Identification of pancreatic cancer stem cells and selective toxicity of chemotherapeutic agents

Gastroenterology

Volumn 143, Issue 1, 2012, Pages

  Adikrisna, Rama ^a   Tanaka, Shinji ^a   Muramatsu, Shunsuke ^a   Aihara, Arihiro ^a   Ban, Daisuke ^a   Ochiai, Takanori ^a   Irie, Takumi ^a   Kudo, Atsushi ^a   Nakamura, Noriaki ^a   Yamaoka, Shoji ^a   Arii, Shigeki ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

Flavonoid; Mouse Model; Pancreas; Tumorigenesis

Indexed keywords

ANTINEOPLASTIC AGENT; BETA CATENIN; GEMCITABINE; GREEN FLUORESCENT PROTEIN; ORNITHINE DECARBOXYLASE; PROTEASOME; QUERCETIN; RETROVIRUS VECTOR;

ARTICLE; CANCER CELL; CANCER STEM CELL; CONTROLLED STUDY; DRUG CYTOTOXICITY; ENZYME ACTIVITY; FLOW CYTOMETRY; FLUORESCENCE; HUMAN; HUMAN CELL; LETHALITY; PANCREAS ADENOCARCINOMA; PANCREAS CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR GROWTH;

EID: 84862737662     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2012.03.054     Document Type: Article

References (56)

