XPharmacological inactivation of Skp2 SCF ubiquitin ligase restricts cancer stem cell traits and cancer progression

Cell

Volumn 154, Issue 3, 2013, Pages

  Chan, Chia Hsin ^a   Morrow, John Kenneth ^a,b   Li, Chien Feng ^c,d   Gao, Yuan ^a,b   Jin, Guoxiang ^a   Moten, Asad ^a,e   Stagg, Loren J ^a   Ladbury, John E ^a   Cai, Zhen ^a   Xu, Dazhi ^a   Logothetis, Christopher J ^a   Hung, Mien Chie ^a,b,f   Zhang, Shuxing ^a,b   Lin, Hui Kuan ^a,b  

^a UNIVERSITY OF TEXAS   (United States)

^b UNIVERSITY OF TEXAS   (United States)

^c Chi Mei Foundational Medical Center   (Taiwan)

^d NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

^e HARVARD UNIVERSITY   (United States)

^f CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CYCLOPHOSPHAMIDE; DOXORUBICIN; LIGASE INHIBITOR; PROTEIN KINASE B; PROTEIN P53; S PHASE KINASE ASSOCIATED PROTEIN 2; SKP1 PROTEIN; SKP2 INHIBITOR; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

AEROBIC METABOLISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER GROWTH; CANCER STEM CELL; CELL MATURATION; CELL METABOLISM; CELL POPULATION; CELL RENEWAL; CELL SURVIVAL; COMPLEX FORMATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG DETERMINATION; DRUG DOSE COMPARISON; DRUG POTENCY; DRUG POTENTIATION; DRUG PROTEIN BINDING; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME INHIBITION; GLYCOLYSIS; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN TISSUE; IN VITRO STUDY; LUNG CANCER; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN PROTEIN INTERACTION; STRUCTURE ACTIVITY RELATION;

ANIMALIA;

EID: 84881192827     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2013.06.048     Document Type: Article

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