
White, R.R.6
-
42
-
-
0035907041
-
Beta-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin
-
COI: 1:CAS:528:DC%2BD3MXksFektLg%3D, PID: 11371349
-
Huelsken J, Vogel R, Erdmann B, Cotsarelis G, Birchmeier W. Beta-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin. Cell. 2001;105(4):533–45.
-
(2001)
Cell
, vol.105
, Issue.4
, pp. 533-545
-
-
Huelsken, J.1
Vogel, R.2
Erdmann, B.3
Cotsarelis, G.4
Birchmeier, W.5
-
43
-
-
67650230896
-
Wnt/beta-catenin signaling: components, mechanisms, and diseases
-
COI: 1:CAS:528:DC%2BD1MXpsV2msb8%3D, PID: 19619488
-
MacDonald BT, Tamai K, He X. Wnt/beta-catenin signaling: components, mechanisms, and diseases. Dev Cell. 2009;17(1):9–26. doi:10.1016/j.devcel.2009.06.016.
-
(2009)
Dev Cell
, vol.17
, Issue.1
, pp. 9-26
-
-
MacDonald, B.T.1
Tamai, K.2
He, X.3
-
44
-
-
0037737726
-
Wnt proteins are lipid-modified and can act as stem cell growth factors
-
COI: 1:CAS:528:DC%2BD3sXjvFalt7c%3D, PID: 12717451
-
Willert K, Brown JD, Danenberg E, Duncan AW, Weissman IL, Reya T, et al. Wnt proteins are lipid-modified and can act as stem cell growth factors. Nature. 2003;423(6938):448–52. doi:10.1038/nature01611.
-
(2003)
Nature
, vol.423
, Issue.6938
, pp. 448-452
-
-
Willert, K.1
Brown, J.D.2
Danenberg, E.3
Duncan, A.W.4
Weissman, I.L.5
Reya, T.6
-
45
-
-
58949102946
-
A two-step mechanism for stem cell activation during hair regeneration
-
COI: 1:CAS:528:DC%2BD1MXitFSjtLY%3D, PID: 19200804
-
Greco V, Chen T, Rendl M, Schober M, Pasolli HA, Stokes N, et al. A two-step mechanism for stem cell activation during hair regeneration. Cell Stem Cell. 2009;4(2):155–69. doi:10.1016/j.stem.2008.12.009.
-
(2009)
Cell Stem Cell
, vol.4
, Issue.2
, pp. 155-169
-
-
Greco, V.1
Chen, T.2
Rendl, M.3
Schober, M.4
Pasolli, H.A.5
Stokes, N.6
-
46
-
-
80053063127
-
Maintaining embryonic stem cell pluripotency with Wnt signaling
-
COI: 1:CAS:528:DC%2BC3MXhsV2nt7nK, PID: 21903672
-
Sokol SY. Maintaining embryonic stem cell pluripotency with Wnt signaling. Development. 2011;138(20):4341–50. doi:10.1242/dev.066209.
-
(2011)
Development
, vol.138
, Issue.20
, pp. 4341-4350
-
-
Sokol, S.Y.1
-
47
-
-
33846193290
-
The many ways of Wnt in cancer
-
COI: 1:CAS:528:DC%2BD2sXnslOnsw%3D%3D, PID: 17208432
-
Polakis P. The many ways of Wnt in cancer. Curr Opin Genet Dev. 2007;17(1):45–51. doi:10.1016/j.gde.2006.12.007.
-
(2007)
Curr Opin Genet Dev
, vol.17
, Issue.1
, pp. 45-51
-
-
Polakis, P.1
-
48
-
-
70350502857
-
PARsing the phrase “all in for Axin”-Wnt pathway targets in cancer
-
COI: 1:CAS:528:DC%2BD1MXhsFKltbzL, PID: 19878868
-
Fearon ER. PARsing the phrase “all in for Axin”-Wnt pathway targets in cancer. Cancer Cell. 2009;16(5):366–8. doi:10.1016/j.ccr.2009.10.007.
-
(2009)
Cancer Cell
, vol.16
, Issue.5
, pp. 366-368
-
-
Fearon, E.R.1
-
49
-
-
33751530490
-
Mining the Wnt pathway for cancer therapeutics
-
COI: 1:CAS:528:DC%2BD28Xht1Kju7vK, PID: 17139285
-
Barker N, Clevers H. Mining the Wnt pathway for cancer therapeutics. Nat Rev Drug Discov. 2006;5(12):997–1014. doi:10.1038/nrd2154.
-
(2006)
Nat Rev Drug Discov
, vol.5
, Issue.12
, pp. 997-1014
-
-
Barker, N.1
Clevers, H.2
-
50
-
-
33847740988
-
Wnt/beta-catenin signaling in cancer stemness and malignant behavior
-
COI: 1:CAS:528:DC%2BD2sXjt1Slu7s%3D, PID: 17306971
-
Fodde R, Brabletz T. Wnt/beta-catenin signaling in cancer stemness and malignant behavior. Curr Opin Cell Biol. 2007;19(2):150–8. doi:10.1016/j.ceb.2007.02.007.
