Combination of honokiol and magnolol inhibits hepatic steatosis through AMPK-SREBP-1 c pathway

Experimental Biology and Medicine

Volumn 240, Issue 4, 2015, Pages 508-518

  Lee, Ju Hee ^a   Jung, Ji Yun ^a   Jang, Eun Jeong ^a   Jegal, Kyung Hwan ^a   Moon, Soo Young ^a   Ku, Sae Kwang ^a   Kang, Seung Ho ^a   Cho, Il Je ^a   Park, Sook Jahr ^a   Lee, Jong Rok ^a   Zhao, Rong Jie ^a,b   Kim, Sang Chan ^a   Kim, Young Woo ^a  

^a Daegu Haany University   (South Korea)

^b Mudanjiang Medical University   (South Korea)

Author keywords

AMP activated protein kinase; hepatic steatosis; Honokiol; magnolol; sterol regulatory element binding protein 1 c

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; ACYL COENZYME A DESATURASE; CARNITINE PALMITOYLTRANSFERASE I; FAS ANTIGEN; HONOKIOL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; LIVER X RECEPTOR ALPHA; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MAGNOLIA OFFICINALIS EXTRACT; MAGNOLOL; MESSENGER RNA; RECEPTOR BLOCKING AGENT; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; T090; UNCLASSIFIED DRUG; BIPHENYL DERIVATIVE; ENZYME INHIBITOR; LIGNAN; LIVER X RECEPTOR; ORPHAN NUCLEAR RECEPTOR; STEROL REGULATORY ELEMENT BINDING PROTEIN 1;

AGONIST; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL VIABILITY ASSAY; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; CYTOTOXICITY; FATTY LIVER; HISTOPATHOLOGY; HUMAN; HUMAN CELL; LIPID DIET; LIPOGENESIS; LIVER DYSFUNCTION; LUCIFERASE ASSAY; MALE; MOUSE; NONALCOHOLIC FATTY LIVER; NONHUMAN; REPORTER GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TOXIC HEPATITIS; TRANSIENT TRANSFECTION; WEIGHT GAIN; WESTERN BLOTTING; ADVERSE EFFECTS; ANIMAL; C57BL MOUSE; CELL LINE; CHEMICALLY INDUCED; DISEASE MODEL; DRUG COMBINATION; DRUG EFFECTS; DRUG POTENTIATION; LIVER CELL; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION;

MAGNOLIA OFFICINALIS; MUS;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; BIPHENYL COMPOUNDS; CELL LINE; DIET, HIGH-FAT; DISEASE MODELS, ANIMAL; DRUG SYNERGISM; DRUG THERAPY, COMBINATION; ENZYME INHIBITORS; FATTY LIVER; HEPATOCYTES; HUMANS; LIGNANS; LIPOGENESIS; MALE; MICE; MICE, INBRED C57BL; ORPHAN NUCLEAR RECEPTORS; SIGNAL TRANSDUCTION; STEROL REGULATORY ELEMENT BINDING PROTEIN 1;

EID: 84927785626     PISSN: 15353702     EISSN: 15353699     Source Type: Journal    
DOI: 10.1177/1535370214547123     Document Type: Article

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