Cathepsin-L ameliorates cardiac hypertrophy through activation of the autophagy-lysosomal dependent protein processing pathways.

Journal of the American Heart Association

Volumn 2, Issue 2, 2013, Pages

  Sun, Mei ^a   Ouzounian, Maral ^b   de Couto, Geoffrey ^b   Chen, Manyin ^b   Yan, Ran ^b   Fukuoka, Masahiro ^b   Li, Guohua ^b   Moon, Mark ^b   Liu, Youan ^b   Gramolini, Anthony ^b   Wells, George J ^b   Liu, Peter P ^b  

^a TORONTO GENERAL HOSPITAL   (Canada)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CATHEPSIN L; CTSL PROTEIN, MOUSE; ENDOPLASMIN; HEAT SHOCK PROTEIN; MEMBRANE PROTEIN; MOLECULAR CHAPERONE GRP78; UBIQUITIN PROTEIN LIGASE; UBIQUITINATED PROTEIN;

ANIMAL; APOPTOSIS; ARTICLE; AUTOPHAGY; CARDIOMEGALY; CELL CULTURE; CELL SURVIVAL; DISEASE MODEL; ENDOPLASMIC RETICULUM; ENZYME ASSAY; ENZYMOLOGY; GENETICS; HEART MUSCLE CELL; HEART VENTRICLE REMODELING; LYSOSOME; MALE; METABOLISM; MOUSE; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PHAGOSOME; PHYSIOLOGY; PROTEIN DEGRADATION; PROTEIN PROCESSING;

ANIMALS; APOPTOSIS; AUTOPHAGY; CARDIOMEGALY; CATHEPSIN L; CELL SURVIVAL; CELLS, CULTURED; DISEASE MODELS, ANIMAL; ENDOPLASMIC RETICULUM; ENZYME ASSAYS; HEAT-SHOCK PROTEINS; LYSOSOMES; MALE; MEMBRANE GLYCOPROTEINS; MICE; MYOCYTES, CARDIAC; OXIDATIVE STRESS; PHAGOSOMES; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEOLYSIS; UBIQUITIN-PROTEIN LIGASE COMPLEXES; UBIQUITINATED PROTEINS; VENTRICULAR REMODELING;

EID: 84884371619     PISSN: None     EISSN: 20479980     Source Type: None    
DOI: 10.1161/JAHA.113.000191     Document Type: Article

References (0)