Bloom's Syndrome Helicase and Mus81 are Required to Induce Transient Double-strand DNA Breaks in Response to DNA Replication Stress

Journal of Molecular Biology

Volumn 375, Issue 4, 2008, Pages 1152-1164

  Shimura, Tsutomu ^a,b   Torres, Michael J ^a   Martin, Melvenia M ^a   Rao, V Ashutosh ^a   Pommier, Yves ^a   Katsura, Mari ^c   Miyagawa, Kiyoshi ^c   Aladjem, Mirit I ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b TOHOKU UNIVERSITY   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

Author keywords

aphidicolin; ATR, double strand breaks; BLM; Mus81; replication fork blockage

Indexed keywords

ATR PROTEIN; BLOOM SYNDROME HELICASE; CYCLINE; DNA DIRECTED DNA POLYMERASE ALPHA; DOUBLE STRANDED DNA; NUCLEASE; PROTEIN MUS81; UNCLASSIFIED DRUG;

ARTICLE; CELL CYCLE; DISSOCIATION; DNA DAMAGE; DNA REPAIR; DNA REPLICATION; DNA STRAND BREAKAGE; DNA SYNTHESIS; EXPOSURE; PRIORITY JOURNAL; PROTEIN DNA BINDING; STRESS;

ATAXIA TELANGIECTASIA;

EID: 37349039649     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2007.11.006     Document Type: Article

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