Continuing treatment with Salvia miltiorrhiza injection attenuates myocardial fibrosis in chronic iron-overloaded mice

PLoS ONE

Volumn 10, Issue 4, 2015, Pages

  Zhang, Ying ^a   Wang, Hao ^a   Cui, Lijing ^a   Zhang, Yuanyuan ^b   Liu, Yang ^a   Chu, Xi ^a   Liu, Zhenyi ^b   Zhang, Jianping ^a   Chu, Li ^a  

^a HEBEI MEDICAL UNIVERSITY   (China)

^b HEBEI UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 1; COLLAGEN TYPE 3; DEFEROXAMINE; GELATINASE B; MALONALDEHYDE; SALVIA MILTIORRHIZA EXTRACT; SUPEROXIDE DISMUTASE; TRANSFORMING GROWTH FACTOR BETA1; VERAPAMIL; DAN-SHEN ROOT EXTRACT; HERBACEOUS AGENT; IRON; IRON DEXTRAN; MMP9 PROTEIN, MOUSE; PLANT EXTRACT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DRUG ACTIVITY; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG MEGADOSE; DRUG SAFETY; ENZYME ACTIVITY; HEART MUSCLE FIBROSIS; HEART WEIGHT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HOMEOSTASIS; HUMIDITY; IRON OVERLOAD; LOW DRUG DOSE; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PROTEIN CONTENT; PROTEIN EXPRESSION; UPREGULATION; ANIMAL; CHINESE MEDICINE; DRUG EFFECTS; ENDOMYOCARDIAL FIBROSIS; METABOLISM; PATHOLOGY; RANDOMIZATION; SALVIA MILTIORRHIZA;

ANIMALIA; MUS; SALVIA MILTIORRHIZA;

ANIMALS; COLLAGEN TYPE I; COLLAGEN TYPE III; DEFEROXAMINE; DRUGS, CHINESE HERBAL; ENDOMYOCARDIAL FIBROSIS; IRON; IRON OVERLOAD; IRON-DEXTRAN COMPLEX; MALONDIALDEHYDE; MATRIX METALLOPROTEINASE 9; MEDICINE, CHINESE TRADITIONAL; MICE; OXIDATIVE STRESS; PLANT EXTRACTS; RANDOM ALLOCATION; SALVIA MILTIORRHIZA; SUPEROXIDE DISMUTASE; TRANSFORMING GROWTH FACTOR BETA1; VERAPAMIL;

EID: 84927609327     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0124061     Document Type: Article

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