-
(2007)
Curr Opin Cell Biol
, vol.19
, Issue.2
, pp. 150-158
-
-
Fodde, R.1
Brabletz, T.2
-
51
-
-
84888298769
-
The Wnt/beta-catenin pathway in ovarian cancer: a review
-
COI: 1:CAS:528:DC%2BC3sXhs1Ortb7F, PID: 24125749
-
Arend RC, Londono-Joshi AI, Straughn JM Jr, Buchsbaum DJ. The Wnt/beta-catenin pathway in ovarian cancer: a review. Gynecol Oncol. 2013;131(3):772–9. doi:10.1016/j.ygyno.2013.09.034.
-
(2013)
Gynecol Oncol
, vol.131
, Issue.3
, pp. 772-779
-
-
Arend, R.C.1
Londono-Joshi, A.I.2
Straughn, J.M.3
Buchsbaum, D.J.4
-
52
-
-
84957591389
-
Roles of Wnt/beta-catenin signaling in the gastric cancer stem cells proliferation and salinomycin treatment
-
COI: 1:CAS:528:DC%2BC2cXhsl2gsL0%3D, PID: 24481453
-
Mao J, Fan S, Ma W, Fan P, Wang B, Zhang J, et al. Roles of Wnt/beta-catenin signaling in the gastric cancer stem cells proliferation and salinomycin treatment. Cell Death Dis. 2014;5:e1039. doi:10.1038/cddis.2013.515.
-
(2014)
Cell Death Dis
, vol.5
, pp. 1039
-
-
Mao, J.1
Fan, S.2
Ma, W.3
Fan, P.4
Wang, B.5
Zhang, J.6
-
53
-
-
78449255989
-
miR-200a regulates epithelial-mesenchymal to stem-like transition via ZEB2 and beta-catenin signaling
-
COI: 1:CAS:528:DC%2BC3cXhsVWgsrnI, PID: 20826811
-
Xia H, Cheung WK, Sze J, Lu G, Jiang S, Yao H, et al. miR-200a regulates epithelial-mesenchymal to stem-like transition via ZEB2 and beta-catenin signaling. J Biol Chem. 2010;285(47):36995–7004. doi:10.1074/jbc.M110.133744.
-
(2010)
J Biol Chem
, vol.285
, Issue.47
, pp. 36995-37004
-
-
Xia, H.1
Cheung, W.K.2
Sze, J.3
Lu, G.4
Jiang, S.5
Yao, H.6
-
54
-
-
84862638243
-
Antagonism of miR-21 reverses epithelial-mesenchymal transition and cancer stem cell phenotype through AKT/ERK1/2 inactivation by targeting PTEN
-
COI: 1:CAS:528:DC%2BC38XpsFyitbw%3D, PID: 22761812
-
Han M, Liu M, Wang Y, Chen X, Xu J, Sun Y, et al. Antagonism of miR-21 reverses epithelial-mesenchymal transition and cancer stem cell phenotype through AKT/ERK1/2 inactivation by targeting PTEN. PLoS One. 2012;7(6):e39520. doi:10.1371/journal.pone.0039520.
-
(2012)
PLoS One
, vol.7
, Issue.6
, pp. 39520
-
-
Han, M.1
Liu, M.2
Wang, Y.3
Chen, X.4
Xu, J.5
Sun, Y.6
-
55
-
-
79351468712
-
Activation of beta-catenin and Akt pathways by Twist are critical for the maintenance of EMT associated cancer stem cell-like characters
-
PID: 21284870
-
Li J, Zhou BP. Activation of beta-catenin and Akt pathways by Twist are critical for the maintenance of EMT associated cancer stem cell-like characters. BMC Cancer. 2011;11:49. doi:10.1186/1471-2407-11-49.
-
(2011)
BMC Cancer
, vol.11
, pp. 49
-
-
Li, J.1
Zhou, B.P.2
-
56
-
-
0028170210
-
A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002)
-
COI: 1:CAS:528:DyaK2cXjtFGit78%3D, PID: 8106507
-
Vlahos CJ, Matter WF, Hui KY, Brown RF. A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002). J Biol Chem. 1994;269(7):5241–8.
-
(1994)
J Biol Chem
, vol.269
, Issue.7
, pp. 5241-5248
-
-
Vlahos, C.J.1
Matter, W.F.2
Hui, K.Y.3
Brown, R.F.4
-
57
-
-
34948908663
-
Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia
-
COI: 1:CAS:528:DC%2BD2sXhtFagsb3F, PID: 17873882
-
Palomero T, Sulis ML, Cortina M, Real PJ, Barnes K, Ciofani M, et al. Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia. Nat Med. 2007;13(10):1203–10. doi:10.1038/nm1636.
-
(2007)
Nat Med
, vol.13
, Issue.10
, pp. 1203-1210
-
-
Palomero, T.1
Sulis, M.L.2
Cortina, M.3
Real, P.J.4
Barnes, K.5
Ciofani, M.6
-
58
-
-
62549099008
-
The VEGF pathway and the AKT/mTOR/p70S6K1 signalling pathway in human epithelial ovarian cancer
-
COI: 1:CAS:528:DC%2BD1MXjt1Gjsbk%3D, PID: 19240722
-
Trinh XB, Tjalma WA, Vermeulen PB, Van den Eynden G, Van der Auwera I, Van Laere SJ, et al. The VEGF pathway and the AKT/mTOR/p70S6K1 signalling pathway in human epithelial ovarian cancer. Br J Cancer. 2009;100(6):971–8. doi:10.1038/sj.bjc.6604921.