1. M. Shackleton, E. Quintana, E.R. Fearon Heterogeneity in cancer: cancer stem cells versus clonal evolution Cell 138 2009 822 829
2. J.E. Visvader Cells of origin in cancer Nature 469 2011 314 322
3. T. Reya, S.J. Morrison, M.F. Clarke Stem cells, cancer, and cancer stem cells Nature 414 2001 105 111
4. M. Al-Hajj, M.S. Wicha, A. Benito-Hernandez Prospective identification of tumorigenic breast cancer cells Proc Natl Acad Sci U S A 100 2003 3983 3988
5. S.K. Singh, C. Hawkins, I.D. Clarke Identification of human brain tumour initiating cells Nature 432 2004 396 401
6. + cancer stem cells in human liver cancer Cancer Cell 13 2008 153 166
7. P.C. Hermann, S.L. Huer, T. Herrler Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer Cell Stem Cell 1 2007 313 323
8. R.A. Neumüller, J.A. Knoblich Dividing cellular asymmetry: asymmetric cell division and its implications for stem cells and cancer Genes Dev 23 2009 2675 2699
9. N. Haraguchi, H. Ishii, K. Mimori CD13 is a therapeutic target in human liver cancer stem cells J Clin Invest 120 2010 3326 3339
10. L. Ricci-Vitiani, D.G. Lombardi, E. Pilozzi Identification and expansion of human colon-cancer-initiating cells Nature 445 2007 111 115
11. F. Yu, H. Yao, P. Zhu let-7 regulates self renewal and tumorigenicity of breast cancer cells Cell 131 2007 1109 1123
12. B.B. Zhou, H. Zhang, M. Damelin Tumour-initiating cells: challenges and opportunities for anticancer drug discovery Nat Rev Drug Discov 8 2009 806 823
13. E. Vlashi, K. Kim, C. Lagadec In vivo imaging, tracking, and targeting of cancer stem cells J Natl Cancer Inst 101 2009 350 359
14. M. Bajorek, D. Finley, M.H. Glickman Proteasome disassembly and downregulation is correlated with viability during stationary phase Curr Biol 13 2003 1140 1144
15. M. Hernebring, G. Brolén, H. Agulianiu Elimination of damaged proteins during differentiation of embryonic stem cells Proc Natl Acad Sci U S A 103 2006 7700 7705
16. L. Li, R. Bhatia Stem cell quiescence Clin Cancer Res 17 2011 4936 4941
17. J. Pan, Q. Zhang, Y. Wang 26S proteasome activity is down-regulated in lung cancer stem-like cells propagated in vitro PLoS One 5 2010 e13298
18. S. Achuthan, T.R. Santhoshkumar, J. Prabhakar Drug induced senescence generates chemoresistant stem like cells with low reactive oxygen species J Biol Chem 286 2011 37813 37829
19. E. Vlashi, C. Lagadec, L. Vergnes Metabolic state of glioma stem cells and nontumorigenic cells Proc Natl Acad Sci U S A 108 2011 16062 16067
20. W.G. Kaelin Jr The concept of synthetic lethality in the context of anticancer therapy Nat Rev Cancer 5 2005 689 698
21. A.W. Whitehurst, B.O. Bodemann, J. Cardenas Synthetic lethal screen identification of chemosensitizer loci in cancer cells Nature 446 2007 815 819
22. J.M. Rosen, C.T. Jordan The increasing complexity of the cancer stem cell paradigm Science 324 2009 1670 1673
23. S. Maehara, S. Tanaka, M. Shimada Selenoprotein P, as a predictor for evaluating gemcitabine resistance, in human pancreatic cancer cells Int J Cancer 112 2004 184 189
24. S. Tanaka, S.C. Pero, K. Taguchi Specific peptide ligand for Grb7 signal transduction protein and pancreatic cancer metastasis J Natl Cancer Inst 98 2006 491 498
25. T. Furukawa, W.P. Duguid, L. Rosenberg Long term culture and immortalization of epithelial cells from normal adult human pancreatic ducts by transfection with the E6E7 gene of human papilloma virus 16 Am J Pathol 148 1996 1763 1770
26. H. Ouyang, L.-J. Mou, C. Luk Paradiploid human pancreatic duct epithelial cell lines with near normal phenotype Am J Pathol 157 2000 1623 1631
27. T. Saitoh, A. Tun-Kyi, A. Ryo Negative regulation of interferon- regulatory factor 3-dependent innate antiviral response by the prolyl isomerase Pin1 Nat Immunol 7 2006 598 605
28. A. Chojnacki, S. Weiss Production of neurons, astrocytes and oligodendrocytes from mammalian CNS stem cells Nat Protoc 3 2008 935 940
29. B.A. Reynolds, R.L. Rietze Neural stem cells and neurospheres - re-evaluating the relationship Nat Methods 2 2005 333 336
30. C.H. Park, J.Y. Chang, E.R. Hahm Quercetin, a potent inhibitor against beta-catenin/Tcf signaling in SW480 colon cancer cells Biochem Biophys Res Commun 328 2005 227 234
31. J. Román-Gómez, L. Cordeu, X. Agirre Epigenetic regulation of Wnt-signaling pathway in acute lymphoblastic leukaemia Blood 109 2007 3462 3469
32. T. Reya, H. Clevers Wnt signaling in stem cells and cancer Nature 434 2005 843 850
33. J. Kirshner, K.J. Thulien, L.D. Martin A unique three-dimensional model for evaluating the impact of therapy on multiple myeloma Blood 112 2008 2935 2945
34. J.T. Chang, M.L. Ciocca, I. Kinjyo Asymmetric proteasome segregation as a mechanism for unequal partitioning of the transcription factor T-bet during T lymphocyte division Immunity 34 2011 492 504
35. L.C. Fuentealba, E. Eivers, D. Geissert Asymmetric mitosis: unequal segregation of proteins destined for degradation Proc Natl Acad Sci U S A 34 2011 492 504
36. C. Li, D.G. Heidt, P. Dalerba Identification of pancreatic cancer stem cells Cancer Res 67 2007 1030 1037
37. L.A. Johnston Competitive interactions between cells: death, growth, and geography Science 324 2009 1679 1682
38. A. Ootani, X. Li, E. Sangiorgi Sustained in vitro intestinal epithelial culture within a Wnt-dependent stem cell niche Nat Med 15 2009 701 706
39. K. Ito, R. Bernardi, A. Morotti PML targeting eradicates quiescent leukaemia-initiating cells Nature 453 2008 1072 1078
40. C. Calabrese, H. Poppleton, M. Kocak A perivascular niche for brain tumor stem cells Cancer Cell 11 2007 69 82
41. P.B. Gupta, T.T. Onder, G. Jiang Identification of selective inhibitors of cancer stem cells by high-throughput screening Cell 138 2009 645 659
42. W. Zhou, G. Kallifatidis, B. Baumann Dietary polyphenol quercetin targets pancreatic cancer stem cells Int J Oncol 37 2010 551 561
43. V. Dudeja, M. Mujumdar, P. Phillips Heat shock protein 70 inhibits apoptosis in cancer cells through simultaneous and independent mechanisms Gastroenterology 136 2009 1772 1782
44. C. Chen, J. Zhou, C. Ji Quercetin: a potential drug to reverse multidrug resistance Life Sci 87 2010 333 338
45. S. Tanaka, S. Arii Molecular targeted therapy for hepatocellular carcinoma in the current and potential next strategies J Gastroenterol 46 2011 289 296
46. S.M. Huang, Y.M. Mishina, S. Liu Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling Nature 461 2009 614 620
47. M.G. Hertog, E.J. Feskens, P.C. Hollman Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly Study Lancet 342 1993 1007 1011
48. D. Labbé, M. Provençal, S. Lamy The flavonols quercetin, kaempferolm and myricetin inhibit hepatocyte growth factor-induced medulloblastoma cell migration J Nutr 139 2009 646 652
49. E. Owusu-Ansah, U. Banerjee Reactive oxygen species prime Drosophila haematopoietic progenitors for differentiation Nature 461 2009 537 541
50. K.D. Bunting ABC transporters as phenotypic markers and functional regulators of stem cells Stem Cells 20 2002 11 20
51. Y. Li, A. Li, M. Glas c-Met signaling induces a reprogramming network and supports the glioblastoma stem-like phenotype Proc Natl Acad Sci U S A 108 2011 9951 9956
52. C. Li, J.J. Wu, M. Hynes c-Met is a marker of pancreatic cancer stem cells and therapeutic target Gastroenterology 141 2011 2218 2227
53. U. Nöthlings, S.P. Murphy, L.R. Wilkens Flavonols and pancreatic cancer risk: the multiethnic cohort study Am J Epidemiol 166 2007 924 931
54. S. Raimondi, P. Maisonneuve, A.B. Lowenfels Epidemiology of pancreatic cancer: an overview Nat Rev Gastroenterol Hepatol 6 2009 699 708
55. M. Hidalgo Pancreatic cancer N Engl J Med 362 2010 1605 1617
56. Z.A. Rasheed, J. Yang, Q. Wang Prognostic significance of tumorigenic cells with mesenchymal features in pancreatic adenocarcinoma J Natl Cancer Inst 102 2010 340 351