Monoclonal antibodies against Lgr5 identify human colorectal cancer stem cells

Stem Cells

Volumn 30, Issue 11, 2012, Pages 2378-2386

  Kemper, Kristel ^a   Prasetyanti, Pramudita R ^a   De Lau, Wim ^b   Rodermond, Hans ^a   Clevers, Hans ^b   Medema, Jan Paul ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

Antibody; Cancer stem cell; Colorectal; Lgr5

Indexed keywords

MONOCLONAL ANTIBODY; PEPTIDES AND PROTEINS; PROTEIN LGR5; UNCLASSIFIED DRUG; WNT PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER STEM CELL; CELL DIFFERENTIATION; COLORECTAL CANCER; DOWN REGULATION; FLUORESCENCE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PROTEIN EXPRESSION;

ANIMALS; ANTIBODIES, MONOCLONAL, MURINE-DERIVED; CELL DIFFERENTIATION; CELL SEPARATION; CELL TRANSFORMATION, NEOPLASTIC; COLORECTAL NEOPLASMS; EPITOPE MAPPING; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE KNOCKDOWN TECHNIQUES; HUMANS; MALE; MICE; MICE, NUDE; MUCIN-2; NEOPLASM TRANSPLANTATION; NEOPLASTIC STEM CELLS; RATS; RECEPTORS, G-PROTEIN-COUPLED; SPHEROIDS, CELLULAR; TUMOR CELLS, CULTURED; TUMOR MARKERS, BIOLOGICAL; WNT SIGNALING PATHWAY;

EID: 84867917224     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.1233     Document Type: Article

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