Salvia miltiorrhiza (Danshen) inhibits L-type calcium current and attenuates calcium transient and contractility in rat ventricular myocytes

Journal of Ethnopharmacology

Volumn , Issue PartA, 2014, Pages 397-403

  Gao, Yonggang ^a   Zhang, Kai ^b   Zhu, Fengli ^a   Wu, Zhonglin ^a   Chu, Xi ^a   Zhang, Xuan ^b   Zhang, Ying ^b   Zhang, Jianping ^b   Chu, Li ^a,b  

^a HEBEI MEDICAL UNIVERSITY   (China)

^b HEBEI UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Calcium transient; L type calcium current; Myocyte contractility; Patch clamp; SM

Indexed keywords

CALCIUM; CALCIUM CHANNEL L TYPE; SALVIA MILTIORRHIZA EXTRACT; CALCIUM CHANNEL BLOCKING AGENT; PLANT EXTRACT;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONDUCTANCE; CONTROLLED STUDY; DEPOLARIZATION; ELECTRIC POTENTIAL; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; MALE; NONHUMAN; RAT; SALVIA MILTIORRHIZA; STEADY STATE; WHOLE CELL PATCH CLAMP; ANIMAL; CHEMISTRY; CYTOLOGY; DOSE RESPONSE; DRUG EFFECTS; HEART VENTRICLE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METABOLISM; SPRAGUE DAWLEY RAT; ULTRAVIOLET SPECTROPHOTOMETRY;

RATTUS; SALVIA MILTIORRHIZA;

ANIMALS; CALCIUM; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS, L-TYPE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOSE-RESPONSE RELATIONSHIP, DRUG; HEART VENTRICLES; MALE; MYOCYTES, CARDIAC; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY; SALVIA MILTIORRHIZA; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 84911995607     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2014.10.049     Document Type: Article

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