-
(2009)
Br J Cancer
, vol.100
, Issue.6
, pp. 971-978
-
-
Trinh, X.B.1
Tjalma, W.A.2
Vermeulen, P.B.3
Van den Eynden, G.4
Van der Auwera, I.5
Van Laere, S.J.6
-
59
-
-
57749119410
-
CXCR6 induces prostate cancer progression by the AKT mammalian target of rapamycin signaling pathway
-
COI: 1:CAS:528:DC%2BD1cXhsV2itLzM, PID: 19074906
-
Wang J, Lu Y, Koch AE, Zhang J, Taichman RS. CXCR6 induces prostate cancer progression by the AKT mammalian target of rapamycin signaling pathway. Cancer Res. 2008;68(24):10367–76. doi:10.1158/0008-5472.can-08-2780.
-
(2008)
Cancer Res
, vol.68
, Issue.24
, pp. 10367-10376
-
-
Wang, J.1
Lu, Y.2
Koch, A.E.3
Zhang, J.4
Taichman, R.S.5
-
60
-
-
84878776929
-
Akt-signal integration is involved in the differentiation of embryonal carcinoma cells
-
COI: 1:CAS:528:DC%2BC3sXpvFKhs70%3D, PID: 23762260
-
Chen B, Xue Z, Yang G, Shi B, Yang B, Yan Y, et al. Akt-signal integration is involved in the differentiation of embryonal carcinoma cells. PLoS One. 2013;8(6):e64877. doi:10.1371/journal.pone.0064877.
-
(2013)
PLoS One
, vol.8
, Issue.6
, pp. 64877
-
-
Chen, B.1
Xue, Z.2
Yang, G.3
Shi, B.4
Yang, B.5
Yan, Y.6
-
61
-
-
84885392997
-
Involvement of miRNAs in the differentiation of human glioblastoma multiforme stem-like cells
-
COI: 1:CAS:528:DC%2BC3sXhs1KiurvL, PID: 24155920
-
Aldaz B, Sagardoy A, Nogueira L, Guruceaga E, Grande L, Huse JT, et al. Involvement of miRNAs in the differentiation of human glioblastoma multiforme stem-like cells. PLoS One. 2013;8(10):e77098. doi:10.1371/journal.pone.0077098.
-
(2013)
PLoS One
, vol.8
, Issue.10
, pp. 77098
-
-
Aldaz, B.1
Sagardoy, A.2
Nogueira, L.3
Guruceaga, E.4
Grande, L.5
Huse, J.T.6
-
62
-
-
84875992975
-
Wnt activation promotes neuronal differentiation of glioblastoma
-
COI: 1:CAS:528:DC%2BC3sXhtVyrsrrP, PID: 23429286
-
Rampazzo E, Persano L, Pistollato F, Moro E, Frasson C, Porazzi P, et al. Wnt activation promotes neuronal differentiation of glioblastoma. Cell Death Dis. 2013;4:e500. doi:10.1038/cddis.2013.32.
-
(2013)
Cell Death Dis
, vol.4
, pp. 500
-
-
Rampazzo, E.1
Persano, L.2
Pistollato, F.3
Moro, E.4
Frasson, C.5
Porazzi, P.6
-
63
-
-
84862317152
-
CD90 is identified as a marker for cancer stem cells in primary high-grade gliomas using tissue microarrays
-
He J, Liu Y, Zhu T, Zhu J, Dimeco F, Vescovi AL, et al. CD90 is identified as a marker for cancer stem cells in primary high-grade gliomas using tissue microarrays. Mol Cell Proteomics MCP. 2012;11(6):M111 010744. doi:10.1074/mcp.M111.010744.
-
(2012)
Mol Cell Proteomics MCP
, vol.11
, Issue.6
, pp. 111 010744
-
-
He, J.1
Liu, Y.2
Zhu, T.3
Zhu, J.4
Dimeco, F.5
Vescovi, A.L.6
-
64
-
-
68749099671
-
Identification of selective inhibitors of cancer stem cells by high-throughput screening
-
COI: 1:CAS:528:DC%2BD1MXhsVCjs73E, PID: 19682730
-
Gupta PB, Onder TT, Jiang G, Tao K, Kuperwasser C, Weinberg RA, et al. Identification of selective inhibitors of cancer stem cells by high-throughput screening. Cell. 2009;138(4):645–59. doi:10.1016/j.cell.2009.06.034.
-
(2009)
Cell
, vol.138
, Issue.4
, pp. 645-659
-
-
Gupta, P.B.1
Onder, T.T.2
Jiang, G.3
Tao, K.4
Kuperwasser, C.5
Weinberg, R.A.6
-
65
-
-
77952329017
-
Differentiation therapy exerts antitumor effects on stem-like glioma cells
-
COI: 1:CAS:528:DC%2BC3cXlvF2iu7o%3D, PID: 20442299
-
Campos B, Wan F, Farhadi M, Ernst A, Zeppernick F, Tagscherer KE, et al. Differentiation therapy exerts antitumor effects on stem-like glioma cells. Clin Cancer Res. 2010;16(10):2715–28. doi:10.1158/1078-0432.CCR-09-1800.
