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Volumn 4, Issue 3, 2013, Pages 1229-1233

De novo design and optimization of Aurora A kinase inhibitors

(7) Rodrigues, Tiago a Roudnicky, Filip a Koch, Christian P a Kudoh, Takayuki a,b Reker, Daniel a Detmar, Michael a Schneider, Gisbert a

a ETH ZURICH (Switzerland)

b OKAYAMA UNIVERSITY (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL OPTIMIZATIONS; DE NOVO DESIGN; DE NOVO LIGAND DESIGNS; INHIBITORY ACTIVITY; KINASE INHIBITORS; LEAD STRUCTURE; NEW CHEMICAL ENTITIES; PHARMACEUTICAL INDUSTRY;

LIGANDS; OPTIMIZATION; SOFTWARE TESTING;

ENZYMES;

EID: 84876736732 PISSN: 20416520 EISSN: 20416539 Source Type: Journal
DOI: 10.1039/c2sc21842a Document Type: Article

Times cited : (22)

References (34)

1
- 80052831391
- Y. L. Bennani Drug Discovery Today 2011 16 779 792
- (2011) Drug Discovery Today , vol.16 , pp. 779-792
- Bennani, Y.L.¹

2
- 79957889347
- F. Pammolli L. Magazzini M. Riccaboni Nat. Rev. Drug Discovery 2011 10 428 438
- (2011) Nat. Rev. Drug Discovery , vol.10 , pp. 428-438
- Pammolli, F.¹ Magazzini, L.² Riccaboni, M.³

3
- 23844449940
- G. Schneider U. Fechner Nat. Rev. Drug Discovery 2005 4 649 663
- (2005) Nat. Rev. Drug Discovery , vol.4 , pp. 649-663
- Schneider, G.¹ Fechner, U.²

4
- 80053593946
- M. Hartenfeller and G. Schneider, WIREs Comput. Mol. Sci., 2011, vol. 1, pp. 742-759
- (2011) WIREs Comput. Mol. Sci. , vol.1 , pp. 742-759
- Hartenfeller, M.¹ Schneider, G.²

5
- 84857448743
- G. Schneider J. Comput.-Aided Mol. Des. 2012 26 115 120
- (2012) J. Comput.-Aided Mol. Des. , vol.26 , pp. 115-120
- Schneider, G.¹

6
- 78650191703
- K. Hasegawa M. Keiya K. Funatsu Mol. Inf. 2010 29 793 800
- (2010) Mol. Inf. , vol.29 , pp. 793-800
- Hasegawa, K.¹ Keiya, M.² Funatsu, K.³

7
- 79959646086
- M. L. Iacono V. Monica S. Saviozzi P. Ceppi E. Bracco M. Papotti G. V. Scagliotti J. Transl. Med. 2011 9 100
- (2011) J. Transl. Med. , vol.9 , pp. 100
- Iacono, M.L.¹ Monica, V.² Saviozzi, S.³ Ceppi, P.⁴ Bracco, E.⁵ Papotti, M.⁶ Scagliotti, G.V.⁷

8
- 0033135640
- T. Tanaka M. Kimura K. Matsunaga D. Fukada H. Mori Y. Okano Cancer Res. 1999 59 2041 2044
- (1999) Cancer Res. , vol.59 , pp. 2041-2044
- Tanaka, T.¹ Kimura, M.² Matsunaga, K.³ Fukada, D.⁴ Mori, H.⁵ Okano, Y.⁶

9
- 0032100685
- J. R. Bischoff L. Anderson Y. Zhu K. Mossie L. Ng B. Souza B. Schryver P. Flanagan F. Clairvoyant C. Ginther C. S. M. Chan M. Novotny D. J. Slamon G. D. Plowman EMBO J. 1998 17 3052 3065
- (1998) EMBO J. , vol.17 , pp. 3052-3065
- Bischoff, J.R.¹ Anderson, L.² Zhu, Y.³ Mossie, K.⁴ Ng, L.⁵ Souza, B.⁶ Schryver, B.⁷ Flanagan, P.⁸ Clairvoyant, F.⁹ Ginther, C.¹⁰ Chan, C.S.M.¹¹ Novotny, M.¹² Slamon, D.J.¹³ Plowman, G.D.¹⁴

