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Chemical Communications

Volumn 51, Issue 35, 2015, Pages 7478-7481

Repurposing de novo designed entities reveals phosphodiesterase 3B and cathepsin L modulators

(6) Rodrigues, Tiago a Lin, Yen Chu a Hartenfeller, Markus a,b Renner, Steffen b Lim, Yi Fan a Schneider, Gisbert a

a ETH ZURICH (Switzerland)

b NOVARTIS PHARMA AG (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

AMPRENAVIR; CATHEPSIN L; COLLAGENASE 3; INTERSTITIAL COLLAGENASE; MACROPHAGE ELASTASE; MATRIX METALLOPROTEINASE INHIBITOR; NEUTROPHIL COLLAGENASE; PHOSPHODIESTERASE III; PHOSPHODIESTERASE III INHIBITOR; PHOSPHODIESTERASE IIIB; PIMOBENDAN; STROMELYSIN; UNCLASSIFIED DRUG; PROTEIN BINDING; PROTEINASE INHIBITOR;

ALLOSTERISM; AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; BIOLOGICAL ACTIVITY; COLORIMETRY; COMPUTER PROGRAM; CYTOTOXICITY; DIASTEREOISOMER; DYNAMIC LIGHT SCATTERING; ENZYME SPECIFICITY; LIGHT SCATTERING; LIPOLYSIS; METABOLIC REGULATION; PHARMACOPHORE; PREDICTION; QUANTITATIVE ANALYSIS; STRUCTURE ACTIVITY RELATION; ANTAGONISTS AND INHIBITORS; CHEMISTRY; COMPUTER SIMULATION; METABOLISM;

CATHEPSIN L; COMPUTER SIMULATION; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 3; PHOSPHODIESTERASE 3 INHIBITORS; PROTEASE INHIBITORS; PROTEIN BINDING; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84928339106 PISSN: 13597345 EISSN: 1364548X Source Type: Journal
DOI: 10.1039/c5cc01376c Document Type: Article

Times cited : (7)

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