Oxidative stress-dependent activation of collagen synthesis is induced in human pulmonary smooth muscle cells by sera from patients with scleroderma-associated pulmonary hypertension

Orphanet Journal of Rare Diseases

Volumn 9, Issue 1, 2014, Pages

  Boin, Francesco ^a   Erre, Gian Luca ^b   Posadino, Anna Maria ^b   Cossu, Annalisa ^b   Giordo, Roberta ^b   Spinetti, Gaia ^c   Passiu, Giuseppe ^b   Emanueli, Costanza ^d   Pintus, Gianfranco ^b  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b UNIVERSITY OF SASSARI   (Italy)

^c IRCCS MULTIMEDICA   (Italy)

^d UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

Oxidative stress; Pulmonary arterial hypertension; Systemic sclerosis; Vascular smooth muscle cells

Indexed keywords

COLLAGEN TYPE 1; POLYCYCLIC AROMATIC HYDROCARBON; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; COLLAGEN;

ADULT; ARTICLE; CELL ACTIVITY; COLLAGEN SYNTHESIS; FEMALE; HEART CATHETERIZATION; HUMAN; HUMAN CELL; LUNG ALVEOLUS CELL; LUNG ARTERY PRESSURE; MAJOR CLINICAL STUDY; MALE; OXIDATIVE STRESS; PILOT STUDY; PULMONARY ARTERY OCCLUSION PRESSURE; PULMONARY HYPERTENSION; SMOOTH MUSCLE FIBER; SYSTEMIC SCLEROSIS; BIOSYNTHESIS; BLOOD; COMPLICATION; CYTOLOGY; DIFFUSE SCLERODERMA; HYPERTENSION, PULMONARY; LUNG; METABOLISM; SMOOTH MUSCLE;

COLLAGEN; FEMALE; HUMANS; HYPERTENSION, PULMONARY; LUNG; MALE; MUSCLE, SMOOTH; OXIDATIVE STRESS; SCLERODERMA, DIFFUSE;

EID: 84906561129     PISSN: None     EISSN: 17501172     Source Type: Journal    
DOI: 10.1186/s13023-014-0123-7     Document Type: Article

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