10
- 2342639645
- E. A. Harrington D. Bebbington J. Moore R. K. Rasmussen A. O. Ajose-Adeogun T. Nakayama J. A. Graham C. Demur T. Hercend A. Diu-Hercend M. Su J. M. C. Golec K. M. Miller Nat. Med. 2004 10 262 267
- (2004) Nat. Med. , vol.10 , pp. 262-267
- Harrington, E.A.¹ Bebbington, D.² Moore, J.³ Rasmussen, R.K.⁴ Ajose-Adeogun, A.O.⁵ Nakayama, T.⁶ Graham, J.A.⁷ Demur, C.⁸ Hercend, T.⁹ Diu-Hercend, A.¹⁰ Su, M.¹¹ Golec, J.M.C.¹² Miller, K.M.¹³

11
- 84861142957
- M. Hartenfeller H. Zettl M. Walter M. Rupp F. Reisen E. Proschak S. Weggen H. Stark G. Schneider PLoS Comput. Biol. 2012 8 e1002380
- (2012) PLoS Comput. Biol. , vol.8 , pp. 1002380
- Hartenfeller, M.¹ Zettl, H.² Walter, M.³ Rupp, M.⁴ Reisen, F.⁵ Proschak, E.⁶ Weggen, S.⁷ Stark, H.⁸ Schneider, G.⁹

12
- 84876480311
- 10.1002/anie.201206897
- B. Spänkuch S. Keppner L. Lange T. Rodrigues H. Zettl C. P. Koch M. Reutlinger M. Hartenfeller P. Schneider G. Schneider Angew. Chem., Int. Ed. 2013 10.1002/anie.201206897
- (2013) Angew. Chem., Int. Ed.
- Spänkuch, B.¹ Keppner, S.² Lange, L.³ Rodrigues, T.⁴ Zettl, H.⁵ Koch, C.P.⁶ Reutlinger, M.⁷ Hartenfeller, M.⁸ Schneider, P.⁹ Schneider, G.¹⁰

13
- 84861495297
- M. Hartenfeller M. Eberle P. Meier C. Nieto-Oberhuber K.-H. Altmann G. Schneider E. Jacoby S. Renner J. Chem. Inf. Model. 2012 52 1167 1178
- (2012) J. Chem. Inf. Model. , vol.52 , pp. 1167-1178
- Hartenfeller, M.¹ Eberle, M.² Meier, P.³ Nieto-Oberhuber, C.⁴ Altmann, K.-H.⁵ Schneider, G.⁶ Jacoby, E.⁷ Renner, S.⁸

14
- 52949141884
- B. Zhao A. Smallwood J. Yang K. Koretke K. Nurse A. Calamari R. B. Kirkpatrick Z. Lai Protein Sci. 2008 17 1791 1797
- (2008) Protein Sci. , vol.17 , pp. 1791-1797
- Zhao, B.¹ Smallwood, A.² Yang, J.³ Koretke, K.⁴ Nurse, K.⁵ Calamari, A.⁶ Kirkpatrick, R.B.⁷ Lai, Z.⁸

15
- 0028854034
- G. Jones P. Willett R. C. Glen J. Mol. Biol. 1995 245 43 53
- (1995) J. Mol. Biol. , vol.245 , pp. 43-53
- Jones, G.¹ Willett, P.² Glen, R.C.³

16
- 84859831259
- M. L. Curtin R. R. Frey H. R. Heyman N. B. Soni P. A. Marcotte L. J. Pease K. B. Glaser T. J. Magoc P. Tapang D. H. Albert D. J. Osterling A. M. Olson J. J. Bouska Z. Guan L. C. Preusser J. S. Polakowski K. D. Stewart C. Tse S. K. Davidsen M. R. Michaelides Bioorg. Med. Chem. Lett. 2012 22 3208 3212
- (2012) Bioorg. Med. Chem. Lett. , vol.22 , pp. 3208-3212
- Curtin, M.L.¹ Frey, R.R.² Heyman, H.R.³ Soni, N.B.⁴ Marcotte, P.A.⁵ Pease, L.J.⁶ Glaser, K.B.⁷ Magoc, T.J.⁸ Tapang, P.⁹ Albert, D.H.¹⁰ Osterling, D.J.¹¹ Olson, A.M.¹² Bouska, J.J.¹³ Guan, Z.¹⁴ Preusser, L.C.¹⁵ Polakowski, J.S.¹⁶ Stewart, K.D.¹⁷ Tse, C.¹⁸ Davidsen, S.K.¹⁹ Michaelides, M.R.²⁰ more..