-
(2010)
Clin Cancer Res
, vol.16
, Issue.10
, pp. 2715-2728
-
-
Campos, B.1
Wan, F.2
Farhadi, M.3
Ernst, A.4
Zeppernick, F.5
Tagscherer, K.E.6
-
66
-
-
84855859957
-
Differentiation therapy: targeting human renal cancer stem cells with interleukin 15
-
COI: 1:CAS:528:DC%2BC3MXhs12ht7fK, PID: 22043039
-
Azzi S, Bruno S, Giron-Michel J, Clay D, Devocelle A, Croce M, et al. Differentiation therapy: targeting human renal cancer stem cells with interleukin 15. J Natl Cancer Inst. 2011;103(24):1884–98. doi:10.1093/jnci/djr451.
-
(2011)
J Natl Cancer Inst
, vol.103
, Issue.24
, pp. 1884-1898
-
-
Azzi, S.1
Bruno, S.2
Giron-Michel, J.3
Clay, D.4
Devocelle, A.5
Croce, M.6
-
67
-
-
84859512866
-
Non-coding RNAs: key regulators of mammalian transcription
-
COI: 1:CAS:528:DC%2BC38XlsFGgsrc%3D, PID: 22300815
-
Kugel JF, Goodrich JA. Non-coding RNAs: key regulators of mammalian transcription. Trends Biochem Sci. 2012;37(4):144–51. doi:10.1016/j.tibs.2011.12.003.
-
(2012)
Trends Biochem Sci
, vol.37
, Issue.4
, pp. 144-151
-
-
Kugel, J.F.1
Goodrich, J.A.2
-
68
-
-
78651390167
-
Long intergenic noncoding RNAs: new links in cancer progression
-
COI: 1:CAS:528:DC%2BC3MXovF2l, PID: 21199792
-
Tsai MC, Spitale RC, Chang HY. Long intergenic noncoding RNAs: new links in cancer progression. Cancer Res. 2011;71(1):3–7. doi:10.1158/0008-5472.CAN-10-2483.
-
(2011)
Cancer Res
, vol.71
, Issue.1
, pp. 3-7
-
-
Tsai, M.C.1
Spitale, R.C.2
Chang, H.Y.3
-
69
-
-
36849078711
-
let-7 regulates self renewal and tumorigenicity of breast cancer cells
-
COI: 1:CAS:528:DC%2BD1cXksFGgtQ%3D%3D, PID: 18083101
-
Yu F, Yao H, Zhu P, Zhang X, Pan Q, Gong C, et al. let-7 regulates self renewal and tumorigenicity of breast cancer cells. Cell. 2007;131(6):1109–23. doi:10.1016/j.cell.2007.10.054.
-
(2007)
Cell
, vol.131
, Issue.6
, pp. 1109-1123
-
-
Yu, F.1
Yao, H.2
Zhu, P.3
Zhang, X.4
Pan, Q.5
Gong, C.6
-
70
-
-
68049114782
-
Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells
-
COI: 1:CAS:528:DC%2BD1MXhsVChs7bP, PID: 19665978
-
Shimono Y, Zabala M, Cho RW, Lobo N, Dalerba P, Qian D, et al. Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells. Cell. 2009;138(3):592–603. doi:10.1016/j.cell.2009.07.011.
-
(2009)
Cell
, vol.138
, Issue.3
, pp. 592-603
-
-
Shimono, Y.1
Zabala, M.2
Cho, R.W.3
Lobo, N.4
Dalerba, P.5
Qian, D.6
-
71
-
-
84880570961
-
MicroRNA-antagonism regulates breast cancer stemness and metastasis via TET-family-dependent chromatin remodeling
-
COI: 1:CAS:528:DC%2BC3sXhtVGrtb3F, PID: 23830207
-
Song SJ, Poliseno L, Song MS, Ala U, Webster K, Ng C, et al. MicroRNA-antagonism regulates breast cancer stemness and metastasis via TET-family-dependent chromatin remodeling. Cell. 2013;154(2):311–24. doi:10.1016/j.cell.2013.06.026.
-
(2013)
Cell
, vol.154
, Issue.2
, pp. 311-324
-
-
Song, S.J.1
Poliseno, L.2
Song, M.S.3
Ala, U.4
Webster, K.5
Ng, C.6
-
72
-
-
84880571480
-
The oncogenic microRNA miR-22 targets the TET2 tumor suppressor to promote hematopoietic stem cell self-renewal and transformation
-
COI: 1:CAS:528:DC%2BC3sXhtVGrsrfO, PID: 23827711
-
Song SJ, Ito K, Ala U, Kats L, Webster K, Sun SM, et al. The oncogenic microRNA miR-22 targets the TET2 tumor suppressor to promote hematopoietic stem cell self-renewal and transformation. Cell Stem Cell. 2013;13(1):87–101. doi:10.1016/j.stem.2013.06.003.
-
(2013)
Cell Stem Cell
, vol.13
, Issue.1
, pp. 87-101
-
-
Song, S.J.1
Ito, K.2
Ala, U.3
Kats, L.4
Webster, K.5
Sun, S.M.6
-
73
-
-
84895463099
-
MicroRNA-146a directs the symmetric division of Snail-dominant colorectal cancer stem cells
-
COI: 1:CAS:528:DC%2BC2cXivFamsbY%3D, PID: 24561623
-
Hwang WL, Jiang JK, Yang SH, Huang TS, Lan HY, Teng HW, et al. MicroRNA-146a directs the symmetric division of Snail-dominant colorectal cancer stem cells. Nat Cell Biol. 2014;16(3):268–80. doi:10.1038/ncb2910.
