Mutant Huntingtin promotes autonomous microglia activation via myeloid lineage-determining factors

Nature Neuroscience

Volumn 17, Issue 4, 2014, Pages 513-521

  Crotti, Andrea ^a   Benner, Christopher ^b   Kerman, Bilal E ^b   Gosselin, David ^a   Lagier Tourenne, Clotilde ^c,d   Zuccato, Chiara ^e   Cattaneo, Elena ^e   Gage, Fred H ^b   Cleveland, Don W ^a,d   Glass, Christopher K ^a,f  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d LUDWIG INSTITUTE FOR CANCER RESEARCH   (United States)

^e UNIVERSITY OF MILAN   (Italy)

^f UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN ALPHA; CCAAT ENHANCER BINDING PROTEIN BETA; HUNTINGTIN; MUTANT PROTEIN; TRANSCRIPTION FACTOR PU 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; EX VIVO STUDY; GENE EXPRESSION; HUMAN; HUMAN TISSUE; HUNTINGTON CHOREA; IN VIVO STUDY; INFLAMMATION; MACROPHAGE ACTIVATION; MICROGLIA; MOUSE; MOUSE MODEL; NERVE CELL NECROSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSCRIPTION INITIATION;

ANIMALS; CELL DEATH; DISEASE MODELS, ANIMAL; DNA REPEAT EXPANSION; GENE KNOCK-IN TECHNIQUES; GENOME-WIDE ASSOCIATION STUDY; HUMANS; HUNTINGTON DISEASE; INFLAMMATION; MICE; MICE, TRANSGENIC; MICROGLIA; MUTATION; MYELOID CELLS; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS;

EID: 84897405847     PISSN: 10976256     EISSN: 15461726     Source Type: Journal    
DOI: 10.1038/nn.3668     Document Type: Article

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