17
- 80051943502
- L. Zhang J. Fan J.-H. Chong A. Cesena B. Y. Y. Tam C. Gilson C. Boykin D. Wang D. Aivazian D. Marcotte G. Xiao J.-Y. L. Brazidec J. Piao K. Lundgren K. Hong K. Vu K. Nguyen L.-S. Gan L. Silvian L. Ling M. Teng M. Reff N. Takeda N. Timple Q. Wang R. Morena S. Khan S. Zhao T. Li W.-C. Lee A. G. Taveras J. Chao Bioorg. Med. Chem. Lett. 2011 21 5633 5637
- (2011) Bioorg. Med. Chem. Lett. , vol.21 , pp. 5633-5637
- Zhang, L.¹ Fan, J.² Chong, J.-H.³ Cesena, A.⁴ Tam, B.Y.Y.⁵ Gilson, C.⁶ Boykin, C.⁷ Wang, D.⁸ Aivazian, D.⁹ Marcotte, D.¹⁰ Xiao, G.¹¹ Brazidec, J.-Y.L.¹² Piao, J.¹³ Lundgren, K.¹⁴ Hong, K.¹⁵ Vu, K.¹⁶ Nguyen, K.¹⁷ Gan, L.-S.¹⁸ Silvian, L.¹⁹ Ling, L.²⁰ more..

18
- 77956652574
- S. Bindi D. Fancelli C. Alli D. Berta J. A. Bertrand A. D. Cameron P. Cappella P. Carpinelli G. Cervi V. Croci M. D'Anello B. Forte M. L. Giorgini A. Marsiglio J. Moll E. Pesenti V. Pittalà M. Pulici F. Riccardi-Sirtori F. Roletto C. Soncini P. Storici M. Varasi D. Volpi P. Zugnoni P. Vianello Bioorg. Med. Chem. 2010 18 7113 7120
- (2010) Bioorg. Med. Chem. , vol.18 , pp. 7113-7120
- Bindi, S.¹ Fancelli, D.² Alli, C.³ Berta, D.⁴ Bertrand, J.A.⁵ Cameron, A.D.⁶ Cappella, P.⁷ Carpinelli, P.⁸ Cervi, G.⁹ Croci, V.¹⁰ D'Anello, M.¹¹ Forte, B.¹² Giorgini, M.L.¹³ Marsiglio, A.¹⁴ Moll, J.¹⁵ Pesenti, E.¹⁶ Pittalà, V.¹⁷ Pulici, M.¹⁸ Riccardi-Sirtori, F.¹⁹ Roletto, F.²⁰ more..

19
- 33748299545
- S. L. Warner S. Bashyam H. Vankayalapati D. J. Bearss H. Han D. D. V. Hoff L. H. Hurley Mol. Cancer Ther. 2006 5 1764 1773
- (2006) Mol. Cancer Ther. , vol.5 , pp. 1764-1773
- Warner, S.L.¹ Bashyam, S.² Vankayalapati, H.³ Bearss, D.J.⁴ Han, H.⁵ Hoff, D.D.V.⁶ Hurley, L.H.⁷

20
- 85032996208
- G. Hinton and S. T. Roweis, Adv. Neural Inf. Proc. Syst., 2002, vol. 15, pp. 833-840
- (2002) Adv. Neural Inf. Proc. Syst. , vol.15 , pp. 833-840
- Hinton, G.¹ Roweis, S.T.²

21
- 80755125565
- T. Anastassiadis S. W. Deacon K. Devarajan H. Ma J. R. Peterson Nat. Biotechnol. 2011 29 1039 1045
- (2011) Nat. Biotechnol. , vol.29 , pp. 1039-1045
- Anastassiadis, T.¹ Deacon, S.W.² Devarajan, K.³ Ma, H.⁴ Peterson, J.R.⁵

22
- 0033523672
- G. Schneider W. Neidhart T. Giller G. Schmid Angew. Chem., Int. Ed. 1999 38 2894 2896
- (1999) Angew. Chem., Int. Ed. , vol.38 , pp. 2894-2896
- Schneider, G.¹ Neidhart, W.² Giller, T.³ Schmid, G.⁴