-
(2014)
Nat Cell Biol
, vol.16
, Issue.3
, pp. 268-280
-
-
Hwang, W.L.1
Jiang, J.K.2
Yang, S.H.3
Huang, T.S.4
Lan, H.Y.5
Teng, H.W.6
-
74
-
-
84884354300
-
Myeloid-derived suppressor cells enhance stemness of cancer cells by inducing microRNA101 and suppressing the corepressor CtBP2
-
COI: 1:CAS:528:DC%2BC3sXhtl2ksbzO, PID: 24012420
-
Cui TX, Kryczek I, Zhao L, Zhao E, Kuick R, Roh MH, et al. Myeloid-derived suppressor cells enhance stemness of cancer cells by inducing microRNA101 and suppressing the corepressor CtBP2. Immunity. 2013;39(3):611–21. doi:10.1016/j.immuni.2013.08.025.
-
(2013)
Immunity
, vol.39
, Issue.3
, pp. 611-621
-
-
Cui, T.X.1
Kryczek, I.2
Zhao, L.3
Zhao, E.4
Kuick, R.5
Roh, M.H.6
-
75
-
-
79952283482
-
p53 regulates epithelial-mesenchymal transition and stem cell properties through modulating miRNAs
-
COI: 1:CAS:528:DC%2BC3MXisFKntrg%3D, PID: 21336307
-
Chang CJ, Chao CH, Xia W, Yang JY, Xiong Y, Li CW, et al. p53 regulates epithelial-mesenchymal transition and stem cell properties through modulating miRNAs. Nat Cell Biol. 2011;13(3):317–23. doi:10.1038/ncb2173.
-
(2011)
Nat Cell Biol
, vol.13
, Issue.3
, pp. 317-323
-
-
Chang, C.J.1
Chao, C.H.2
Xia, W.3
Yang, J.Y.4
Xiong, Y.5
Li, C.W.6
-
76
-
-
77955323879
-
A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response
-
COI: 1:CAS:528:DC%2BC3cXpvFKrtrg%3D, PID: 20673990
-
Huarte M, Guttman M, Feldser D, Garber M, Koziol MJ, Kenzelmann-Broz D, et al. A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response. Cell. 2010;142(3):409–19. doi:10.1016/j.cell.2010.06.040.
-
(2010)
Cell
, vol.142
, Issue.3
, pp. 409-419
-
-
Huarte, M.1
Guttman, M.2
Feldser, D.3
Garber, M.4
Koziol, M.J.5
Kenzelmann-Broz, D.6
-
77
-
-
78649467088
-
Large intergenic non-coding RNA-RoR modulates reprogramming of human induced pluripotent stem cells
-
COI: 1:CAS:528:DC%2BC3cXhtl2jsbzE, PID: 21057500
-
Loewer S, Cabili MN, Guttman M, Loh YH, Thomas K, Park IH, et al. Large intergenic non-coding RNA-RoR modulates reprogramming of human induced pluripotent stem cells. Nat Genet. 2010;42(12):1113–7. doi:10.1038/ng.710.
-
(2010)
Nat Genet
, vol.42
, Issue.12
, pp. 1113-1117
-
-
Loewer, S.1
Cabili, M.N.2
Guttman, M.3
Loh, Y.H.4
Thomas, K.5
Park, I.H.6
-
78
-
-
77951118936
-
Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis
-
COI: 1:CAS:528:DC%2BC3cXkslaru7w%3D, PID: 20393566
-
Gupta RA, Shah N, Wang KC, Kim J, Horlings HM, Wong DJ, et al. Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis. Nature. 2010;464(7291):1071–6. doi:10.1038/nature08975.
-
(2010)
Nature
, vol.464
, Issue.7291
, pp. 1071-1076
-
-
Gupta, R.A.1
Shah, N.2
Wang, K.C.3
Kim, J.4
Horlings, H.M.5
Wong, D.J.6
-
79
-
-
84899157532
-
Downregulation of BRAF activated non-coding RNA is associated with poor prognosis for non-small cell lung cancer and promotes metastasis by affecting epithelial-mesenchymal transition
-
PID: 24655544
-
Sun M, Liu XH, Wang KM, Nie FQ, Kong R, Yang JS, et al. Downregulation of BRAF activated non-coding RNA is associated with poor prognosis for non-small cell lung cancer and promotes metastasis by affecting epithelial-mesenchymal transition. Molecular cancer. 2014;13:68. doi:10.1186/1476-4598-13-68.
-
(2014)
Molecular cancer.
, vol.13
, pp. 68
-
-
Sun, M.1
Liu, X.H.2
Wang, K.M.3
Nie, F.Q.4
Kong, R.5
Yang, J.S.6
-
80
-
-
84876714385
-
Long non-coding RNA H19 increases bladder cancer metastasis by associating with EZH2 and inhibiting E-cadherin expression
-
COI: 1:CAS:528:DC%2BC3sXisVSqtLg%3D, PID: 23354591
-
Luo M, Li Z, Wang W, Zeng Y, Liu Z, Qiu J. Long non-coding RNA H19 increases bladder cancer metastasis by associating with EZH2 and inhibiting E-cadherin expression. Cancer Lett. 2013;333(2):213–21. doi:10.1016/j.canlet.2013.01.033.
-
(2013)
Cancer Lett
, vol.333
, Issue.2
, pp. 213-221
-
-
Luo, M.1
Li, Z.2
Wang, W.3
Zeng, Y.4
Liu, Z.5
Qiu, J.6
-
81
-
-
84881017449
-
Genomic instability may originate from imatinib-refractory chronic myeloid leukemia stem cells
-
COI: 1:CAS:528:DC%2BC3sXot1Kjt7g%3D, PID: 23543457
-
Bolton-Gillespie E, Schemionek M, Klein HU, Flis S, Hoser G, Lange T, et al. Genomic instability may originate from imatinib-refractory chronic myeloid leukemia stem cells. Blood. 2013;121(20):4175–83. doi:10.1182/blood-2012-11-466938.
-
(2013)
Blood
, vol.121
, Issue.20
, pp. 4175-4183
-
-
Bolton-Gillespie, E.1
Schemionek, M.2
Klein, H.U.3
Flis, S.4
Hoser, G.5
Lange, T.6
-
82
-
-
84860819704
-
Rac2-MRC-cIII-generated ROS cause genomic instability in chronic myeloid leukemia stem cells and primitive progenitors
-
COI: 1:CAS:528:DC%2BC38XmvV2rt74%3D, PID: 22411871
-
Nieborowska-Skorska M, Kopinski PK, Ray R, Hoser G, Ngaba D, Flis S, et al. Rac2-MRC-cIII-generated ROS cause genomic instability in chronic myeloid leukemia stem cells and primitive progenitors. Blood. 2012;119(18):4253–63. doi:10.1182/blood-2011-10-385658.
-
(2012)
Blood
, vol.119
, Issue.18
, pp. 4253-4263
-
-
Nieborowska-Skorska, M.1
Kopinski, P.K.2
Ray, R.3
Hoser, G.4
Ngaba, D.5
Flis, S.6
-
83
-
-
80755141289
-
Methylation of cancer-stem-cell-associated Wnt target genes predicts poor prognosis in colorectal cancer patients
-
de Sousa EMF, Colak S, Buikhuisen J, Koster J, Cameron K, de Jong JH, et al. Methylation of cancer-stem-cell-associated Wnt target genes predicts poor prognosis in colorectal cancer patients. Cell Stem Cell. 2011;9(5):476–85. doi:10.1016/j.stem.2011.10.008.
-
(2011)
Cell Stem Cell
, vol.9
, Issue.5
, pp. 476-485
-
-
de Sousa, E.M.F.1
Colak, S.2
Buikhuisen, J.3
Koster, J.4
Cameron, K.5
de Jong, J.H.6
-
84
-
-
65349162096
-
Let-7 and miR-200 microRNAs: guardians against pluripotency and cancer progression
-
COI: 1:CAS:528:DC%2BD1MXlvFWis7k%3D
-
Peter ME. Let-7 and miR-200 microRNAs: guardians against pluripotency and cancer progression. Cell Cycle (Georgetown, Tex). 2009;8(6):843–52.
-
(2009)
Cell Cycle (Georgetown, Tex)
, vol.8
, Issue.6
, pp. 843-852
-
-
Peter, M.E.1
-
85
-
-
78549261109
-
Double-negative feedback loop between reprogramming factor LIN28 and microRNA let-7 regulates aldehyde dehydrogenase 1-positive cancer stem cells
-
COI: 1:CAS:528:DC%2BC3cXhsVWmsLnF, PID: 21045151
-
Yang X, Lin X, Zhong X, Kaur S, Li N, Liang S, et al. Double-negative feedback loop between reprogramming factor LIN28 and microRNA let-7 regulates aldehyde dehydrogenase 1-positive cancer stem cells. Cancer Res. 2010;70(22):9463–72. doi:10.1158/0008-5472.CAN-10-2388.
-
(2010)
Cancer Res
, vol.70
, Issue.22
, pp. 9463-9472
-
-
Yang, X.1
Lin, X.2
Zhong, X.3
Kaur, S.4
Li, N.5
Liang, S.6
-
86
-
-
84863343713
-
Loss of let-7 up-regulates EZH2 in prostate cancer consistent with the acquisition of cancer stem cell signatures that are attenuated by BR-DIM
-
COI: 1:CAS:528:DC%2BC38XkvVyitb8%3D, PID: 22442719
-
Kong D, Heath E, Chen W, Cher ML, Powell I, Heilbrun L, et al. Loss of let-7 up-regulates EZH2 in prostate cancer consistent with the acquisition of cancer stem cell signatures that are attenuated by BR-DIM. PLoS One. 2012;7(3):e33729. doi:10.1371/journal.pone.0033729.