23
- 33747479974
- H. Steinhaus Bull. Acad. Polon. Sci. 1956 1 801 804
- (1956) Bull. Acad. Polon. Sci. , vol.1 , pp. 801-804
- Steinhaus, H.¹

24
- 0023375195
- N. Saitou M. Nei Mol. Biol. Evol. 1987 4 406 425
- (1987) Mol. Biol. Evol. , vol.4 , pp. 406-425
- Saitou, N.¹ Nei, M.²

25
- 80053305462
- T. Cheng Q. Li Y. Wang S. H. Bryant J. Chem. Inf. Model. 2011 51 2440 2448
- (2011) J. Chem. Inf. Model. , vol.51 , pp. 2440-2448
- Cheng, T.¹ Li, Q.² Wang, Y.³ Bryant, S.H.⁴

26
- 36148943501
- P. P. Graczyk J. Med. Chem. 2007 50 5773 5779
- (2007) J. Med. Chem. , vol.50 , pp. 5773-5779
- Graczyk, P.P.¹

27
- 60549088370
- S. Howard V. Berdini J. A. Boulstridge M. G. Carr D. M. Cross J. Curry L. A. Devine T. R. Early L. Fazal A. L. Gill M. Heathcote S. Maman J. E. Matthews R. L. McMenamin E. F. Navarro M. A. O'Brien M. O'Reilly D. C. Rees M. Reule D. Tisi G. Williams M. Vinkovic P. G. Wyatt J. Med. Chem. 2009 52 379 388
- (2009) J. Med. Chem. , vol.52 , pp. 379-388
- Howard, S.¹ Berdini, V.² Boulstridge, J.A.³ Carr, M.G.⁴ Cross, D.M.⁵ Curry, J.⁶ Devine, L.A.⁷ Early, T.R.⁸ Fazal, L.⁹ Gill, A.L.¹⁰ Heathcote, M.¹¹ Maman, S.¹² Matthews, J.E.¹³ McMenamin, R.L.¹⁴ Navarro, E.F.¹⁵ O'Brien, M.A.¹⁶ O'Reilly, M.¹⁷ Rees, D.C.¹⁸ Reule, M.¹⁹ Tisi, D.²⁰ more..

28
- 0002917248
- J. W. Bae Y. J. Cho S. H. Lee C.-O. M. Yoon C. M. Yoon Chem. Commun. 2000 1857 1858
- (2000) Chem. Commun. , pp. 1857-1858
- Bae, J.W.¹ Cho, Y.J.² Lee, S.H.³ Yoon, C.-O.M.⁴ Yoon, C.M.⁵

29
- 35748934487
- P. D. Leeson B. Springthorpe Nat. Rev. Drug Discovery 2007 6 881 890
- (2007) Nat. Rev. Drug Discovery , vol.6 , pp. 881-890
- Leeson, P.D.¹ Springthorpe, B.²

30
- 61649109015
- G. M. Keserü G. M. Makara Nat. Rev. Drug Discovery 2009 8 203 212
- (2009) Nat. Rev. Drug Discovery , vol.8 , pp. 203-212
- Keserü, G.M.¹ Makara, G.M.²

31
- 84860359784
- M. M. Hann G. M. Keserü Nat. Rev. Drug Discovery 2012 11 355 365
- (2012) Nat. Rev. Drug Discovery , vol.11 , pp. 355-365
- Hann, M.M.¹ Keserü, G.M.²

32
- 67650085841
- J. W. M. Nissink J. Chem. Inf. Model. 2009 49 1617 1622
- (2009) J. Chem. Inf. Model. , vol.49 , pp. 1617-1622
- Nissink, J.W.M.¹

33
- 43049088827
- C. H. Reynolds B. A. Tounge S. D. Bembenek J. Med. Chem. 2008 51 2432 2438
- (2008) J. Med. Chem. , vol.51 , pp. 2432-2438
- Reynolds, C.H.¹ Tounge, B.A.² Bembenek, S.D.³

34
- 51649095478
- Y. Nadler R. L. Camp C. Schwartz D. L. Rimm H. M. Kluger Clin. Cancer Res. 2008 14 4455 4462
- (2008) Clin. Cancer Res. , vol.14 , pp. 4455-4462
- Nadler, Y.¹ Camp, R.L.² Schwartz, C.³ Rimm, D.L.⁴ Kluger, H.M.⁵

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