-
(2012)
PLoS One
, vol.7
, Issue.3
, pp. 33729
-
-
Kong, D.1
Heath, E.2
Chen, W.3
Cher, M.L.4
Powell, I.5
Heilbrun, L.6
-
87
-
-
84866665586
-
Tumor stem cell antigens as consolidative active specific immunotherapy: a randomized phase II trial of dendritic cells versus tumor cells in patients with metastatic melanoma
-
PID: 22996370
-
Dillman RO, Cornforth AN, Depriest C, McClay EF, Amatruda TT, de Leon C, et al. Tumor stem cell antigens as consolidative active specific immunotherapy: a randomized phase II trial of dendritic cells versus tumor cells in patients with metastatic melanoma. J Immunother. 2012;35(8):641–9. doi:10.1097/CJI.0b013e31826f79c8.
-
(2012)
J Immunother
, vol.35
, Issue.8
, pp. 641-649
-
-
Dillman, R.O.1
Cornforth, A.N.2
Depriest, C.3
McClay, E.F.4
Amatruda, T.T.5
de Leon, C.6
-
88
-
-
84891852738
-
Self-renewal as a therapeutic target in human colorectal cancer
-
COI: 1:CAS:528:DC%2BC3sXhvVGqs7rJ, PID: 24292392
-
Kreso A, van Galen P, Pedley NM, Lima-Fernandes E, Frelin C, Davis T, et al. Self-renewal as a therapeutic target in human colorectal cancer. Nat Med. 2014;20(1):29–36. doi:10.1038/nm.3418.
-
(2014)
Nat Med
, vol.20
, Issue.1
, pp. 29-36
-
-
Kreso, A.1
van Galen, P.2
Pedley, N.M.3
Lima-Fernandes, E.4
Frelin, C.5
Davis, T.6
-
89
-
-
84877150506
-
Cancer metabolism, stemness and tumor recurrence: MCT1 and MCT4 are functional biomarkers of metabolic symbiosis in head and neck cancer
-
COI: 1:CAS:528:DC%2BC3sXovFelsrg%3D
-
Curry JM, Tuluc M, Whitaker-Menezes D, Ames JA, Anantharaman A, Butera A, et al. Cancer metabolism, stemness and tumor recurrence: MCT1 and MCT4 are functional biomarkers of metabolic symbiosis in head and neck cancer. Cell Cycle (Georgetown, Tex). 2013;12(9):1371–84. doi:10.4161/cc.24092.
-
(2013)
Cell Cycle (Georgetown, Tex)
, vol.12
, Issue.9
, pp. 1371-1384
-
-
Curry, J.M.1
Tuluc, M.2
Whitaker-Menezes, D.3
Ames, J.A.4
Anantharaman, A.5
Butera, A.6
-
90
-
-
36749080325
-
Roles of human epidermal growth factor receptor 2, c-jun NH2-terminal kinase, phosphoinositide 3-kinase, and p70 S6 kinase pathways in regulation of cyclin G2 expression in human breast cancer cells
-
COI: 1:CAS:528:DC%2BD2sXhtlWkt7nP, PID: 18025271
-
Le XF, Arachchige-Don AS, Mao W, Horne MC, Bast RC Jr. Roles of human epidermal growth factor receptor 2, c-jun NH2-terminal kinase, phosphoinositide 3-kinase, and p70 S6 kinase pathways in regulation of cyclin G2 expression in human breast cancer cells. Mol Cancer Ther. 2007;6(11):2843–57. doi:10.1158/1535-7163.MCT-07-0109.
-
(2007)
Mol Cancer Ther
, vol.6
, Issue.11
, pp. 2843-2857
-
-
Le, X.F.1
Arachchige-Don, A.S.2
Mao, W.3
Horne, M.C.4
Bast, R.C.5
-
91
-
-
84887178635
-
mTOR activation in immature cells of primary nasopharyngeal carcinoma and anti-tumor effect of rapamycin in vitro and in vivo
-
COI: 1:CAS:528:DC%2BC3sXhtlCgt77M, PID: 23933173
-
Yang C, Peng J, Jiang W, Zhang Y, Chen X, Wu X, et al. mTOR activation in immature cells of primary nasopharyngeal carcinoma and anti-tumor effect of rapamycin in vitro and in vivo. Cancer Lett. 2013;341(2):186–94. doi:10.1016/j.canlet.2013.08.004.
-
(2013)
Cancer Lett
, vol.341
, Issue.2
, pp. 186-194
-
-
Yang, C.1
Peng, J.2
Jiang, W.3
Zhang, Y.4
Chen, X.5
Wu, X.6
-
92
-
-
84867917224
-
Monoclonal antibodies against Lgr5 identify human colorectal cancer stem cells
-
COI: 1:CAS:528:DC%2BC38XhvVWgsbnO
-
Kemper K, Prasetyanti PR, De Lau W, Rodermond H, Clevers H, Medema JP. Monoclonal antibodies against Lgr5 identify human colorectal cancer stem cells. Stem Cells (Dayton, Ohio). 2012;30(11):2378–86. doi:10.1002/stem.1233.
-
(2012)
Stem Cells (Dayton, Ohio)
, vol.30
, Issue.11
, pp. 2378-2386
-
-
Kemper, K.1
Prasetyanti, P.R.2
De Lau, W.3
Rodermond, H.4
Clevers, H.5
Medema, J.P.6
-
93
-
-
49249125421
-
Phase I, pharmacokinetic and pharmacodynamic study of the anti-insulinlike growth factor type 1 Receptor monoclonal antibody CP-751,871 in patients with multiple myeloma
-
COI: 1:CAS:528:DC%2BD1cXptlKgtb8%3D, PID: 18474873
-
Lacy MQ, Alsina M, Fonseca R, Paccagnella ML, Melvin CL, Yin D, et al. Phase I, pharmacokinetic and pharmacodynamic study of the anti-insulinlike growth factor type 1 Receptor monoclonal antibody CP-751,871 in patients with multiple myeloma. J Clin Oncol. 2008;26(19):3196–203. doi:10.1200/jco.2007.15.9319.
-
(2008)
J Clin Oncol
, vol.26
, Issue.19
, pp. 3196-3203
-
-
Lacy, M.Q.1
Alsina, M.2
Fonseca, R.3
Paccagnella, M.L.4
Melvin, C.L.5
Yin, D.6
-
94
-
-
79952284127
-
Hallmarks of cancer: the next generation
-
COI: 1:CAS:528:DC%2BC3MXjsFeqtrk%3D, PID: 21376230
-
Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell. 2011;144(5):646–74. doi:10.1016/j.cell.2011.02.013.
-
(2011)
Cell
, vol.144
, Issue.5
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
95
-
-
84860342715
-
Pancreatic stellate cells form a niche for cancer stem cells and promote their self-renewal and invasiveness
-
COI: 1:CAS:528:DC%2BC38XnsVSqsrY%3D
-
Lonardo E, Frias-Aldeguer J, Hermann PC, Heeschen C. Pancreatic stellate cells form a niche for cancer stem cells and promote their self-renewal and invasiveness. Cell Cycle (Georgetown, Tex). 2012;11(7):1282–90. doi:10.4161/cc.19679.
-
(2012)
Cell Cycle (Georgetown, Tex)
, vol.11
, Issue.7
, pp. 1282-1290
-
-
Lonardo, E.1
Frias-Aldeguer, J.2
Hermann, P.C.3
Heeschen, C.4
-
96
-
-
33846029123
-
A perivascular niche for brain tumor stem cells
-
COI: 1:CAS:528:DC%2BD2sXhtFClsLY%3D, PID: 17222791
-
Calabrese C, Poppleton H, Kocak M, Hogg TL, Fuller C, Hamner B, et al. A perivascular niche for brain tumor stem cells. Cancer Cell. 2007;11(1):69–82. doi:10.1016/j.ccr.2006.11.020.
-
(2007)
Cancer Cell
, vol.11
, Issue.1
, pp. 69-82
-
-
Calabrese, C.1
Poppleton, H.2
Kocak, M.3
Hogg, T.L.4
Fuller, C.5
Hamner, B.6
-
97
-
-
25444495269
-
Opinion: migrating cancer stem cells—an integrated concept of malignant tumour progression
-
COI: 1:CAS:528:DC%2BD2MXpsleksLw%3D, PID: 16148886
-
Brabletz T, Jung A, Spaderna S, Hlubek F, Kirchner T. Opinion: migrating cancer stem cells—an integrated concept of malignant tumour progression. Nat Rev Cancer. 2005;5(9):744–9. doi:10.1038/nrc1694.
-
(2005)
Nat Rev Cancer
, vol.5
, Issue.9
, pp. 744-749
-
-
Brabletz, T.1
Jung, A.2
Spaderna, S.3
Hlubek, F.4
Kirchner, T.5
-
98
-
-
84895740986
-
miR-203 inhibits the proliferation and self-renewal of esophageal cancer stem-like cells by suppressing stem renewal factor Bmi-1
-
COI: 1:CAS:528:DC%2BC2cXjsFGntrg%3D, PID: 24219349
-
Yu X, Jiang X, Li H, Guo L, Jiang W, Lu SH. miR-203 inhibits the proliferation and self-renewal of esophageal cancer stem-like cells by suppressing stem renewal factor Bmi-1. Stem Cells Dev. 2014;23(6):576–85. doi:10.1089/scd.2013.0308.
-
(2014)
Stem Cells Dev
, vol.23
, Issue.6
, pp. 576-585
-
-
Yu, X.1
Jiang, X.2
Li, H.3
Guo, L.4
Jiang, W.5
Lu, S.H.6
-
99
-
-
41649091906
-
The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2
-
COI: 1:CAS:528:DC%2BD1cXksVGktL4%3D, PID: 18381893
-
Park SM, Gaur AB, Lengyel E, Peter ME. The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2. Genes Dev. 2008;22(7):894–907. doi:10.1101/gad.1640608.
-
(2008)
Genes Dev
, vol.22
, Issue.7
, pp. 894-907
-
-
Park, S.M.1
Gaur, A.B.2
Lengyel, E.3
Peter, M.E.4
-
100
-
-
44649163918
-
A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells
-
COI: 1:CAS:528:DC%2BD1cXmsFykt7Y%3D, PID: 18483486
-
Burk U, Schubert J, Wellner U, Schmalhofer O, Vincan E, Spaderna S, et al. A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells. EMBO Rep. 2008;9(6):582–9. doi:10.1038/embor.2008.74.
-
(2008)
EMBO Rep
, vol.9
, Issue.6
, pp. 582-589
-
-
Burk, U.1
Schubert, J.2
Wellner, U.3
Schmalhofer, O.4
Vincan, E.5
Spaderna, S.6
|